메뉴 건너뛰기




Volumn 58, Issue 8, 2006, Pages 948-961

Regulating the immune response to tumours

Author keywords

T regulatory cells; Tumour immunity

Indexed keywords

ANTIGENS; CELLS; DISEASE CONTROL; PATIENT TREATMENT;

EID: 33750733260     PISSN: 0169409X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.addr.2006.05.006     Document Type: Review
Times cited : (52)

References (80)
  • 1
    • 0242556891 scopus 로고    scopus 로고
    • Toll-like receptors: balancing host resistance with immune tolerance
    • Pasare C., and Medzhitov R. Toll-like receptors: balancing host resistance with immune tolerance. Curr. Opin. Immunol. 15 (2003) 677-682
    • (2003) Curr. Opin. Immunol. , vol.15 , pp. 677-682
    • Pasare, C.1    Medzhitov, R.2
  • 2
    • 20344389060 scopus 로고    scopus 로고
    • Toll-like receptors: linking innate and adaptive immunity
    • Pasare C., and Medzhitov R. Toll-like receptors: linking innate and adaptive immunity. Adv. Exp. Med. Biol. 560 (2005) 11-18
    • (2005) Adv. Exp. Med. Biol. , vol.560 , pp. 11-18
    • Pasare, C.1    Medzhitov, R.2
  • 3
    • 2442484053 scopus 로고    scopus 로고
    • Naturally arising CD4+ regulatory t cells for immunologic self-tolerance and negative control of immune responses
    • Sakaguchi S. Naturally arising CD4+ regulatory t cells for immunologic self-tolerance and negative control of immune responses. Annu. Rev. Immunol. 22 (2004) 531-562
    • (2004) Annu. Rev. Immunol. , vol.22 , pp. 531-562
    • Sakaguchi, S.1
  • 4
    • 20444490383 scopus 로고    scopus 로고
    • Regulation of immunity by self-reactive T cells
    • Kronenberg M., and Rudensky A. Regulation of immunity by self-reactive T cells. Nature 435 (2005) 598-604
    • (2005) Nature , vol.435 , pp. 598-604
    • Kronenberg, M.1    Rudensky, A.2
  • 7
    • 17044430217 scopus 로고    scopus 로고
    • Identifying Foxp3-expressing suppressor T cells with a bicistronic reporter
    • Wan Y.Y., and Flavell R.A. Identifying Foxp3-expressing suppressor T cells with a bicistronic reporter. Proc. Natl. Acad. Sci. U. S. A. 102 (2005) 5126-5131
    • (2005) Proc. Natl. Acad. Sci. U. S. A. , vol.102 , pp. 5126-5131
    • Wan, Y.Y.1    Flavell, R.A.2
  • 11
    • 0021248368 scopus 로고
    • Generation and decay of the immune response to a progressive fibrosarcoma. I. Ly-1+2- suppressor T cells down-regulate the generation of Ly-1-2+ effector T cells
    • North R.J., and Bursuker I. Generation and decay of the immune response to a progressive fibrosarcoma. I. Ly-1+2- suppressor T cells down-regulate the generation of Ly-1-2+ effector T cells. J. Exp. Med. 159 (1984) 1295-1311
    • (1984) J. Exp. Med. , vol.159 , pp. 1295-1311
    • North, R.J.1    Bursuker, I.2
  • 12
    • 0024255820 scopus 로고
    • Immunologically mediated regression of a murine lymphoma after treatment with anti-L3T4 antibody. A consequence of removing L3T4+ suppressor T cells from a host generating predominantly Lyt-2+ T cell-mediated immunity
