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Volumn 3, Issue 9, 2003, Pages 666-675

Adoptive-cell-transfer therapy for the treatment of patients with cancer

Author keywords

[No Author keywords available]

Indexed keywords

ANTIGEN; CD3 ANTIGEN; CD8 ANTIGEN; MELANOCYTE DIFFERENTIATION ANTIGEN; MELANOMA ANTIGEN; OKT 3; T LYMPHOCYTE RECEPTOR; TUMOR ANTIGEN; UNCLASSIFIED DRUG; VIRUS ANTIGEN;

EID: 0141688283     PISSN: 1474175X     EISSN: None     Source Type: Journal    
DOI: 10.1038/nrc1167     Document Type: Review
Times cited : (559)

References (97)
  • 1
    • 0036218697 scopus 로고    scopus 로고
    • Producing nature's gene-chips: The generation of peptides for display by MHC class I molecules
    • Shastri, N., Schwab, S. & Serwold, T. Producing nature's gene-chips: the generation of peptides for display by MHC class I molecules. Annu. Rev. Immunol. 20, 463-493 (2002).
    • (2002) Annu. Rev. Immunol. , vol.20 , pp. 463-493
    • Shastri, N.1    Schwab, S.2    Serwold, T.3
  • 3
    • 0029669950 scopus 로고    scopus 로고
    • A mutated beta-catenin gene encodes a melanoma-specific antigen recognized by tumor infiltrating lymphocytes
    • Robbins, P. F. et al. A mutated beta-catenin gene encodes a melanoma-specific antigen recognized by tumor infiltrating lymphocytes. J. Exp. Med. 183, 1185-1192 (1996).
    • (1996) J. Exp. Med. , vol.183 , pp. 1185-1192
    • Robbins, P.F.1
  • 4
    • 2642683198 scopus 로고    scopus 로고
    • Simultaneous humoral and cellular immune response against cancer-testis antigen NY-ESO-1: Definition of human histocompatibility leukocyte antigen (HLA)-A2-binding peptide epitopes
    • Jager, E. et al. Simultaneous humoral and cellular immune response against cancer-testis antigen NY-ESO-1: definition of human histocompatibility leukocyte antigen (HLA)-A2-binding peptide epitopes. J. Exp. Med. 187, 265-270 (1998).
    • (1998) J. Exp. Med. , vol.187 , pp. 265-270
    • Jager, E.1
  • 5
    • 0028302028 scopus 로고
    • Identification of the immunodominant peptides of the MART-1 human melanoma antigen recognized by the majority of HLA-A2-restricted tumor infiltrating lymphocytes
    • Kawakami, Y. et al. Identification of the immunodominant peptides of the MART-1 human melanoma antigen recognized by the majority of HLA-A2-restricted tumor infiltrating lymphocytes. J. Exp. Med. 180, 347-352 (1994).
    • (1994) J. Exp. Med. , vol.180 , pp. 347-352
    • Kawakami, Y.1
  • 6
    • 14844341146 scopus 로고
    • Recognition of multiple epitopes in the human melanoma antigen gp100 by tumor-infiltrating T lymphocytes associated with in vivo tumor regression
    • Kawakami, Y. et al. Recognition of multiple epitopes in the human melanoma antigen gp100 by tumor-infiltrating T lymphocytes associated with in vivo tumor regression. J. Immunol. 154, 3961-3968 (1995).
    • (1995) J. Immunol. , vol.154 , pp. 3961-3968
    • Kawakami, Y.1
  • 7
    • 0035062597 scopus 로고    scopus 로고
    • Noncytolytic control of viral infections by the innate and adaptive immune response
    • Guidotti, L. G. & Chisari, F. V. Noncytolytic control of viral infections by the innate and adaptive immune response. Annu. Rev. Immunol. 19, 65-91 (2001).
    • (2001) Annu. Rev. Immunol. , vol.19 , pp. 65-91
    • Guidotti, L.G.1    Chisari, F.V.2
  • 9
    • 0031890206 scopus 로고    scopus 로고
    • Immunologic and therapeutic evaluation of a synthetic peptide vaccine for the treatment of patients with metastatic melanoma
    • Rosenberg, S. A. et al. Immunologic and therapeutic evaluation of a synthetic peptide vaccine for the treatment of patients with metastatic melanoma. Nature Med. 4, 321-327 (1998).
    • (1998) Nature Med. , vol.4 , pp. 321-327
    • Rosenberg, S.A.1
  • 10
    • 0037217054 scopus 로고    scopus 로고
    • Granulocyte-macrophage-colony-stimulating factor added to a multipeptide vaccine for resected Stage II melanoma
    • Weber, J. et al. Granulocyte-macrophage-colony-stimulating factor added to a multipeptide vaccine for resected Stage II melanoma. Cancer 97, 186-200 (2003).
    • (2003) Cancer , vol.97 , pp. 186-200
    • Weber, J.1
  • 11
    • 0030807565 scopus 로고    scopus 로고
    • Antigenic cancer cells grow progressively in immune hosts without evidence for T cell exhaustion or systemic anergy
    • Wick, M. et al. Antigenic cancer cells grow progressively in immune hosts without evidence for T cell exhaustion or systemic anergy. J. Exp. Med. 186, 229-238 (1997).
    • (1997) J. Exp. Med. , vol.186 , pp. 229-238
    • Wick, M.1
  • 12
    • 0032169195 scopus 로고    scopus 로고
    • Tumor-infiltrating lymphocytes exhibiting high ex vivo cytolytic activity fail to prevent murine melanoma tumor growth in vivo
    • Prevost-Blondel, A. et al. Tumor-infiltrating lymphocytes exhibiting high ex vivo cytolytic activity fail to prevent murine melanoma tumor growth in vivo. J. Immunol. 161, 2187-2194 (1998).
    • (1998) J. Immunol. , vol.161 , pp. 2187-2194
    • Prevost-Blondel, A.1
  • 13
    • 0035963379 scopus 로고    scopus 로고
    • Roles of tumour localization, second signals and cross priming in cytotoxic T-cell induction
    • Ochsenbein, A. F. et al. Roles of tumour localization, second signals and cross priming in cytotoxic T-cell induction. Nature 411, 1058-1064 (2001).
