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Volumn 1762, Issue 11-12, 2006, Pages 973-985

Amyotrophic lateral sclerosis as a complex genetic disease

Author keywords

Amyotrophic lateral sclerosis; Association study; Complex disease; Complex genetic; Gene; Genetic; Sporadic

Indexed keywords

ANGIOGENIN; APOLIPOPROTEIN E; CILIARY NEUROTROPHIC FACTOR; COPPER ZINC SUPEROXIDE DISMUTASE; DYNACTIN; DYNEIN ADENOSINE TRIPHOSPHATASE; PERIPHERIN; SURVIVAL MOTOR NEURON PROTEIN; VASCULOTROPIN;

EID: 33751120678     PISSN: 09254439     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbadis.2006.08.001     Document Type: Review
Times cited : (71)

References (156)
  • 1
    • 77049209200 scopus 로고
    • Epidemiologic investigations of amyotrophic lateral sclerosis. 2. Familial aggregations indicative of dominant inheritance
    • Kurland L.T., and Mulder D.W. Epidemiologic investigations of amyotrophic lateral sclerosis. 2. Familial aggregations indicative of dominant inheritance. I Neurology 5 (1955) 182-196
    • (1955) I Neurology , vol.5 , pp. 182-196
    • Kurland, L.T.1    Mulder, D.W.2
  • 5
    • 0030780350 scopus 로고    scopus 로고
    • Copper/zinc superoxide dismutase 1 and sporadic amyotrophic lateral sclerosis: analysis of 155 cases and identification of a novel insertion mutation
    • Jackson M., Al-Chalabi A., Enayat Z.E., Chioza B., Leigh P.N., and Morrison K.E. Copper/zinc superoxide dismutase 1 and sporadic amyotrophic lateral sclerosis: analysis of 155 cases and identification of a novel insertion mutation. Ann. Neurol. 42 (1997) 803-807
    • (1997) Ann. Neurol. , vol.42 , pp. 803-807
    • Jackson, M.1    Al-Chalabi, A.2    Enayat, Z.E.3    Chioza, B.4    Leigh, P.N.5    Morrison, K.E.6
  • 6
    • 0027944708 scopus 로고
    • Identification of a novel exon 4 SOD1 mutation in a sporadic amyotrophic lateral sclerosis patient
    • Jones C.T., Shaw P.J., Chari G., and Brock D.J. Identification of a novel exon 4 SOD1 mutation in a sporadic amyotrophic lateral sclerosis patient. Mol. Cell. Probes 8 (1994) 329-330
    • (1994) Mol. Cell. Probes , vol.8 , pp. 329-330
    • Jones, C.T.1    Shaw, P.J.2    Chari, G.3    Brock, D.J.4
  • 7
    • 0028273306 scopus 로고
    • Identification of a novel SOD1 mutation in an apparently sporadic amyotrophic lateral sclerosis patient and the detection of Ile113Thr in three others
    • Jones C.T., Swingler R.J., and Brock D.J. Identification of a novel SOD1 mutation in an apparently sporadic amyotrophic lateral sclerosis patient and the detection of Ile113Thr in three others. Hum. Mol. Genet. 3 (1994) 649-650
    • (1994) Hum. Mol. Genet. , vol.3 , pp. 649-650
    • Jones, C.T.1    Swingler, R.J.2    Brock, D.J.3
  • 8
    • 33751111111 scopus 로고    scopus 로고
    • C.A.S. Johnston, B.R., M.R. Turner, R. Gray, H.-M. Blunt, D. Butt, M.A. Ampong, C.E. Shaw, P.N. Leigh, A. Al-Chalabi, Amyotrophic Lateral Sclerosis in an Urban Setting: a population based study of inner city London. J. Neurol. (in press).
  • 11
    • 0027987314 scopus 로고
    • Genetic heterogeneity of apolipoprotein E and its influence on plasma lipid and lipoprotein levels
    • de Knijff P., van den Maagdenberg A.M., Frants R.R., and Havekes L.M. Genetic heterogeneity of apolipoprotein E and its influence on plasma lipid and lipoprotein levels. Hum. Mutat. 4 (1994) 178-194
    • (1994) Hum. Mutat. , vol.4 , pp. 178-194
    • de Knijff, P.1    van den Maagdenberg, A.M.2    Frants, R.R.3    Havekes, L.M.4
  • 17
    • 27644546646 scopus 로고    scopus 로고
    • The association between APOE epsilon4, age and outcome after head injury: a prospective cohort study
    • Teasdale G.M., Murray G.D., and Nicoll J.A. The association between APOE epsilon4, age and outcome after head injury: a prospective cohort study. Brain 128 (2005) 2556-2561
    • (2005) Brain , vol.128 , pp. 2556-2561
    • Teasdale, G.M.1    Murray, G.D.2    Nicoll, J.A.3
  • 18
    • 0030770308 scopus 로고    scopus 로고
    • Association of apolipoprotein E polymorphism with outcome after head injury
    • Teasdale G.M., Nicoll J.A., Murray G., and Fiddes M. Association of apolipoprotein E polymorphism with outcome after head injury. Lancet 350 (1997) 1069-1071
    • (1997) Lancet , vol.350 , pp. 1069-1071
    • Teasdale, G.M.1    Nicoll, J.A.2    Murray, G.3    Fiddes, M.4
  • 19
    • 0028991091 scopus 로고
    • Apolipoprotein E epsilon 4 allele is not associated with earlier age at onset in amyotrophic lateral sclerosis
    • Mui S., Rebeck G.W., McKenna-Yasek D., Hyman B.T., and Brown Jr. R.H. Apolipoprotein E epsilon 4 allele is not associated with earlier age at onset in amyotrophic lateral sclerosis. Ann. Neurol. 38 (1995) 460-463
    • (1995) Ann. Neurol. , vol.38 , pp. 460-463
    • Mui, S.1    Rebeck, G.W.2    McKenna-Yasek, D.3    Hyman, B.T.4    Brown Jr., R.H.5
  • 21
    • 0031055605 scopus 로고    scopus 로고
    • Lack of association of apolipoprotein E epsilon 4 allele with bulbar-onset motor neuron disease
    • Bachus R., Bader S., Gessner R., and Ludolph A.C. Lack of association of apolipoprotein E epsilon 4 allele with bulbar-onset motor neuron disease. Ann. Neurol. 41 (1997) 417
    • (1997) Ann. Neurol. , vol.41 , pp. 417
    • Bachus, R.1    Bader, S.2    Gessner, R.3    Ludolph, A.C.4
  • 22
    • 0029666061 scopus 로고    scopus 로고
    • Apolipoprotein E epsilon 4 in bulbar-onset motor neuron disease
    • Smith R.G., Haverkamp L.J., Case S., Appel V., and Appel S.H. Apolipoprotein E epsilon 4 in bulbar-onset motor neuron disease. Lancet 348 (1996) 334-335
    • (1996) Lancet , vol.348 , pp. 334-335
    • Smith, R.G.1    Haverkamp, L.J.2    Case, S.3    Appel, V.4    Appel, S.H.5
  • 24
    • 0029787386 scopus 로고    scopus 로고
    • Apolipoprotein E genotyping in sporadic amyotrophic lateral sclerosis: evidence for a major influence on the clinical presentation and prognosis
    • (Suppl.)
