-
1
-
-
0032919402
-
Toxic bile salts induce rodent hepatocyte apoptosis via direct activation of Fas
-
W.A. Faubion, M.E. Guicciardi, H. Meyoshi, S.F. Bronk, P.J. Roberts, P.A. Svingen, S.H. Kaufmann, G.J. Gores Toxic bile salts induce rodent hepatocyte apoptosis via direct activation of Fas J Clin Invest 103 1999 137 145
-
(1999)
J Clin Invest
, vol.103
, pp. 137-145
-
-
Faubion, W.A.1
Guicciardi, M.E.2
Meyoshi, H.3
Bronk, S.F.4
Roberts, P.J.5
Svingen, P.A.6
Kaufmann, S.H.7
Gores, G.J.8
-
2
-
-
0030906632
-
Bile salt-induced apoptosis of hepatocytes involves activation of protein kinase C
-
B.A. Jones, Y.P. Rao, R.T. Stravitz, G.J. Gores Bile salt-induced apoptosis of hepatocytes involves activation of protein kinase C Am J Physiol 272 1997 G1109 G1115
-
(1997)
Am J Physiol
, vol.272
-
-
Jones, B.A.1
Rao, Y.P.2
Stravitz, R.T.3
Gores, G.J.4
-
3
-
-
0032869839
-
Hepatocyte apoptosis after bile duct ligation in the mouse involves CD95
-
H. Miyoshi, C. Rust, P.J. Roberts, L.J. Burgart, G.J. Gores Hepatocyte apoptosis after bile duct ligation in the mouse involves CD95 Gastroenterology 117 1999 669 677
-
(1999)
Gastroenterology
, vol.117
, pp. 669-677
-
-
Miyoshi, H.1
Rust, C.2
Roberts, P.J.3
Burgart, L.J.4
Gores, G.J.5
-
4
-
-
0028135420
-
Increases of intracellular magnesium promote glycodeoxycholate-induced apoptosis in rat hepatocytes
-
T. Patel, S.F. Bronk, G.J. Gores Increases of intracellular magnesium promote glycodeoxycholate-induced apoptosis in rat hepatocytes J Clin Invest 94 1994 2183 2192
-
(1994)
J Clin Invest
, vol.94
, pp. 2183-2192
-
-
Patel, T.1
Bronk, S.F.2
Gores, G.J.3
-
5
-
-
0035129976
-
Bile acid induced rat hepatocyte apoptosis is inhibited by antioxidants and blockers of the mitochondrial permeability transition
-
B. Yerushalmi, R. Dahl, M.W. Devereaux, E. Gumpricht, R.J. Sokol Bile acid induced rat hepatocyte apoptosis is inhibited by antioxidants and blockers of the mitochondrial permeability transition Hepatology 33 2001 616 626
-
(2001)
Hepatology
, vol.33
, pp. 616-626
-
-
Yerushalmi, B.1
Dahl, R.2
Devereaux, M.W.3
Gumpricht, E.4
Sokol, R.J.5
-
6
-
-
0035014692
-
The bile acid-activated phosphatidylinositol 3-kinase pathway inhibits CD95 apoptosis upstream of bid in rodent hepatocytes
-
Y. Takikawa, H. Miyoshi, C. Rust, P. Roberts, R. Siegel, P.K. Mandal, R.E. Millikan, G.J. Gores The bile acid-activated phosphatidylinositol 3-kinase pathway inhibits CD95 apoptosis upstream of bid in rodent hepatocytes Gastroenterology 120 2001 1810 1817
-
(2001)
Gastroenterology
, vol.120
, pp. 1810-1817
-
-
Takikawa, Y.1
Miyoshi, H.2
Rust, C.3
Roberts, P.4
Siegel, R.5
Mandal, P.K.6
Millikan, R.E.7
Gores, G.J.8
-
7
-
-
0032525819
-
A novel role for ursodeoxycholic acid in inhibiting apoptosis by modulating mitochondrial membrane pertubation
-
C.M. Rodrigues, G. Fan, X. Ma, B.T. Kren, C.J. Steer A novel role for ursodeoxycholic acid in inhibiting apoptosis by modulating mitochondrial membrane pertubation J Clin Invest 101 1998 2790 2799
-
(1998)
J Clin Invest
, vol.101
, pp. 2790-2799
-
-
Rodrigues, C.M.1
Fan, G.2
Ma, X.3
Kren, B.T.4
Steer, C.J.5
-
8
-
-
0031422501
-
Apoptosis induced in rat hepatocytes by in vivo exposure to taurochenodeoxycholate
-
P. Chieco, E. Romagnoli, G. Aicardi, A. Suozzi, G.C. Forti, A. Roda Apoptosis induced in rat hepatocytes by in vivo exposure to taurochenodeoxycholate Histochem J 29 1997 875 883
-
(1997)
Histochem J
, vol.29
, pp. 875-883
-
-
Chieco, P.1
Romagnoli, E.2
Aicardi, G.3
Suozzi, A.4