    • (2001) Nature , vol.411 , pp. 1058-1064
    • Ochsenbein, A.F.1
  • 14
    • 0037066427 scopus 로고    scopus 로고
    • The danger model: A renewed sense of self
    • Matzinger, P. The danger model: a renewed sense of self. Science 296, 301-305 (2002).
    • (2002) Science , vol.296 , pp. 301-305
    • Matzinger, P.1
  • 15
    • 0036597371 scopus 로고    scopus 로고
    • + suppressor T cells: More questions than answers
    • + suppressor T cells: more questions than answers. Nature Rev. Immunol. 2, 389-400 (2002).
    • (2002) Nature Rev. Immunol. , vol.2 , pp. 389-400
    • Shevach, E.M.1
  • 16
    • 0033571105 scopus 로고    scopus 로고
    • + T cells: A common basis between tumor immunity and autoimmunity
    • + T cells: a common basis between tumor immunity and autoimmunity. J. Immunol. 183, 5211-5218 (1999).
    • (1999) J. Immunol. , vol.183 , pp. 5211-5218
    • Shimizu, J.1    Yamazaki, S.2    Sakaguchi, S.3
  • 17
    • 0036852191 scopus 로고    scopus 로고
    • Natural selection of tumor variants in the generation of 'tumor escape' phenotypes
    • Khong, H. T. & Restifo, N. P. Natural selection of tumor variants in the generation of 'tumor escape' phenotypes. Nature Immunol. 3, 999-1005 (2002).
    • (2002) Nature Immunol. , vol.3 , pp. 999-1005
    • Khong, H.T.1    Restifo, N.P.2
  • 18
    • 0037174674 scopus 로고    scopus 로고
    • Cancer regression and autoimmunity in patients after clonal repopulation with antitumor lymphocytes
    • Dudley, M. E. et al. Cancer regression and autoimmunity in patients after clonal repopulation with antitumor lymphocytes. Science 298, 850-854 (2002). This report describes adoptive cell transfer with TILs following non-myeloablative chemotherapy for treatment of patients with melanoma, and represents the first successful use of this combination therapy for the treatment of solid malignancy in patients.
    • (2002) Science , vol.298 , pp. 850-854
    • Dudley, M.E.1
  • 19
    • 0032170108 scopus 로고    scopus 로고
    • Infusion of cytotoxic T cells for the prevention and treatment of Epstein-Barr virus-induced lymphoma in allogeneic transplant recipients
    • Rooney, C. M. et al. Infusion of cytotoxic T cells for the prevention and treatment of Epstein-Barr virus-induced lymphoma in allogeneic transplant recipients. Blood 92, 1549-1555 (1998). This paper describes the generation and clinical use of lymphocyte cultures for ACT therapy of patients with metastatic cancer.
    • (1998) Blood , vol.92 , pp. 1549-1555
    • Rooney, C.M.1
  • 20
    • 0031852722 scopus 로고    scopus 로고
    • gp100/pmel 17 is a murine tumor rejection antigen: Induction of 'self'-reactive, tumoricidal T cells using high-affinity, altered peptide ligand
    • Overwijk, W. W. et al. gp100/pmel 17 is a murine tumor rejection antigen: induction of 'self'-reactive, tumoricidal T cells using high-affinity, altered peptide ligand. J. Exp. Med. 188, 277-286 (1998). Demonstration in an animal model that immune manipulation can result in efficacious tumour treatments mediated through unmutated melanocyte-differentiation antigens.
    • (1998) J. Exp. Med. , vol.188 , pp. 277-286
    • Overwijk, W.W.1
  • 21
    • 0025330385 scopus 로고
    • Phenotype analyses and cellular mechanisms of the pre-effector T-lymphocyte response to a progressive syngeneic murine sarcoma
    • Sakai, K., Chang, A. E. & Shu, S. Y. Phenotype analyses and cellular mechanisms of the pre-effector T-lymphocyte response to a progressive syngeneic murine sarcoma. Cancer Res. 50, 4371-4376 (1990).
    • (1990) Cancer Res. , vol.50 , pp. 4371-4376
    • Sakai, K.1    Chang, A.E.2    Shu, S.Y.3
  • 23
    • 0027412082 scopus 로고
    • Clinical observations on adoptive immunotherapy with vaccine-primed T- lymphocytes secondarily sensitized to tumor in vitro
    • Chang, A. E. et al. Clinical observations on adoptive immunotherapy with vaccine-primed T- lymphocytes secondarily sensitized to tumor in vitro. Cancer Res. 53, 1043-1050 (1993).
    • (1993) Cancer Res. , vol.53 , pp. 1043-1050
    • Chang, A.E.1
  • 24
    • 0031586038 scopus 로고    scopus 로고
    • Treatment of subcutaneous tumor with adoptively transferred T cells
    • Peng, L., Shu, S. & Krauss, J. C. Treatment of subcutaneous tumor with adoptively transferred T cells. Cell Immunol. 178, 24-32 (1997).
    • (1997) Cell Immunol. , vol.178 , pp. 24-32
    • Peng, L.1    Shu, S.2    Krauss, J.C.3
  • 25
    • 0033556322 scopus 로고    scopus 로고
    • High avidity CTLs for two self-antigens demonstrate superior in vitro and in vivo antitumor efficacy
    • Zeh, H. J. 3rd, Perry-Lalley, D., Dudley, M. E., Rosenberg, S. A., & Yang, J. C. High avidity CTLs for two self-antigens demonstrate superior in vitro and in vivo antitumor efficacy. J. Immunol. 162, 980-994 (1999).
    • (1999) J. Immunol. , vol.162 , pp. 980-994
    • Zeh H.J. III1    Perry-Lalley, D.2    Dudley, M.E.3    Rosenberg, S.A.4    Yang, J.C.5
  • 26
    • 0029588539 scopus 로고
    • Tumor-specific granulocyte/macrophage colony-stimulating factor and interferon gamma secretion is associated with in vivo therapeutic efficacy of activated tumor-draining lymph node cells
    • Aruga, A., Shu, S. & Chang, A. E. Tumor-specific granulocyte/macrophage colony-stimulating factor and interferon gamma secretion is associated with in vivo therapeutic efficacy of activated tumor-draining lymph node cells. Cancer Immunol. Immunother. 41, 317-324 (1995).