    • Moulard B., Sefiani A., Laamri A., Malafosse A., and Camu W. Apolipoprotein E genotyping in sporadic amyotrophic lateral sclerosis: evidence for a major influence on the clinical presentation and prognosis. J. Neurol. Sci. 139 (1996) 34-37 (Suppl.)
    • (1996) J. Neurol. Sci. , vol.139 , pp. 34-37
    • Moulard, B.1    Sefiani, A.2    Laamri, A.3    Malafosse, A.4    Camu, W.5
  • 25
    • 0035885774 scopus 로고    scopus 로고
    • Association of APOE epsilon4 allele with survival in amyotrophic lateral sclerosis
    • Drory V.E., Birnbaum M., Korczyn A.D., and Chapman J. Association of APOE epsilon4 allele with survival in amyotrophic lateral sclerosis. J. Neurol. Sci. 190 (2001) 17-20
    • (2001) J. Neurol. Sci. , vol.190 , pp. 17-20
    • Drory, V.E.1    Birnbaum, M.2    Korczyn, A.D.3    Chapman, J.4
  • 26
    • 0023235253 scopus 로고
    • Haplotype relative risks: an easy reliable way to construct a proper control sample for risk calculations
    • Falk C.a.R., and P. Haplotype relative risks: an easy reliable way to construct a proper control sample for risk calculations. Ann. Hum. Genet. 51 (1987) 227-233
    • (1987) Ann. Hum. Genet. , vol.51 , pp. 227-233
    • Falk C.A.R., P.1
  • 27
    • 0027377799 scopus 로고
    • Transmission test for linkage disequilibrium: the insulin gene region and insulin-dependent diabetes mellitus (IDDM)
    • Spielman R.a.M., R.E., and Ewens W.J. Transmission test for linkage disequilibrium: the insulin gene region and insulin-dependent diabetes mellitus (IDDM). Am. J. Hum. Genet. 52 (1993) 506-516
    • (1993) Am. J. Hum. Genet. , vol.52 , pp. 506-516
    • Spielman, R.a.M.1    Ewens, W.J.2
  • 31
    • 0032796004 scopus 로고    scopus 로고
    • Mutational analysis of the Cu/Zn superoxide dismutase gene in 23 familial and 69 sporadic cases of amyotrophic lateral sclerosis in Belgium
    • Aguirre T., Matthijs G., Robberecht W., Tilkin P., and Cassiman J.J. Mutational analysis of the Cu/Zn superoxide dismutase gene in 23 familial and 69 sporadic cases of amyotrophic lateral sclerosis in Belgium. Eur. J. Hum. Genet. 7 (1999) 599-602
    • (1999) Eur. J. Hum. Genet. , vol.7 , pp. 599-602
    • Aguirre, T.1    Matthijs, G.2    Robberecht, W.3    Tilkin, P.4    Cassiman, J.J.5
  • 32
    • 0029854883 scopus 로고    scopus 로고
    • D90A heterozygosity in the SOD1 gene is associated with familial and apparently sporadic amyotrophic lateral sclerosis
    • Robberecht W., Aguirre T., Van den Bosch L., Tilkin P., Cassiman J.J., and Matthijs G. D90A heterozygosity in the SOD1 gene is associated with familial and apparently sporadic amyotrophic lateral sclerosis. Neurology 47 (1996) 1336-1339
    • (1996) Neurology , vol.47 , pp. 1336-1339
    • Robberecht, W.1    Aguirre, T.2    Van den Bosch, L.3    Tilkin, P.4    Cassiman, J.J.5    Matthijs, G.6
  • 34
    • 0029815265 scopus 로고    scopus 로고
    • An update on superoxide dismutase 1 in familial amyotrophic lateral sclerosis
    • (Suppl.)
    • Cudkowicz M.E., and Brown Jr. R.H. An update on superoxide dismutase 1 in familial amyotrophic lateral sclerosis. J. Neurol. Sci. 139 (1996) 10-15 (Suppl.)
    • (1996) J. Neurol. Sci. , vol.139 , pp. 10-15
    • Cudkowicz, M.E.1    Brown Jr., R.H.2
  • 37
    • 0036885011 scopus 로고    scopus 로고
    • D90A-SOD1 mediated amyotrophic lateral sclerosis: a single founder for all cases with evidence for a Cis-acting disease modifier in the recessive haplotype
    • Parton M.J., Broom W., Andersen P.M., Al-Chalabi A., Nigel Leigh P., Powell J.F., and Shaw C.E. D90A-SOD1 mediated amyotrophic lateral sclerosis: a single founder for all cases with evidence for a Cis-acting disease modifier in the recessive haplotype. Hum. Mutat. 20 (2002) 473
    • (2002) Hum. Mutat. , vol.20 , pp. 473
    • Parton, M.J.1    Broom, W.2    Andersen, P.M.3    Al-Chalabi, A.4    Nigel Leigh, P.5    Powell, J.F.6    Shaw, C.E.7
  • 38
    • 28744434903 scopus 로고    scopus 로고
    • Variants in candidate ALS modifier genes linked to Cu/Zn superoxide dismutase do not explain divergent survival phenotypes
    • Broom W.J., Russ C., Sapp P.C., McKenna-Yasek D., Hosler B.A., Andersen P.M., and Brown Jr. R.H. Variants in candidate ALS modifier genes linked to Cu/Zn superoxide dismutase do not explain divergent survival phenotypes. Neurosci. Lett. 392 (2006) 52-57
    • (2006) Neurosci. Lett. , vol.392 , pp. 52-57
    • Broom, W.J.1    Russ, C.2    Sapp, P.C.3    McKenna-Yasek, D.4    Hosler, B.A.5    Andersen, P.M.6    Brown Jr., R.H.7
  • 40
  • 41
    • 0018764763 scopus 로고
    • Cholinergic neuronotrophic factors: intraocular distribution of trophic activity for ciliary neurons
    • Adler R., Landa K.B., Manthorpe M., and Varon S. Cholinergic neuronotrophic factors: intraocular distribution of trophic activity for ciliary neurons. Science 204 (1979) 1434-1436
    • (1979) Science , vol.204 , pp. 1434-1436
    • Adler, R.1    Landa, K.B.2    Manthorpe, M.3    Varon, S.4
  • 42
    • 0029117805 scopus 로고
    • Ciliary neurotrophic factor promotes the survival of spinal sensory neurons following axotomy but not during the period of programmed cell death
    • Lo A.C., Li L., Oppenheim R.W., Prevette D., and Houenou L.J. Ciliary neurotrophic factor promotes the survival of spinal sensory neurons following axotomy but not during the period of programmed cell death. Exp. Neurol. 134 (1995) 49-55
