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Volumn 23, Issue 16, 2003, Pages 6470-6474

Endogenous interleukin-1 receptor antagonist mediates anti-inflammatory and neuroprotective actions of cannabinoids in neurons and glia

Author keywords

Cannabinoid; Cytokine; Excitotoxicity; IL 1ra; Neuroprotection; Nitric oxide

Indexed keywords

ALPHA AMINO 3 HYDROXY 5 METHYL 4 ISOXAZOLEPROPIONIC ACID; BACTERIUM LIPOPOLYSACCHARIDE; CANNABINOID; CANNABINOID 1 RECEPTOR; CANNABINOID 2 RECEPTOR; GLUTAMATE RECEPTOR; INTERLEUKIN 1; INTERLEUKIN 1 RECEPTOR; INTERLEUKIN 1 RECEPTOR BLOCKING AGENT; N METHYL DEXTRO ASPARTIC ACID; NITRIC OXIDE;

EID: 0041842648     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/jneurosci.23-16-06470.2003     Document Type: Article
Times cited : (177)

References (30)
  • 1
    • 0035487313 scopus 로고    scopus 로고
    • Cytokines and acute neurodegeneration
    • Allan SM, Rothwell NJ (2001) Cytokines and acute neurodegeneration. Nat Rev Neurosci 2:734-744.
    • (2001) Nat Rev Neurosci , vol.2 , pp. 734-744
    • Allan, S.M.1    Rothwell, N.J.2
  • 2
    • 0035676046 scopus 로고    scopus 로고
    • Cannabinoid-mediated inhibition of inducible nitric oxide production by rat microglial cells: Evidence for CB1 receptor participation
    • Cabral GA, Harmon KN, Carlisle SJ (2001) Cannabinoid-mediated inhibition of inducible nitric oxide production by rat microglial cells: evidence for CB1 receptor participation. Adv Exp Med Biol 493:207-214.
    • (2001) Adv Exp Med Biol , vol.493 , pp. 207-214
    • Cabral, G.A.1    Harmon, K.N.2    Carlisle, S.J.3
  • 3
    • 0032978333 scopus 로고    scopus 로고
    • The progression and topographic distribution of interleukin-1beta expression after permanent middle cerebral artery occlusion in the rat
    • Davies CA, Loddick SA, Toulmond S, Stroemer RP, Hunt J, Rothwell NJ (1999) The progression and topographic distribution of interleukin-1beta expression after permanent middle cerebral artery occlusion in the rat. J Cereb Blood Flow Metab 19:87-98.
    • (1999) J Cereb Blood Flow Metab , vol.19 , pp. 87-98
    • Davies, C.A.1    Loddick, S.A.2    Toulmond, S.3    Stroemer, R.P.4    Hunt, J.5    Rothwell, N.J.6
  • 4
    • 0026056197 scopus 로고
    • Blocking IL-1: Interleukin 1 receptor antagonist in vivo and in vitro
    • Dinarello CA, Thompson RC (1991) Blocking IL-1: interleukin 1 receptor antagonist in vivo and in vitro. Immunol Today 12:404-410.
    • (1991) Immunol Today , vol.12 , pp. 404-410
    • Dinarello, C.A.1    Thompson, R.C.2
  • 6
    • 0032493197 scopus 로고    scopus 로고
    • Cannabidiol and (-)Delta9-tetrahydrocannabinol are neuroprotective antioxidants
    • Hampson AJ, Grimaldi M, Axelrod J, Wink D (1998) Cannabidiol and (-)Delta9-tetrahydrocannabinol are neuroprotective antioxidants. Proc Natl Acad Sci USA 95:8268-8273.
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 8268-8273
    • Hampson, A.J.1    Grimaldi, M.2    Axelrod, J.3    Wink, D.4
  • 7
    • 0032948112 scopus 로고    scopus 로고
    • Inhibition of nitric oxide synthase as a potential therapeutic target
    • Hobbs AJ, Higgs A, Moncada S (1999) Inhibition of nitric oxide synthase as a potential therapeutic target. Annu Rev Pharmacol Toxicol 39:191-220.
    • (1999) Annu Rev Pharmacol Toxicol , vol.39 , pp. 191-220
    • Hobbs, A.J.1    Higgs, A.2    Moncada, S.3
  • 8
    • 0032482168 scopus 로고    scopus 로고