    • (1995) Cancer Immunol. Immunother. , vol.41 , pp. 317-324
    • Aruga, A.1    Shu, S.2    Chang, A.E.3
  • 28
    • 0025058972 scopus 로고
    • Synergistic antitumor activity of tumor-infiltrating lymphocytes, interleukin 2, and local tumor irradiation. Studies on the mechanism of action
    • Cameron, R. B., Spiess, P. J. & Rosenberg, S. A. Synergistic antitumor activity of tumor-infiltrating lymphocytes, interleukin 2, and local tumor irradiation. Studies on the mechanism of action. J. Exp. Med. 171, 249-263 (1990).
    • (1990) J. Exp. Med. , vol.171 , pp. 249-263
    • Cameron, R.B.1    Spiess, P.J.2    Rosenberg, S.A.3
  • 29
    • 0020031140 scopus 로고
    • Augmentation of the anti-tumor therapeutic efficacy of long-term cultured T lymphocytes by in vivo administration of purified interleukin 2
    • Cheever, M. A., Greenberg, P. D., Fefer, A. & Gillis, S. Augmentation of the anti-tumor therapeutic efficacy of long-term cultured T lymphocytes by in vivo administration of purified interleukin 2. J. Exp. Med. 155, 968-980 (1982).
    • (1982) J. Exp. Med. , vol.155 , pp. 968-980
    • Cheever, M.A.1    Greenberg, P.D.2    Fefer, A.3    Gillis, S.4
  • 30
    • 0023693877 scopus 로고
    • Adoptive immunotherapy of microscopic and advanced visceral metastases with in vitro sensitized lymphoid cells from mice bearing progressive tumors
    • Chou, T., Bertera, S., Chang, A. E. & Shu, S. Adoptive immunotherapy of microscopic and advanced visceral metastases with in vitro sensitized lymphoid cells from mice bearing progressive tumors. J. Immunol. 141, 1775-1781 (1988).
    • (1988) J. Immunol. , vol.141 , pp. 1775-1781
    • Chou, T.1    Bertera, S.2    Chang, A.E.3    Shu, S.4
  • 31
    • 0022473607 scopus 로고
    • A new approach to the adoptive immunotherapy of cancer with tumor-infiltrating lymphocytes
    • Rosenberg, S. A., Spiess, P. & Lafreniere, R. A new approach to the adoptive immunotherapy of cancer with tumor-infiltrating lymphocytes. Science 233, 1318-1321 (1986). This seminal paper describes the use of TILs, together with cyclophosphamide conditioning, to treat advanced tumours in mice.
    • (1986) Science , vol.233 , pp. 1318-1321
    • Rosenberg, S.A.1    Spiess, P.2    Lafreniere, R.3
  • 32
    • 0033603008 scopus 로고    scopus 로고
    • Persistence, immune specificity, and functional ability of murine mutant ras epitope-specific CD4(+) and CD8(+) T lymphocytes following in vivo adoptive transfer
    • Bristol, J. A., Schlom, J. & Abrams, S. I. Persistence, immune specificity, and functional ability of murine mutant ras epitope-specific CD4(+) and CD8(+) T lymphocytes following in vivo adoptive transfer. Cell Immunol. 194, 78-89 (1999).
    • (1999) Cell Immunol. , vol.194 , pp. 78-89
    • Bristol, J.A.1    Schlom, J.2    Abrams, S.I.3
  • 35
    • 0016531488 scopus 로고
    • Syngeneic adoptive immunotherapy and chemoimmunotherapy of a Friend leukemia: Requirement for T cells
    • Berenson, J. R., Einstein, A. B. Jr & Fefer, A. Syngeneic adoptive immunotherapy and chemoimmunotherapy of a Friend leukemia: requirement for T cells. J. Immunol. 115, 234-238 (1975).
    • (1975) J. Immunol. , vol.115 , pp. 234-238
    • Berenson, J.R.1    Einstein A.B., Jr.2    Fefer, A.3
  • 36
    • 0018934336 scopus 로고
    • Specificity of adoptive chemoimmunotherapy of established syngeneic tumors
    • Cheever, M. A., Greenberg, P. D. & Fefer, A. Specificity of adoptive chemoimmunotherapy of established syngeneic tumors. J. Immunol. 125, 711-714 (1980).
    • (1980) J. Immunol. , vol.125 , pp. 711-714
    • Cheever, M.A.1    Greenberg, P.D.2    Fefer, A.3
  • 37
    • 0020047427 scopus 로고
    • Cyclophosphamide-facilitated adoptive immunotherapy of an established tumor depends on elimination of tumor-induced suppressor T cells
    • North, R. J. Cyclophosphamide-facilitated adoptive immunotherapy of an established tumor depends on elimination of tumor-induced suppressor T cells. J. Exp. Med. 155, 1063-1074 (1982).
    • (1982) J. Exp. Med. , vol.155 , pp. 1063-1074
    • North, R.J.1
  • 38
    • 0036530234 scopus 로고    scopus 로고
    • Infusion of autologous Epstein-Barr virus (EBV)-specific cytotoxic T cells for prevention of EBV-related lymphoproliferative disorder in solid organ transplant recipients with evidence of active virus replication
    • Cornoli, P. et al. Infusion of autologous Epstein-Barr virus (EBV)-specific cytotoxic T cells for prevention of EBV-related lymphoproliferative disorder in solid organ transplant recipients with evidence of active virus replication. Blood 99, 2592-2598 (2002).
    • (2002) Blood , vol.99 , pp. 2592-2598
    • Cornoli, P.1
  • 39
    • 0037055714 scopus 로고    scopus 로고
    • Treatment of Epstein-Barr-virus-positive post-transplantation lymphoproliferative disease with partly HLA-matched allogeneic cytotoxic T cells
    • Haque, T. et al. Treatment of Epstein-Barr-virus-positive post-transplantation lymphoproliferative disease with partly HLA-matched allogeneic cytotoxic T cells. Lancet 360, 436-442 (2002).
    • (2002) Lancet , vol.360 , pp. 436-442
    • Haque, T.1
  • 40
    • 0030873733 scopus 로고    scopus 로고
    • Biology and adoptive cell therapy of Epstein-Barr virus-associated lymphoproliferative disorders in recipients of marrow allografts
    • O'Reilly, R. J. et al. Biology and adoptive cell therapy of Epstein-Barr virus-associated lymphoproliferative disorders in recipients of marrow allografts. Immunol. Rev. 157, 195-216 (1997).