    • (1995) Exp. Neurol. , vol.134 , pp. 49-55
    • Lo, A.C.1    Li, L.2    Oppenheim, R.W.3    Prevette, D.4    Houenou, L.J.5
  • 44
    • 0025325548 scopus 로고
    • Ciliary neurotrophic factor prevents the degeneration of motor neurons after axotomy
    • Sendtner M., Kreutzberg G.W., and Thoenen H. Ciliary neurotrophic factor prevents the degeneration of motor neurons after axotomy. Nature 345 (1990) 440-441
    • (1990) Nature , vol.345 , pp. 440-441
    • Sendtner, M.1    Kreutzberg, G.W.2    Thoenen, H.3
  • 45
    • 0029940555 scopus 로고    scopus 로고
    • The neurotrophins and CNTF: two families of collaborative neurotrophic factors
    • Ip N.Y., and Yancopoulos G.D. The neurotrophins and CNTF: two families of collaborative neurotrophic factors. Annu. Rev. Neurosci. 19 (1996) 491-515
    • (1996) Annu. Rev. Neurosci. , vol.19 , pp. 491-515
    • Ip, N.Y.1    Yancopoulos, G.D.2
  • 46
    • 0026749255 scopus 로고
    • Ciliary neurotrophic factor prevents degeneration of motor neurons in mouse mutant progressive motor neuronopathy
    • Sendtner M., Schmalbruch H., Stockli K.A., Carroll P., Kreutzberg G.W., and Thoenen H. Ciliary neurotrophic factor prevents degeneration of motor neurons in mouse mutant progressive motor neuronopathy. Nature 358 (1992) 502-504
    • (1992) Nature , vol.358 , pp. 502-504
    • Sendtner, M.1    Schmalbruch, H.2    Stockli, K.A.3    Carroll, P.4    Kreutzberg, G.W.5    Thoenen, H.6
  • 47
    • 0027484249 scopus 로고
    • Disruption of the CNTF gene results in motor neuron degeneration
    • Masu Y., Wolf E., Holtmann B., Sendtner M., Brem G., and Thoenen H. Disruption of the CNTF gene results in motor neuron degeneration. Nature 365 (1993) 27-32
    • (1993) Nature , vol.365 , pp. 27-32
    • Masu, Y.1    Wolf, E.2    Holtmann, B.3    Sendtner, M.4    Brem, G.5    Thoenen, H.6
  • 49
    • 0029142863 scopus 로고
    • Investigation of a null mutation of the CNTF gene in familial amyotrophic lateral sclerosis
    • Orrell R.W., King A.W., Lane R.J., and de Belleroche J.S. Investigation of a null mutation of the CNTF gene in familial amyotrophic lateral sclerosis. J. Neurol. Sci. 132 (1995) 126-128
    • (1995) J. Neurol. Sci. , vol.132 , pp. 126-128
    • Orrell, R.W.1    King, A.W.2    Lane, R.J.3    de Belleroche, J.S.4
  • 50
    • 0029553701 scopus 로고
    • Deficiency of human ciliary neurotropic factor (CNTF) is not causally related to amyotrophic lateral sclerosis (ALS)
    • Takahashi R. Deficiency of human ciliary neurotropic factor (CNTF) is not causally related to amyotrophic lateral sclerosis (ALS). Rinsho Shinkeigaku 35 (1995) 1543-1545
    • (1995) Rinsho Shinkeigaku , vol.35 , pp. 1543-1545
    • Takahashi, R.1
  • 51
    • 0028021552 scopus 로고
    • A null mutation in the human CNTF gene is not causally related to neurological diseases
    • Takahashi R., Yokoji H., Misawa H., Hayashi M., Hu J., and Deguchi T. A null mutation in the human CNTF gene is not causally related to neurological diseases. Nat. Genet. 7 (1994) 79-84
    • (1994) Nat. Genet. , vol.7 , pp. 79-84
    • Takahashi, R.1    Yokoji, H.2    Misawa, H.3    Hayashi, M.4    Hu, J.5    Deguchi, T.6
  • 52
    • 0031890907 scopus 로고    scopus 로고
    • Potential implications of a ciliary neurotrophic factor gene mutation in a German population of patients with motor neuron disease
    • Giess R., Goetz R., Schrank B., Ochs G., Sendtner M., and Toyka K. Potential implications of a ciliary neurotrophic factor gene mutation in a German population of patients with motor neuron disease. Muscle Nerve 21 (1998) 236-238
    • (1998) Muscle Nerve , vol.21 , pp. 236-238
    • Giess, R.1    Goetz, R.2    Schrank, B.3    Ochs, G.4    Sendtner, M.5    Toyka, K.6
  • 54
    • 0029021660 scopus 로고
    • Role of the Flt-1 receptor tyrosine kinase in regulating the assembly of vascular endothelium
    • Fong G.H., Rossant J., Gertsenstein M., and Breitman M.L. Role of the Flt-1 receptor tyrosine kinase in regulating the assembly of vascular endothelium. Nature 376 (1995) 66-70
    • (1995) Nature , vol.376 , pp. 66-70
    • Fong, G.H.1    Rossant, J.2    Gertsenstein, M.3    Breitman, M.L.4
  • 55
    • 0032549799 scopus 로고    scopus 로고
    • Neuropilin-1 is expressed by endothelial and tumor cells as an isoform-specific receptor for vascular endothelial growth factor
    • Soker S., Takashima S., Miao H.Q., Neufeld G., and Klagsbrun M. Neuropilin-1 is expressed by endothelial and tumor cells as an isoform-specific receptor for vascular endothelial growth factor. Cell 92 (1998) 735-745
    • (1998) Cell , vol.92 , pp. 735-745
    • Soker, S.1    Takashima, S.2    Miao, H.Q.3    Neufeld, G.4    Klagsbrun, M.5
  • 56
    • 0031683937 scopus 로고    scopus 로고
    • Expression of vascular endothelial growth factor (VEGF) and its receptors (Flt-1 and Flk-1) following permanent and transient occlusion of the middle cerebral artery in the rat
    • Lennmyr F., Ata K.A., Funa K., Olsson Y., and Terent A. Expression of vascular endothelial growth factor (VEGF) and its receptors (Flt-1 and Flk-1) following permanent and transient occlusion of the middle cerebral artery in the rat. J. Neuropathol. Exp. Neurol. 57 (1998) 874-882
    • (1998) J. Neuropathol. Exp. Neurol. , vol.57 , pp. 874-882
    • Lennmyr, F.1    Ata, K.A.2    Funa, K.3    Olsson, Y.4    Terent, A.5
