메뉴 건너뛰기




Volumn 177, Issue 7, 2006, Pages 4841-4852

Collaborative action of NF-κB and p38 MAPK is involved in CpG DNA-induced IFN-α and chemokine production in human plasmacytoid dendritic cells

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA INTERFERON; CHEMOKINE; CHLOROQUINE; CPG OLIGODEOXYNUCLEOTIDE; GAMMA INTERFERON; GAMMA INTERFERON INDUCIBLE PROTEIN 10; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERFERON REGULATORY FACTOR 7; MACROPHAGE INFLAMMATORY PROTEIN 1ALPHA; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE INHIBITOR; MITOGEN ACTIVATED PROTEIN KINASE P38; PALINDROMIC DNA; TOLL LIKE RECEPTOR 9;

EID: 33749151638     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.177.7.4841     Document Type: Article
Times cited : (69)

References (59)
  • 1
    • 5444262511 scopus 로고    scopus 로고
    • Toll-like receptor control of the adaptive immune responses
    • Iwasaki, A., and R. Medzhitov. 2004. Toll-like receptor control of the adaptive immune responses. Nat. Immunol. 5: 987-995.
    • (2004) Nat. Immunol. , vol.5 , pp. 987-995
    • Iwasaki, A.1    Medzhitov, R.2
  • 2
    • 15244349785 scopus 로고    scopus 로고
    • Plasmacytoid dendritic cells in immunity
    • Colonna, M., G. Trinchieri, and Y. J. Liu. 2004. Plasmacytoid dendritic cells in immunity. Nat. Immunol. 5: 1219-1226.
    • (2004) Nat. Immunol. , vol.5 , pp. 1219-1226
    • Colonna, M.1    Trinchieri, G.2    Liu, Y.J.3
  • 4
    • 0035903288 scopus 로고    scopus 로고
    • Subsets of human dendritic cell precursors express different Toll-like receptors and respond to different microbial antigens
    • Kadowaki, N., S. Ho, S. Antonenko, R. W. Malefty, R. A. Kastelein, F. Bazan, and Y.-J. Liu. 2001. Subsets of human dendritic cell precursors express different Toll-like receptors and respond to different microbial antigens. J. Exp. Med. 194: 863-869.
    • (2001) J. Exp. Med. , vol.194 , pp. 863-869
    • Kadowaki, N.1    Ho, S.2    Antonenko, S.3    Malefty, R.W.4    Kastelein, R.A.5    Bazan, F.6    Liu, Y.-J.7
  • 7
    • 0036884464 scopus 로고    scopus 로고
    • IFN-producing cells respond to CXCR3 ligands in the presence of CXCL12 and secrete inflammatory chemokines upon activation
    • Krug, A., R. Uppaluri, F. Facchetti, B. G. Dorner, K. C. Sheehan, R. D. Schreiber, M. Cella, and M. Colonna. 2002. IFN-producing cells respond to CXCR3 ligands in the presence of CXCL12 and secrete inflammatory chemokines upon activation. J. Immunol. 169: 6079-6083.
    • (2002) J. Immunol. , vol.169 , pp. 6079-6083
    • Krug, A.1    Uppaluri, R.2    Facchetti, F.3    Dorner, B.G.4    Sheehan, K.C.5    Schreiber, R.D.6    Cella, M.7    Colonna, M.8
  • 8
    • 0037114141 scopus 로고    scopus 로고
    • Differential chemokine production by myeloid and plasmacytoid dendritic cells
    • Penna, G., M. Vulcano, A. Roncari, F. Facchetti, S. Sozzani, and L. Adorini. 2002. Differential chemokine production by myeloid and plasmacytoid dendritic cells. J. Immunol. 169: 6673-6676.