    • Awwad M., and North R.J. Immunologically mediated regression of a murine lymphoma after treatment with anti-L3T4 antibody. A consequence of removing L3T4+ suppressor T cells from a host generating predominantly Lyt-2+ T cell-mediated immunity. J. Exp. Med. 168 (1988) 2193-2206
    • (1988) J. Exp. Med. , vol.168 , pp. 2193-2206
    • Awwad, M.1    North, R.J.2
  • 13
    • 0020047427 scopus 로고
    • Cyclophosphamide-facilitated adoptive immunotherapy of an established tumor depends on elimination of tumor-induced suppressor T cells
    • North R.J. Cyclophosphamide-facilitated adoptive immunotherapy of an established tumor depends on elimination of tumor-induced suppressor T cells. J. Exp. Med. 155 (1982) 1063-1074
    • (1982) J. Exp. Med. , vol.155 , pp. 1063-1074
    • North, R.J.1
  • 14
    • 0033571105 scopus 로고    scopus 로고
    • Induction of tumor immunity by removing CD25+CD4+ T cells: a common basis between tumor immunity and autoimmunity
    • Shimizu J., Yamazaki S., and Sakaguchi S. Induction of tumor immunity by removing CD25+CD4+ T cells: a common basis between tumor immunity and autoimmunity. J. Immunol. 163 (1999) 5211-5218
    • (1999) J. Immunol. , vol.163 , pp. 5211-5218
    • Shimizu, J.1    Yamazaki, S.2    Sakaguchi, S.3
  • 15
    • 0033168037 scopus 로고    scopus 로고
    • Tumor rejection by in vivo administration of anti-CD25 (interleukin-2 receptor alpha) monoclonal antibody
    • Onizuka S., Tawara I., Shimizu J., Sakaguchi S., Fujita T., and Nakayama E. Tumor rejection by in vivo administration of anti-CD25 (interleukin-2 receptor alpha) monoclonal antibody. Cancer Res. 59 (1999) 3128-3133
    • (1999) Cancer Res. , vol.59 , pp. 3128-3133
    • Onizuka, S.1    Tawara, I.2    Shimizu, J.3    Sakaguchi, S.4    Fujita, T.5    Nakayama, E.6
  • 16
    • 3242736641 scopus 로고    scopus 로고
    • Depletion of CD25+ regulatory cells results in suppression of melanoma growth and induction of autoreactivity in mice
    • Jones E., Dahm-Vicker M., Simon A.K., Green A., Powrie F., Cerundolo V., and Gallimore A. Depletion of CD25+ regulatory cells results in suppression of melanoma growth and induction of autoreactivity in mice. Cancer Immunol. 2 (2002) 1
    • (2002) Cancer Immunol. , vol.2 , pp. 1
    • Jones, E.1    Dahm-Vicker, M.2    Simon, A.K.3    Green, A.4    Powrie, F.5    Cerundolo, V.6    Gallimore, A.7
  • 19
    • 0035903324 scopus 로고    scopus 로고
    • Synergism of cytotoxic T lymphocyte-associated antigen 4 blockade and depletion of CD25(+) regulatory T cells in antitumor therapy reveals alternative pathways for suppression of autoreactive cytotoxic T lymphocyte responses
    • Sutmuller R.P., van Duivenvoorde L.M., van Elsas A., Schumacher T.N., Wildenberg M.E., Allison J.P., Toes R.E., Offringa R., and Melief C.J. Synergism of cytotoxic T lymphocyte-associated antigen 4 blockade and depletion of CD25(+) regulatory T cells in antitumor therapy reveals alternative pathways for suppression of autoreactive cytotoxic T lymphocyte responses. J. Exp. Med. 194 (2001) 823-832
    • (2001) J. Exp. Med. , vol.194 , pp. 823-832
    • Sutmuller, R.P.1    van Duivenvoorde, L.M.2    van Elsas, A.3    Schumacher, T.N.4    Wildenberg, M.E.5    Allison, J.P.6    Toes, R.E.7    Offringa, R.8    Melief, C.J.9