  • 57
    • 0029839804 scopus 로고    scopus 로고
    • Flk-1, a receptor for vascular endothelial growth factor (VEGF), is expressed by retinal progenitor cells
    • Yang K., and Cepko C.L. Flk-1, a receptor for vascular endothelial growth factor (VEGF), is expressed by retinal progenitor cells. J. Neurosci. 16 (1996) 6089-6099
    • (1996) J. Neurosci. , vol.16 , pp. 6089-6099
    • Yang, K.1    Cepko, C.L.2
  • 58
    • 0033565417 scopus 로고    scopus 로고
    • Vascular endothelial growth factor has neurotrophic activity and stimulates axonal outgrowth, enhancing cell survival and Schwann cell proliferation in the peripheral nervous system
    • Sondell M., Lundborg G., and Kanje M. Vascular endothelial growth factor has neurotrophic activity and stimulates axonal outgrowth, enhancing cell survival and Schwann cell proliferation in the peripheral nervous system. J. Neurosci. 19 (1999) 5731-5740
    • (1999) J. Neurosci. , vol.19 , pp. 5731-5740
    • Sondell, M.1    Lundborg, G.2    Kanje, M.3
  • 62
  • 63
    • 20044384733 scopus 로고    scopus 로고
    • Screening of the regulatory and coding regions of vascular endothelial growth factor in amyotrophic lateral sclerosis
    • Brockington A., Kirby J., Eggitt D., Schofield E., Morris C., Lewis C.E., Ince P.G., and Shaw P.J. Screening of the regulatory and coding regions of vascular endothelial growth factor in amyotrophic lateral sclerosis. Neurogenetics 6 (2005) 101-104
    • (2005) Neurogenetics , vol.6 , pp. 101-104
    • Brockington, A.1    Kirby, J.2    Eggitt, D.3    Schofield, E.4    Morris, C.5    Lewis, C.E.6    Ince, P.G.7    Shaw, P.J.8
  • 66
    • 0021368680 scopus 로고
    • Neurofibrillary axonal swellings and amyotrophic lateral sclerosis
    • Delisle M.B., and Carpenter S. Neurofibrillary axonal swellings and amyotrophic lateral sclerosis. J. Neurol. Sci. 63 (1984) 241-250
    • (1984) J. Neurol. Sci. , vol.63 , pp. 241-250
    • Delisle, M.B.1    Carpenter, S.2
  • 67
    • 0026692757 scopus 로고
    • Basophilic inclusions in sporadic juvenile amyotrophic lateral sclerosis: an immunocytochemical and ultrastructural study
    • Matsumoto S., Kusaka H., Murakami N., Hashizume Y., Okazaki H., and Hirano A. Basophilic inclusions in sporadic juvenile amyotrophic lateral sclerosis: an immunocytochemical and ultrastructural study. Acta Neuropathol. (Berl.) 83 (1992) 579-583
    • (1992) Acta Neuropathol. (Berl.) , vol.83 , pp. 579-583
    • Matsumoto, S.1    Kusaka, H.2    Murakami, N.3    Hashizume, Y.4    Okazaki, H.5    Hirano, A.6
  • 68
    • 0024428392 scopus 로고
    • Focal accumulation of phosphorylated neurofilaments within anterior horn cell in familial amyotrophic lateral sclerosis
    • Mizusawa H., Matsumoto S., Yen S.H., Hirano A., Rojas-Corona R.R., and Donnenfeld H. Focal accumulation of phosphorylated neurofilaments within anterior horn cell in familial amyotrophic lateral sclerosis. Acta Neuropathol. (Berl.) 79 (1989) 37-43
    • (1989) Acta Neuropathol. (Berl.) , vol.79 , pp. 37-43
    • Mizusawa, H.1    Matsumoto, S.2    Yen, S.H.3    Hirano, A.4    Rojas-Corona, R.R.5    Donnenfeld, H.6
  • 69
    • 0026452101 scopus 로고
    • Neurofilament and glial alterations in the cerebral cortex in amyotrophic lateral sclerosis
    • Troost D., Sillevis Smitt P.A., de Jong J.M., and Swaab D.F. Neurofilament and glial alterations in the cerebral cortex in amyotrophic lateral sclerosis. Acta Neuropathol. (Berl.) 84 (1992) 664-673
    • (1992) Acta Neuropathol. (Berl.) , vol.84 , pp. 664-673
    • Troost, D.1    Sillevis Smitt, P.A.2    de Jong, J.M.3    Swaab, D.F.4
  • 70
    • 0027465098 scopus 로고
    • Progressive neuronopathy in transgenic mice expressing the human neurofilament heavy gene: a mouse model of amyotrophic lateral sclerosis
    • Cote F., Collard J.F., and Julien J.P. Progressive neuronopathy in transgenic mice expressing the human neurofilament heavy gene: a mouse model of amyotrophic lateral sclerosis. Cell 73 (1993) 35-46
    • (1993) Cell , vol.73 , pp. 35-46
    • Cote, F.1    Collard, J.F.2    Julien, J.P.3
  • 71
    • 0027410516 scopus 로고
    • Increased expression of neurofilament subunit NF-L produces morphological alterations that resemble the pathology of human motor neuron disease
    • Xu Z., Cork L.C., Griffin J.W., and Cleveland D.W. Increased expression of neurofilament subunit NF-L produces morphological alterations that resemble the pathology of human motor neuron disease. Cell 73 (1993) 23-33
    • (1993) Cell , vol.73 , pp. 23-33
    • Xu, Z.1    Cork, L.C.2    Griffin, J.W.3    Cleveland, D.W.4
  • 72
    • 0032482976 scopus 로고    scopus 로고
    • Absence of neurofilaments reduces the selective vulnerability of motor neurons and slows disease caused by a familial amyotrophic lateral sclerosis-linked superoxide dismutase 1 mutant
    • Williamson T.L., Bruijn L.I., Zhu Q., Anderson K.L., Anderson S.D., Julien J.P., and Cleveland D.W. Absence of neurofilaments reduces the selective vulnerability of motor neurons and slows disease caused by a familial amyotrophic lateral sclerosis-linked superoxide dismutase 1 mutant. Proc. Natl. Acad. Sci. U. S. A. 95 (1998) 9631-9636
    • (1998) Proc. Natl. Acad. Sci. U. S. A. , vol.95 , pp. 9631-9636
    • Williamson, T.L.1    Bruijn, L.I.2    Zhu, Q.3    Anderson, K.L.4    Anderson, S.D.5    Julien, J.P.6    Cleveland, D.W.7