    • (1997) Immunol. Rev. , vol.157 , pp. 195-216
    • O'Reilly, R.J.1
  • 41
    • 0029915469 scopus 로고    scopus 로고
    • The development of cellular immunity to Epstein-Barr virus after allogeneic bone marrow transplantation
    • Lucas, K. G., Small, T. N., Heller, G., Dupont, B. & O'Reilly, R. J. The development of cellular immunity to Epstein-Barr virus after allogeneic bone marrow transplantation. Blood 87, 2594-2603 (1996).
    • (1996) Blood , vol.87 , pp. 2594-2603
    • Lucas, K.G.1    Small, T.N.2    Heller, G.3    Dupont, B.4    O'Reilly, R.J.5
  • 42
    • 0019951384 scopus 로고
    • Lymphokine-activated killer cell phenomenon. Lysis of natural killer-resistant fresh solid tumor cells by interleukin 2-activated autologous human peripheral blood lymphocytes
    • Grimm, E. A., Mazumder, A., Zhang, H. Z. & Rosenberg, S. A. Lymphokine-activated killer cell phenomenon. Lysis of natural killer-resistant fresh solid tumor cells by interleukin 2-activated autologous human peripheral blood lymphocytes. J. Exp. Med. 155, 1823-1841 (1982).
    • (1982) J. Exp. Med. , vol.155 , pp. 1823-1841
    • Grimm, E.A.1    Mazumder, A.2    Zhang, H.Z.3    Rosenberg, S.A.4
  • 43
    • 0021170244 scopus 로고
    • Adoptive immunotherapy of established pulmonary metastases with LAK cells and recombinant interleukin-2
    • Mule, J. J., Shu, S., Schwarz, S. L. & Rosenberg, S. A. Adoptive immunotherapy of established pulmonary metastases with LAK cells and recombinant interleukin-2. Science 225, 1487-1489 (1984).
    • (1984) Science , vol.225 , pp. 1487-1489
    • Mule, J.J.1    Shu, S.2    Schwarz, S.L.3    Rosenberg, S.A.4
  • 44
    • 0022349817 scopus 로고
    • Observations on the systemic administration of autologous lymphokine-activated killer cells and recombinant interleukin-2 to patients with metastatic cancer
    • Rosenberg, S. A. et al. Observations on the systemic administration of autologous lymphokine-activated killer cells and recombinant interleukin-2 to patients with metastatic cancer. N. Engl. J. Med. 313, 1485-1492 (1985).
    • (1985) N. Engl. J. Med. , vol.313 , pp. 1485-1492
    • Rosenberg, S.A.1
  • 45
    • 0034759775 scopus 로고    scopus 로고
    • Immune modulation in cancer patients after adoptive transfer of anti-CD3/anti-CD28-costimulated T cells-phase I clinical trial
    • Lum, L. G., LeFever, A. V., Treisman, J. S. Garlie, N. K. & Hanson J. P. Jr. Immune modulation in cancer patients after adoptive transfer of anti-CD3/anti-CD28-costimulated T cells-phase I clinical trial. J. Immunother. 24, 408-419 (2001).
    • (2001) J. Immunother. , vol.24 , pp. 408-419
    • Lum, L.G.1    LeFever, A.V.2    Treisman, J.S.3    Garlie, N.K.4    Hanson J.P., Jr.5
  • 46
    • 0031928111 scopus 로고    scopus 로고
    • + T cells, infusional interleukin-2, and cyclophosphamide in patients with advanced cancer
    • + T cells, infusional interleukin-2, and cyclophosphamide in patients with advanced cancer. J. Clin. Oncol. 16, 2752-2760 (1998).
    • (1998) J. Clin. Oncol. , vol.16 , pp. 2752-2760
    • Curti, B.D.1
  • 47
    • 0033168462 scopus 로고    scopus 로고
    • Cellular immunotherapy for patients with metastatic colorectal carcinoma using lymph node lymphocytes localized in vivo by radiolabeled monoclonal antibody
    • Kim, J. A. et al. Cellular immunotherapy for patients with metastatic colorectal carcinoma using lymph node lymphocytes localized in vivo by radiolabeled monoclonal antibody. Cancer 86, 22-30 (1999).
    • (1999) Cancer , vol.86 , pp. 22-30
    • Kim, J.A.1
  • 48
    • 0027529476 scopus 로고
    • Prospective randomized trial of high-dose interleukin-2 alone or in conjunction with lymphokine-activated killer cells for the treatment of patients with advanced cancer
    • Rosenberg, S. A. et al. Prospective randomized trial of high-dose interleukin-2 alone or in conjunction with lymphokine-activated killer cells for the treatment of patients with advanced cancer. J. Natl Cancer Inst. 85, 622-632 (1993).
    • (1993) J. Natl Cancer Inst. , vol.85 , pp. 622-632
    • Rosenberg, S.A.1
  • 49
    • 0037365973 scopus 로고    scopus 로고
    • Phase II trial of autologous tumor vaccination, anti-CD3-activated vaccine-primed lymphocytes, and interleukin-2 in stage IV renal cell cancer
    • Chang, A. E. et al. Phase II trial of autologous tumor vaccination, anti-CD3-activated vaccine-primed lymphocytes, and interleukin-2 in stage IV renal cell cancer. J. Clin. Oncol. 21, 884-890 (2003).
    • (2003) J. Clin. Oncol. , vol.21 , pp. 884-890
    • Chang, A.E.1
  • 50
    • 0033776411 scopus 로고    scopus 로고
    • Systemic adoptive T-cell immunotherapy in recurrent and metastatic carcinoma of the head and neck: A phase 1 study
    • To, W. C. et al. Systemic adoptive T-cell immunotherapy in recurrent and metastatic carcinoma of the head and neck: a phase 1 study. Arch. Otolaryngol. Head Neck Surg. 126, 1225-1231 (2000).
    • (2000) Arch. Otolaryngol. Head Neck Surg. , vol.126 , pp. 1225-1231
    • To, W.C.1
  • 51
    • 0032859879 scopus 로고    scopus 로고
    • T-cell adoptive immunotherapy of metastatic renal cell carcinoma
    • Plautz, G.E. et al. T-cell adoptive immunotherapy of metastatic renal cell carcinoma. Urology 54, 617-623 (1999).
