Modulation of the cell cycle and induction of apoptosis in human cancer cells by synthetic bile acids

Current Cancer Drug Targets

Volumn 6, Issue 8, 2006, Pages 681-689

  Nam, Deuk Kim ^a   Im, Eunok ^a,d   Young, Hyun Yoo ^b   Yung, Hyun Choi ^c  

^a Pusan National University   (South Korea)

^b Dong A University College of Medicine   (South Korea)

^c Dong Eui University   (South Korea)

^d SCHEPENS EYE RESEARCH INSTITUTE   (United States)

Author keywords

Apoptosis; Bile acids; Cell cycle; Synthetic bile acid derivatives

Indexed keywords

BILE ACID; CARVEDILOL; CASPASE; CHENODEOXYCHOLIC ACID; CHENODEOXYCHOLIC ACID DERIVATIVE; CYCLIN DEPENDENT KINASE INHIBITOR 1; DEOXYCHOLIC ACID; DOXORUBICIN; GLYCOCHENODEOXYCHOLIC ACID; GLYCODEOXYCHOLIC ACID; LITHOCHOLIC ACID; PROTEIN BAX; PROTEIN P53; STRESS ACTIVATED PROTEIN KINASE; TAUROCHENODEOXYCHOLIC ACID; URSODEOXYCHOLIC ACID;

APOPTOSIS; BILE SECRETION; BIOLOGICAL ACTIVITY; BREAST CANCER; CANCER CELL; CELL CYCLE; CELL CYCLE ARREST; CONCENTRATION RESPONSE; DRUG STRUCTURE; ENZYME ACTIVATION; GROWTH INHIBITION; HOMEOSTASIS; HUMAN; LEUKEMIA CELL LINE; LIVER CELL; NONHUMAN; PATHOPHYSIOLOGY; PROSTATE CANCER; REVIEW; T CELL LEUKEMIA; TUMOR SUPPRESSOR GENE; TUMOR VOLUME; UPREGULATION;

APOPTOSIS; BILE ACIDS AND SALTS; CELL CYCLE; HUMANS; MITOCHONDRIA; NEOPLASMS;

EID: 33845298932     PISSN: 15680096     EISSN: None     Source Type: Journal    
DOI: 10.2174/156800906779010236     Document Type: Review

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