  • 73
    • 0032483016 scopus 로고    scopus 로고
    • Protective effect of neurofilament heavy gene overexpression in motor neuron disease induced by mutant superoxide dismutase
    • Couillard-Despres S., Zhu Q., Wong P.C., Price D.L., Cleveland D.W., and Julien J.P. Protective effect of neurofilament heavy gene overexpression in motor neuron disease induced by mutant superoxide dismutase. Proc. Natl. Acad. Sci. U. S. A. 95 (1998) 9626-9630
    • (1998) Proc. Natl. Acad. Sci. U. S. A. , vol.95 , pp. 9626-9630
    • Couillard-Despres, S.1    Zhu, Q.2    Wong, P.C.3    Price, D.L.4    Cleveland, D.W.5    Julien, J.P.6
  • 74
    • 0033953140 scopus 로고    scopus 로고
    • Overexpression of neurofilament subunit NF-L and NF-H extends survival of a mouse model for amyotrophic lateral sclerosis
    • Kong J., and Xu Z. Overexpression of neurofilament subunit NF-L and NF-H extends survival of a mouse model for amyotrophic lateral sclerosis. Neurosci. Lett. 281 (2000) 72-74
    • (2000) Neurosci. Lett. , vol.281 , pp. 72-74
    • Kong, J.1    Xu, Z.2
  • 75
    • 0033830020 scopus 로고    scopus 로고
    • Extra axonal neurofilaments do not exacerbate disease caused by mutant Cu,Zn superoxide dismutase
    • Couillard-Despres S., Meier J., and Julien J.P. Extra axonal neurofilaments do not exacerbate disease caused by mutant Cu,Zn superoxide dismutase. Neurobiol. Dis. 7 (2000) 462-470
    • (2000) Neurobiol. Dis. , vol.7 , pp. 462-470
    • Couillard-Despres, S.1    Meier, J.2    Julien, J.P.3
  • 76
    • 0027424206 scopus 로고
    • Polymorphism in the multi-phosphorylation domain of the human neurofilament heavy-subunit-encoding gene
    • Figlewicz D.A., Rouleau G.A., Krizus A., and Julien J.P. Polymorphism in the multi-phosphorylation domain of the human neurofilament heavy-subunit-encoding gene. Gene 132 (1993) 297-300
    • (1993) Gene , vol.132 , pp. 297-300
    • Figlewicz, D.A.1    Rouleau, G.A.2    Krizus, A.3    Julien, J.P.4
  • 77
    • 0028001606 scopus 로고
    • Variants of the heavy neurofilament subunit are associated with the development of amyotrophic lateral sclerosis
    • Figlewicz D.A., Krizus A., Martinoli M.G., Meininger V., Dib M., Rouleau G.A., and Julien J.P. Variants of the heavy neurofilament subunit are associated with the development of amyotrophic lateral sclerosis. Hum. Mol. Genet. 3 (1994) 1757-1761
    • (1994) Hum. Mol. Genet. , vol.3 , pp. 1757-1761
    • Figlewicz, D.A.1    Krizus, A.2    Martinoli, M.G.3    Meininger, V.4    Dib, M.5    Rouleau, G.A.6    Julien, J.P.7
  • 78
    • 0030000608 scopus 로고    scopus 로고
    • Analysis of the KSP repeat of the neurofilament heavy subunit in familiar amyotrophic lateral sclerosis
    • Rooke K., Figlewicz D.A., Han F.Y., and Rouleau G.A. Analysis of the KSP repeat of the neurofilament heavy subunit in familiar amyotrophic lateral sclerosis. Neurology 46 (1996) 789-790
    • (1996) Neurology , vol.46 , pp. 789-790
    • Rooke, K.1    Figlewicz, D.A.2    Han, F.Y.3    Rouleau, G.A.4
  • 79
    • 0029970685 scopus 로고    scopus 로고
    • Sequence variants in human neurofilament proteins: absence of linkage to familial amyotrophic lateral sclerosis
    • Vechio J.D., Bruijn L.I., Xu Z., Brown Jr. R.H., and Cleveland D.W. Sequence variants in human neurofilament proteins: absence of linkage to familial amyotrophic lateral sclerosis. Ann. Neurol. 40 (1996) 603-610
    • (1996) Ann. Neurol. , vol.40 , pp. 603-610
    • Vechio, J.D.1    Bruijn, L.I.2    Xu, Z.3    Brown Jr., R.H.4    Cleveland, D.W.5
  • 81
    • 0032427646 scopus 로고    scopus 로고
    • Novel insertion in the KSP region of the neurofilament heavy gene in amyotrophic lateral sclerosis (ALS)
    • Tomkins J., Usher P., Slade J.Y., Ince P.G., Curtis A., Bushby K., and Shaw P.J. Novel insertion in the KSP region of the neurofilament heavy gene in amyotrophic lateral sclerosis (ALS). NeuroReport 9 (1998) 3967-3970
    • (1998) NeuroReport , vol.9 , pp. 3967-3970
    • Tomkins, J.1    Usher, P.2    Slade, J.Y.3    Ince, P.G.4    Curtis, A.5    Bushby, K.6    Shaw, P.J.7
  • 85
    • 0020875647 scopus 로고
    • Peripherin, a new member of the intermediate filament protein family
    • Portier M.M., de Nechaud B., and Gros F. Peripherin, a new member of the intermediate filament protein family. Dev. Neurosci. 6 (1983) 335-344
    • (1983) Dev. Neurosci. , vol.6 , pp. 335-344
    • Portier, M.M.1    de Nechaud, B.2    Gros, F.3
  • 88
    • 0035839187 scopus 로고    scopus 로고
    • Impaired retrograde axonal transport of adenovirus-mediated E. coli LacZ gene in the mice carrying mutant SOD1 gene
    • Murakami T., Nagano I., Hayashi T., Manabe Y., Shoji M., Setoguchi Y., and Abe K. Impaired retrograde axonal transport of adenovirus-mediated E. coli LacZ gene in the mice carrying mutant SOD1 gene. Neurosci. Lett. 308 (2001) 149-152
    • (2001) Neurosci. Lett. , vol.308 , pp. 149-152
    • Murakami, T.1    Nagano, I.2    Hayashi, T.3    Manabe, Y.4    Shoji, M.5    Setoguchi, Y.6    Abe, K.7
  • 89
    • 0032489870 scopus 로고    scopus 로고
    • Golgi vesiculation and lysosome dispersion in cells lacking cytoplasmic dynein
    • Harada A., Takei Y., Kanai Y., Tanaka Y., Nonaka S., and Hirokawa N. Golgi vesiculation and lysosome dispersion in cells lacking cytoplasmic dynein. J. Cell Biol. 141 (1998) 51-59
