Agonist induced homologous desensitization of μ-opioid receptors mediated by G protein-coupled receptor kinases is dependent on agonist efficacy

Molecular Pharmacology

Volumn 54, Issue 4, 1998, Pages 704-711

  Kovoor, Abraham ^a   Celver, Jeremy P ^a   Wu, Albert ^a   Chavkin, Charles ^a  

^a UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BETA ADRENERGIC RECEPTOR; BUPRENORPHINE; ENKEPHALIN[2 DEXTRO ALANINE 4 METHYLPHENYLALANINE 5 GLYCINE]; FENTANYL; GUANINE NUCLEOTIDE BINDING PROTEIN; MORPHINE; MU OPIATE RECEPTOR; NALOXONE; OPIATE AGONIST; PROTEIN KINASE; RECEPTOR PROTEIN; SUFENTANIL;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; DRUG EFFICACY; DRUG RECEPTOR BINDING; DRUG TOLERANCE; NONHUMAN; OOCYTE; PRIORITY JOURNAL; PROTEIN EXPRESSION; RECEPTOR DOWN REGULATION; VOLTAGE CLAMP; XENOPUS LAEVIS;

ANALGESICS, OPIOID; ANIMALS; ENKEPHALIN, ALA(2)-MEPHE(4)-GLY(5)-; ENKEPHALINS; FENTANYL; HUMANS; KINETICS; MORPHINE; POTASSIUM CHANNELS; PROTEIN-SERINE-THREONINE KINASES; RATS; RECEPTOR PROTEIN-TYROSINE KINASES; RECEPTORS, OPIOID, MU; SENSITIVITY AND SPECIFICITY; XENOPUS LAEVIS;

EID: 0031726194     PISSN: 0026895X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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