Metal ion-mediated agonism and agonist enhancement in melanocortin MC1 and MC4 receptors

Journal of Biological Chemistry

Volumn 277, Issue 49, 2002, Pages 47662-47670

  Holst, Birgitte ^a,b   Elling, Christian E ^b   Schwartz, Thue W ^a,b  

^a UNIVERSITY OF COPENHAGEN   (Denmark)

^b 7TM Pharma A S   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

ADDITIVES; CHELATION; HORMONES; IONS;

MELANOCORTIN;

BIOCHEMISTRY;

1,10 PHENANTHROLINE; 2,2' BIPYRIDINE; ALPHA INTERMEDIN; ASPARTIC ACID; CHELATING AGENT; CYCLIC AMP; CYSTEINE; LIGAND; MELANOCORTIN 1 RECEPTOR; MELANOCORTIN 4 RECEPTOR; METAL ION; PROTEIN; ZINC CHLORIDE;

AGONIST; ANIMAL CELL; ARTICLE; BINDING AFFINITY; BINDING SITE; CELL STRAIN COS7; CONTROLLED STUDY; DOSE RESPONSE; HYDROPHOBICITY; NONHUMAN; PRIORITY JOURNAL;

AMINO ACID SEQUENCE; ANIMALS; BINDING, COMPETITIVE; BRAIN; COS CELLS; CYCLIC AMP; CYSTEINE; DNA, COMPLEMENTARY; DOSE-RESPONSE RELATIONSHIP, DRUG; HUMANS; INHIBITORY CONCENTRATION 50; IONS; KINETICS; LIGANDS; METALS; MICE; MODELS, CHEMICAL; MOLECULAR SEQUENCE DATA; MUTATION; PEPTIDES; PROTEIN BINDING; PROTEIN STRUCTURE, SECONDARY; RECEPTOR, MELANOCORTIN, TYPE 4; RECEPTORS, CORTICOTROPIN; RECEPTORS, MELANOCORTIN; TRANSFECTION; TUMOR CELLS, CULTURED; ZINC;

ANIMALIA;

EID: 0346259943     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M202103200     Document Type: Article

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