The 1.8 Å crystal structure and active-site architecture of β- ketoacyl-acyl carrier protein synthase III (FabH) from Escherichia coli

Structure

Volumn 8, Issue 2, 2000, Pages 185-195

  Davies, Christopher ^a   Heath, Richard J ^a   White, Stephen W ^a,b   Rock, Charles O ^a,b  

^a ST JUDE CHILDREN S RESEARCH HOSPITAL   (United States)

^b UNIVERSITY OF TENNESSEE HEALTH SCIENCE CENTER   (United States)

Author keywords

Acyl carrier protein; Coenzyme A; Condensing enzymes; Crystal structure; Fatty acids

Indexed keywords

3 OXOACYL ACYL CARRIER PROTEIN SYNTHASE; FATTY ACID SYNTHASE; 3 KETOACYL ACYL CARRIER PROTEIN SYNTHASE III; 3-KETOACYL-ACYL CARRIER PROTEIN SYNTHASE III; PRIMER DNA;

ACYLATION; ARTICLE; CONTROLLED STUDY; CRYSTAL STRUCTURE; DECARBOXYLATION; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME MECHANISM; ENZYME REGULATION; ENZYME STRUCTURE; ESCHERICHIA COLI; HYDROGEN BOND; NEGATIVE FEEDBACK; PRIORITY JOURNAL; SITE DIRECTED MUTAGENESIS; STRUCTURE ANALYSIS; AMINO ACID SEQUENCE; BINDING SITE; CATALYSIS; CHEMICAL STRUCTURE; CHEMISTRY; ENZYMOLOGY; GENETICS; METABOLISM; MOLECULAR GENETICS; NUCLEOTIDE SEQUENCE; PROTEIN CONFORMATION; X RAY CRYSTALLOGRAPHY;

BACTERIA (MICROORGANISMS); ESCHERICHIA COLI;

3-OXOACYL-(ACYL-CARRIER-PROTEIN) SYNTHASE; AMINO ACID SEQUENCE; BASE SEQUENCE; BINDING SITES; CATALYSIS; CRYSTALLOGRAPHY, X-RAY; DNA PRIMERS; ESCHERICHIA COLI; HYDROGEN BONDING; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; PROTEIN CONFORMATION;

EID: 0034651317     PISSN: 09692126     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0969-2126(00)00094-0     Document Type: Article

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