    • (1998) J. Cell Biol. , vol.141 , pp. 51-59
    • Harada, A.1    Takei, Y.2    Kanai, Y.3    Tanaka, Y.4    Nonaka, S.5    Hirokawa, N.6
  • 93
    • 0037198709 scopus 로고    scopus 로고
    • Dynactin is necessary for synapse stabilization
    • Eaton B.A., Fetter R.D., and Davis G.W. Dynactin is necessary for synapse stabilization. Neuron 34 (2002) 729-741
    • (2002) Neuron , vol.34 , pp. 729-741
    • Eaton, B.A.1    Fetter, R.D.2    Davis, G.W.3
  • 99
    • 0029943383 scopus 로고    scopus 로고
    • Analysis of chromosome 5q13 genes in amyotrophic lateral sclerosis: homozygous NAIP deletion in a sporadic case
    • Jackson M., Morrison K.E., Al-Chalabi A., Bakker M., and Leigh P.N. Analysis of chromosome 5q13 genes in amyotrophic lateral sclerosis: homozygous NAIP deletion in a sporadic case. Ann. Neurol. 39 (1996) 796-800
    • (1996) Ann. Neurol. , vol.39 , pp. 796-800
    • Jackson, M.1    Morrison, K.E.2    Al-Chalabi, A.3    Bakker, M.4    Leigh, P.N.5
  • 100
    • 0031958077 scopus 로고    scopus 로고
    • Association between centromeric deletions of the SMN gene and sporadic adult-onset lower motor neuron disease
    • Moulard B., Salachas F., Chassande B., Briolotti V., Meininger V., Malafosse A., and Camu W. Association between centromeric deletions of the SMN gene and sporadic adult-onset lower motor neuron disease. Ann. Neurol. 43 (1998) 640-644
    • (1998) Ann. Neurol. , vol.43 , pp. 640-644
    • Moulard, B.1    Salachas, F.2    Chassande, B.3    Briolotti, V.4    Meininger, V.5    Malafosse, A.6    Camu, W.7
  • 101
    • 0030899577 scopus 로고    scopus 로고
    • The relationship of spinal muscular atrophy to motor neuron disease: investigation of SMN and NAIP gene deletions in sporadic and familial ALS
    • Orrell R.W., Habgood J.J., de Belleroche J.S., and Lane R.J. The relationship of spinal muscular atrophy to motor neuron disease: investigation of SMN and NAIP gene deletions in sporadic and familial ALS. J. Neurol. Sci. 145 (1997) 55-61
    • (1997) J. Neurol. Sci. , vol.145 , pp. 55-61
    • Orrell, R.W.1    Habgood, J.J.2    de Belleroche, J.S.3    Lane, R.J.4
  • 106
    • 0034537966 scopus 로고    scopus 로고
    • Genetic mapping of a mouse modifier gene that can prevent ALS onset
    • Kunst C.B., Messer L., Gordon J., Haines J., and Patterson D. Genetic mapping of a mouse modifier gene that can prevent ALS onset. Genomics 70 (2000) 181-189
    • (2000) Genomics , vol.70 , pp. 181-189
    • Kunst, C.B.1    Messer, L.2    Gordon, J.3    Haines, J.4    Patterson, D.5
  • 107
    • 0042975395 scopus 로고    scopus 로고
    • Amyotrophic lateral sclerosis, lead, and genetic susceptibility: polymorphisms in the delta-aminolevulinic acid dehydratase and vitamin D receptor genes
    • Kamel F., Umbach D.M., Lehman T.A., Park L.P., Munsat T.L., Shefner J.M., Sandler D.P., Hu H., and Taylor J.A. Amyotrophic lateral sclerosis, lead, and genetic susceptibility: polymorphisms in the delta-aminolevulinic acid dehydratase and vitamin D receptor genes. Environ. Health Perspect. 111 (2003) 1335-1339
    • (2003) Environ. Health Perspect. , vol.111 , pp. 1335-1339
    • Kamel, F.1    Umbach, D.M.2    Lehman, T.A.3    Park, L.P.4    Munsat, T.L.5    Shefner, J.M.6    Sandler, D.P.7    Hu, H.8    Taylor, J.A.9
  • 115
    • 0033009789 scopus 로고    scopus 로고
    • Molecular genetic analysis of the APEX nuclease gene in amyotrophic lateral sclerosis
    • Hayward C., Colville S., Swingler R.J., and Brock D.J. Molecular genetic analysis of the APEX nuclease gene in amyotrophic lateral sclerosis. Neurology 52 (1999) 1899-1901
    • (1999) Neurology , vol.52 , pp. 1899-1901
    • Hayward, C.1    Colville, S.2    Swingler, R.J.3    Brock, D.J.4
  • 119
    • 0036235860 scopus 로고    scopus 로고
    • Early onset of severe familial amyotrophic lateral sclerosis with a SOD-1 mutation: potential impact of CNTF as a candidate modifier gene
    • Giess R., Holtmann B., Braga M., Grimm T., Muller-Myhsok B., Toyka K.V., and Sendtner M. Early onset of severe familial amyotrophic lateral sclerosis with a SOD-1 mutation: potential impact of CNTF as a candidate modifier gene. Am. J. Hum. Genet. 70 (2002) 1277-1286
    • (2002) Am. J. Hum. Genet. , vol.70 , pp. 1277-1286
    • Giess, R.1    Holtmann, B.2    Braga, M.3    Grimm, T.4    Muller-Myhsok, B.5    Toyka, K.V.6    Sendtner, M.7
  • 121
    • 0029921651 scopus 로고    scopus 로고
    • Debrisoquine hydroxylase gene polymorphism frequencies in patients with amyotrophic lateral sclerosis
    • Siddons M.A., Pickering-Brown S.M., Mann D.M., Owen F., and Cooper P.N. Debrisoquine hydroxylase gene polymorphism frequencies in patients with amyotrophic lateral sclerosis. Neurosci. Lett. 208 (1996) 65-68
    • (1996) Neurosci. Lett. , vol.208 , pp. 65-68
    • Siddons, M.A.1    Pickering-Brown, S.M.2    Mann, D.M.3    Owen, F.4    Cooper, P.N.5
  • 122
    • 0035020941 scopus 로고    scopus 로고
    • Intron 7 retention and exon 9 skipping EAAT2 mRNA variants are not associated with amyotrophic lateral sclerosis
    • Flowers J.M., Powell J.F., Leigh P.N., Andersen P., and Shaw C.E. Intron 7 retention and exon 9 skipping EAAT2 mRNA variants are not associated with amyotrophic lateral sclerosis. Ann. Neurol. 49 (2001) 643-649
    • (2001) Ann. Neurol. , vol.49 , pp. 643-649
