Sustained exposure to high glucose concentrations modifies glucose signaling and the mechanics of secretory vesicle fusion in primary rat pancreatic β-cells

Diabetes

Volumn 55, Issue 4, 2006, Pages 1057-1065

  Tsuboi, Takashi ^a   Ravier, Magalie A ^a   Parton, Laura E ^a   Rutter, Guy A ^a  

^a UNIVERSITY OF BRISTOL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

GLUCOKINASE; GLUCOSE; GLUCOSE TRANSPORTER 2; GREEN FLUORESCENT PROTEIN; NEUROPEPTIDE Y; POTASSIUM CHLORIDE; RED FLUORESCENT PROTEIN; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; YELLOW FLUORESCENT PROTEIN; CALCIUM; INSULIN; PREPROINSULIN; PRIMER DNA; PROINSULIN; PROTEIN PRECURSOR; SYNAPTOTAGMIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CALCIUM CELL LEVEL; CALCIUM TRANSPORT; CONTROLLED STUDY; EXOCYTOSIS; FLUORESCENCE MICROSCOPY; GENE EXPRESSION; GLUCOSE BLOOD LEVEL; HYPERGLYCEMIA; INSULIN RELEASE; INSULINOMA; MALE; MOLECULAR PROBE; NANOTECHNOLOGY; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; RAT; SIGNAL TRANSDUCTION; ANIMAL; CELL CULTURE; CELL LINE; CONFOCAL MICROSCOPY; DRUG EFFECT; GENETICS; METABOLISM; PANCREAS ISLET; PH; PHYSIOLOGY; REPORTER GENE; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SECRETION;

ANIMALS; CALCIUM; CELL LINE; CELLS, CULTURED; DNA PRIMERS; EXOCYTOSIS; GENES, REPORTER; GLUCOSE; HYDROGEN-ION CONCENTRATION; INSULIN; ISLETS OF LANGERHANS; MICROSCOPY, CONFOCAL; NEUROPEPTIDE Y; PROINSULIN; PROTEIN PRECURSORS; RATS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SYNAPTOTAGMINS;

EID: 33744474156     PISSN: 00121797     EISSN: 00121797     Source Type: Journal    
DOI: 10.2337/diabetes.55.04.06.db05-1577     Document Type: Article

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