  • 20
    • 0038155128 scopus 로고    scopus 로고
    • Association of increased levels of heavy-chain ferritin with increased CD4+CD25+ regulatory T-Cell levels in patients with melanoma
    • Gray C.P., Arosio P., and Hersey P. Association of increased levels of heavy-chain ferritin with increased CD4+CD25+ regulatory T-Cell levels in patients with melanoma. Clin. Cancer Res. 9 (2003) 2551-2559
    • (2003) Clin. Cancer Res. , vol.9 , pp. 2551-2559
    • Gray, C.P.1    Arosio, P.2    Hersey, P.3
  • 21
    • 28044434385 scopus 로고    scopus 로고
    • Increased population of CD4+CD25 high regulatory T cells with their higher apoptotic and proliferating status in peripheral blood of acute myeloid leukemia patients
    • Wang X., Zheng J., Liu J., Yao J., He Y., Li X., Yu J., Yang J., Liu Z., and Huang S. Increased population of CD4+CD25 high regulatory T cells with their higher apoptotic and proliferating status in peripheral blood of acute myeloid leukemia patients. Eur. J. Haematol. 75 (2005) 468-476
    • (2005) Eur. J. Haematol. , vol.75 , pp. 468-476
    • Wang, X.1    Zheng, J.2    Liu, J.3    Yao, J.4    He, Y.5    Li, X.6    Yu, J.7    Yang, J.8    Liu, Z.9    Huang, S.10
  • 23
    • 0041386189 scopus 로고    scopus 로고
    • + regulatory T cells in patients with gastrointestinal malignancies. Possible involvement of regulatory T cells in disease progression
    • + regulatory T cells in patients with gastrointestinal malignancies. Possible involvement of regulatory T cells in disease progression. Cancer 98 (2003) 1089-1099
    • (2003) Cancer , vol.98 , pp. 1089-1099
    • Sasada, T.1    Kimura, M.2    Yoshida, Y.3    Kanai, M.4    Takabayashi, A.5
  • 27
    • 0141891466 scopus 로고    scopus 로고
    • Increased populations of regulatory T cells in peripheral blood and tumor-infiltrating lymphocytes in patients with gastric and esophageal cancers
    • Ichihara F., Kono K., Takahashi A., Kawaida H., Sugai H., and Fujii H. Increased populations of regulatory T cells in peripheral blood and tumor-infiltrating lymphocytes in patients with gastric and esophageal cancers. Clin. Cancer Res. 9 (2003) 4404-4408
    • (2003) Clin. Cancer Res. , vol.9 , pp. 4404-4408
    • Ichihara, F.1    Kono, K.2    Takahashi, A.3    Kawaida, H.4    Sugai, H.5    Fujii, H.6
  • 28
    • 0036569127 scopus 로고    scopus 로고
    • Cutting edge: regulatory T cells from lung cancer patients directly inhibit autologous T cell proliferation
    • Woo E.Y., Yeh H., Chu C.S., Schlienger K., Carroll R.G., Riley J.L., Kaiser L.R., and June C.H. Cutting edge: regulatory T cells from lung cancer patients directly inhibit autologous T cell proliferation. J. Immunol. 168 (2002) 4272-4276
    • (2002) J. Immunol. , vol.168 , pp. 4272-4276
    • Woo, E.Y.1    Yeh, H.2    Chu, C.S.3    Schlienger, K.4    Carroll, R.G.5    Riley, J.L.6    Kaiser, L.R.7    June, C.H.8
  • 30
    • 13944260193 scopus 로고    scopus 로고
    • Distribution of CD4(+)CD25 high regulatory T-cells in tumor-draining lymph nodes in patients with gastric cancer
