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Volumn 66, Issue 5, 2004, Pages 1285-1292

Role of mPKCI, a novel μ-opioid receptor interactive protein, in receptor desensitization, phosphorylation, and morphine-induced analgesia

Author keywords

[No Author keywords available]

Indexed keywords

DELTA OPIATE RECEPTOR; MORPHINE; MU OPIATE RECEPTOR; PROTEIN; PROTEIN KINASE C INTERACTING PROTEIN; UNCLASSIFIED DRUG;

EID: 6944233607     PISSN: 0026895X     EISSN: None     Source Type: Journal    
DOI: 10.1124/mol.66.5.     Document Type: Article
Times cited : (79)

References (40)
  • 1
    • 0034623933 scopus 로고    scopus 로고
    • Tyrosine phosphorylation of the kappa -opioid receptor regulates agonist efficacy
    • Appleyard SM, McLaughlin JP, and Chavkin C (2000) Tyrosine phosphorylation of the kappa -opioid receptor regulates agonist efficacy. J Biol Chem 275:38281-38285.
    • (2000) J Biol Chem , vol.275 , pp. 38281-38285
    • Appleyard, S.M.1    McLaughlin, J.P.2    Chavkin, C.3
  • 2
    • 0030662153 scopus 로고    scopus 로고
    • Agonist-induced phosphorylation of the kappa-opioid receptor
    • Appleyard SM, Patterson TA, Jin W, and Chavkin C (1997) Agonist-induced phosphorylation of the kappa-opioid receptor. J Neurochem 69:2405-2412.
    • (1997) J Neurochem , vol.69 , pp. 2405-2412
    • Appleyard, S.M.1    Patterson, T.A.2    Jin, W.3    Chavkin, C.4
  • 3
    • 0029130047 scopus 로고
    • Phosphorylation and agonist specific intracellular trafficking of an epitope-tagged mu-opioid receptor expressed in HEK 293 cells
    • Arden JH, Segredo V, Wang Z, Lameh J, and Sadee W (1995) Phosphorylation and agonist specific intracellular trafficking of an epitope-tagged mu-opioid receptor expressed in HEK 293 cells. J Neurochem 65:1636-1645.
    • (1995) J Neurochem , vol.65 , pp. 1636-1645
    • Arden, J.H.1    Segredo, V.2    Wang, Z.3    Lameh, J.4    Sadee, W.5
  • 5
    • 0034619796 scopus 로고    scopus 로고
    • Mu-opioid receptor desensitization by beta-arrestin-2 determines morphine tolerance but not dependence
    • Bohn LM, Gainetdinov RR, Lin FT, Lefkowitz RJ, and Caron MG (2000) Mu-opioid receptor desensitization by beta-arrestin-2 determines morphine tolerance but not dependence. Nature (Lond) 408:720-723.
    • (2000) Nature (Lond) , vol.408 , pp. 720-723
    • Bohn, L.M.1    Gainetdinov, R.R.2    Lin, F.T.3    Lefkowitz, R.J.4    Caron, M.G.5
  • 7
    • 0000739936 scopus 로고    scopus 로고
    • Selected cysteine residues in transmembrane domains of μ-opioid receptor are critical for effects of sulfhydryl reagents
    • Deng HB, Guang W, and Wang JB (2000) Selected cysteine residues in transmembrane domains of μ-opioid receptor are critical for effects of sulfhydryl reagents. J Pharmacol Exp Ther 293:113-120.
    • (2000) J Pharmacol Exp Ther , vol.293 , pp. 113-120
    • Deng, H.B.1    Guang, W.2    Wang, J.B.3
  • 8
    • 0025812324 scopus 로고
    • Model systems for the study of seven-transmembrane-segment receptors
    • Dohlman HG, Thorner J, Caron MG, and Lefkowitz RJ (1991) Model systems for the study of seven-transmembrane-segment receptors. Annu Rev Biochem 60:653-688.
