Association of apolipoprotein E ε4 allele with bulbar-onset motor neuron disease

Lancet

Volumn 347, Issue 8995, 1996, Pages 159-160

  Al Chalabi, Ammar ^a   Enayat, Zinat E ^a   Bakker, Martijn C ^a   Sham, Pak C ^a   Ball, David M ^a   Shaw, Christopher E ^a   Lloyd, Catherine M ^a   Powell, John F ^a   Leigh, P Nigel ^a  

^a KING'S COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID BETA PROTEIN; APOLIPOPROTEIN E;

ALLELE; ALZHEIMER DISEASE; ARTICLE; CONTROLLED STUDY; FEMALE; GENE FREQUENCY; GENOTYPE; HUMAN; MAJOR CLINICAL STUDY; MALE; MOTOR NEURON DISEASE; NEUROFIBRILLARY TANGLE; ONSET AGE; PRIORITY JOURNAL;

EID: 0030025431     PISSN: 01406736     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0140-6736(96)90343-8     Document Type: Article

References (10)

1. Saunders AM, Strittmater WJ, Schmechel D, et al. Association of apolipoprotein e allele epsilon 4 with late onset familial and sporadic Alzheimer's disease. Neurology 1993; 43: 1467-72.
2. Schneider JA, Gearing M, Robbins RS, de l'Aune W, Mirra SS. Apolipoprotein E genotype in diverse neurodegenerative disorders. Ann Neurol 1995; 38: 131-35.
3. Rebeck GW, Reiter JS, Strickland DK, Hyman BT. Apolipoprotein E in sporadic Alzheimer's disease: allelic variation and receptor interactions. Neuron 1993; 11: 575-80.
4. Strittmater WJ, Saunders AM, Schmechel D, et al. Apolipoprotein E: high-avidity binding to b-amyloid and increased frequency of type 4 allele in late-onset familial Alzheimer disease. Proc Natl Acad Sci USA 1993; 90: 1977-81.
5. Namba Y, Tomonaga M, Kawasaki H, Otomo E, Ikeda A. Apolipoprotein E immunoreactivity in cerebral amyloid deposits and neurofibrillary tangles in Alzheimer's disease and kuru plaque amyloid in Creutzfeldt-Jakob disease. Brain Res 1991; 541: 163-66.
6. Mui S, Rebeck W, McKenna-Yasek D, Hyman BT, Brown RH. Apolipoprotein E e4 allele is not associated with earlier age at onset in amyotrophic lateral sclerosis. Ann Neurol 1995; 38: 460-63.
7. Norris F, Shepherd R, Denys E, et al. Onset, natural history and outcome of idiopathic adult motor neuron disease. J Neurol Sci 1993; 118: 48-55.
8. Haverkamp LJ, Appel V, Appel SH. Natural history of amyotrophic lateral sclerosis in a database population. Brain 1995; 118: 707-19.
9. Abrahams S, Goldstein LH, Lloyd CM, Brooks DJ, Leigh PN. Cognitive deficits in non demented amyotrophic lateral sclerosis patients: a neuropsychological investigation. J Neurol Sci 1995; 129 (suppl): 54-55.
10. Whenham PR, Price WH, Blundell G. Apolipoprotein E genotyping by one-stage PCR. Lancet 1991; 337: 1158-59.