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Volumn 44, Issue 19, 2001, Pages 3141-3149

Identification of alkylidene hydrazides as glucagon receptor antagonists

(16) Ling, A a Hong, Y a Gonzalez, J a Gregor, V a Polinsky, A a Kuki, A a Shi, S a Teston, K a Murphy, D a Porter, J a Kiel, D a Lakis, J a Anderes, K a May, J a Knudsen, L B b Lau, J b

a PFIZER GLOBAL RESEARCH AND DEVELOPMENT (United States)

b NOVO NORDISK A S (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

3 CHLORO 5 HYDROXY N' [(4 HYDROXY 1 NAPHTHYL)METHYLIDENE]BENZOHYDRAZIDE; GLUCAGON; GLUCAGON RECEPTOR; GLUCOSE; HORMONE RECEPTOR BLOCKING AGENT; HYDRAZIDE DERIVATIVE; NAPHTHALENE DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; COMBINATORIAL CHEMISTRY; CONTROLLED STUDY; DRUG SCREENING; DRUG STRUCTURE; DRUG SYNTHESIS; HYPERGLYCEMIA; MALE; NONHUMAN; RAT; RECEPTOR BLOCKING;

ANIMALS; BENZAMIDES; BINDING, COMPETITIVE; BLOOD GLUCOSE; CELL LINE; COMBINATORIAL CHEMISTRY TECHNIQUES; CYCLIC AMP; GLUCAGON; HUMANS; HYDRAZONES; LIVER; MALE; RADIOLIGAND ASSAY; RATS; RATS, SPRAGUE-DAWLEY; RATS, WISTAR; RECEPTORS, GLUCAGON; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0035855876 PISSN: 00222623 EISSN: None Source Type: Journal
DOI: 10.1021/jm000547o Document Type: Article

Times cited : (50)

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