Foxp3 controls autoreactive T cell activation through transcriptional regulation of early growth response genes and E3 ubiquitin ligase genes, independently of thymic selection

Clinical Immunology

Volumn 121, Issue 3, 2006, Pages 274-285

  Chang, Xing ^a   Chen, Li ^a   Wen, Jing ^b   Godfrey, Virginia L ^c   Qiao, Guilin ^d   Hussien, Yassir ^d   Zhang, Jian ^d   Gao, Jian Xin ^a,b  

^a THE OHIO STATE UNIVERSITY WEXNER MEDICAL CENTER   (United States)

^b OHIO STATE UNIVERSITY   (United States)

^c UNIVERSITY OF NORTH CAROLINA   (United States)

^d UNIVERSITY OF CHICAGO   (United States)

Author keywords

Autoimmune disease; E3 ubiquitin ligase; Early growth response; Foxp3; Superantigen; T cell tolerance; Thymic selection

Indexed keywords

PHOSPHOLIPASE C GAMMA; PROTEIN; PROTEIN CBLB; PROTEIN GRAIL; PROTEIN ITCH; PROTEIN KINASE; TRANSCRIPTION FACTOR FOXP3; UBIQUITIN PROTEIN LIGASE E3; UNCLASSIFIED DRUG; VIRUS ANTIGEN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL ACTIVATION; MALE; MOUSE; MOUSE STRAIN; MUTANT; NONHUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; T LYMPHOCYTE ACTIVATION; THYMUS; TRANSCRIPTION REGULATION; WILD TYPE;

ANIMALS; ANTIGENS, VIRAL; AUTOIMMUNITY; CELL DIFFERENTIATION; EARLY GROWTH RESPONSE TRANSCRIPTION FACTORS; FORKHEAD TRANSCRIPTION FACTORS; GENE EXPRESSION REGULATION; KINETICS; LYMPHOCYTE ACTIVATION; MICE; MICE, TRANSGENIC; SIGNAL TRANSDUCTION; T-LYMPHOCYTES; THYMUS GLAND; TRANSCRIPTION, GENETIC; UBIQUITIN-PROTEIN LIGASES;

EID: 33751103681     PISSN: 15216616     EISSN: 15217035     Source Type: Journal    
DOI: 10.1016/j.clim.2006.07.004     Document Type: Article

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