    • (1999) Urology , vol.54 , pp. 617-623
    • Plautz, G.E.1
  • 52
    • 0035990419 scopus 로고    scopus 로고
    • Adoptive cellular therapy with tumor vaccine draining lymph node lymphocytes after vaccination with HLA-B7/beta2-microglobulin gene-modified autologous tumor cells
    • Meijer, S. L. et al. Adoptive cellular therapy with tumor vaccine draining lymph node lymphocytes after vaccination with HLA-B7/beta2-microglobulin gene-modified autologous tumor cells. J. Immunother. 25, 359-372 (2002).
    • (2002) J. Immunother. , vol.25 , pp. 359-372
    • Meijer, S.L.1
  • 53
    • 0037442228 scopus 로고    scopus 로고
    • Survival and tumor localization of adoptively transferred melan-a-specific T cells in melanoma patients
    • Meidenbauer, N. et al. Survival and tumor localization of adoptively transferred melan-a-specific T cells in melanoma patients. J. Immunol. 170, 2161-2169 (2003).
    • (2003) J. Immunol. , vol.170 , pp. 2161-2169
    • Meidenbauer, N.1
  • 54
    • 0036171757 scopus 로고    scopus 로고
    • Ex vivo expansion of polyclonal and antigen-specific cytotoxic T lymphocytes by artificial APCs expressing ligands for the T-cell receptor, CD28 and 4-1 BB
    • Maus, M. V. et al. Ex vivo expansion of polyclonal and antigen-specific cytotoxic T lymphocytes by artificial APCs expressing ligands for the T-cell receptor, CD28 and 4-1 BB. Nature Bictechnol. 20, 143-148 (2002).
    • (2002) Nature Bictechnol. , vol.20 , pp. 143-148
    • Maus, M.V.1
  • 55
    • 0036909464 scopus 로고    scopus 로고
    • A cell-based artificial antigen-presenting cell coated with anti-CD3 and CD28 antibodies enables rapid expansion and long-term growth of CD4 T lymphocytes
    • Thomas, A. K., Maus, M. V., Shalaby, W. S., June, C. H. & Riley, J. L. A cell-based artificial antigen-presenting cell coated with anti-CD3 and CD28 antibodies enables rapid expansion and long-term growth of CD4 T lymphocytes. Clin. Immunol. 105, 259-272 (2002).
    • (2002) Clin. Immunol. , vol.105 , pp. 259-272
    • Thomas, A.K.1    Maus, M.V.2    Shalaby, W.S.3    June, C.H.4    Riley, J.L.5
  • 56
    • 0038587735 scopus 로고    scopus 로고
    • Ex vivo induction and expansion of antigen-specific cytotoxic T cells by HLA-Ig-coated artificial antigen-presenting cells
    • Oelke, M. et al. Ex vivo induction and expansion of antigen-specific cytotoxic T cells by HLA-Ig-coated artificial antigen-presenting cells. Nature Med. 9, 619-624 (2003).
    • (2003) Nature Med. , vol.9 , pp. 619-624
    • Oelke, M.1
  • 57
    • 0037500890 scopus 로고    scopus 로고
    • Large-scale expansion of dendritic cell-primed polyclonal human cytotoxic T-lymphocyte lines using lymphoblastoid cell lines for adoptive immunotherapy
    • Sili, U. et al. Large-scale expansion of dendritic cell-primed polyclonal human cytotoxic T-lymphocyte lines using lymphoblastoid cell lines for adoptive immunotherapy. J. Immunother. 26, 241-256 (2003).
    • (2003) J. Immunother. , vol.26 , pp. 241-256
    • Sili, U.1
  • 58
    • 0028820386 scopus 로고
    • Reconstitution of cellular immunity against cytomegalovirus in recipients of allogeneic bone marrow by transfer of T-cell clones from the donor
    • Walter, E. A. et al. Reconstitution of cellular immunity against cytomegalovirus in recipients of allogeneic bone marrow by transfer of T-cell clones from the donor. N. Engl. J. Med. 333, 1038-1044 (1995). This influential paper describes the use of CMV-specific cloned lymphocytes for the treatment of bone-marrow-transplant recipients, and their efficacy in prevention of CMV-induced disease.
    • (1995) N. Engl. J. Med. , vol.333 , pp. 1038-1044
    • Walter, E.A.1
  • 59
    • 17944379652 scopus 로고    scopus 로고
    • Adoptive transfer of cloned melanoma-reactive T lymphocytes for the treatment of patients with metastatic melanoma
    • Dudley, M. E. et al. Adoptive transfer of cloned melanoma-reactive T lymphocytes for the treatment of patients with metastatic melanoma. J. Immunother. 24, 363-373 (2001).
    • (2001) J. Immunother. , vol.24 , pp. 363-373
    • Dudley, M.E.1
  • 60
    • 18344362786 scopus 로고    scopus 로고
    • A phase I study of nonmyeloablative chemotherapy and adoptive transfer of autologous tumor antigen-specific T lymphocytes in patients with metastatic melanoma
    • Dudley, M. E. et al. A phase I study of nonmyeloablative chemotherapy and adoptive transfer of autologous tumor antigen-specific T lymphocytes in patients with metastatic melanoma. J. Immunother. 25, 243-251 (2002). The failure of non-myeloablative chemotherapy followed by administration of highly avid T-cell clones for treatment of patients with melanoma is documented.
    • (2002) J. Immunother. , vol.25 , pp. 243-251
    • Dudley, M.E.1
  • 61
    • 0037058993 scopus 로고    scopus 로고
    • Adoptive T cell therapy using antigen-specific CD8+ T cell clones for the treatment of patients with metastatic melanoma: In vivo persistence, migration, and antitumor effect of transferred T cells
    • Yee, C. et al. Adoptive T cell therapy using antigen-specific CD8+ T cell clones for the treatment of patients with metastatic melanoma: in vivo persistence, migration, and antitumor effect of transferred T cells. Proc. Natl Acad. Sci. USA 99, 16168-16173 (2002). An excellent example of the failure of highly avid T-cell clones to induce objective clinical responses in patients with metastatic solid tumours. T-cell function, transport and persistence were monitored.
