Crystallographic analysis of Lac repressor bound to natural operator O1

Journal of Molecular Biology

Volumn 312, Issue 5, 2001, Pages 921-926

  Bell, Charles E ^a   Lewis, Mitchell ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

DNA bending; DNA binding; Gene regulation; Lac repressor; Protein DNA interactions

Indexed keywords

DNA; REPRESSOR PROTEIN;

ARTICLE; BASE PAIRING; CRYSTAL STRUCTURE; DNA DETERMINATION; OPERATOR; PRIORITY JOURNAL; PROTEIN DNA BINDING; STRUCTURE ANALYSIS; X RAY CRYSTALLOGRAPHY;

EID: 0035812627     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1006/jmbi.2001.5024     Document Type: Article

References (22)

1. The nucleotide sequence of the lac operator
2. A perfectly symmetric lac operator binds the lac repressor very tightly
3. Crystal structure of the lactose operon repressor and its complexes with DNA and inducer
4. A closer view of the conformation of the Lac repressor bound to operator
5. Formation of the hinge helix in the lac repressor is induced upon binding to the lac operator
6. The solution structure of Lac repressor headpiece 62 complexed to a symmetrical lac operator
7. DNA bending by negative regulatory proteins: Gal and Lac repressors
8. Hinge-helix formation and DNA bending in various lac repressor-operator complexes
9. The locus of sequence-directed and protein-induced DNA bending
10. DNA bend direction by phase sensitive detection
11. Strong DNA binding by covalently linked dimeric Lac headpiece: Evidence for the crucial role of the hinge helices
12. Structure of the complex of lac repressor headpiece and an 11 base-pair half-operator determined by nuclear magnetic resonance spectroscopy and restrained molecular dynamics
13. Crystal structure of lac repressor core tetramer and its implications for DNA looping
14. lac repressor-operator interaction. IX. The binding of lac repressor to operators containing Oc mutations
15. Processing of X-ray diffraction data collected in oscillation mode
16. AMoRe: An automated package for molecular replacement
17. Crystallography & NMR system: A new software suite for macromolecular structure determination
18. The free R value: A novel statistical quantity for assessing the accuracy of crystal structures
19. Molscript: A program to produce both detailed and schematic plots of protein structures
20. Raster3D: Photorealistic molecular graphics
21. Improved methods for building protein models in electron density maps and the location of errors in these models