    • (1991) Annu Rev Biochem , vol.60 , pp. 653-688
    • Dohlman, H.G.1    Thorner, J.2    Caron, M.G.3    Lefkowitz, R.J.4
  • 9
    • 0028916344 scopus 로고
    • Four consecutive serines in the third intracellular loop are the sites for β-adrenergic receptor kinase-mediated phosphorylation and desensitization of the α2A-adrenergic receptor
    • Eason MG, Moreira SP, and Liggett SB (1995) Four consecutive serines in the third intracellular loop are the sites for β-adrenergic receptor kinase-mediated phosphorylation and desensitization of the α2A-adrenergic receptor. J Biol Chem 270:4681-4688.
    • (1995) J Biol Chem , vol.270 , pp. 4681-4688
    • Eason, M.G.1    Moreira, S.P.2    Liggett, S.B.3
  • 10
    • 0029854366 scopus 로고    scopus 로고
    • G-protein-coupled receptor kinases and arrestins: Regulators of G-protein-coupled receptor sequestration
    • Ferguson SS, Zhang J, Barak LS, and Caron MG (1996) G-protein-coupled receptor kinases and arrestins: regulators of G-protein-coupled receptor sequestration. Biochem Soc Trans 24:953-959.
    • (1996) Biochem Soc Trans , vol.24 , pp. 953-959
    • Ferguson, S.S.1    Zhang, J.2    Barak, L.S.3    Caron, M.G.4
  • 11
    • 0035819078 scopus 로고    scopus 로고
    • Endocytosis of the μ-opioid receptor reduces tolerance and a cellular hallmark of opiate withdrawal
    • Finn AK and Whistler JL (2001) Endocytosis of the μ-opioid receptor reduces tolerance and a cellular hallmark of opiate withdrawal. Neuron 32:829-839.
    • (2001) Neuron , vol.32 , pp. 829-839
    • Finn, A.K.1    Whistler, J.L.2
  • 12
    • 0025996363 scopus 로고
    • The major endogenous bovine brain protein kinase C inhibitor is a heat-labile protein
    • Fraser ED and Walsh MP (1991) The major endogenous bovine brain protein kinase C inhibitor is a heat-labile protein. FEBS Lett 294:285-289.
    • (1991) FEBS Lett , vol.294 , pp. 285-289
    • Fraser, E.D.1    Walsh, M.P.2
  • 13
    • 0037169345 scopus 로고    scopus 로고
    • Regulation of opioid receptor trafficking and morphine tolerance by receptor oligomerization
    • He L, Fong J, von Zastrow M, and Whistler JL (2002) Regulation of opioid receptor trafficking and morphine tolerance by receptor oligomerization. Cell 108:271-282.
    • (2002) Cell , vol.108 , pp. 271-282
    • He, L.1    Fong, J.2    Von Zastrow, M.3    Whistler, J.L.4
  • 14
    • 0034011235 scopus 로고    scopus 로고
    • Protein kinase C-mediated acute tolerance to peripheral μ-opioid analgesia in the bradykinin-nociception test in mice
    • Inoue M and Ueda H (2000) Protein kinase C-mediated acute tolerance to peripheral μ-opioid analgesia in the bradykinin-nociception test in mice. J Pharmacol Exp Ther 283:662-669.
    • (2000) J Pharmacol Exp Ther , vol.283 , pp. 662-669
    • Inoue, M.1    Ueda, H.2
  • 16
    • 0036095186 scopus 로고    scopus 로고
    • Exploring the opioid system by gene knock-out
    • Kieffer BL and Gaveriaux-Ruff C (2002) Exploring the opioid system by gene knock-out. Prog Neurobiol 66:285-306.
    • (2002) Prog Neurobiol , vol.66 , pp. 285-306
    • Kieffer, B.L.1    Gaveriaux-Ruff, C.2
  • 17
    • 0032505718 scopus 로고    scopus 로고
    • Characterization of PKCI and comparative studies with FHIT, related members of the HIT protein family
    • Klein MG, Yao Y, Slosberg ED, Lima CD, Doki Y, and Weinstein IB (1998) Characterization of PKCI and comparative studies with FHIT, related members of the HIT protein family. Exp Cell Res 244:26-32.