Forti, G.C.5
Roda, A.6
-
9
-
-
0036708291
-
Death-receptor-mediated apoptosis and the liver
-
J.H. Yoon, G.J. Gores Death-receptor-mediated apoptosis and the liver J Hepatol 37 2002 400 410
-
(2002)
J Hepatol
, vol.37
, pp. 400-410
-
-
Yoon, J.H.1
Gores, G.J.2
-
10
-
-
0033936183
-
Bile salts mediate hepatocyte apoptosis by increasing cell surface trafficking of CD95
-
T. Sodeman, S.F. Bronk, P.J. Roberts, H. Miyoshi, G.J. Gores Bile salts mediate hepatocyte apoptosis by increasing cell surface trafficking of CD95 Am J Physiol Gastrointest Liver Physiol 278 2000 G992 G999
-
(2000)
Am J Physiol Gastrointest Liver Physiol
, vol.278
-
-
Sodeman, T.1
Bronk, S.F.2
Roberts, P.J.3
Miyoshi, H.4
Gores, G.J.5
-
11
-
-
0008290616
-
Diverse functions of JNK signaling and c-Jun in stress response and apoptosis
-
S. Leppa, D. Bohmann Diverse functions of JNK signaling and c-Jun in stress response and apoptosis Oncogene 18 1999 6158 6162
-
(1999)
Oncogene
, vol.18
, pp. 6158-6162
-
-
Leppa, S.1
Bohmann, D.2
-
12
-
-
0036241214
-
Taurolithocholic acid-3 sulfate induces CD95 trafficking and apoptosis in a c-Jun N-terminal kinase dependent manner
-
D. Graf, A.K. Kurz, R. Fischer, R. Reinehr, D. Häussinger Taurolithocholic acid-3 sulfate induces CD95 trafficking and apoptosis in a c-Jun N-terminal kinase dependent manner Gastroenterology 122 2002 1411 1427
-
(2002)
Gastroenterology
, vol.122
, pp. 1411-1427
-
-
Graf, D.1
Kurz, A.K.2
Fischer, R.3
Reinehr, R.4
Häussinger, D.5
-
13
-
-
0030862412
-
Cathepsin B contributes to bile salt-induced apoptosis of rat hepatocytes
-
L.R. Roberts, H. Kurosawa, S.F. Bronk, P.J. Fesmier, L.B. Agellon, W.Y. Leung, F. Mao, G.J. Gores Cathepsin B contributes to bile salt-induced apoptosis of rat hepatocytes Gastroenterology 113 1997 1714 1726
-
(1997)
Gastroenterology
, vol.113
, pp. 1714-1726
-
-
Roberts, L.R.1
Kurosawa, H.2
Bronk, S.F.3
Fesmier, P.J.4
Agellon, L.B.5
Leung, W.Y.6
Mao, F.7
Gores, G.J.8
-
14
-
-
0034108869
-
The NAD+ precursors, nicotinic acid and nicotinamide protect cells against apoptosis induced by a multiple stress inducer, deoxycholate
-
C.L. Crowley, C.M. Payne, H. Bernstein, C. Bernstein, D. Roe The NAD+ precursors, nicotinic acid and nicotinamide protect cells against apoptosis induced by a multiple stress inducer, deoxycholate Cell Death Differ 7 2000 314 326
-
(2000)
Cell Death Differ
, vol.7
, pp. 314-326
-
-
Crowley, C.L.1
Payne, C.M.2
Bernstein, H.3
Bernstein, C.4
Roe, D.5
-
15
-
-
0029123537
-
Generation of hydroperoxides in isolated rat hepatocytes and hepatic mitochondria exposed to hydrophobic bile acids
-
R.J. Sokol, B.M. Winkelhofer-Roob, M.W. Devereaux, J.M. McKim Generation of hydroperoxides in isolated rat hepatocytes and hepatic mitochondria exposed to hydrophobic bile acids Gastroenterology 109 1995 1249 1256
-
(1995)
Gastroenterology
, vol.109
, pp. 1249-1256
-
-
Sokol, R.J.1
Winkelhofer-Roob, B.M.2
Devereaux, M.W.3
McKim, J.M.4
-
16
-
-
0031983188
-
Vitamin e reduces oxidant injury to mitochondria and the hepatotoxicity of taurochenodeoxycholic acid in the rat
-
R.J. Sokol, J.M. McKim, M.C. Goff, S.Z. Ruyle, M.W. Devereaux, D. Han, L. Packer, G. Everson Vitamin E reduces oxidant injury to mitochondria and the hepatotoxicity of taurochenodeoxycholic acid in the rat Gastroenterology 1998 164 174
-
(1998)
Gastroenterology
, pp. 164-174
-
-
Sokol, R.J.1
McKim, J.M.2
Goff, M.C.3
Ruyle, S.Z.4
Devereaux, M.W.5
Han, D.6
Packer, L.7
Everson, G.8
-
17
-
-
0028091169
-
