X-Ray Crystal Structure of Mycobacterium tuberculosis β-Ketoacyl Acyl Carrier Protein Synthase II (mtKasB)

Journal of Molecular Biology

Volumn 366, Issue 2, 2007, Pages 469-480

  Sridharan, Sudharsan ^a   Wang, Lei ^a   Brown, Alistair K ^b   Dover, Lynn G ^b   Kremer, Laurent ^c   Besra, Gurdyal S ^b   Sacchettini, James C ^a  

^a TEXAS A AND M UNIVERSITY   (United States)

^b UNIVERSITY OF BIRMINGHAM   (United Kingdom)

^c UNIV MONTPELLIER   (France)

Author keywords

drug target; FAS II; fatty acid biosynthesis; mtKasB; thiolactomycin

Indexed keywords

3 OXOACYL ACYL CARRIER PROTEIN SYNTHASE; ACETYL COENZYME A ACETYLTRANSFERASE; MYCOLIC ACID; THIOLACTOMYCIN; TUBERCULOSTATIC AGENT;

ARTICLE; BINDING AFFINITY; CRYSTAL STRUCTURE; DRUG TARGETING; ENZYME ACTIVE SITE; ENZYME ASSAY; ENZYME INHIBITION; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; POLYMERIZATION; PRIORITY JOURNAL; X RAY CRYSTALLOGRAPHY;

CORYNEBACTERINEAE; MYCOBACTERIUM TUBERCULOSIS;

EID: 33846412588     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jmb.2006.11.006     Document Type: Article

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