    • (1998) Exp Cell Res , vol.244 , pp. 26-32
    • Klein, M.G.1    Yao, Y.2    Slosberg, E.D.3    Lima, C.D.4    Doki, Y.5    Weinstein, I.B.6
  • 18
    • 0032577554 scopus 로고    scopus 로고
    • Carboxyl-terminal splicing of the rat μ-opioid receptor modulates agonist-mediated internalization and receptor resensitization
    • Koch T, Schulz S, Schroder H, Wolf R, Raulf E, and Hollt V (1998) Carboxyl-terminal splicing of the rat μ-opioid receptor modulates agonist-mediated internalization and receptor resensitization. J Biol Chem 273:13652-13657.
    • (1998) J Biol Chem , vol.273 , pp. 13652-13657
    • Koch, T.1    Schulz, S.2    Schroder, H.3    Wolf, R.4    Raulf, E.5    Hollt, V.6
  • 19
    • 0034666697 scopus 로고    scopus 로고
    • Tyrosine phosphorylation of the delta-opioid receptor. Evidence for its role in mitogen-activated protein kinase activation and receptor internalization
    • Kramer HK, Andria ML, Esposito DH, and Simon EJ (2000) Tyrosine phosphorylation of the delta-opioid receptor. Evidence for its role in mitogen-activated protein kinase activation and receptor internalization. Biochem Pharmacol 60:781-792.
    • (2000) Biochem Pharmacol , vol.60 , pp. 781-792
    • Kramer, H.K.1    Andria, M.L.2    Esposito, D.H.3    Simon, E.J.4
  • 20
    • 0031747997 scopus 로고    scopus 로고
    • The role of receptor kinases and arrestins in G protein-coupled receptor regulation
    • Krupnick JG and Benovic JL (1998) The role of receptor kinases and arrestins in G protein-coupled receptor regulation. Annu Rev Pharmacol Toxicol 38:289-319.
    • (1998) Annu Rev Pharmacol Toxicol , vol.38 , pp. 289-319
    • Krupnick, J.G.1    Benovic, J.L.2
  • 21
    • 0021272516 scopus 로고
    • Down-regulation of opiate receptor in neuroblastoma x glioma NG108-15 hybrid cells. Chloroquine promotes accumulation of tritiated enkephalin in the lysosomes
    • Law PY, Hom DS, and Loh HH (1984) Down-regulation of opiate receptor in neuroblastoma x glioma NG108-15 hybrid cells. Chloroquine promotes accumulation of tritiated enkephalin in the lysosomes. J Biol Chem 259:4096-4104.
    • (1984) J Biol Chem , vol.259 , pp. 4096-4104
    • Law, P.Y.1    Hom, D.S.2    Loh, H.H.3
  • 23
    • 0032563291 scopus 로고    scopus 로고
    • G protein-coupled receptors. III. New roles for receptor kinases and β-arrestins in receptor signaling and desensitization
    • Lefkowitz RJ (1998) G protein-coupled receptors. III. New roles for receptor kinases and β-arrestins in receptor signaling and desensitization. J Biol Chem 273:18677-18680.
    • (1998) J Biol Chem , vol.273 , pp. 18677-18680
    • Lefkowitz, R.J.1
  • 24
    • 0037178820 scopus 로고    scopus 로고
    • + exchanger regulatory factor (EBP50/NHERF) blocks U50,488H-induced down-regulation of the human κ opioid receptor by enhancing its recycling rate
    • + exchanger regulatory factor (EBP50/NHERF) blocks U50,488H-induced down-regulation of the human κ opioid receptor by enhancing its recycling rate. J Biol Chem 277:27545-27552.