Toxicity of bile acids on the electron transport chain of isolated liver mitochondria
-
S. Krähenbühl, C. Talos, S. Fischer, J. Reichen Toxicity of bile acids on the electron transport chain of isolated liver mitochondria Hepatology 19 1994 471 479
-
(1994)
Hepatology
, vol.19
, pp. 471-479
-
-
Krähenbühl, S.1
Talos, C.2
Fischer, S.3
Reichen, J.4
-
18
-
-
0041322990
-
Bile salt-induced hepatocyte apoptosis involves epidermal growth factor receptor-dependent CD95 tyrosine phosphorylation
-
R. Reinehr, D. Graf, D. Häussinger Bile salt-induced hepatocyte apoptosis involves epidermal growth factor receptor-dependent CD95 tyrosine phosphorylation Gastroenterology 125 2003 839 853
-
(2003)
Gastroenterology
, vol.125
, pp. 839-853
-
-
Reinehr, R.1
Graf, D.2
Häussinger, D.3
-
19
-
-
0037389392
-
Hyperosmolarity and CD95L trigger CD95/EGF receptor association and tyrosine phosphorylation of CD95 as prerequisites for CD95 membrane trafficking and DISC formation
-
R. Reinehr, F. Schliess, D. Häussinger Hyperosmolarity and CD95L trigger CD95/EGF receptor association and tyrosine phosphorylation of CD95 as prerequisites for CD95 membrane trafficking and DISC formation FASEB J 17 2003 731 733
-
(2003)
FASEB J
, vol.17
, pp. 731-733
-
-
Reinehr, R.1
Schliess, F.2
Häussinger, D.3
-
20
-
-
0347361545
-
Inhibition of bile salt-induced apoptosis by cyclic AMP involves serine/threonine phosphorylation of CD95
-
R. Reinehr, D. Häussinger Inhibition of bile salt-induced apoptosis by cyclic AMP involves serine/threonine phosphorylation of CD95 Gastroenterology 126 2004 249 262
-
(2004)
Gastroenterology
, vol.126
, pp. 249-262
-
-
Reinehr, R.1
Häussinger, D.2
-
21
-
-
1642409200
-
CD95-tyrosine nitration inhibits hyperosmotic and CD95 ligand-induced CD95 activation in rat hepatocytes
-
R. Reinehr, B. Görg, A. Höngen, D. Häussinger CD95-tyrosine nitration inhibits hyperosmotic and CD95 ligand-induced CD95 activation in rat hepatocytes J Biol Chem 279 2004 10364 10373
-
(2004)
J Biol Chem
, vol.279
, pp. 10364-10373
-
-
Reinehr, R.1
Görg, B.2
Höngen, A.3
Häussinger, D.4
-
22
-
-
0038172651
-
Inhibition of taurolithocholate 3-sulfate-induced apoptosis by cyclic AMP in rat hepatocytes involves protein kinase a dependent and independent mechanisms
-
D. Graf, R. Reinehr, A.K. Kurz, R. Fischer, D. Häussinger Inhibition of taurolithocholate 3-sulfate-induced apoptosis by cyclic AMP in rat hepatocytes involves protein kinase A dependent and independent mechanisms Arch Biochem Biophys 415 2003 34 42
-
(2003)
Arch Biochem Biophys
, vol.415
, pp. 34-42
-
-
Graf, D.1
Reinehr, R.2
Kurz, A.K.3
Fischer, R.4
Häussinger, D.5
-
23
-
-
17344370605
-
Cyclic adenosine monophosphate-mediated protection against bile acid-induced apoptosis in cultured rat hepatocytes
-
C.R. Webster, M.S. Anwer Cyclic adenosine monophosphate-mediated protection against bile acid-induced apoptosis in cultured rat hepatocytes Hepatology 27 1998 1324 1331
-
(1998)
Hepatology
, vol.27
, pp. 1324-1331
-
-
Webster, C.R.1
Anwer, M.S.2
-
24
-
-
0036721290
-
CAMP inhibits bile acid-induced apoptosis by blocking caspase activation and cytochrome c release
-
C.R. Webster, P. Usechak, M.S. Anwer cAMP inhibits bile acid-induced apoptosis by blocking caspase activation and cytochrome c release Am J Physiol 238 2002 G727 G738
-
(2002)
Am J Physiol
, vol.238
-
-
Webster, C.R.1
Usechak, P.2
Anwer, M.S.3
-
25
-
-
0035976930
-
Cyclic AMP regulation of neutrophil apoptosis occurs via a novel protein kinase A-independent signaling pathway
-