    • Flowers, J.M.1    Powell, J.F.2    Leigh, P.N.3    Andersen, P.4    Shaw, C.E.5
  • 123
    • 0034711151 scopus 로고    scopus 로고
    • Glutamate transporter EAAT2 splice variants occur not only in ALS, but also in AD and controls
    • Honig L.S., Chambliss D.D., Bigio E.H., Carroll S.L., and Elliott J.L. Glutamate transporter EAAT2 splice variants occur not only in ALS, but also in AD and controls. Neurology 55 (2000) 1082-1088
    • (2000) Neurology , vol.55 , pp. 1082-1088
    • Honig, L.S.1    Chambliss, D.D.2    Bigio, E.H.3    Carroll, S.L.4    Elliott, J.L.5
  • 124
    • 0033397263 scopus 로고    scopus 로고
    • Polymorphisms in the glutamate transporter gene EAAT2 in European ALS patients
    • Jackson M., Steers G., Leigh P.N., and Morrison K.E. Polymorphisms in the glutamate transporter gene EAAT2 in European ALS patients. J. Neurol. 246 (1999) 1140-1144
    • (1999) J. Neurol. , vol.246 , pp. 1140-1144
    • Jackson, M.1    Steers, G.2    Leigh, P.N.3    Morrison, K.E.4
  • 126
    • 0031755870 scopus 로고    scopus 로고
    • The EAAT2 (GLT-1) gene in motor neuron disease: absence of mutations in amyotrophic lateral sclerosis and a point mutation in patients with hereditary spastic paraplegia
    • Meyer T., Munch C., Volkel H., Booms P., and Ludolph A.C. The EAAT2 (GLT-1) gene in motor neuron disease: absence of mutations in amyotrophic lateral sclerosis and a point mutation in patients with hereditary spastic paraplegia. J. Neurol., Neurosurg. Psychiatry 65 (1998) 594-596
    • (1998) J. Neurol., Neurosurg. Psychiatry , vol.65 , pp. 594-596
    • Meyer, T.1    Munch, C.2    Volkel, H.3    Booms, P.4    Ludolph, A.C.5
  • 127
    • 0031957298 scopus 로고    scopus 로고
    • Mutations in the glutamate transporter EAAT2 gene do not cause abnormal EAAT2 transcripts in amyotrophic lateral sclerosis
    • Aoki M., Lin C.L., Rothstein J.D., Geller B.A., Hosler B.A., Munsat T.L., Horvitz H.R., and Brown Jr. R.H. Mutations in the glutamate transporter EAAT2 gene do not cause abnormal EAAT2 transcripts in amyotrophic lateral sclerosis. Ann. Neurol. 43 (1998) 645-653
    • (1998) Ann. Neurol. , vol.43 , pp. 645-653
    • Aoki, M.1    Lin, C.L.2    Rothstein, J.D.3    Geller, B.A.4    Hosler, B.A.5    Munsat, T.L.6    Horvitz, H.R.7    Brown Jr., R.H.8
  • 128
    • 0032032013 scopus 로고    scopus 로고
    • Aberrant RNA processing in a neurodegenerative disease: the cause for absent EAAT2, a glutamate transporter, in amyotrophic lateral sclerosis
    • Lin C.L., Bristol L.A., Jin L., Dykes-Hoberg M., Crawford T., Clawson L., and Rothstein J.D. Aberrant RNA processing in a neurodegenerative disease: the cause for absent EAAT2, a glutamate transporter, in amyotrophic lateral sclerosis. Neuron 20 (1998) 589-602
    • (1998) Neuron , vol.20 , pp. 589-602
    • Lin, C.L.1    Bristol, L.A.2    Jin, L.3    Dykes-Hoberg, M.4    Crawford, T.5    Clawson, L.6    Rothstein, J.D.7
  • 129
    • 0038798577 scopus 로고    scopus 로고
    • Hexosaminidase A deficiency is an uncommon cause of a syndrome mimicking amyotrophic lateral sclerosis
    • Drory V.E., Birnbaum M., Peleg L., Goldman B., and Korczyn A.D. Hexosaminidase A deficiency is an uncommon cause of a syndrome mimicking amyotrophic lateral sclerosis. Muscle Nerve 28 (2003) 109-112
    • (2003) Muscle Nerve , vol.28 , pp. 109-112
    • Drory, V.E.1    Birnbaum, M.2    Peleg, L.3    Goldman, B.4    Korczyn, A.D.5
  • 130
    • 8544253952 scopus 로고    scopus 로고
    • Increased incidence of the Hfe mutation in amyotrophic lateral sclerosis and related cellular consequences
    • Wang X.S., Lee S., Simmons Z., Boyer P., Scott K., Liu W., and Connor J. Increased incidence of the Hfe mutation in amyotrophic lateral sclerosis and related cellular consequences. J. Neurol. Sci. 227 (2004) 27-33
    • (2004) J. Neurol. Sci. , vol.227 , pp. 27-33
    • Wang, X.S.1    Lee, S.2    Simmons, Z.3    Boyer, P.4    Scott, K.5    Liu, W.6    Connor, J.7
  • 131
    • 2342662119 scopus 로고    scopus 로고
    • HFE mutations are not strongly associated with sporadic ALS
    • Yen A.A., Simpson E.P., Henkel J.S., Beers D.R., and Appel S.H. HFE mutations are not strongly associated with sporadic ALS. Neurology 62 (2004) 1611-1612
    • (2004) Neurology , vol.62 , pp. 1611-1612
    • Yen, A.A.1    Simpson, E.P.2    Henkel, J.S.3    Beers, D.R.4    Appel, S.H.5
  • 132
    • 0034701007 scopus 로고    scopus 로고
    • Potential role of LIF as a modifier gene in the pathogenesis of amyotrophic lateral sclerosis
    • Giess R., Beck M., Goetz R., Nitsch R.M., Toyka K.V., and Sendtner M. Potential role of LIF as a modifier gene in the pathogenesis of amyotrophic lateral sclerosis. Neurology 54 (2000) 1003-1005
    • (2000) Neurology , vol.54 , pp. 1003-1005
    • Giess, R.1    Beck, M.2    Goetz, R.3    Nitsch, R.M.4    Toyka, K.V.5    Sendtner, M.6
  • 133
    • 0028913006 scopus 로고
    • Sporadic ALS and chromosome 22: evidence for a possible neurofilament gene defect
    • Meyer M.A., and Potter N.T. Sporadic ALS and chromosome 22: evidence for a possible neurofilament gene defect. Muscle Nerve 18 (1995) 536-539
    • (1995) Muscle Nerve , vol.18 , pp. 536-539
    • Meyer, M.A.1    Potter, N.T.2
  • 136
    • 0042871270 scopus 로고    scopus 로고
    • Familial amyotrophic lateral sclerosis and parkinsonism-dementia complex-tauopathy without mutations in the tau gene?