    • (2002) J Biol Chem , vol.277 , pp. 27545-27552
    • Li, J.G.1    Chen, C.2    Liu-Chen, L.Y.3
  • 25
    • 0030831990 scopus 로고    scopus 로고
    • Structure-based analysis of catalysis and substrate definition in the HIT protein family
    • Lima CD, Klein MG, and Hendrickson WA (1997) Structure-based analysis of catalysis and substrate definition in the HIT protein family. Science (Wash DC) 278:286-290.
    • (1997) Science (Wash DC) , vol.278 , pp. 286-290
    • Lima, C.D.1    Klein, M.G.2    Hendrickson, W.A.3
  • 26
    • 0029085874 scopus 로고
    • Agonist-dependent phosphorylation of the mouse 32 δ-opioid receptor: Involvement of G protein-coupled receptor kinases but not protein kinase C
    • Pei G, Kieffer BL, Lefkowitz RJ, and Freedman NJ (1995) Agonist-dependent phosphorylation of the mouse 32 δ-opioid receptor: involvement of G protein-coupled receptor kinases but not protein kinase C. Mol Pharmacol 48:173-177.
    • (1995) Mol Pharmacol , vol.48 , pp. 173-177
    • Pei, G.1    Kieffer, B.L.2    Lefkowitz, R.J.3    Freedman, N.J.4
  • 27
    • 0032524665 scopus 로고    scopus 로고
    • A mitogen-activated protein kinase pathway is required for μ-opioid receptor desensitization
    • Polakiewicz RD, Schieferl SM, Dorner LF, Kansra V, and Comb MJ (1998) A mitogen-activated protein kinase pathway is required for μ-opioid receptor desensitization. J Biol Chem 273:12402-12406.
    • (1998) J Biol Chem , vol.273 , pp. 12402-12406
    • Polakiewicz, R.D.1    Schieferl, S.M.2    Dorner, L.F.3    Kansra, V.4    Comb, M.J.5
  • 28
    • 0031030042 scopus 로고    scopus 로고
    • Opiate receptor knockout mice define mu receptor roles in endogenous nociceptive responses and morphine-induced analgesia
    • Sora I, Takahashi N, Funada M, Ujike H, Revay RS, Donovan DM, Miner LL, and Uhl GR (1997) Opiate receptor knockout mice define mu receptor roles in endogenous nociceptive responses and morphine-induced analgesia. Proc Natl Acad Sci USA 100:7824-7829.
    • (1997) Proc Natl Acad Sci USA , vol.100 , pp. 7824-7829
    • Sora, I.1    Takahashi, N.2    Funada, M.3    Ujike, H.4    Revay, R.S.5    Donovan, D.M.6    Miner, L.L.7    Uhl, G.R.8
  • 30
    • 0037934419 scopus 로고    scopus 로고
    • Deletion of histidine triad nucleotide-binding protein 1/PKC-interacting protein in mice enhances cell growth and carcinogenesis
    • Su T, Suzui M, Wang L, Lin CS, Xin WQ, and Weinstein IB (2003) Deletion of histidine triad nucleotide-binding protein 1/PKC-interacting protein in mice enhances cell growth and carcinogenesis. Proc Natl Acad Sci USA 100:7824-7829.
    • (2003) Proc Natl Acad Sci USA , vol.100 , pp. 7824-7829
    • Su, T.1    Suzui, M.2    Wang, L.3    Lin, C.S.4    Xin, W.Q.5    Weinstein, I.B.6
  • 31
    • 0029825797 scopus 로고    scopus 로고
    • Sequestration of the δ opioid receptor. Role of the C terminus in agonist-mediated internalization
    • Trapaidze N, Keith DE, Cvejic S, Evans CJ, and Devi LA (1996) Sequestration of the δ opioid receptor. Role of the C terminus in agonist-mediated internalization. J Biol Chem 271:29279-29285.