M.C. Martin, C. Dransfield, A.G. Haslett, A.G. Rossi Cyclic AMP regulation of neutrophil apoptosis occurs via a novel protein kinase A-independent signaling pathway J Biol Chem 276 2001 45041 45050
-
(2001)
J Biol Chem
, vol.276
, pp. 45041-45050
-
-
Martin, M.C.1
Dransfield, C.2
Haslett, A.G.3
Rossi, A.G.4
-
26
-
-
0031439247
-
Cellular functions regulated by Src family kinases
-
S.M. Thomas, J.S. Brugge Cellular functions regulated by Src family kinases Annu Rev Cell Dev Biol 13 1997 513 609
-
(1997)
Annu Rev Cell Dev Biol
, vol.13
, pp. 513-609
-
-
Thomas, S.M.1
Brugge, J.S.2
-
27
-
-
0034693806
-
Selected glimpses into the activation and function of Src kinase
-
J.D. Bjorge, A. Jakymiw, D.J. Fujita Selected glimpses into the activation and function of Src kinase Oncogene 19 2000 5620 5635
-
(2000)
Oncogene
, vol.19
, pp. 5620-5635
-
-
Bjorge, J.D.1
Jakymiw, A.2
Fujita, D.J.3
-
28
-
-
0034697148
-
Src and Cas mediate JNK activation but not ERK1/2 and p38 kinases by reactive oxygen species
-
M. Yoshizumi, J. Abe, J. Haendeler, Q. Huang, B.C. Berk Src and Cas mediate JNK activation but not ERK1/2 and p38 kinases by reactive oxygen species J Biol Chem 275 2000 11706 11712
-
(2000)
J Biol Chem
, vol.275
, pp. 11706-11712
-
-
Yoshizumi, M.1
Abe, J.2
Haendeler, J.3
Huang, Q.4
Berk, B.C.5
-
29
-
-
0035860808
-
Activation of mitogen-activated protein kinase by membrane-targeted Raf chimeras is independent of raft localization
-
X. Chen, M.D. Resh Activation of mitogen-activated protein kinase by membrane-targeted Raf chimeras is independent of raft localization J Biol Chem 276 2001 34617 34623
-
(2001)
J Biol Chem
, vol.276
, pp. 34617-34623
-
-
Chen, X.1
Resh, M.D.2
-
30
-
-
0030761765
-
C-Src is required for oxidative stress-mediated activation of big mitogen-activated protein kinase 1
-
J. Abe, M. Takahashi, M. Ishida, J.D. Lee, B.C. Berk c-Src is required for oxidative stress-mediated activation of big mitogen-activated protein kinase 1 J Biol Chem 272 1997 20389 20394
-
(1997)
J Biol Chem
, vol.272
, pp. 20389-20394
-
-
Abe, J.1
Takahashi, M.2
Ishida, M.3
Lee, J.D.4
Berk, B.C.5
-
31
-
-
0034695441
-
Reactive oxygen species activate p90 ribosomal S6 kinase via Fyn and Ras
-
J. Abe, M. Okuda, Q. Huang, M. Yoshizumi, B.C. Berk Reactive oxygen species activate p90 ribosomal S6 kinase via Fyn and Ras J Biol Chem 275 2000 1739 1748
-
(2000)
J Biol Chem
, vol.275
, pp. 1739-1748
-
-
Abe, J.1
Okuda, M.2
Huang, Q.3
Yoshizumi, M.4
Berk, B.C.5
-
32
-
-
0037470136
-
Cholecystokinin stimulates extracellular signal-regulated kinase through activation of the epidermal growth factor receptor, Yes, and protein kinase C. Signal amplification at the level of Raf by activation of protein kinase Cepsilon
-
A. Piper, R. Elez, S.J. You, B. Kronenberger, S. Loitsch, S. Roche, S. Zeuzem Cholecystokinin stimulates extracellular signal-regulated kinase through activation of the epidermal growth factor receptor, Yes, and protein kinase C. Signal amplification at the level of Raf by activation of protein kinase Cepsilon J Biol Chem 278 2003 7065 7072
-
(2003)
J Biol Chem
, vol.278
, pp. 7065-7072
-
-
Piper, A.1
Elez, R.2
You, S.J.3
Kronenberger, B.4
Loitsch, S.5
Roche, S.6
Zeuzem, S.7
-
33
-
-
0034917954
-
Protein kinase C-dependent distribution of the multidrug resistance protein 2 from the canalicular to the basolateral membrane in human HepG2 cells
-
R. Kubitz, C. Huth, M. Schmitt, A. Horbach, G. Kullak-Ublick, D. Häussinger Protein kinase C-dependent distribution of the multidrug resistance protein 2 from the canalicular to the basolateral membrane in human HepG2 cells Hepatology 34 2001 340 350
