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Volumn 36, Issue 5, 2004, Pages 461-467

Protein kinase A mediates microglial activation induced by plasminogen and gangliosides

Author keywords

Brain inflammation; cAMP response element binding protein (CREB); Gangliosides; Microglia; Plasminogen; Protein kinase A

Indexed keywords

CYCLIC AMP DEPENDENT PROTEIN KINASE; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN BINDING PROTEIN; GANGLIOSIDE; INDUCIBLE NITRIC OXIDE SYNTHASE; KT 5720; N [2 (4 BROMOCINNAMYLAMINO)ETHYL] 5 ISOQUINOLINESULFONAMIDE; NITRIC OXIDE SYNTHASE; PLASMINOGEN;

EID: 9344231936     PISSN: 12263613     EISSN: 20926413     Source Type: Journal    
DOI: 10.1038/emm.2004.58     Document Type: Article
Times cited : (23)

References (41)
  • 2
    • 0025233694 scopus 로고
    • Immortalization of murine microglial cells by a v-raf/v-myc carrying retrovirus
    • Blasi E, Baduzzi R, Bocchini V, Mazzolla R, Bistoni F. Immortalization of murine microglial cells by a v-raf/v-myc carrying retrovirus. J Neuroimmunol 1990;27:229-37
    • (1990) J Neuroimmunol , vol.27 , pp. 229-237
    • Blasi, E.1    Baduzzi, R.2    Bocchini, V.3    Mazzolla, R.4    Bistoni, F.5
  • 3
    • 0030949820 scopus 로고    scopus 로고
    • Cyclic AMP potentiation of cytokine-induced nitric oxide synthase activity in a murine astrocyte cell line
    • Burgher KL, Heroux JA, Ringheim GE. Cyclic AMP potentiation of cytokine-induced nitric oxide synthase activity in a murine astrocyte cell line. Neurochem Int 1997;30:483-9
    • (1997) Neurochem Int , vol.30 , pp. 483-489
    • Burgher, K.L.1    Heroux, J.A.2    Ringheim, G.E.3
  • 5
    • 4644276786 scopus 로고    scopus 로고
    • Nitric oxide suppresses inducible nitric oxide synthase expression by inhibiting post-translational modification of IkappaB
    • Chang K, Lee SJ, Cheong I, Billiar TR, Chung HT, Han JA, Kwon YG, Ha KS, Kim YM. Nitric oxide suppresses inducible nitric oxide synthase expression by inhibiting post-translational modification of IkappaB. Exp Mol Med 2004;36:311-4
    • (2004) Exp Mol Med , vol.36 , pp. 311-314
    • Chang, K.1    Lee, S.J.2    Cheong, I.3    Billiar, T.R.4    Chung, H.T.5    Han, J.A.6    Kwon, Y.G.7    Ha, K.S.8    Kim, Y.M.9
  • 6
    • 0038383698 scopus 로고    scopus 로고
    • Thrombin-induced microglial activation produces degeneration of nigral dopaminergic neurons in vivo
    • Choi SH, Joe EH, Kim SU, Jin BK. Thrombin-induced microglial activation produces degeneration of nigral dopaminergic neurons in vivo. J Neurosci 2003;23:5877-86
    • (2003) J Neurosci , vol.23 , pp. 5877-5886
    • Choi, S.H.1    Joe, E.H.2    Kim, S.U.3    Jin, B.K.4
  • 7
    • 0025260779 scopus 로고
    • Regulation of tumor necrosis factor alpha transcription in macrophages: Involvement of four kappa B-like motifs and of constitutive and inducible forms of NF-kappa B
    • Collart MA, Baeuerle P, Vassalli P. Regulation of tumor necrosis factor alpha transcription in macrophages: involvement of four kappa B-like motifs and of constitutive and inducible forms of NF-kappa B. Mol Cell Biol 1990;10:1498-506
    • (1990) Mol Cell Biol , vol.10 , pp. 1498-1506
    • Collart, M.A.1    Baeuerle, P.2    Vassalli, P.3
  • 8
    • 0014207441 scopus 로고
    • Gangliosides in isolated neurons and glial cells
    • Derry DM, Wolfe LS. Gangliosides in isolated neurons and glial cells. Science 1967;158:1450-2
    • (1967) Science , vol.158 , pp. 1450-1452
    • Derry, D.M.1    Wolfe, L.S.2
  • 9
    • 0032525028 scopus 로고    scopus 로고
    • Molecular mechanisms of inducible nitric oxide synthase gene expression by IL-1beta and cAMP in rat mesangial cells
    • Eberhardt W, Pluss C, Hummel R, Pfeilschifter J. Molecular mechanisms of inducible nitric oxide synthase gene expression by IL-1beta and cAMP in rat mesangial cells. J Immunol 1998;160:4961-9