    • Kawaida H., Kono K., Takahashi A., Sugai H., Mimura K., Miyagawa N., Omata H., Ooi A., and Fujii H. Distribution of CD4(+)CD25 high regulatory T-cells in tumor-draining lymph nodes in patients with gastric cancer. J. Surg. Res. 124 (2005) 151-157
    • (2005) J. Surg. Res. , vol.124 , pp. 151-157
    • Kawaida, H.1    Kono, K.2    Takahashi, A.3    Sugai, H.4    Mimura, K.5    Miyagawa, N.6    Omata, H.7    Ooi, A.8    Fujii, H.9
  • 31
    • 33646422454 scopus 로고    scopus 로고
    • Intratumoral CD4+CD25+ regulatory T-cell-mediated suppression of infiltrating CD4+ T cells in B-cell non-Hodgkin lymphoma
    • Yang Z.-Z., Novak A.J., Stenson M.J., Witzig T.E., and Ansell S.M. Intratumoral CD4+CD25+ regulatory T-cell-mediated suppression of infiltrating CD4+ T cells in B-cell non-Hodgkin lymphoma. Blood 107 (2006) 3639-3646
    • (2006) Blood , vol.107 , pp. 3639-3646
    • Yang, Z.-Z.1    Novak, A.J.2    Stenson, M.J.3    Witzig, T.E.4    Ansell, S.M.5
  • 32
    • 33646168597 scopus 로고    scopus 로고
    • FOXP3: Of Mice and Men
    • Ziegler S.F. FOXP3: Of Mice and Men. Annu. Rev. Immunol. 24 (2006) 209-226
    • (2006) Annu. Rev. Immunol. , vol.24 , pp. 209-226
    • Ziegler, S.F.1
  • 33
    • 3142737258 scopus 로고    scopus 로고
    • Foxp3 expressing CD4+CD25 high regulatory T cells are overrepresented in human metastatic melanoma lymph nodes and inhibit the function of infiltrating T cells
    • Viguier M., Lemaitre F., Verola O., Cho M.-S., Gorochov G., Dubertret L., Bachelez H., Kourilsky P., and Ferradini L. Foxp3 expressing CD4+CD25 high regulatory T cells are overrepresented in human metastatic melanoma lymph nodes and inhibit the function of infiltrating T cells. J. Immunol. 173 (2004) 1444-1453
    • (2004) J. Immunol. , vol.173 , pp. 1444-1453
    • Viguier, M.1    Lemaitre, F.2    Verola, O.3    Cho, M.-S.4    Gorochov, G.5    Dubertret, L.6    Bachelez, H.7    Kourilsky, P.8    Ferradini, L.9
  • 36
    • 30144436959 scopus 로고    scopus 로고
    • Phenotyping of lymphocytes expressing regulatory and effector markers in infiltrating ductal carcinoma of the breast
    • Leong P.P., Mohammad R., Ibrahim N., Ithnin H., Abdullah M., Davis W.C., and Seow H.F. Phenotyping of lymphocytes expressing regulatory and effector markers in infiltrating ductal carcinoma of the breast. Immunol. Lett. 102 (2006) 229-236
    • (2006) Immunol. Lett. , vol.102 , pp. 229-236
    • Leong, P.P.1    Mohammad, R.2    Ibrahim, N.3    Ithnin, H.4    Abdullah, M.5    Davis, W.C.6    Seow, H.F.7
  • 37
    • 16244409219 scopus 로고    scopus 로고
    • Characteristics of CD4+CD25+ regulatory T cells in the peripheral circulation of patients with head and neck cancer
    • Schaefer C., Kim G.G., Albers A., Hoermann K., Myers E.N., and Whiteside T.L. Characteristics of CD4+CD25+ regulatory T cells in the peripheral circulation of patients with head and neck cancer. Br. J. Cancer 92 (2005) 913-920
    • (2005) Br. J. Cancer , vol.92 , pp. 913-920
    • Schaefer, C.1    Kim, G.G.2    Albers, A.3    Hoermann, K.4    Myers, E.N.5    Whiteside, T.L.6