-
(2001)
Hepatology
, vol.34
, pp. 340-350
-
-
Kubitz, R.1
Huth, C.2
Schmitt, M.3
Horbach, A.4
Kullak-Ublick, G.5
Häussinger, D.6
-
34
-
-
0025296058
-
PDGF-induced activation of phospholipase C is not required for induction of DNA synthesis
-
T.D. Hill, N. Dean, L.J. Mordan, A.F. Lau, M.Y. Kanemitsu, A.L. Boyton PDGF-induced activation of phospholipase C is not required for induction of DNA synthesis Science 248 1990 1660 1663
-
(1990)
Science
, vol.248
, pp. 1660-1663
-
-
Hill, T.D.1
Dean, N.2
Mordan, L.J.3
Lau, A.F.4
Kanemitsu, M.Y.5
Boyton, A.L.6
-
35
-
-
0034458943
-
SU6656, a selective src family kinase inhibitor, used to probe growth factor signaling
-
R.A. Blake, M.A. Broome, X. Liu, J. Wu, M. Gishizky, L. Sun, S.A. Courtneidge SU6656, a selective src family kinase inhibitor, used to probe growth factor signaling Mol Cell Biol 20 2000 9018 9027
-
(2000)
Mol Cell Biol
, vol.20
, pp. 9018-9027
-
-
Blake, R.A.1
Broome, M.A.2
Liu, X.3
Wu, J.4
Gishizky, M.5
Sun, L.6
Courtneidge, S.A.7
-
36
-
-
0030029143
-
Discovery of a novel, potent, and Src family-selective tyrosine kinase inhibitor. Study of Lck- and FynT-dependent T cell activation
-
J.H. Hanke, J.P. Gardner, R.L. Dow, P.S. Changelian, W.H. Brissette, E.J. Weringer, B.A. Pollok, P.A. Connelly Discovery of a novel, potent, and Src family-selective tyrosine kinase inhibitor. Study of Lck- and FynT-dependent T cell activation J Biol Chem 271 1996 695 701
-
(1996)
J Biol Chem
, vol.271
, pp. 695-701
-
-
Hanke, J.H.1
Gardner, J.P.2
Dow, R.L.3
Changelian, P.S.4
Brissette, W.H.5
Weringer, E.J.6
Pollok, B.A.7
Connelly, P.A.8
-
37
-
-
0026003225
-
Specific inhibition of cytoplasmic protein tyrosine kinases by herbimycin a in vitro
-
H. Fukazawa, P.M. Li, C. Yamamoto, Y. Murakami, S. Mizuno, Y. Uehara Specific inhibition of cytoplasmic protein tyrosine kinases by herbimycin A in vitro Biochem Pharmacol 42 1991 1661 1671
-
(1991)
Biochem Pharmacol
, vol.42
, pp. 1661-1671
-
-
Fukazawa, H.1
Li, P.M.2
Yamamoto, C.3
Murakami, Y.4
Mizuno, S.5
Uehara, Y.6
-
38
-
-
0026625611
-
Emodin, a protein tyrosine kinase inhibitor from Polygonum cuspidatum
-
H. Jayasuriya, N.M. Koonchanok, R.L. Geahlen, J.L. McLaughlin, C.J. Chang Emodin, a protein tyrosine kinase inhibitor from Polygonum cuspidatum J Nat Prod 55 1992 696 698
-
(1992)
J Nat Prod
, vol.55
, pp. 696-698
-
-
Jayasuriya, H.1
Koonchanok, N.M.2
Geahlen, R.L.3
McLaughlin, J.L.4
Chang, C.J.5
-
39
-
-
0028968949
-
Tyrosine kinase inhibition: An approach to drug development
-
A. Levitzki, A. Gazit Tyrosine kinase inhibition an approach to drug development Science 267 1995 1782 1788
-
(1995)
Science
, vol.267
, pp. 1782-1788
-
-
Levitzki, A.1
Gazit, A.2
-
40
-
-
0035152487
-
Cell-permeable peptide inhibitors of JNK: Novel blockers of β-cell death
-
C. Bonny, A. Oberson, S. Negri, C. Sauser, D.F. Schorderet Cell-permeable peptide inhibitors of JNK novel blockers of β-cell death Diabetes 50 2001 70 82
-
(2001)
Diabetes
, vol.50
, pp. 70-82
-
-
Bonny, C.1
Oberson, A.2
Negri, S.3
Sauser, C.4
Schorderet, D.F.5
-
41
-
-
0027157640
-
Selective inhibition of protein kinase C isozymes by the indolocarbazole Gö6976
-
G. Martiny-Baron, M.G. Kazanietz, H. Mischak, P.M. Blumberg, G. Kochs, H. Hug, D. Marme, C. Schachtele Selective inhibition of protein kinase C isozymes by the indolocarbazole Gö6976 J Biol Chem 268 1993 9194 9197
-
(1993)
J Biol Chem