    • (2002) Proc. Natl Acad. Sci. USA , vol.99 , pp. 16168-16173
    • Yee, C.1
  • 62
    • 0033105536 scopus 로고    scopus 로고
    • Rapid death of adoptively transferred T cells in acquired immunodeficiency syndrome
    • Tan, R. et al. Rapid death of adoptively transferred T cells in acquired immunodeficiency syndrome. Blood 93, 1506-1510 (1999).
    • (1999) Blood , vol.93 , pp. 1506-1510
    • Tan, R.1
  • 63
    • 0032973455 scopus 로고    scopus 로고
    • In vivo migration and function of transferred HIV-1-specific cytotoxic T cells
    • Brodie, S. J. et al. in vivo migration and function of transferred HIV-1-specific cytotoxic T cells. Nature Med. 5, 34-41 (1999).
    • (1999) Nature Med. , vol.5 , pp. 34-41
    • Brodie, S.J.1
  • 64
    • 0034541167 scopus 로고    scopus 로고
    • + T cells have a major 'post-licensing' role in CTL mediated anti-tumor immunity
    • + T cells have a major 'post-licensing' role in CTL mediated anti-tumor immunity. J. Immunol. 165, 6047-6055 (2000).
    • (2000) J. Immunol. , vol.165 , pp. 6047-6055
    • Marzo, A.L.1
  • 65
    • 0035135082 scopus 로고    scopus 로고
    • Persistence of immunogenic pulmonary metastases in the presence of protective anti-melanoma immunity
    • Donawho, C. K., Pride, M. W. & Kripke, M. L. Persistence of immunogenic pulmonary metastases in the presence of protective anti-melanoma immunity. Cancer Res. 61, 215-221 (2001).
    • (2001) Cancer Res. , vol.61 , pp. 215-221
    • Donawho, C.K.1    Pride, M.W.2    Kripke, M.L.3
  • 66
    • 0023934650 scopus 로고
    • Immunotherapy of patients with advanced cancer using tumor-infiltrating lymphocytes and recombinant interleukin-2: A pilot study
    • Topalian, S. L. et al. Immunotherapy of patients with advanced cancer using tumor-infiltrating lymphocytes and recombinant interleukin-2: a pilot study. J. Clin. Oncol. 6, 839-853 (1988).
    • (1988) J. Clin. Oncol. , vol.6 , pp. 839-853
    • Topalian, S.L.1
  • 67
    • 0024510298 scopus 로고
    • Tumour-infiltrating lymphocytes and interleukin-2 in treatment of advanced cancer
    • Kradin, R. L. et al. Tumour-infiltrating lymphocytes and interleukin-2 in treatment of advanced cancer. Lancet 1, 577-580 (1989).
    • (1989) Lancet , vol.1 , pp. 577-580
    • Kradin, R.L.1
  • 68
    • 0026326748 scopus 로고
    • Continuous interleukin-2 and tumor-infiltrating lymphocytes as treatment of advanced melanoma. A national biotherapy study group trial
    • Dillman, R. O. et al. Continuous interleukin-2 and tumor-infiltrating lymphocytes as treatment of advanced melanoma. A national biotherapy study group trial. Cancer 68, 1-8 (1991).
    • (1991) Cancer , vol.68 , pp. 1-8
    • Dillman, R.O.1
  • 69
    • 0027408443 scopus 로고
    • Adoptive immunotherapy of advanced melanoma patients with interleukin-2 (IL-2) and tumor-infiltrating lymphocytes selected in vitro with low doses of IL-2
    • Arienti, F. et al. Adoptive immunotherapy of advanced melanoma patients with interleukin-2 (IL-2) and tumor-infiltrating lymphocytes selected in vitro with low doses of IL-2. Cancer Immunol. Immunother. 36, 315-322 (1993).
    • (1993) Cancer Immunol. Immunother. , vol.36 , pp. 315-322
    • Arienti, F.1
  • 70
    • 0030818791 scopus 로고    scopus 로고
    • Treatment of metastatic renal cell carcinoma with nephrectomy, interleukin-2 and cytokine-primed or CD8(+) selected tumor infiltrating lymphocytes from primary tumor
    • Figlin, R. A. et al. Treatment of metastatic renal cell carcinoma with nephrectomy, interleukin-2 and cytokine-primed or CD8(+) selected tumor infiltrating lymphocytes from primary tumor. J. Urol. 158, 740-745 (1997).
    • (1997) J. Urol. , vol.158 , pp. 740-745
    • Figlin, R.A.1
  • 71
    • 0033506158 scopus 로고    scopus 로고
    • Pilot study of local autologous tumor infiltrating lymphocytes for the treatment of recurrent malignant gliomas
    • Quattrocchi, K. B. et al. Pilot study of local autologous tumor infiltrating lymphocytes for the treatment of recurrent malignant gliomas. J. Neurooncol. 45, 141-157 (1999).
    • (1999) J. Neurooncol. , vol.45 , pp. 141-157
    • Quattrocchi, K.B.1
  • 72
    • 0037085937 scopus 로고    scopus 로고
    • Circulating tumor-reactive CD8(+) T cells in melanoma patients contain a CD45RA(+)CCR7(-) effector subset exerting ex vivo tumor-specific cytolytic activity
    • Valmori, D. et al. Circulating tumor-reactive CD8(+) T cells in melanoma patients contain a CD45RA(+)CCR7(-) effector subset exerting ex vivo tumor-specific cytolytic activity. Cancer Res. 62, 1743-1750 (2002).
    • (2002) Cancer Res. , vol.62 , pp. 1743-1750
    • Valmori, D.1
  • 73
    • 0028117266 scopus 로고
    • Characterization of tumor-infiltrating lymphocyte subsets from human renal cell carcinoma: Specific reactivity defined by cytotoxicity, interferon-gamma secretion, and proliferation
    • Finke, J. H. et al. Characterization of tumor-infiltrating lymphocyte subsets from human renal cell carcinoma: specific reactivity defined by cytotoxicity, interferon-gamma secretion, and proliferation. J. Immunother. Emphasis. Tumor Immunol. 15, 91-104 (1994).
    • (1994) J. Immunother. Emphasis. Tumor Immunol. , vol.15 , pp. 91-104
    • Finke, J.H.1
  • 74
    • 0027234997 scopus 로고
    • Specific immune recognition of autologous tumor by lymphocytes infiltrating colon carcinomas: Analysis by cytokine secretion
    • Hom, S. S., Rosenberg, S. A. & Topalian, S. L. Specific immune recognition of autologous tumor by lymphocytes infiltrating colon carcinomas: analysis by cytokine secretion. Cancer Immunol. Immunother. 36, 1-8 (1993).
