Characterization of a novel, non-peptidyl antagonist of the human glucagon receptor

Journal of Biological Chemistry

Volumn 274, Issue 13, 1999, Pages 8694-8697

  Cascieri, Margaret A ^a   Koch, Gregory E ^a   Ber, Elzbieta ^a   Sadowski, Sharon J ^a   Louizides, Donna ^a   De Laszlo, Stephen E ^a   Hacker, Candice ^a   Hagmann, William K ^a   MacCoss, Malcolm ^a   Chicchi, Gary G ^a   Vicario, Pasquale P ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2 (4 PYRIDYL) 5 (4 CHLOROPHENYL) 3 (5 BROMO 2 PROPYLOXYPHENYL)PYRROLE; ADENYLATE CYCLASE; ANTIDIABETIC AGENT; DIVALENT CATION; GLUCAGON; GLUCAGON LIKE PEPTIDE; GLUCAGON RECEPTOR; L 168049; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BINDING AFFINITY; BINDING SITE; DOSE RESPONSE; DRUG ACTIVITY; DRUG ANTAGONISM; DRUG RECEPTOR BINDING; DRUG STRUCTURE; ENZYME ACTIVATION; MUTAGENESIS; NONHUMAN; PRIORITY JOURNAL; RECEPTOR OCCUPANCY;

ADENYLATE CYCLASE; ANIMALS; CATIONS, DIVALENT; CHO CELLS; CRICETINAE; ENZYME ACTIVATION; GLUCAGON-LIKE PEPTIDES; HORMONE ANTAGONISTS; HUMANS; MOLECULAR STRUCTURE; MUTATION; PEPTIDES; PROTEIN BINDING; PYRIDINES; PYRROLES; RECEPTORS, GLUCAGON;

ANIMALIA; CRICETINAE; CRICETULUS GRISEUS;

EID: 0033605578     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.274.13.8694     Document Type: Article

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