How important is protein kinase C in μ-opioid receptor desensitization and morphine tolerance?

Trends in Pharmacological Sciences

Volumn 27, Issue 11, 2006, Pages 558-565

  Bailey, Chris P ^a   Smith, Forrest L ^b   Kelly, Eamonn ^a   Dewey, William L ^b   Henderson, Graeme ^a  

^a UNIVERSITY OF BRISTOL   (United Kingdom)

^b VIRGINIA COMMONWEALTH UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIC AMP DEPENDENT PROTEIN KINASE; G PROTEIN COUPLED RECEPTOR KINASE; MORPHINE; MU OPIATE RECEPTOR; OPIATE AGONIST; PHOSPHOTRANSFERASE INHIBITOR; PROTEIN KINASE C; PROTEIN KINASE C ALPHA; PROTEIN KINASE C BETA; PROTEIN KINASE C DELTA; PROTEIN KINASE C EPSILON; PROTEIN KINASE C ETA; PROTEIN KINASE C GAMMA; PROTEIN KINASE C INHIBITOR; PROTEIN KINASE C THETA; PROTEIN KINASE C ZETA; PROTEIN KINASE C[19-31]; RECOMBINANT RECEPTOR; UNCLASSIFIED DRUG;

ANALGESIC ACTIVITY; ANALGESIC AGENT ABUSE; ARTICLE; BRAIN NERVE CELL; CONFORMATIONAL TRANSITION; HUMAN; HYPERALGESIA; MORPHINE TOLERANCE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; RECEPTOR BINDING; RECEPTOR DOWN REGULATION;

ANALGESICS, OPIOID; ANIMALS; DRUG TOLERANCE; HUMANS; ISOENZYMES; MORPHINE; PHOSPHORYLATION; PROTEIN KINASE C; PROTEIN KINASE INHIBITORS; RECEPTORS, OPIOID, MU;

EID: 33750018978     PISSN: 01656147     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tips.2006.09.006     Document Type: Article

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