    • (1993) Cancer Immunol. Immunother. , vol.36 , pp. 1-8
    • Hom, S.S.1    Rosenberg, S.A.2    Topalian, S.L.3
  • 75
    • 0030887192 scopus 로고    scopus 로고
    • HLA class-I-restricted and tumor-specific CTL in tumor-infiltrating lymphocytes of patients with gastric cancer
    • Hoshino, T. et al. HLA class-I-restricted and tumor-specific CTL in tumor-infiltrating lymphocytes of patients with gastric cancer. Int. J. Cancer 70, 631-638 (1997).
    • (1997) Int. J. Cancer , vol.70 , pp. 631-638
    • Hoshino, T.1
  • 76
    • 0024206263 scopus 로고
    • Different immune functions of peripheral blood, regional lymph node, and tumor infiltrating lymphocytes in lung cancer patients
    • Nakamura, H., Ishiguro, K., & Mon, T. Different immune functions of peripheral blood, regional lymph node, and tumor infiltrating lymphocytes in lung cancer patients. Cancer 62, 2489-2497 (1988).
    • (1988) Cancer , vol.62 , pp. 2489-2497
    • Nakamura, H.1    Ishiguro, K.2    Mon, T.3
  • 77
    • 0026653867 scopus 로고
    • Characterization of lymphocytes infiltrating human breast cancer specific immune reactivity detected by measuring cytokine secretion
    • Schwartzentruber, D. J., Solomon, D., Rosenberg, S. A. & Topalian, S. L. Characterization of lymphocytes infiltrating human breast cancer specific immune reactivity detected by measuring cytokine secretion. J. Immunother. 12, 1-12 (1992).
    • (1992) J. Immunother. , vol.12 , pp. 1-12
    • Schwartzentruber, D.J.1    Solomon, D.2    Rosenberg, S.A.3    Topalian, S.L.4
  • 78
    • 0022446727 scopus 로고
    • Interleukin 2 activation of cytotoxic T-lymphocytes infiltrating into human metastatic melanomas
    • Itoh, K., Tilden, A. B., & Balch, C. M. Interleukin 2 activation of cytotoxic T-lymphocytes infiltrating into human metastatic melanomas. Cancer Res. 46, 3011-3017 (1986).
    • (1986) Cancer Res. , vol.46 , pp. 3011-3017
    • Itoh, K.1    Tilden, A.B.2    Balch, C.M.3
  • 79
    • 0024390061 scopus 로고
    • Tumor-specific cytolysis by lymphocytes infiltrating human melanomas
    • Topalian, S. L., Solomon, D., & Rosenberg, S. A. Tumor-specific cytolysis by lymphocytes infiltrating human melanomas. J. Immunol. 142, 3714-3725 (1989).
    • (1989) J. Immunol. , vol.142 , pp. 3714-3725
    • Topalian, S.L.1    Solomon, D.2    Rosenberg, S.A.3
  • 80
    • 0029882491 scopus 로고    scopus 로고
    • Growth of tumor-infiltrating lymphocytes from human solid cancers: Summary of a 5-year experience
    • Yannelli, J. R. et al. Growth of tumor-infiltrating lymphocytes from human solid cancers: summary of a 5-year experience. Int. J. Cancer 65, 413-421 (1996).
    • (1996) Int. J. Cancer , vol.65 , pp. 413-421
    • Yannelli, J.R.1
  • 81
    • 0037829421 scopus 로고    scopus 로고
    • Generation of tumor-infiltrating lymphocyte cultures for use in adoptive transfer therapy for melanoma patients
    • Dudley, M. E., Wunderlich, J, R., Shelton, T. E., Even, J. & Rosenberg, S. A. Generation of tumor-infiltrating lymphocyte cultures for use in adoptive transfer therapy for melanoma patients. J. Immunother. 26, 332-342 (2003).
    • (2003) J. Immunother. , vol.26 , pp. 332-342
    • Dudley, M.E.1    Wunderlich, J.R.2    Shelton, T.E.3    Even, J.4    Rosenberg, S.A.5
  • 82
    • 0028031582 scopus 로고
    • Treatment of patients with metastatic melanoma with autologous tumor-infiltrating lymphocytes and interleukin 2
    • Rosenberg, S. A. et al. Treatment of patients with metastatic melanoma with autologous tumor-infiltrating lymphocytes and interleukin 2. J. Natl Cancer Inst. 86, 1159-1166 (1994). A comprehensive summary of the clinical experience with TIL for the treatment of patients with melanoma in the absence of non-myeloablative conditioning.
    • (1994) J. Natl Cancer Inst. , vol.86 , pp. 1159-1166
    • Rosenberg, S.A.1
  • 83
    • 0024988334 scopus 로고
    • Gene transfer into humans: Immunotherapy of patients with advanced melanoma, using tumor-infiltrating lymphocytes modified by retroviral gene transduction
    • Rosenberg, S. A. et al. Gene transfer into humans: immunotherapy of patients with advanced melanoma, using tumor-infiltrating lymphocytes modified by retroviral gene transduction. N. Engl. Med. 323, 570-578 (1990).
    • (1990) N. Engl. Med. , vol.323 , pp. 570-578
    • Rosenberg, S.A.1
  • 84
    • 0036073839 scopus 로고    scopus 로고
    • Making room for T cells
    • Maine, G. N. & Mule, J. J. Making room for T cells. J. Clin. Invest. 110, 157-159 (2002).
    • (2002) J. Clin. Invest. , vol.110 , pp. 157-159
    • Maine, G.N.1    Mule, J.J.2
  • 85
    • 0035471754 scopus 로고    scopus 로고
    • Interleukin-7: Master regulator of peripheral T-cell homeostasis?
    • Fry T. J. & Mackall, C. L. Interleukin-7: master regulator of peripheral T-cell homeostasis? Trends. Immunol. 22, 564-571 (2001).