    • (1998) J Immunol , vol.160 , pp. 4961-4969
    • Eberhardt, W.1    Pluss, C.2    Hummel, R.3    Pfeilschifter, J.4
  • 10
    • 0032779378 scopus 로고    scopus 로고
    • Regulation of the expression of the inflammatory nitric oxide synthase (NOS2) by cyclic AMP
    • Galea E, Feinstein DL. Regulation of the expression of the inflammatory nitric oxide synthase (NOS2) by cyclic AMP. FASEB J 1999;13:2125-37
    • (1999) FASEB J , vol.13 , pp. 2125-2137
    • Galea, E.1    Feinstein, D.L.2
  • 11
    • 0022441440 scopus 로고
    • Interleukin 1 of the central nervous system is produced by ameboid microglia
    • Giulian D, Baker TJ, Shih LC, Lachman LB. Interleukin 1 of the central nervous system is produced by ameboid microglia. J Exp Med 1986;164:594-604
    • (1986) J Exp Med , vol.164 , pp. 594-604
    • Giulian, D.1    Baker, T.J.2    Shih, L.C.3    Lachman, L.B.4
  • 12
    • 0026069242 scopus 로고
    • Microglial mitogens are produced in the developing and injured mammalian brain
    • Giulian D, Johnson B, Krebs JF, George JK, Tapscott M. Microglial mitogens are produced in the developing and injured mammalian brain. J Cell Biol 1991;112:323-33
    • (1991) J Cell Biol , vol.112 , pp. 323-333
    • Giulian, D.1    Johnson, B.2    Krebs, J.F.3    George, J.K.4    Tapscott, M.5
  • 13
    • 0032942060 scopus 로고    scopus 로고
    • Microglia as mediators of inflammatory and degenerative diseases
    • Gonzalez-Scarano F, Baltuch G. Microglia as mediators of inflammatory and degenerative diseases. Annu Rev Neurosci 1999;22:219-40
    • (1999) Annu Rev Neurosci , vol.22 , pp. 219-240
    • Gonzalez-Scarano, F.1    Baltuch, G.2
  • 15
    • 0028345042 scopus 로고
    • Induction of nitric oxide synthase by cyclic AMP in rat vascular smooth muscle cells
    • Imai T, Hirata Y, Kanno K, Marumo F. Induction of nitric oxide synthase by cyclic AMP in rat vascular smooth muscle cells. J Clin Invest 1994;93:543-9
    • (1994) J Clin Invest , vol.93 , pp. 543-549
    • Imai, T.1    Hirata, Y.2    Kanno, K.3    Marumo, F.4
  • 16
    • 0037174916 scopus 로고    scopus 로고
    • JAK-STAT signaling mediates gangliosides-induced inflammatory responses in brain microglial cells
    • Kim OS, Park EJ, Joe EH, Jou I. JAK-STAT signaling mediates gangliosides-induced inflammatory responses in brain microglial cells. J Biol Chem 2002;277:40594-601
    • (2002) J Biol Chem , vol.277 , pp. 40594-40601
    • Kim, O.S.1    Park, E.J.2    Joe, E.H.3    Jou, I.4
  • 17
    • 0030734515 scopus 로고    scopus 로고
    • Transcriptional regulation of inducible nitric oxide synthase in cultured neonatal rat cardiac myocytes
    • Kinugawa K, Shimizu T, Yao A, Kohmoto O, Serizawa T, Takahashi T. Transcriptional regulation of inducible nitric oxide synthase in cultured neonatal rat cardiac myocytes. Circ Res 1997;81:911-21
    • (1997) Circ Res , vol.81 , pp. 911-921
    • Kinugawa, K.1    Shimizu, T.2    Yao, A.3    Kohmoto, O.4    Serizawa, T.5    Takahashi, T.6
  • 18
    • 0027298505 scopus 로고
    • Cytokine production by human fetal microglia and astrocytes. Differential induction by lipopolysaccharide and IL-1 beta
    • Lee SC, Liu W, Dickson DW, Brosnan CF, Berman JW. Cytokine production by human fetal microglia and astrocytes. Differential induction by lipopolysaccharide and IL-1 beta. J Immunol 1993;150:2659-67
    • (1993) J Immunol , vol.150 , pp. 2659-2667
    • Lee, S.C.1    Liu, W.2    Dickson, D.W.3    Brosnan, C.F.4    Berman, J.W.5
  • 19
    • 0344495393 scopus 로고    scopus 로고
    • Plasminogen-induced IL-1beta and TNF-alpha production in microglia is regulated by reactive oxygen species
    • Min KJ, Jou I, Joe E. Plasminogen-induced IL-1beta and TNF-alpha production in microglia is regulated by reactive oxygen species. Biochem Biophys Res Commun 2003;312:969-74
    • (2003) Biochem Biophys Res Commun , vol.312 , pp. 969-974