, vol.268
, pp. 9194-9197
-
-
Martiny-Baron, G.1
Kazanietz, M.G.2
Mischak, H.3
Blumberg, P.M.4
Kochs, G.5
Hug, H.6
Marme, D.7
Schachtele, C.8
-
42
-
-
0037163042
-
Epidermal growth factor receptor activation under oxidative stress fails to promote c-Cbl-mediated down-regulation
-
T. Ravid, C. Sweeny, P. Gee, K.L. Carraway, T. Goldkorn Epidermal growth factor receptor activation under oxidative stress fails to promote c-Cbl-mediated down-regulation J Biol Chem 277 2002 31214 31219
-
(2002)
J Biol Chem
, vol.277
, pp. 31214-31219
-
-
Ravid, T.1
Sweeny, C.2
Gee, P.3
Carraway, K.L.4
Goldkorn, T.5
-
44
-
-
0033558855
-
Modulation of the protein tyrosine kinase activity and autophosphorylation of the epidermal growth factor receptor by its juxtamembrane region
-
H.M. Poppleton, G.J. Wiepz, P.J. Bertics, T.B. Patel Modulation of the protein tyrosine kinase activity and autophosphorylation of the epidermal growth factor receptor by its juxtamembrane region Arch Biochem Biophys 363 1999 227 236
-
(1999)
Arch Biochem Biophys
, vol.363
, pp. 227-236
-
-
Poppleton, H.M.1
Wiepz, G.J.2
Bertics, P.J.3
Patel, T.B.4
-
45
-
-
0035088560
-
Cholestatic expression pattern of sinusoidal and canalicular organic anion transport systems in primary cultured rat hepatocytes
-
S.J. Rippin, B. Hagenbuch, P.J. Meier, B. Stieger Cholestatic expression pattern of sinusoidal and canalicular organic anion transport systems in primary cultured rat hepatocytes Hepatology 33 2001 776 782
-
(2001)
Hepatology
, vol.33
, pp. 776-782
-
-
Rippin, S.J.1
Hagenbuch, B.2
Meier, P.J.3
Stieger, B.4
-
46
-
-
0036238779
-
Transport of the sulfated, amidated bile acid, sulfolithocholyltaurine, into rat hepatocytes is mediated by Oatp1 and Oatp2
-
L.J. Meng, P. Wang, A.W. Wolkoff, R.B. Kim, R.G. Tirona, A.F. Hofmann, K.S. Pang Transport of the sulfated, amidated bile acid, sulfolithocholyltaurine, into rat hepatocytes is mediated by Oatp1 and Oatp2 Hepatology 35 2002 1031 1040
-
(2002)
Hepatology
, vol.35
, pp. 1031-1040
-
-
Meng, L.J.1
Wang, P.2
Wolkoff, A.W.3
Kim, R.B.4
Tirona, R.G.5
Hofmann, A.F.6
Pang, K.S.7
-
47
-
-
3042594002
-
Involvement of integrins and Src in tauroursodeoxycholate-induced and swelling-induced choleresis
-
D. Häussinger, A.K. Kurz, M. Wettstein, D. Graf, S. Vom Dahl, F. Schliess Involvement of integrins and Src in tauroursodeoxycholate-induced and swelling-induced choleresis Gastroenterology 124 2003 1476 1487
-
(2003)
Gastroenterology
, vol.124
, pp. 1476-1487
-
-
Häussinger, D.1
Kurz, A.K.2
Wettstein, M.3
Graf, D.4
Vom Dahl, S.5
Schliess, F.6
-
48
-
-
0029790979
-
Dephosphorylation of receptor tyrosine kinases as target of regulation by radiation, oxidants or alkylating agents
-
A. Knebel, H.J. Rahmsdorf, A. Ullrich, P. Herrlich Dephosphorylation of receptor tyrosine kinases as target of regulation by radiation, oxidants or alkylating agents EMBO J 15 1996 5314 5325
-
(1996)
EMBO J
, vol.15
, pp. 5314-5325
-
-
Knebel, A.1
Rahmsdorf, H.J.2
Ullrich, A.3
Herrlich, P.4
-
49
-
-
0141755338
-
Epidermal growth factor receptor is a common mediator of quinone-induced signaling leading to phosphorylation of connexin-43: Role of glutathione and tyrosine phosphatases
-
K. Abdelmohsen, P.A. Gerber, C. von Montfort, H. Sies, L.O. Klotz Epidermal growth factor receptor is a common mediator of quinone-induced signaling leading to phosphorylation of connexin-43 role of glutathione and tyrosine phosphatases J Biol Chem 278 2003 38360 38367
-
(2003)
J Biol Chem
, vol.278