  • 40
    • 26844577145 scopus 로고    scopus 로고
    • Both regulatory T cells and antitumor effector T cells are primed in the same draining lymph nodes during tumor progression
    • Hiura T., Kagamu H., Miura S., Ishida A., Tanaka H., Tanaka J., Gejyo F., and Yoshizawa H. Both regulatory T cells and antitumor effector T cells are primed in the same draining lymph nodes during tumor progression. J. Immunol. 175 (2005) 5058-5066
    • (2005) J. Immunol. , vol.175 , pp. 5058-5066
    • Hiura, T.1    Kagamu, H.2    Miura, S.3    Ishida, A.4    Tanaka, H.5    Tanaka, J.6    Gejyo, F.7    Yoshizawa, H.8
  • 45
    • 9144219649 scopus 로고    scopus 로고
    • Cutting edge: TGF-beta signaling is required for the in vivo expansion and immunosuppressive capacity of regulatory CD4+CD25+ T cells
    • Huber S., Schramm C., Lehr H.A., Mann A., Schmitt S., Becker C., Protschka M., Galle P.R., Neurath M.F., and Blessing M. Cutting edge: TGF-beta signaling is required for the in vivo expansion and immunosuppressive capacity of regulatory CD4+CD25+ T cells. J. Immunol. 173 (2004) 6526-6531
    • (2004) J. Immunol. , vol.173 , pp. 6526-6531
    • Huber, S.1    Schramm, C.2    Lehr, H.A.3    Mann, A.4    Schmitt, S.5    Becker, C.6    Protschka, M.7    Galle, P.R.8    Neurath, M.F.9    Blessing, M.10
  • 46
    • 1842480959 scopus 로고    scopus 로고
    • TGF-beta regulates in vivo expansion of Foxp3-expressing CD4+CD25+ regulatory T cells responsible for protection against diabetes
    • Peng Y., Laouar Y., Li M.O., Green E.A., and Flavell R.A. TGF-beta regulates in vivo expansion of Foxp3-expressing CD4+CD25+ regulatory T cells responsible for protection against diabetes. Proc. Natl. Acad. Sci. U. S. A. 101 (2004) 4572-4577
    • (2004) Proc. Natl. Acad. Sci. U. S. A. , vol.101 , pp. 4572-4577
    • Peng, Y.1    Laouar, Y.2    Li, M.O.3    Green, E.A.4    Flavell, R.A.5
  • 48
    • 23044463715 scopus 로고    scopus 로고
    • CD4+CD25+ regulatory T cells control the induction of antigen-specific CD4+ helper T cell responses in cancer patients
    • Nishikawa H., Jager E., Ritter G., Old L.J., and Gnjatic S. CD4+CD25+ regulatory T cells control the induction of antigen-specific CD4+ helper T cell responses in cancer patients. Blood 106 (2005) 1008-1011
    • (2005) Blood , vol.106 , pp. 1008-1011
    • Nishikawa, H.1    Jager, E.2    Ritter, G.3    Old, L.J.4    Gnjatic, S.5
  • 49
    • 33646478274 scopus 로고    scopus 로고
    • Influence of CD4+CD25+ regulatory T cells on low/high-avidity CD4+ T cells following peptide vaccination
    • Nishikawa H., Qian F., Tsuji T., Ritter G., Old L.J., Gnjatic S., and Odunsi K. Influence of CD4+CD25+ regulatory T cells on low/high-avidity CD4+ T cells following peptide vaccination. J. Immunol. 176 (2006) 6340-6346
    • (2006) J. Immunol. , vol.176 , pp. 6340-6346
    • Nishikawa, H.1    Qian, F.2    Tsuji, T.3    Ritter, G.4    Old, L.J.5    Gnjatic, S.6    Odunsi, K.7
  • 50
    • 0037243827 scopus 로고    scopus 로고
    • CD4+CD25+ T(R) cells suppress innate immune pathology through cytokine-dependent mechanisms