    • Min, K.J.1    Jou, I.2    Joe, E.3
  • 20
    • 9144256818 scopus 로고    scopus 로고
    • Gangliosides activate microglia via protein kinase C and NADPH oxidase
    • In press
    • Min KJ, Pyo HK, Yang MS, Ji KA, Jou I, Joe E. Gangliosides activate microglia via protein kinase C and NADPH oxidase. Glia 2004; In press
    • (2004) Glia
    • Min, K.J.1    Pyo, H.K.2    Yang, M.S.3    Ji, K.A.4    Jou, I.5    Joe, E.6
  • 21
    • 0028805463 scopus 로고
    • Induction of prostanoid biosynthesis by bacterial lipopolysaccharide and isoproterenol in rat microglial cultures
    • Minghetti L, Levi G. Induction of prostanoid biosynthesis by bacterial lipopolysaccharide and isoproterenol in rat microglial cultures. J Neurochem 1995;65:2690-8
    • (1995) J Neurochem , vol.65 , pp. 2690-2698
    • Minghetti, L.1    Levi, G.2
  • 22
    • 0031081781 scopus 로고    scopus 로고
    • Inducible nitric oxide synthase expression in activated rat microglial cultures is downregulated by exogenous prostaglandin E2 and by cyclooxygenase inhibitors
    • Minghetti L, Nicolini A, Polazzi E, Creminon C, Maclouf J, Levi G. Inducible nitric oxide synthase expression in activated rat microglial cultures is downregulated by exogenous prostaglandin E2 and by cyclooxygenase inhibitors. Glia 1997;19:152-60
    • (1997) Glia , vol.19 , pp. 152-160
    • Minghetti, L.1    Nicolini, A.2    Polazzi, E.3    Creminon, C.4    Maclouf, J.5    Levi, G.6
  • 23
    • 0027386940 scopus 로고
    • Characterization of microglial reaction after middle cerebral artery occlusion in rat brain
    • Morioka T, Kalehua AN, Streit WJ. Characterization of microglial reaction after middle cerebral artery occlusion in rat brain. J Comp Neurol 1993;327:123-32
    • (1993) J Comp Neurol , vol.327 , pp. 123-132
    • Morioka, T.1    Kalehua, A.N.2    Streit, W.J.3
  • 24
    • 0027287397 scopus 로고
    • Role of protein kinase A in LPS-induced activation of NF-kappa B proteins of a mouse macrophage-like cell line, J774
    • Muroi M, Suzuki T. Role of protein kinase A in LPS-induced activation of NF-kappa B proteins of a mouse macrophage-like cell line, J774. Cell Signal 1993;5:289-98
    • (1993) Cell Signal , vol.5 , pp. 289-298
    • Muroi, M.1    Suzuki, T.2
  • 25
    • 0032570813 scopus 로고    scopus 로고
    • Expression of nitric-oxide synthase in rat Kupffer cells is regulated by cAMP
    • Mustafa SB, Olson MS. Expression of nitric-oxide synthase in rat Kupffer cells is regulated by cAMP. J Biol Chem 1998;273:5073-80
    • (1998) J Biol Chem , vol.273 , pp. 5073-5080
    • Mustafa, S.B.1    Olson, M.S.2
  • 26
    • 0029779964 scopus 로고    scopus 로고
    • Protein kinase A activation is required for IL-1-induced nitric oxide production by cardiac myocytes
    • Oddis CV, Simmons RL, Hattler BG, Finkel MS. Protein kinase A activation is required for IL-1-induced nitric oxide production by cardiac myocytes. Am J Physiol 1996;27: C429-C34
    • (1996) Am J Physiol , vol.27
    • Oddis, C.V.1    Simmons, R.L.2    Hattler, B.G.3    Finkel, M.S.4
  • 27
    • 0019495452 scopus 로고
    • Correlation of the biologic responses of C3H/HEJ mice to endotoxin with the chemical and structural properties of the lipopolysaccharides from Pseudomonas aeruginosa and Escherichia coli
    • Pier GB, Markham RB, Eardley D. Correlation of the biologic responses of C3H/HEJ mice to endotoxin with the chemical and structural properties of the lipopolysaccharides from Pseudomonas aeruginosa and Escherichia coli. J Immunol 1981;127:184-91
    • (1981) J Immunol , vol.127 , pp. 184-191
    • Pier, G.B.1    Markham, R.B.2    Eardley, D.3
  • 28
    • 0031592853 scopus 로고    scopus 로고
    • Expression and function of outward K+ channels induced by lipopolysaccharide in microglia
