Comparison of morphine-6-glucuronide and morphine on respiratory depressant and antinociceptive responses in wild type and μ-opioid receptor deficient mice

British Journal of Anaesthesia

Volumn 91, Issue 6, 2003, Pages 862-870

  Romberg, R ^a   Sarton, E ^a   Teppema, L ^a   Matthes, H W D ^b   Kieffer, B L ^b   Dahan, A ^a  

^a LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

^b INSTITUT DE GÉNÉTIQUE ET DE BIOLOGIE MOLÉCULAIRE ET CELLULAIRE   (France)

Author keywords

Analgesics opioid; Measurement techniques, plethysmography; Model, knockout mouse; Ventilation; Ventilation, control of breathing

Indexed keywords

CARBON DIOXIDE; MORPHINE; MORPHINE 6 GLUCURONIDE; MU OPIATE RECEPTOR;

ANALYSIS OF VARIANCE; ANIMAL EXPERIMENT; ANTINOCICEPTION; ARTICLE; BODY PLETHYSMOGRAPHY; CARBON DIOXIDE BREATHING; CONTROLLED STUDY; DRUG POTENCY; GENOTYPE; LUNG MINUTE VOLUME; MOUSE; NONHUMAN; PRIORITY JOURNAL; RESPIRATION DEPRESSION; STATISTICAL ANALYSIS; STATISTICAL SIGNIFICANCE; TIDAL VOLUME;

EID: 0344237326     PISSN: 00070912     EISSN: None     Source Type: Journal    
DOI: 10.1093/bja/aeg279     Document Type: Article

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