    • (2001) Trends. Immunol. , vol.22 , pp. 564-571
    • Fry, T.J.1    Mackall, C.L.2
  • 86
    • 0035425425 scopus 로고    scopus 로고
    • Factors associated with response to high-dose interleukin-2 in patients with metastatic melanoma
    • Phan, G. Q., Attia, P., Steinberg, S. M., White, D. E. & Rosenberg, S. A. Factors associated with response to high-dose interleukin-2 in patients with metastatic melanoma. J. Clin. Oncol. 19, 3477-3482 (2001).
    • (2001) J. Clin. Oncol. , vol.19 , pp. 3477-3482
    • Phan, G.Q.1    Attia, P.2    Steinberg, S.M.3    White, D.E.4    Rosenberg, S.A.5
  • 87
    • 0034606276 scopus 로고    scopus 로고
    • Melanocyte destruction after antigen-specific immunotherapy of melanoma. Direct evidence of T cell-mediated vitiligo
    • Yee, C. et al. Melanocyte destruction after antigen-specific immunotherapy of melanoma. Direct evidence of T cell-mediated vitiligo. J. Exp. Med. 192, 1637-1644 (2000).
    • (2000) J. Exp. Med. , vol.192 , pp. 1637-1644
    • Yee, C.1
  • 88
    • 0033517152 scopus 로고    scopus 로고
    • Combination immunotherapy of B16 melanoma using anti-cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) and granulocyte/macrophage colony-stimulating factor (GM-CSF)-producing vaccines induces rejection of subcutaneous and metastatic tumors accompanied by autoimmune depigmentation
    • van Elsas, A., Hurwitz, A. A. & Allison, J. P. Combination immunotherapy of B16 melanoma using anti-cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) and granulocyte/macrophage colony-stimulating factor (GM-CSF)-producing vaccines induces rejection of subcutaneous and metastatic tumors accompanied by autoimmune depigmentation. J. Exp. Med. 190, 355-366 (1999).
    • (1999) J. Exp. Med. , vol.190 , pp. 355-366
    • Van Elsas, A.1    Hurwitz, A.A.2    Allison, J.P.3
  • 89
    • 0032980503 scopus 로고    scopus 로고
    • Vaccination with a recombinant vaccinia virus encoding a 'self' antigen induces autoimmune vitiligo and tumor cell destruction in mice: Requirement for CD4(+) T lymphocytes
    • Overwijk, W. W. et al. Vaccination with a recombinant vaccinia virus encoding a 'self' antigen induces autoimmune vitiligo and tumor cell destruction in mice: requirement for CD4(+) T lymphocytes. Proc. Natl Acad. Sci. USA 96, 2982-2987 (1999).
    • (1999) Proc. Natl. Acad. Sci. USA , vol.96 , pp. 2982-2987
    • Overwijk, W.W.1
  • 90
    • 0038153907 scopus 로고    scopus 로고
    • Cancer regression and autoimmunity induced by cytotoxic T lymphocyte-associated antigen 4 blockade in patients with metastatic melanoma
    • Phan, G. Q. et al. Cancer regression and autoimmunity induced by cytotoxic T lymphocyte-associated antigen 4 blockade in patients with metastatic melanoma. Proc. Natl Acad. Sci. USA 100, 8372-8377 (2003).
    • (2003) Proc. Natl. Acad. Sci. USA , vol.100 , pp. 8372-8377
    • Phan, G.Q.1
  • 91
    • 0033168142 scopus 로고    scopus 로고
    • Efficient transfer of a tumor antigen-reactive TCR to human peripheral blood lymphocytes confers antitumor reactivity
    • Clay, T. M. et al. Efficient transfer of a tumor antigen-reactive TCR to human peripheral blood lymphocytes confers antitumor reactivity. J. Immunol. 163, 507-513 (1999).
    • (1999) J. Immunol. , vol.163 , pp. 507-513
    • Clay, T.M.1
  • 92
    • 0029134048 scopus 로고
    • In vivo antitumor activity of T cells redirected with chimeric antibody/T-cell receptor genes
    • Hwu, P. et al. In vivo antitumor activity of T cells redirected with chimeric antibody/T-cell receptor genes. Cancer Res. 55, 3369-3373 (1995).
    • (1995) Cancer Res. , vol.55 , pp. 3369-3373
    • Hwu, P.1
  • 93
    • 0037340417 scopus 로고    scopus 로고
    • Lineage relationship and protective immunity of memory CD 8 T cell subsets
    • Wherry, E. J. et al. Lineage relationship and protective immunity of memory CD8 T cell subsets. Nature Immunol. 4, 225-234 (2003).
    • (2003) Nature Immunol. , vol.4 , pp. 225-234
    • Wherry, E.J.1
  • 94
    • 0038375013 scopus 로고    scopus 로고
    • + memory T-cell subsets in response to antigen or homeostatic cytokines
    • + memory T-cell subsets in response to antigen or homeostatic cytokines. Blood 101, 4260-4266 (2003).
    • (2003) Blood , vol.101 , pp. 4260-4266
    • Geginat, J.1    Lanzavecchia, A.2    Sallusto, F.3
  • 95
    • 0035575701 scopus 로고    scopus 로고
    • Transduction of an IL-2 gene into human melanoma-reactive lymphocytes results in their continued growth in the absence of exogenous IL-2 and maintenance of specific antitumor activity
    • Liu, K. & Rosenberg, S. A. Transduction of an IL-2 gene into human melanoma-reactive lymphocytes results in their continued growth in the absence of exogenous IL-2 and maintenance of specific antitumor activity. J. Immunol. 167, 6356-6365 (2001).
    • (2001) J. Immunol. , vol.167 , pp. 6356-6365
    • Liu, K.1    Rosenberg, S.A.2
  • 96
    • 0037432776 scopus 로고    scopus 로고
    • Defective CD8 T cell memory following acute infection without CD4 T cell help
    • Sun, J. C. & Bevan, M. J. Defective CD8 T cell memory following acute infection without CD4 T cell help. Science 300, 339-342 (2003).
    • (2003) Science , vol.300 , pp. 339-342
    • Sun, J.C.1    Bevan, M.J.2
  • 97
    • 0037432787 scopus 로고    scopus 로고
    • Requirement for CD4 T cell help in generating functional CD8 T cell memory
    • Shedlock, D. J. & Shen, H. Requirement for CD4 T cell help in generating functional CD8 T cell memory. Science 300, 337-339 (2003).
    • (2003) Science , vol.300 , pp. 337-339
    • Shedlock, D.J.1    Shen, H.2


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