    • (2002) J. Immunol. , vol.169 , pp. 6673-6676
    • Penna, G.1    Vulcano, M.2    Roncari, A.3    Facchetti, F.4    Sozzani, S.5    Adorini, L.6
  • 9
    • 1542313911 scopus 로고    scopus 로고
    • Virally stimulated plasmacytoid dendritic cells produce chemokines and induce migration of T and NK cells
    • Megjugorac, N. J., H. A. Young, S. B. Amrute, S. L. Olshalsky, and P. Fitzgerald-Bocarsly. 2004. Virally stimulated plasmacytoid dendritic cells produce chemokines and induce migration of T and NK cells. J. Leukocyte Biol. 75: 504-514.
    • (2004) J. Leukocyte Biol. , vol.75 , pp. 504-514
    • Megjugorac, N.J.1    Young, H.A.2    Amrute, S.B.3    Olshalsky, S.L.4    Fitzgerald-Bocarsly, P.5
  • 10
    • 9644268181 scopus 로고    scopus 로고
    • The role of type 1 interferons in non-viral infections
    • Bogdan, C., J. Mattner, and U. Schleicher. 2004. The role of type 1 interferons in non-viral infections. Immunol. Rev. 202: 33-48.
    • (2004) Immunol. Rev. , vol.202 , pp. 33-48
    • Bogdan, C.1    Mattner, J.2    Schleicher, U.3
  • 11
    • 0037290878 scopus 로고    scopus 로고
    • Ringing the interferon alarm: Differential regulation of gene expression at the interface between innate and adaptive immunity
    • Levy, D. E., M. Isabelle, and A. Prakash. 2003. Ringing the interferon alarm: differential regulation of gene expression at the interface between innate and adaptive immunity. Curr. Opin. Immunol. 15: 52-58.
    • (2003) Curr. Opin. Immunol. , vol.15 , pp. 52-58
    • Levy, D.E.1    Isabelle, M.2    Prakash, A.3
  • 12
    • 0036467492 scopus 로고    scopus 로고
    • The interferon-αβ system in antiviral responses: A multimodal machinery of gene regulation by the IRF family of transcription factors
    • Taniguchi, T., and A. Takaoka. 2002. The interferon-αβ system in antiviral responses: a multimodal machinery of gene regulation by the IRF family of transcription factors. Curr. Opin. Immunol. 14: 111-116.
    • (2002) Curr. Opin. Immunol. , vol.14 , pp. 111-116
    • Taniguchi, T.1    Takaoka, A.2
  • 13
    • 0034644718 scopus 로고    scopus 로고
    • Regulation of the promoter activity of interferon regulatory factor-7 gene: Activation by interferon and silencing by hypermethylation
    • Lu, R., W. Au, W. Yeow, N. Hagman, and P. M. Pitha. 2000. Regulation of the promoter activity of interferon regulatory factor-7 gene: activation by interferon and silencing by hypermethylation. J. Biol. Chem. 275: 31805-31812.
    • (2000) J. Biol. Chem. , vol.275 , pp. 31805-31812
    • Lu, R.1    Au, W.2    Yeow, W.3    Hagman, N.4    Pitha, P.M.5
  • 15
    • 0037407691 scopus 로고    scopus 로고
    • Activation with CpG-A and CpG-B oligonucleotides reveals two distinct regulatory pathways of type I IFN synthesis in human plasmacytoid dendritic cells
    • Kerkmann, M., S. Rothenfusser, V. Hornung, A. Towarowski, M. Wagner, A. Sarris, T. Giese, S. Endres, and G. Hartmann. 2003. Activation with CpG-A and CpG-B oligonucleotides reveals two distinct regulatory pathways of type I IFN synthesis in human plasmacytoid dendritic cells. J. Immunol. 170: 4465-4474.
    • (2003) J. Immunol. , vol.170 , pp. 4465-4474
    • Kerkmann, M.1    Rothenfusser, S.2    Hornung, V.3    Towarowski, A.4    Wagner, M.5    Sarris, A.6    Giese, T.7    Endres, S.8    Hartmann, G.9
  • 17
    • 1642370060 scopus 로고    scopus 로고
    • Viral infection and Toll-like receptor agonists induce a differential expression of type I and λ interferons in human plasmacytoid and monocyte-derived dendritic cells
    • Coccia, E. M., M. Severa, E. Giacomini, D. Monneron, M. E. Remoli, I. Julkunen, M. Cella, R. Lande, and G. Uze. 2004. Viral infection and Toll-like receptor agonists induce a differential expression of type I and λ interferons in human plasmacytoid and monocyte-derived dendritic cells. Eur. J. Immunol. 34: 796-805.