    • Maloy K.J., Salaun L., Cahill R., Dougan G., Saunders N.J., and Powrie F. CD4+CD25+ T(R) cells suppress innate immune pathology through cytokine-dependent mechanisms. J. Exp. Med. 197 (2003) 111-119
    • (2003) J. Exp. Med. , vol.197 , pp. 111-119
    • Maloy, K.J.1    Salaun, L.2    Cahill, R.3    Dougan, G.4    Saunders, N.J.5    Powrie, F.6
  • 53
    • 16844378685 scopus 로고    scopus 로고
    • Increased populations of regulatory T cells in peripheral blood of patients with hepatocellular carcinoma
    • Ormandy L.A., Hillemann T., Wedemeyer H., Manns M.P., Greten T.F., and Korangy F. Increased populations of regulatory T cells in peripheral blood of patients with hepatocellular carcinoma. Cancer Res. 65 (2005) 2457-2464
    • (2005) Cancer Res. , vol.65 , pp. 2457-2464
    • Ormandy, L.A.1    Hillemann, T.2    Wedemeyer, H.3    Manns, M.P.4    Greten, T.F.5    Korangy, F.6
  • 54
    • 0031647622 scopus 로고    scopus 로고
    • Immunologic self-tolerance maintained by CD25+CD4+ naturally anergic and suppressive T cells: induction of autoimmune disease by breaking their anergic/suppressive state
    • Takahashi T., Kuniyasu Y., Toda M., Sakaguchi N., Itoh M., Iwata M., Shimizu J., and Sakaguchi S. Immunologic self-tolerance maintained by CD25+CD4+ naturally anergic and suppressive T cells: induction of autoimmune disease by breaking their anergic/suppressive state. Int. Immunol. 10 (1998) 1969-1980
    • (1998) Int. Immunol. , vol.10 , pp. 1969-1980
    • Takahashi, T.1    Kuniyasu, Y.2    Toda, M.3    Sakaguchi, N.4    Itoh, M.5    Iwata, M.6    Shimizu, J.7    Sakaguchi, S.8
  • 55
    • 0031821875 scopus 로고    scopus 로고
    • CD4+CD25+ immunoregulatory T cells suppress polyclonal T cell activation in vitro by inhibiting interleukin 2 production
    • Thornton A.M., and Shevach E.M. CD4+CD25+ immunoregulatory T cells suppress polyclonal T cell activation in vitro by inhibiting interleukin 2 production. J. Exp. Med. 188 (1998) 287-296
    • (1998) J. Exp. Med. , vol.188 , pp. 287-296
    • Thornton, A.M.1    Shevach, E.M.2
  • 56
    • 16844362608 scopus 로고    scopus 로고
    • Mechanisms of suppression by suppressor T cells
    • von Boehmer H. Mechanisms of suppression by suppressor T cells. Nat. Immunol. 6 (2005) 338-344
    • (2005) Nat. Immunol. , vol.6 , pp. 338-344
    • von Boehmer, H.1
  • 57
    • 14044257258 scopus 로고    scopus 로고
    • Recognition of a new ARTC1 peptide ligand uniquely expressed in tumor cells by antigen-specific CD4+ regulatory T cells
    • Wang H.Y., Peng G., Guo Z., Shevach E.M., and Wang R.F. Recognition of a new ARTC1 peptide ligand uniquely expressed in tumor cells by antigen-specific CD4+ regulatory T cells. J. Immunol. 174 (2005) 2661-2670
    • (2005) J. Immunol. , vol.174 , pp. 2661-2670
    • Wang, H.Y.1    Peng, G.2    Guo, Z.3    Shevach, E.M.4    Wang, R.F.5
  • 58
    • 1642497640 scopus 로고    scopus 로고
    • Tumor-specific human CD4+ regulatory T cells and their ligands: implications for immunotherapy