, pp. 38360-38367
-
-
Abdelmohsen, K.1
Gerber, P.A.2
Von Montfort, C.3
Sies, H.4
Klotz, L.O.5
-
50
-
-
0032529391
-
Regulation of tyrosine phosphorylation in isolated T cell membrane by inhibition of protein tyrosine phosphatases
-
Y.J. Jin, J. Friedman, S.J. Burakoff Regulation of tyrosine phosphorylation in isolated T cell membrane by inhibition of protein tyrosine phosphatases J Immunol 161 1998 1743 1750
-
(1998)
J Immunol
, vol.161
, pp. 1743-1750
-
-
Jin, Y.J.1
Friedman, J.2
Burakoff, S.J.3
-
51
-
-
0035167269
-
Deoxycholic acid (DCA) causes ligand-independent activation of epidermal growth factor receptor (EGFR) and Fas receptor in primary hepatocytes: Inhibition of EGFR/mitogen-activated protein kinase-signaling module enhances DCA-induced apoptosis
-
L. Qiao, E. Studer, K. Leach, R. McKinstry, S. Gupta, R. Decker, R. Kukreja, K. Valerie, P. Nagarkatti, W.E. Deiry, J. Molkentin, R. Schmidt-Ullrich, P.B. Fisher, S. Grant, P.B. Hylemon, P. Dent Deoxycholic acid (DCA) causes ligand-independent activation of epidermal growth factor receptor (EGFR) and Fas receptor in primary hepatocytes inhibition of EGFR/mitogen-activated protein kinase-signaling module enhances DCA-induced apoptosis Mol Biol Cell 12 2001 2609 2645
-
(2001)
Mol Biol Cell
, vol.12
, pp. 2609-2645
-
-
Qiao, L.1
Studer, E.2
Leach, K.3
McKinstry, R.4
Gupta, S.5
Decker, R.6
Kukreja, R.7
Valerie, K.8
Nagarkatti, P.9
Deiry, W.E.10
Molkentin, J.11
Schmidt-Ullrich, R.12
Fisher, P.B.13
Grant, S.14
Hylemon, P.B.15
Dent, P.16
-
52
-
-
2642584894
-
The Src-family kinase Yes triggers hyperosmotic activation of the epidermal growth factor receptor and CD95
-
R. Reinehr, S. Becker, A. Höngen, D. Häussinger The Src-family kinase Yes triggers hyperosmotic activation of the epidermal growth factor receptor and CD95 J Biol Chem 279 2004 23977 23987
-
(2004)
J Biol Chem
, vol.279
, pp. 23977-23987
-
-
Reinehr, R.1
Becker, S.2
Höngen, A.3
Häussinger, D.4
-
53
-
-
0032217156
-
C-Cbl/Sli-1 regulates endocytic sorting and ubiquitination of the epidermal growth factor receptor
-
G. Levkowitz, H. Waterman, E. Zamir, Z. Kam, S. Oved, W.Y. Langdon, L. Beguinot, B. Geiger, Y. Yarden c-Cbl/Sli-1 regulates endocytic sorting and ubiquitination of the epidermal growth factor receptor Genes Dev 12 1998 3663 3674
-
(1998)
Genes Dev
, vol.12
, pp. 3663-3674
-
-
Levkowitz, G.1
Waterman, H.2
Zamir, E.3
Kam, Z.4
Oved, S.5
Langdon, W.Y.6
Beguinot, L.7
Geiger, B.8
Yarden, Y.9
-
54
-
-
0034949705
-
C-Cbl ubiquitinates the EGF receptor at the plasma membrane and remains receptor associated throughout the endocytic route
-
A.A. de Melker, G. van der Horst, J. Calafat, H. Jansen, J. Borst c-Cbl ubiquitinates the EGF receptor at the plasma membrane and remains receptor associated throughout the endocytic route J Cell Sci 114 2001 2167 2178
-
(2001)
J Cell Sci
, vol.114
, pp. 2167-2178
-
-
De Melker, A.A.1
Van Der Horst, G.2
Calafat, J.3
Jansen, H.4
Borst, J.5
-
55
-
-
0037075547
-
Cbl-CIN85-endophilin complex mediates ligand-induced downregulation of EGF receptors
-
P. Soubeyran, K. Kowanetz, I. Szymkiewicz, W.Y. Langdon, I. Dikic Cbl-CIN85-endophilin complex mediates ligand-induced downregulation of EGF receptors Nature 416 2002 183 187
-
(2002)
Nature
, vol.416
, pp. 183-187
-
-
Soubeyran, P.1
Kowanetz, K.2
Szymkiewicz, I.3
Langdon, W.Y.4
Dikic, I.5
-
56
-
-
0033628016
-
Kinases of the Src Family: Structure and functions
-
A.G. Tatosyan, O.A. Mizenina Kinases of the Src Family structure and functions Biochemistry (Moscow) 65 2000 57 67