    • (1996) J Biol Chem , vol.271 , pp. 29279-29285
    • Trapaidze, N.1    Keith, D.E.2    Cvejic, S.3    Evans, C.J.4    Devi, L.A.5
  • 32
    • 6944240796 scopus 로고
    • A comparison between Walsh and Fourier analysis of the electroencephalogram for tracking the effects of anesthesia
    • Walsh MP and Dzwonczyk R (1985) A comparison between Walsh and Fourier analysis of the electroencephalogram for tracking the effects of anesthesia. Biochem Biophys Res Commun 129:603-610.
    • (1985) Biochem Biophys Res Commun , vol.129 , pp. 603-610
    • Walsh, M.P.1    Dzwonczyk, R.2
  • 34
    • 0034681348 scopus 로고    scopus 로고
    • Tolerance to morphine at the mu-opioid receptor differentially induced by cAMP-dependent protein kinase activation and morphine
    • Wang Z and Sadee W (2000) Tolerance to morphine at the mu-opioid receptor differentially induced by cAMP-dependent protein kinase activation and morphine. Eur J Pharmacol 389:165-171.
    • (2000) Eur J Pharmacol , vol.389 , pp. 165-171
    • Wang, Z.1    Sadee, W.2
  • 35
    • 0035823533 scopus 로고    scopus 로고
    • A phosphorylation-regulated brake mechanism controls the initial endocytosis of opioid receptors but is not required for post-endocytic sorting to lysosomes
    • Whistler JL, Tsao P, and von Zastrow M (2001) A phosphorylation-regulated brake mechanism controls the initial endocytosis of opioid receptors but is not required for post-endocytic sorting to lysosomes. J Biol Chem 276:34331-34338.
    • (2001) J Biol Chem , vol.276 , pp. 34331-34338
    • Whistler, J.L.1    Tsao, P.2    Von Zastrow, M.3
  • 36
    • 0019947923 scopus 로고
    • Enkephalin opens potassium channels on mammalian central neurones
    • Williams JT, Egan TM, and North RA (1982) Enkephalin opens potassium channels on mammalian central neurones. Nature (Lond) 299:74-77.
    • (1982) Nature (Lond) , vol.299 , pp. 74-77
    • Williams, J.T.1    Egan, T.M.2    North, R.A.3
  • 37
    • 0030691760 scopus 로고    scopus 로고
    • Opioid receptor phosphorylation, desensitization and ligand efficacy
    • Yu Y, Zhang L, Yin X, Sun H, Uhl GR, and Wang JB (1997) μ Opioid receptor phosphorylation, desensitization and ligand efficacy. J Biol Chem 272:28869-28874.
    • (1997) J Biol Chem , vol.272 , pp. 28869-28874
    • Yu, Y.1    Zhang, L.2    Yin, X.3    Sun, H.4    Uhl, G.R.5    Wang, J.B.6
  • 38
    • 0035214481 scopus 로고    scopus 로고
    • Reduced development of tolerance to the analgesic effects of morphine and clonidine in PKC gamma mutant mice
    • Zeitz KP, Malmberg AB, Gilbert H, and Basbaum AI (2001) Reduced development of tolerance to the analgesic effects of morphine and clonidine in PKC gamma mutant mice. Pain 94:245-253.
    • (2001) Pain , vol.94 , pp. 245-253
    • Zeitz, K.P.1    Malmberg, A.B.2    Gilbert, H.3    Basbaum, A.I.4
  • 40
    • 15844416295 scopus 로고    scopus 로고
    • Differential μ opiate receptor phosphorylation and desensitization induced by agonists and phorbol esters
    • Zhang L, Yu Y, Mackin S, Weight FF, Uhl GR, and Wang JB (1996) Differential μ opiate receptor phosphorylation and desensitization induced by agonists and phorbol esters. J Biol Chem 271:11449-11454.
    • (1996) J Biol Chem , vol.271 , pp. 11449-11454
    • Zhang, L.1    Yu, Y.2    Mackin, S.3    Weight, F.F.4    Uhl, G.R.5    Wang, J.B.6


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