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Volumn 71, Issue 6, 1997, Pages 959-965

The baxα:Bcl-2 ratio modulates the response to dexamethasone in leukaemic cells and is highly variable in childhood acute leukemia

Author keywords

[No Author keywords available]

Indexed keywords

DEXAMETHASONE; PROTEIN BAX; PROTEIN BCL 2; THAPSIGARGIN;

EID: 0030982224     PISSN: 00207136     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-0215(19970611)71:6<959::AID-IJC9>3.0.CO;2-X     Document Type: Article
Times cited : (124)

References (23)
  • 1
    • 0029669929 scopus 로고    scopus 로고
    • T cells from baxα transgenic mice show accelerated apoptosis in response to stimuli but do not show restored DNA-damage-induced cell death in the absence of p53
    • BRADY, H.J.M., SALOMONS, O.S., BOBELDIJK, R.C. and BERNS, A.J.M., T cells from baxα transgenic mice show accelerated apoptosis in response to stimuli but do not show restored DNA-damage-induced cell death in the absence of p53. EMBO J., 15, 1221-1230 (1996).
    • (1996) EMBO J , vol.15 , pp. 1221-1230
    • Brady, H.J.M.1    Salomons, O.S.2    Bobeldijk, R.C.3    Berns, A.J.M.4
  • 3
    • 0027164144 scopus 로고
    • High expression of bcl-2 protein in acute myeloid leukemia cells is associated with poor response to chemotherapy
    • CAMPOS, L., ROUAULT, J.P., SABIDO, O., ORIOL, P., ROUBI, N., VASSELON, C., ARCHIMBAUD, E., MAGAUD, J.P. and GUYOTAT, D., High expression of bcl-2 protein in acute myeloid leukemia cells is associated with poor response to chemotherapy. Blood, 81, 3091-3096 (1993).
    • (1993) Blood , vol.81 , pp. 3091-3096
    • Campos, L.1    Rouault, J.P.2    Sabido, O.3    Oriol, P.4    Roubi, N.5    Vasselon, C.6    Archimbaud, E.7    Magaud, J.P.8    Guyotat, D.9
  • 5
    • 0030584079 scopus 로고    scopus 로고
    • Apoptosis meets signal transduction: Elimination of BAD influence
    • GAJEWSKI, T.F. and THOMPSON, C.B., Apoptosis meets signal transduction: elimination of BAD influence. Cell, 87, 589-592 (1996).
    • (1996) Cell , vol.87 , pp. 589-592
    • Gajewski, T.F.1    Thompson, C.B.2
  • 6
    • 0028145136 scopus 로고
    • High expression of bcl-2 is the rule in acute lymphoblastic leukemia, except in Burkitt sub-type at presentation, and is not correlated with the prognosis
    • GALA, J.L., VERMYLEN, C., CORNU, G., FERRANT, A., MICHAUX, J.L., PHILIPPE, M. and MARTIAT, P., High expression of bcl-2 is the rule in acute lymphoblastic leukemia, except in Burkitt sub-type at presentation, and is not correlated with the prognosis. Ann. Hematol., 69, 17-24 (1994).
    • (1994) Ann. Hematol. , vol.69 , pp. 17-24
    • Gala, J.L.1    Vermylen, C.2    Cornu, G.3    Ferrant, A.4    Michaux, J.L.5    Philippe, M.6    Martiat, P.7
  • 8
    • 0030020462 scopus 로고    scopus 로고
    • High incidence of potential p53 inactivation in poor-outcome childhood acute lymphoblastic leukemia at diagnosis
    • MARKS, D.I., KURZ, B.W., LINK, M.P., NG, E., SHUSTER, J.J., LAUER, S.J., BRODSKY, I. and HAINES, D.S., High incidence of potential p53 inactivation in poor-outcome childhood acute lymphoblastic leukemia at diagnosis. Blood, 87, 1155-1161 (1996).
    • (1996) Blood , vol.87 , pp. 1155-1161