    • Pyo H, Chung S, Jou I, Gwag B, Joe EH. Expression and function of outward K+ channels induced by lipopolysaccharide in microglia. Mol Cells 1997;7:610-4
    • (1997) Mol Cells , vol.7 , pp. 610-614
    • Pyo, H.1    Chung, S.2    Jou, I.3    Gwag, B.4    Joe, E.H.5
  • 29
    • 0032579949 scopus 로고    scopus 로고
    • Mitogen-activated protein kinases activated by lipopolysaccharide and beta-amyloid in cultured rat microglia
    • Pyo H, Jou I, Jung S, Hong S, Joe EH. Mitogen-activated protein kinases activated by lipopolysaccharide and beta-amyloid in cultured rat microglia. Neuroreport 1998;9:871-4
    • (1998) Neuroreport , vol.9 , pp. 871-874
    • Pyo, H.1    Jou, I.2    Jung, S.3    Hong, S.4    Joe, E.H.5
  • 30
    • 0033520940 scopus 로고    scopus 로고
    • Gangliosides activate cultured rat brain microglia
    • Pyo H, Joe E, Jung S, Lee SH, Jou I. Gangliosides activate cultured rat brain microglia. J Biol Chem 1999a;274:34584-9
    • (1999) J Biol Chem , vol.274 , pp. 34584-34589
    • Pyo, H.1    Joe, E.2    Jung, S.3    Lee, S.H.4    Jou, I.5
  • 31
    • 0033580101 scopus 로고    scopus 로고
    • cAMP potentiates beta-amyloid-induced nitric oxide release from microglia
    • Pyo H, Jou I, Jung S, Joe E. cAMP potentiates beta-amyloid-induced nitric oxide release from microglia. Neuroreport 1999b;10:37-40
    • (1999) Neuroreport , vol.10 , pp. 37-40
    • Pyo, H.1    Jou, I.2    Jung, S.3    Joe, E.4
  • 32
    • 0034730753 scopus 로고    scopus 로고
    • Thrombin induces NO release from cultured rat microglia via protein kinase C, mitogen-activated protein kinase, and NF-kappa B
    • Ryu J, Pyo H, Jou I, Joe E. Thrombin induces NO release from cultured rat microglia via protein kinase C, mitogen-activated protein kinase, and NF-kappa B. J Biol Chem 2000;275:29955-9
    • (2000) J Biol Chem , vol.275 , pp. 29955-29959
    • Ryu, J.1    Pyo, H.2    Jou, I.3    Joe, E.4
  • 33
    • 0030984097 scopus 로고    scopus 로고
    • Inhibition of cytokine-induced inducible nitric oxide synthase expression by glucagon and cAMP in cultured hepatocytes
    • Smith FS, Ceppi ED, Titheradge M.A. Inhibition of cytokine-induced inducible nitric oxide synthase expression by glucagon and cAMP in cultured hepatocytes. Biochem J 1997;326:187-92
    • (1997) Biochem J , vol.326 , pp. 187-192
    • Smith, F.S.1    Ceppi, E.D.2    Titheradge, M.A.3
  • 38
    • 0022644493 scopus 로고
    • Immunocytochemical characterisation of the immune reaction in the central nervous system in multiple sclerosis. Possible role for microglia in lesion growth
    • Woodroofe MN, Bellamy AS, Feldmann M, Davison AN, Cuzner ML. Immunocytochemical characterisation of the immune reaction in the central nervous system in multiple sclerosis. Possible role for microglia in lesion growth. J Neurol Sci 1986;74:135-52
    • (1986) J Neurol Sci , vol.74 , pp. 135-152
    • Woodroofe, M.N.1    Bellamy, A.S.2    Feldmann, M.3    Davison, A.N.4    Cuzner, M.L.5
  • 39
    • 0027255749 scopus 로고
    • Promoter of the mouse gene encoding calcium-independent nitric oxide synthase confers inducibility by interferon gamma and bacterial lipopolysaccharide
    • Xie QW, Whisnant R, Nathan C. Promoter of the mouse gene encoding calcium-independent nitric oxide synthase confers inducibility by interferon gamma and bacterial lipopolysaccharide. J Exp Med 1993;177:1779-84
    • (1993) J Exp Med , vol.177 , pp. 1779-1784
    • Xie, Q.W.1    Whisnant, R.2    Nathan, C.3
  • 41
    • 0026554225 scopus 로고
    • Production of nitrite by neonatal rat microglial cells/brain macrophages
    • Zielasek J, Tausch M, Toyka KV, Hartung HP. Production of nitrite by neonatal rat microglial cells/brain macrophages. Cell Immunol 1992;141:111-20
    • (1992) Cell Immunol , vol.141 , pp. 111-120
    • Zielasek, J.1    Tausch, M.2    Toyka, K.V.3    Hartung, H.P.4


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