    • Kowalska A., Konagaya M., Sakai M., Hashizume Y., and Tabira T. Familial amyotrophic lateral sclerosis and parkinsonism-dementia complex-tauopathy without mutations in the tau gene?. Folia Neuropathol. 41 (2003) 59-64
    • (2003) Folia Neuropathol. , vol.41 , pp. 59-64
    • Kowalska, A.1    Konagaya, M.2    Sakai, M.3    Hashizume, Y.4    Tabira, T.5
  • 138
    • 0034601407 scopus 로고    scopus 로고
    • Mitochondrial DNA deletion mutation levels are elevated in ALS brains
    • Dhaliwal G.K., and Grewal R.P. Mitochondrial DNA deletion mutation levels are elevated in ALS brains. NeuroReport 11 (2000) 2507-2509
    • (2000) NeuroReport , vol.11 , pp. 2507-2509
    • Dhaliwal, G.K.1    Grewal, R.P.2
  • 139
    • 0037291807 scopus 로고    scopus 로고
    • Mitochondrial DNA from platelets of sporadic ALS patients restores normal respiratory functions in rho(0) cells
    • Gajewski C.D., Lin M.T., Cudkowicz M.E., Beal M.F., and Manfredi G. Mitochondrial DNA from platelets of sporadic ALS patients restores
    • (2003) Exp. Neurol. , vol.179 , pp. 229-235
    • Gajewski, C.D.1    Lin, M.T.2    Cudkowicz, M.E.3    Beal, M.F.4    Manfredi, G.5
  • 140
    • 0043065507 scopus 로고    scopus 로고
    • Single-cell analysis of mtDNA in amyotrophic lateral sclerosis: towards the characterization of individual neurons in neurodegenerative disorders
    • Mawrin C., Kirches E., and Dietzmann K. Single-cell analysis of mtDNA in amyotrophic lateral sclerosis: towards the characterization of individual neurons in neurodegenerative disorders. Pathol. Res. Pract. 199 (2003) 415-418
    • (2003) Pathol. Res. Pract. , vol.199 , pp. 415-418
    • Mawrin, C.1    Kirches, E.2    Dietzmann, K.3
  • 142
    • 0344012223 scopus 로고    scopus 로고
    • Deleted 4977-bp mitochondrial DNA mutation is associated with sporadic amyotrophic lateral sclerosis: a hospital-based case-control study
    • Ro L.S., Lai S.L., Chen C.M., and Chen S.T. Deleted 4977-bp mitochondrial DNA mutation is associated with sporadic amyotrophic lateral sclerosis: a hospital-based case-control study. Muscle Nerve 28 (2003) 737-743
    • (2003) Muscle Nerve , vol.28 , pp. 737-743
    • Ro, L.S.1    Lai, S.L.2    Chen, C.M.3    Chen, S.T.4
  • 144
    • 0036321382 scopus 로고    scopus 로고
    • Mitochondrial DNA and respiratory chain function in spinal cords of ALS patients
    • Wiedemann F.R., Manfredi G., Mawrin C., Beal M.F., and Schon E.A. Mitochondrial DNA and respiratory chain function in spinal cords of ALS patients. J. Neurochem. 80 (2002) 616-625
    • (2002) J. Neurochem. , vol.80 , pp. 616-625
    • Wiedemann, F.R.1    Manfredi, G.2    Mawrin, C.3    Beal, M.F.4    Schon, E.A.5
  • 146
    • 0029062287 scopus 로고
    • Mice overexpressing the human neurofilament heavy gene as a model of ALS
    • (discussion 490-2)
    • Julien J.P., Cote F., and Collard J.F. Mice overexpressing the human neurofilament heavy gene as a model of ALS. Neurobiol. Aging 16 (1995) 487-490 (discussion 490-2)
    • (1995) Neurobiol. Aging , vol.16 , pp. 487-490
    • Julien, J.P.1    Cote, F.2    Collard, J.F.3
  • 148
    • 1542380078 scopus 로고    scopus 로고
    • A polymorphism in the poliovirus receptor gene differs in motor neuron disease
    • Saunderson R., Yu B., Trent R.J., and Pamphlett R. A polymorphism in the poliovirus receptor gene differs in motor neuron disease. NeuroReport 15 (2004) 383-386
    • (2004) NeuroReport , vol.15 , pp. 383-386
    • Saunderson, R.1    Yu, B.2    Trent, R.J.3    Pamphlett, R.4
  • 153
    • 0032886839 scopus 로고    scopus 로고
    • Mutations in the gene encoding human persyn are not associated with amyotrophic lateral sclerosis or familial Parkinson's disease
    • Flowers J.M., Leigh P.N., Davies A.M., Ninkina N.N., Buchman V.L., Vaughan J., Wood N.W., and Powell J.F. Mutations in the gene encoding human persyn are not associated with amyotrophic lateral sclerosis or familial Parkinson's disease. Neurosci. Lett. 274 (1999) 21-24
    • (1999) Neurosci. Lett. , vol.274 , pp. 21-24
    • Flowers, J.M.1    Leigh, P.N.2    Davies, A.M.3    Ninkina, N.N.4    Buchman, V.L.5    Vaughan, J.6    Wood, N.W.7    Powell, J.F.8
  • 154
    • 0035828146 scopus 로고    scopus 로고
    • Mutation screening of manganese superoxide dismutase in amyotrophic lateral sclerosis
    • Tomkins J., Banner S.J., McDermott C.J., and Shaw P.J. Mutation screening of manganese superoxide dismutase in amyotrophic lateral sclerosis. NeuroReport 12 (2001) 2319-2322
    • (2001) NeuroReport , vol.12 , pp. 2319-2322
    • Tomkins, J.1    Banner, S.J.2    McDermott, C.J.3    Shaw, P.J.4


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