    • Production of mice deficient in genes for interleukin (IL)-1alpha, IL-1beta, IL-1alpha/beta, and IL-1 receptor antagonist shows that IL-1beta is crucial in turpentine-induced fever development and glucocorticoid secretion
    • Horai R, Asano M, Sudo K, Kanuka H, Suzuki M, Nishihara M, Takahashi M, Iwakura Y (1998) Production of mice deficient in genes for interleukin (IL)-1alpha, IL-1beta, IL-1alpha/beta, and IL-1 receptor antagonist shows that IL-1beta is crucial in turpentine-induced fever development and glucocorticoid secretion. J Exp Med 187:1463-1475.
    • (1998) J Exp Med , vol.187 , pp. 1463-1475
    • Horai, R.1    Asano, M.2    Sudo, K.3    Kanuka, H.4    Suzuki, M.5    Nishihara, M.6    Takahashi, M.7    Iwakura, Y.8
  • 14
    • 0026603679 scopus 로고
    • Cannabinoids inhibit N-type calcium channels in neuroblastoma-glioma cells
    • Mackie K, Hille B (1992) Cannabinoids inhibit N-type calcium channels in neuroblastoma-glioma cells. Proc Natl Acad Sci USA 89:3825-3829.
    • (1992) Proc Natl Acad Sci USA , vol.89 , pp. 3825-3829
    • Mackie, K.1    Hille, B.2
  • 15
    • 0036156353 scopus 로고    scopus 로고
    • Cannabinoids and brain injury: Therapeutic implications
    • Mechoulam R, Panikashvili D, Shohami E (2002a) Cannabinoids and brain injury: therapeutic implications. Trends Mol Med 8:58-61.
    • (2002) Trends Mol Med , vol.8 , pp. 58-61
    • Mechoulam, R.1    Panikashvili, D.2    Shohami, E.3
  • 17
    • 0030795910 scopus 로고    scopus 로고
    • Anandamide suppresses nitric oxide and TNF-alpha responses to Theiler's virus or endotoxin in astrocytes
    • Molina-Holgado F, Lledo A, Guaza C (1997) Anandamide suppresses nitric oxide and TNF-alpha responses to Theiler's virus or endotoxin in astrocytes. NeuroReport 8:1929-1933.
    • (1997) NeuroReport , vol.8 , pp. 1929-1933
    • Molina-Holgado, F.1    Lledo, A.2    Guaza, C.3
  • 18
    • 0031866598 scopus 로고    scopus 로고
    • The endogenous cannabinoid anandamide potentiates interleukin-6 production by astrocytes infected with Theiler's murine encephalomyelitis virus by a receptor-mediated pathway
    • Molina-Holgado F, Molina-Holgado E, Guaza C (1998) The endogenous cannabinoid anandamide potentiates interleukin-6 production by astrocytes infected with Theiler's murine encephalomyelitis virus by a receptor-mediated pathway. FEBS Lett 433:139-142.
    • (1998) FEBS Lett , vol.433 , pp. 139-142
    • Molina-Holgado, F.1    Molina-Holgado, E.2    Guaza, C.3
  • 19
    • 0037085572 scopus 로고    scopus 로고
    • Role of CB1 and CB2 receptors in the inhibitory effects of cannabinoids on lipopolysaccharide induced nitric oxide release in astrocyte cultures
    • Molina-Holgado F, Molina-Holgado E, Guaza C, Rothwell NJ (2002) Role of CB1 and CB2 receptors in the inhibitory effects of cannabinoids on lipopolysaccharide induced nitric oxide release in astrocyte cultures. J Neurosci Res 67:829-836.
    • (2002) J Neurosci Res , vol.67 , pp. 829-836
    • Molina-Holgado, F.1    Molina-Holgado, E.2    Guaza, C.3    Rothwell, N.J.4
  • 20
    • 0036186039 scopus 로고    scopus 로고
    • Involvement of caspases and calpains in cerebrocortical neuronal cell death is stimulus-dependent
    • Moore JD, Rothwell NJ, Gibson RM (2002) Involvement of caspases and calpains in cerebrocortical neuronal cell death is stimulus-dependent. Br J Pharmacol 135:1069-1077.
    • (2002) Br J Pharmacol , vol.135 , pp. 1069-1077
    • Moore, J.D.1    Rothwell, N.J.2    Gibson, R.M.3
  • 21
    • 0027329873 scopus 로고
    • 45Ca2+ influx through the N-methyl-D-aspartate receptor ion channel by the nonpsychoactive cannabinoid HU-211