    • Wang H.Y., Lee D.A., Peng G., Guo Z., Li Y., Kiniwa Y., Shevach E.M., and Wang R.F. Tumor-specific human CD4+ regulatory T cells and their ligands: implications for immunotherapy. Immunity 20 (2004) 107-118
    • (2004) Immunity , vol.20 , pp. 107-118
    • Wang, H.Y.1    Lee, D.A.2    Peng, G.3    Guo, Z.4    Li, Y.5    Kiniwa, Y.6    Shevach, E.M.7    Wang, R.F.8
  • 59
    • 10844269645 scopus 로고    scopus 로고
    • Dendritic cells loaded with stressed tumor cells elicit long-lasting protective tumor immunity in mice depleted of CD4+CD25+ regulatory T cells
    • Prasad S.J., Farrand K.J., Matthews S.A., Chang J.H., McHugh R.S., and Ronchese F. Dendritic cells loaded with stressed tumor cells elicit long-lasting protective tumor immunity in mice depleted of CD4+CD25+ regulatory T cells. J. Immunol. 174 (2005) 90-98
    • (2005) J. Immunol. , vol.174 , pp. 90-98
    • Prasad, S.J.1    Farrand, K.J.2    Matthews, S.A.3    Chang, J.H.4    McHugh, R.S.5    Ronchese, F.6
  • 60
    • 0036858838 scopus 로고    scopus 로고
    • Depletion of CD25+ regulatory cells uncovers immune responses to shared murine tumor rejection antigens
    • Golgher D., Jones E., Powrie F., Elliott T., and Gallimore A. Depletion of CD25+ regulatory cells uncovers immune responses to shared murine tumor rejection antigens. Eur. J. Immunol. 32 (2002) 3267-3275
    • (2002) Eur. J. Immunol. , vol.32 , pp. 3267-3275
    • Golgher, D.1    Jones, E.2    Powrie, F.3    Elliott, T.4    Gallimore, A.5
  • 61
    • 15444377017 scopus 로고    scopus 로고
    • Intratumor depletion of CD4+ cells unmasks tumor immunogenicity leading to the rejection of late-stage tumors
    • Yu P., Lee Y., Liu W., Krausz T., Chong A., Schreiber H., and Fu Y.X. Intratumor depletion of CD4+ cells unmasks tumor immunogenicity leading to the rejection of late-stage tumors. J. Exp. Med. 201 (2005) 779-791
    • (2005) J. Exp. Med. , vol.201 , pp. 779-791
    • Yu, P.1    Lee, Y.2    Liu, W.3    Krausz, T.4    Chong, A.5    Schreiber, H.6    Fu, Y.X.7
  • 62
    • 33645906878 scopus 로고    scopus 로고
    • Intra-tumoural regulatory T cells: a potential new target in cancer immunotherapy
    • Needham D.J., Lee J.X., and Beilharz M.W. Intra-tumoural regulatory T cells: a potential new target in cancer immunotherapy. Biochem. Biophys. Res. Commun. 343 (2006) 684-691
    • (2006) Biochem. Biophys. Res. Commun. , vol.343 , pp. 684-691
    • Needham, D.J.1    Lee, J.X.2    Beilharz, M.W.3
  • 65
    • 0141688283 scopus 로고    scopus 로고
    • Adoptive-cell-transfer therapy for the treatment of patients with cancer
    • Dudley M.E., and Rosenberg S.A. Adoptive-cell-transfer therapy for the treatment of patients with cancer. Nat. Rev., Cancer 3 (2003) 666-675
    • (2003) Nat. Rev., Cancer , vol.3 , pp. 666-675
    • Dudley, M.E.1    Rosenberg, S.A.2
  • 66
    • 0001776198 scopus 로고    scopus 로고
    • DAB(389)IL-2 (denileukin diftitox, ONTAK): a new fusion protein technology
    • Foss F.M. DAB(389)IL-2 (denileukin diftitox, ONTAK): a new fusion protein technology. Clin. Lymphoma 1 Suppl. 1 (2000) S27-S31
    • (2000) Clin. Lymphoma , vol.1 , Issue.SUPPL. 1
    • Foss, F.M.1
  • 68
    • 27444435581 scopus 로고    scopus 로고