    • (2004) Eur. J. Immunol. , vol.34 , pp. 796-805
    • Coccia, E.M.1    Severa, M.2    Giacomini, E.3    Monneron, D.4    Remoli, M.E.5    Julkunen, I.6    Cella, M.7    Lande, R.8    Uze, G.9
  • 20
    • 3142724031 scopus 로고    scopus 로고
    • Toll-like receptor signaling
    • Akira, A., and K. Takeda. 2004. Toll-like receptor signaling. Nat. Rev. Immunol. 4: 499-511.
    • (2004) Nat. Rev. Immunol. , vol.4 , pp. 499-511
    • Akira, A.1    Takeda, K.2
  • 21
    • 0037053327 scopus 로고    scopus 로고
    • Stimulation of IRF-7 gene expression by tumor necrosis factor a: Requirement for NF-κB transcription factor and gene accessibility
    • Lu, R., P. A. Moore, and P. M. Pitha. 2002. Stimulation of IRF-7 gene expression by tumor necrosis factor a: requirement for NF-κB transcription factor and gene accessibility. J. Biol. Chem. 277: 16592-16598.
    • (2002) J. Biol. Chem. , vol.277 , pp. 16592-16598
    • Lu, R.1    Moore, P.A.2    Pitha, P.M.3
  • 22
    • 0035202289 scopus 로고    scopus 로고
    • Intracellular signaling molecules activated by Epstein-Barr virus for induction of interferon regulatory factor 7
    • Zhang, L., L. Wu, K. Hong, and J. S. Pagano. 2001. Intracellular signaling molecules activated by Epstein-Barr virus for induction of interferon regulatory factor 7. J. Virol. 75: 12393-12401.
    • (2001) J. Virol. , vol.75 , pp. 12393-12401
    • Zhang, L.1    Wu, L.2    Hong, K.3    Pagano, J.S.4
  • 23
    • 0026625208 scopus 로고
    • Unique palindromic sequences in synthetic oligonucleotides are required to induce IFN and augment IFN-mediated natural killer activity
    • Yamamoto, S., T. Yamamoto, T. Kataoka, E. Kuramoto, O. Yano, and T. Tokunaga. 1992. Unique palindromic sequences in synthetic oligonucleotides are required to induce IFN and augment IFN-mediated natural killer activity. J. Immunol. 148: 4072-4076.
    • (1992) J. Immunol. , vol.148 , pp. 4072-4076
    • Yamamoto, S.1    Yamamoto, T.2    Kataoka, T.3    Kuramoto, E.4    Yano, O.5    Tokunaga, T.6
  • 24
    • 0032829670 scopus 로고    scopus 로고
    • How BCG led to the discovery of immunostimulatory DNA
    • Tokunaga, T., T. Yamamoto, and S. Yamamoto. 1999. How BCG led to the discovery of immunostimulatory DNA. Jpn. J. Infect. Dis. 52: 1-11.
    • (1999) Jpn. J. Infect. Dis. , vol.52 , pp. 1-11
    • Tokunaga, T.1    Yamamoto, T.2    Yamamoto, S.3
  • 25
    • 0034633822 scopus 로고    scopus 로고
    • Influenza A and Sendai viruses induce differential chemokine gene expression and transcription factor activation in human macrophages
    • Matikainen, S., J. Pirhonen, M. Miettinen, A. Lehtonen, C. Govenius-Vintola, T. Sareneva, and I. Julkunen. 2000. Influenza A and Sendai viruses induce differential chemokine gene expression and transcription factor activation in human macrophages. Virology 276: 138-147.