    • 45Ca2+ influx through the N-methyl-D-aspartate receptor ion channel by the nonpsychoactive cannabinoid HU-211. Brain Res 622:79-85.
    • (1993) Brain Res , vol.622 , pp. 79-85
    • Nadler, V.1    Mechoulam, R.2    Sokolovsky, M.3
  • 22
    • 0033561159 scopus 로고    scopus 로고
    • Cannabinoids and neuroprotection in global and focal cerebral ischemia and in neuronal cultures
    • Nagayama T, Sinor AD, Simon RP, Chen J, Graham SH, Jin K, Greenberg DA (1999) Cannabinoids and neuroprotection in global and focal cerebral ischemia and in neuronal cultures. J Neurosci 19:2987-2995.
    • (1999) J Neurosci , vol.19 , pp. 2987-2995
    • Nagayama, T.1    Sinor, A.D.2    Simon, R.P.3    Chen, J.4    Graham, S.H.5    Jin, K.6    Greenberg, D.A.7
  • 24
    • 0036669791 scopus 로고    scopus 로고
    • Cannabinoids and multiple sclerosis
    • Pertwee RG (2002) Cannabinoids and multiple sclerosis. Pharmacol Ther 95:165-174.
    • (2002) Pharmacol Ther , vol.95 , pp. 165-174
    • Pertwee, R.G.1
  • 25
    • 0033986604 scopus 로고    scopus 로고
    • Cannabinoids inhibit LPS-inducible cy-tokine mRNA expression in rat microglial cells
    • Puffenbarger RA, Boothe AC, Cabral GA (2000) Cannabinoids inhibit LPS-inducible cy-tokine mRNA expression in rat microglial cells. Glia 29:58-69.
    • (2000) Glia , vol.29 , pp. 58-69
    • Puffenbarger, R.A.1    Boothe, A.C.2    Cabral, G.A.3
  • 26
    • 0028982492 scopus 로고
    • Contribution of interleukin-1 to the inflammation-induced increase in nerve growth factor levels and inflammatory hyperalgesia
    • Safieh-Garabedian B, Poole S, Allchorne A, Winter J, Woolf CJ (1995) Contribution of interleukin-1 to the inflammation-induced increase in nerve growth factor levels and inflammatory hyperalgesia. Br J Pharmacol 115:1265-1275.
    • (1995) Br J Pharmacol , vol.115 , pp. 1265-1275
    • Safieh-Garabedian, B.1    Poole, S.2    Allchorne, A.3    Winter, J.4    Woolf, C.J.5
  • 27
    • 0031706164 scopus 로고    scopus 로고
    • Cannabinoid receptor agonists protect cultured rat hippocampal neurons from excitotoxicity
    • Shen M, Thayer SA (1998) Cannabinoid receptor agonists protect cultured rat hippocampal neurons from excitotoxicity. Mol Pharmacol 54:459-462.
    • (1998) Mol Pharmacol , vol.54 , pp. 459-462
    • Shen, M.1    Thayer, S.A.2
  • 28
    • 0031047431 scopus 로고    scopus 로고
    • Cytokine production in the brain following closed head injury: Dexanabinol (HU-211) is a novel TNF-alpha inhibitor and an effective neuroprotectant
    • Shohami E, Gallily R, Mechoulam R, Bass R, Ben-Hur T (1997) Cytokine production in the brain following closed head injury: dexanabinol (HU-211) is a novel TNF-alpha inhibitor and an effective neuroprotectant. J Neuroimmunol 72:169-177.
    • (1997) J Neuroimmunol , vol.72 , pp. 169-177
    • Shohami, E.1    Gallily, R.2    Mechoulam, R.3    Bass, R.4    Ben-Hur, T.5
  • 30
    • 0036889699 scopus 로고    scopus 로고
    • Delta 9-Tetrahydrocannabinol regulates Tb1/Tb2 cytokine balance in activated human T cells
    • Yuan M, Kiertscher SM, Cheng Q, Zoumalan R, Tashkin DP, Roth MD (2002) Delta 9-Tetrahydrocannabinol regulates Tb1/Tb2 cytokine balance in activated human T cells. J Neuroimmunol 133:124-131.
    • (2002) J Neuroimmunol , vol.133 , pp. 124-131
    • Yuan, M.1    Kiertscher, S.M.2    Cheng, Q.3    Zoumalan, R.4    Tashkin, D.P.5    Roth, M.D.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.