    • Inability of a fusion protein of IL-2 and diphtheria toxin (denileukin diftitox, DAB389IL-2, ONTAK) to eliminate regulatory T lymphocytes in patients with melanoma
    • Attia P., Maker A.V., Haworth L.R., Rogers-Freezer L., and Rosenberg S.A. Inability of a fusion protein of IL-2 and diphtheria toxin (denileukin diftitox, DAB389IL-2, ONTAK) to eliminate regulatory T lymphocytes in patients with melanoma. J. Immunother. 28 (2005) 582-592
    • (2005) J. Immunother. , vol.28 , pp. 582-592
    • Attia, P.1    Maker, A.V.2    Haworth, L.R.3    Rogers-Freezer, L.4    Rosenberg, S.A.5
  • 70
    • 33644784733 scopus 로고    scopus 로고
    • IL-2 administration increases CD4+CD25(hi) Foxp3+ regulatory T cells in cancer patients
    • Ahmadzadeh M., and Rosenberg S.A. IL-2 administration increases CD4+CD25(hi) Foxp3+ regulatory T cells in cancer patients. Blood 107 (2006) 2409-2414
    • (2006) Blood , vol.107 , pp. 2409-2414
    • Ahmadzadeh, M.1    Rosenberg, S.A.2
  • 75
    • 24944551522 scopus 로고    scopus 로고
    • Concurrent induction of antitumor immunity and autoimmune thyroiditis in CD4+CD25+ regulatory T cell-depleted mice
    • Wei W.Z., Jacob J.B., Zielinski J.F., Flynn J.C., Shim K.D., Alsharabi G., Giraldo A.A., and Kong Y.C. Concurrent induction of antitumor immunity and autoimmune thyroiditis in CD4+CD25+ regulatory T cell-depleted mice. Cancer Res. 65 (2005) 8471-8478
    • (2005) Cancer Res. , vol.65 , pp. 8471-8478
    • Wei, W.Z.1    Jacob, J.B.2    Zielinski, J.F.3    Flynn, J.C.4    Shim, K.D.5    Alsharabi, G.6    Giraldo, A.A.7    Kong, Y.C.8
  • 77
    • 4644335311 scopus 로고    scopus 로고
    • Cancer: an inflammatory link
    • Balkwill F., and Coussens L.M. Cancer: an inflammatory link. Nature 431 (2004) 405-406
    • (2004) Nature , vol.431 , pp. 405-406
    • Balkwill, F.1    Coussens, L.M.2
  • 79
    • 20144375359 scopus 로고    scopus 로고
    • CD4+CD25+ regulatory lymphocytes induce regression of intestinal tumors in ApcMin/+mice
    • Erdman S.E., Sohn J.J., Rao V.P., Nambiar P.R., Ge Z., Fox J.G., and Schauer D.B. CD4+CD25+ regulatory lymphocytes induce regression of intestinal tumors in ApcMin/+mice. Cancer Res. 65 (2005) 3998-4004
    • (2005) Cancer Res. , vol.65 , pp. 3998-4004
    • Erdman, S.E.1    Sohn, J.J.2    Rao, V.P.3    Nambiar, P.R.4    Ge, Z.5    Fox, J.G.6    Schauer, D.B.7
  • 80
    • 20444464066 scopus 로고    scopus 로고
    • Tumor cyclooxygenase-2/prostaglandin E2-dependent promotion of FOXP3 expression and CD4+CD25+ T regulatory cell activities in lung cancer
    • Sharma S., Yang S.C., Zhu L., Reckamp K., Gardner B., Baratelli F., Huang M., Batra R.K., and Dubinett S.M. Tumor cyclooxygenase-2/prostaglandin E2-dependent promotion of FOXP3 expression and CD4+CD25+ T regulatory cell activities in lung cancer. Cancer Res. 65 (2005) 5211-5220
    • (2005) Cancer Res. , vol.65 , pp. 5211-5220
    • Sharma, S.1    Yang, S.C.2    Zhu, L.3    Reckamp, K.4    Gardner, B.5    Baratelli, F.6    Huang, M.7    Batra, R.K.8    Dubinett, S.M.9


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.