    • Marks, D.I.1    Kurz, B.W.2    Link, M.P.3    Ng, E.4    Shuster, J.J.5    Lauer, S.J.6    Brodsky, I.7    Haines, D.S.8
  • 10
    • 0028883179 scopus 로고
    • Tumor suppressor p53 is a direct transcriptional activator of the human box gene
    • MIYASHITA, T. and RUED, J.C., Tumor suppressor p53 is a direct transcriptional activator of the human box gene. Cell, 80, 293-299 (1995).
    • (1995) Cell , vol.80 , pp. 293-299
    • Miyashita, T.1    Rued, J.C.2
  • 11
    • 0026781986 scopus 로고
    • Bcl-2 gene transfer increases relative resistance of S49.1 and WEHI7.2 lymphoid cells to cell death and DNA fragmentation induced by glucocorticoids and multiple chemotherapeutic drugs
    • MIYASHITA, T. and REED, J.C., bcl-2 gene transfer increases relative resistance of S49.1 and WEHI7.2 lymphoid cells to cell death and DNA fragmentation induced by glucocorticoids and multiple chemotherapeutic drugs. Cancer Res., 52, 5407-5411 (1992).
    • (1992) Cancer Res. , vol.52 , pp. 5407-5411
    • Miyashita, T.1    Reed, J.C.2
  • 12
    • 0027166048 scopus 로고
    • Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax. that accelerates programmed cell death
    • OLTVAI, Z., MILLIMAN, C. and KORSMEYER, S.J., Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax. that accelerates programmed cell death. Cell. 74, 609-619 (1993).
    • (1993) Cell. , vol.74 , pp. 609-619
    • Oltvai, Z.1    Milliman, C.2    Korsmeyer, S.J.3
  • 13
    • 0029156492 scopus 로고
    • Primitive human hematopoietic precursors express Bcl-x but not Bcl-2
    • PARK, J.R., BERNSTEIN, I.D. and HOCKENBERY, D.M., Primitive human hematopoietic precursors express Bcl-x but not Bcl-2. Blood. 86, 868-876 (1995).
    • (1995) Blood. , vol.86 , pp. 868-876
    • Park, J.R.1    Bernstein, I.D.2    Hockenbery, D.M.3
  • 15
    • 0025341687 scopus 로고
    • Expression of the bcl-2 oncogene protein is not specific for the 14;18 chromosomal translocation
    • PEZZELLA, F., TSE, A.G., CORDELL, J.L., PULFORD, K.A., GATTER, K.C. and MASON, D.Y., Expression of the bcl-2 oncogene protein is not specific for the 14;18 chromosomal translocation. Amer. J. Pathol., 137, 225-232 (1990).
    • (1990) Amer. J. Pathol. , vol.137 , pp. 225-232
    • Pezzella, F.1    Tse, A.G.2    Cordell, J.L.3    Pulford, K.A.4    Gatter, K.C.5    Mason, D.Y.6
  • 17
    • 0028958030 scopus 로고
    • Bcl-2: Prevention of apoptosis as a mechanism of drug resistance
    • REED, J.C., Bcl-2: prevention of apoptosis as a mechanism of drug resistance. Hematol. Oncol. Clin. North Amer., 9, 451-473 (1995).
    • (1995) Hematol. Oncol. Clin. North Amer. , vol.9 , pp. 451-473
    • Reed, J.C.1
  • 18
    • 0025751550 scopus 로고
    • Bcl-2 inhibits multiple forms of apoptosis but not negative selection in thymocytes
    • SENTMAN, C.L., SHUTTER, J.R., HOCKENBERY, D., KANAGAWA, O. and KORSMEYER, S.J., bcl-2 inhibits multiple forms of apoptosis but not negative selection in thymocytes. Cell, 67, 879-888 (1991).
    • (1991) Cell , vol.67 , pp. 879-888
    • Sentman, C.L.1    Shutter, J.R.2    Hockenbery, D.3    Kanagawa, O.4    Korsmeyer, S.J.5
  • 19
    • 0028865264 scopus 로고