-
(2000)
Biochemistry (Moscow)
, vol.65
, pp. 57-67
-
-
Tatosyan, A.G.1
Mizenina, O.A.2
-
57
-
-
0029896163
-
Regulation, substrates and functions of src
-
M.T. Brown, J.A. Cooper Regulation, substrates and functions of src Biochim Biophys Acta 1287 1996 121 149
-
(1996)
Biochim Biophys Acta
, vol.1287
, pp. 121-149
-
-
Brown, M.T.1
Cooper, J.A.2
-
58
-
-
0027337969
-
c-src from the membrane to the cytosol after stimulation by platelet-derived growth factor
-
c-src from the membrane to the cytosol after stimulation by platelet-derived growth factor J Biol Chem 268 1993 19552 19558
-
(1993)
J Biol Chem
, vol.268
, pp. 19552-19558
-
-
Walker, F.1
De Blaquiere, J.2
Burgess, A.W.3
-
59
-
-
0030614911
-
Gβγ subunits mediate Src-dependent phosphorylation of the epidermal growth factor receptor
-
L.M. Luttrell, G.J. Della Rocca, T. van Biesen, D.K. Luttrell, R.J. Lefkowitz Gβγ subunits mediate Src-dependent phosphorylation of the epidermal growth factor receptor J Biol Chem 272 1997 4637 4644
-
(1997)
J Biol Chem
, vol.272
, pp. 4637-4644
-
-
Luttrell, L.M.1
Della Rocca, G.J.2
Van Biesen, T.3
Luttrell, D.K.4
Lefkowitz, R.J.5
-
60
-
-
0034992521
-
The epidermal growth factor receptor family as a central element for cellular signal transduction and diversification
-
N. Prenzel, O.M. Fischer, S. Streit, S. Hart, A. Ullrich The epidermal growth factor receptor family as a central element for cellular signal transduction and diversification Endocr Relat Cancer 8 2001 11 31
-
(2001)
Endocr Relat Cancer
, vol.8
, pp. 11-31
-
-
Prenzel, N.1
Fischer, O.M.2
Streit, S.3
Hart, S.4
Ullrich, A.5
-
62
-
-
0035844273
-
C-Jun-N-terminal kinase activation by hydrogen peroxide in endothelial cells involves Src-dependent epidermal growth factor receptor transactivation
-
K. Chen, J.A. Vita, B.C. Berk, J.F. Keaney Jr c-Jun-N-terminal kinase activation by hydrogen peroxide in endothelial cells involves Src-dependent epidermal growth factor receptor transactivation J Biol Chem 276 2001 16045 16050
-
(2001)
J Biol Chem
, vol.276
, pp. 16045-16050
-
-
Chen, K.1
Vita, J.A.2
Berk, B.C.3
Keaney Jr., J.F.4
-
63
-
-
0037016706
-
Activation of extracellular signal-regulated kinase by ultraviolet is mediated through Src-dependent epidermal growth factor receptor phosphorylation. Its implication in an anti-apoptotic function
-
D. Kitagawa, S. Tanemura, S. Ohata, N. Shimizu, J. Seo, G. Nishitai, T. Watanabe, K. Nakagawa, H. Kishimoto, T. Wada, T. Tezuka, T. Yamamoto, H. Nishina, T. Katada Activation of extracellular signal-regulated kinase by ultraviolet is mediated through Src-dependent epidermal growth factor receptor phosphorylation. Its implication in an anti-apoptotic function J Biol Chem 277 2002 366 371
-
(2002)
J Biol Chem
, vol.277
, pp. 366-371
-
-
Kitagawa, D.1
Tanemura, S.2
Ohata, S.3
Shimizu, N.4
Seo, J.5
Nishitai, G.6
Watanabe, T.7
Nakagawa, K.8
Kishimoto, H.9
Wada, T.10
Tezuka, T.11
Yamamoto, T.12
Nishina, H.13
Katada, T.14
-
64
-
-
0037483090
-
The SH4-unique-Sh3-SH2 domains dictate specificity in signaling that differentiate c-Yes from c-Src
-
J.M. Summy, Y. Qian, B.H. Jiang, A. Guappone-Koay, A. Gatesman, X. Shi, D.C. Flynn The SH4-unique-Sh3-SH2 domains dictate specificity in signaling that differentiate c-Yes from c-Src J Cell Sci 116 2003 2585 2598
-
(2003)
J Cell Sci
, vol.116
, pp. 2585-2598
-
-
Summy, J.M.1
Qian, Y.2
Jiang, B.H.3
Guappone-Koay, A.4
Gatesman, A.5
Shi, X.6
Flynn, D.C.7
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