Troglitazone prevents mitochondrial alterations, β cell destruction, and diabetes in obese prediabetic rats

Proceedings of the National Academy of Sciences of the United States of America

Volumn 96, Issue 20, 1999, Pages 11513-11518

  Higa, Moritake ^a,b   Zhou, Yan Ting ^a,b   Ravazzola, Mariella ^c   Baetens, Danielle ^c   Orci, Lelio ^c   Unger, Roger H ^a,b  

^a UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^b VA NORTH TEXAS HEALTH CARE SYSTEM   (United States)

^c UNIVERSITY OF GENEVA MEDICAL SCHOOL   (Switzerland)

Author keywords

Lipoapoptosis; Lipotoxicity; Zucker Diabetic Fatty rats

Indexed keywords

TROGLITAZONE;

ANIMAL CELL; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL PROTECTION; CONTROLLED STUDY; CYTOARCHITECTURE; DIABETES MELLITUS; DRUG MECHANISM; HISTOPATHOLOGY; INSULIN SENSITIVITY; LIPID METABOLISM; MITOCHONDRIAL RESPIRATION; NONHUMAN; OBESITY; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL;

ANIMALS; BLOOD GLUCOSE; BODY WEIGHT; CHROMANS; DIABETES MELLITUS; EATING; HYPOGLYCEMIC AGENTS; ISLETS OF LANGERHANS; LIPIDS; MITOCHONDRIA; OBESITY; RATS; THIAZOLES; THIAZOLIDINEDIONES; TRIGLYCERIDES;

ANIMALIA;

EID: 0033613181     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.96.20.11513     Document Type: Article

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