    • Prognostic value of bcl-2 oncoprotein in stage-II colon carcinoma
    • SINICROPE, F.A., HART, J., MICHELASSI, F. and LEE, J.J., Prognostic value of bcl-2 oncoprotein in stage-II colon carcinoma. Clin. Cancer Res., 1, 1103-1110 (1995).
    • (1995) Clin. Cancer Res. , vol.1 , pp. 1103-1110
    • Sinicrope, F.A.1    Hart, J.2    Michelassi, F.3    Lee, J.J.4
  • 20
    • 0028787708 scopus 로고
    • DMA index and %S-phase cells determined in acute lymphoblastic leukemia of children: A report from studies ALL V, ALL VI, and ALL VII (1979-1991) of the Dutch Childhood Leukemia Study Group and the Netherlands Workgroup on Cancer Genetics and Cytogenetics
    • SMETS, L.A., SLATER, R., VAN WERING, E.R., VAN DER DOES-VAN DEN BERG, A., HART, A.A., VEERMAN, A.J. and KAMPS, W.A., DMA index and %S-phase cells determined in acute lymphoblastic leukemia of children: a report from studies ALL V, ALL VI, and ALL VII (1979-1991) of the Dutch Childhood Leukemia Study Group and The Netherlands Workgroup on Cancer Genetics and Cytogenetics. Med Pediatr. Oncol., 25, 437-444 (1995).
    • (1995) Med Pediatr. Oncol. , vol.25 , pp. 437-444
    • Smets, L.A.1    Slater, R.2    Van Wering, E.R.3    Van der Does-van den Berg, A.4    Hart, A.A.5    Veerman, A.J.6    Kamps, W.A.7
  • 21
    • 0028085750 scopus 로고
    • BCL-2 expression and mitochondrial activity in leukemic cells with different sensitivity to glucocorticoid-induced apoptosis
    • SMETS, L.A., VAN DEN BERG, J., ACTON, D., TOP, B., VAN ROOIJ, H. and VERWIJS-JANSSEN, M., BCL-2 expression and mitochondrial activity in leukemic cells with different sensitivity to glucocorticoid-induced apoptosis. Blood, 84, 1613-1619 (1994).
    • (1994) Blood , vol.84 , pp. 1613-1619
    • Smets, L.A.1    Van Den Berg, J.2    Acton, D.3    Top, B.4    Van Rooij, H.5    Verwijs-Janssen, M.6
  • 22
    • 0029846602 scopus 로고    scopus 로고
    • Association of bcl-2. bax, bcl-xL and interleukin-1 beta-converting enzyme expression with initial response to chemotherapy in acute myeloid leukemia
    • STOETZER, O.J., NUSSLER, V., DARSOW, M., GULLIS, E., PELKA-FLEISCHER, R., SCHEEL, U. and WILMANNS, W., Association of bcl-2. bax, bcl-xL and interleukin-1 beta-converting enzyme expression with initial response to chemotherapy in acute myeloid leukemia. Leukemia, 10(Suppl. 3), S18-S22 (1996).
    • (1996) Leukemia , vol.10 , Issue.SUPPL. 3
    • Stoetzer, O.J.1    Nussler, V.2    Darsow, M.3    Gullis, E.4    Pelka-Fleischer, R.5    Scheel, U.6    Wilmanns, W.7
  • 23
    • 0029978058 scopus 로고    scopus 로고
    • Drug-induced apoptosis in B-cell chronic lymphocytic leukemia: Relationship between p53-gene mutation and bcl-2/bax proteins in drug resistance
    • THOMAS, A., EL ROUBY, S., REED, J.C., KRAJEWSKI, S., SILBER, R., POTMESIL, M. and NEWCOMB, E.W., Drug-induced apoptosis in B-cell chronic lymphocytic leukemia: relationship between p53-gene mutation and bcl-2/bax proteins in drug resistance. Oncogene, 12, 1055-1062 (1996).
    • (1996) Oncogene , vol.12 , pp. 1055-1062
    • Thomas, A.1    El Rouby, S.2    Reed, J.C.3    Krajewski, S.4    Silber, R.5    Potmesil, M.6    Newcomb, E.W.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.