    • (2000) Virology , vol.276 , pp. 138-147
    • Matikainen, S.1    Pirhonen, J.2    Miettinen, M.3    Lehtonen, A.4    Govenius-Vintola, C.5    Sareneva, T.6    Julkunen, I.7
  • 26
    • 0031938384 scopus 로고    scopus 로고
    • Induction of macrophage-inflammatory protein 1α (MIP-1α) by inteferon-α
    • Bug, G., M. J. Aman, T. Tretter, C. Huber, and C. Peschel. 1998. Induction of macrophage-inflammatory protein 1α (MIP-1α) by inteferon-α. Exp. Hematol. 26: 117-123.
    • (1998) Exp. Hematol. , vol.26 , pp. 117-123
    • Bug, G.1    Aman, M.J.2    Tretter, T.3    Huber, C.4    Peschel, C.5
  • 27
    • 0036234459 scopus 로고    scopus 로고
    • Missing pieces in the NF-κB puzzle
    • Ghosh, S., and M. Karin. 2002. Missing pieces in the NF-κB puzzle. Cell 109: S81-S96.
    • (2002) Cell , vol.109
    • Ghosh, S.1    Karin, M.2
  • 29
    • 0032476602 scopus 로고    scopus 로고
    • CpG-DNA-specific activation of antigen-presenting cells requires stress kinase activity and is preceded by non-specific endocytosis and endosomal maturation
    • Häcker, H., H. Mischak, T. Miethke, S. Liptay, R. Schmid, T. Sparwasser, K. Heeg, G. B. Lipford, and H. Wagner. 1998. CpG-DNA-specific activation of antigen-presenting cells requires stress kinase activity and is preceded by non-specific endocytosis and endosomal maturation. EMBO J. 17: 6230-6240.
    • (1998) EMBO J. , vol.17 , pp. 6230-6240
    • Häcker, H.1    Mischak, H.2    Miethke, T.3    Liptay, S.4    Schmid, R.5    Sparwasser, T.6    Heeg, K.7    Lipford, G.B.8    Wagner, H.9
  • 30
    • 0036219195 scopus 로고    scopus 로고
    • CpG motifs in bacterial DNA and their immune effects
    • Krieg, A. M. 2002. CpG motifs in bacterial DNA and their immune effects. Annu. Rev. Immunol. 20: 709-760.
    • (2002) Annu. Rev. Immunol. , vol.20 , pp. 709-760
    • Krieg, A.M.1
  • 31
    • 3242759674 scopus 로고    scopus 로고
    • Regulation of IFN regulatory factor-7 and IFN-α production by enveloped virus and lipopolysaccharide in human plasmacytoid dendritic cells
    • Dai, J., N. J. Megjuborac, S. B. Amrute, and P. Fitzgerald-Bocarsly. 2004. Regulation of IFN regulatory factor-7 and IFN-α production by enveloped virus and lipopolysaccharide in human plasmacytoid dendritic cells. J. Immunol. 173: 1535-1548.
    • (2004) J. Immunol. , vol.173 , pp. 1535-1548
    • Dai, J.1    Megjuborac, N.J.2    Amrute, S.B.3    Fitzgerald-Bocarsly, P.4
  • 33
    • 0037099629 scopus 로고    scopus 로고
    • Potential role of phosphatidylinositol 3 kinase, rather than DNA-dependent protein kinase, in CpG DNA-induced immune activation
    • Ishii, K. J., F. Takeshita, I. Gursel, M. Gursel, J. Conover, A. Nussenzweig, and D. M. Klinman. 2002. Potential role of phosphatidylinositol 3 kinase, rather than DNA-dependent protein kinase, in CpG DNA-induced immune activation. J. Exp. Med. 196: 269-274.
    • (2002) J. Exp. Med. , vol.196 , pp. 269-274
    • Ishii, K.J.1    Takeshita, F.2    Gursel, I.3    Gursel, M.4    Conover, J.5    Nussenzweig, A.6    Klinman, D.M.7
  • 34
    • 0034292405 scopus 로고    scopus 로고
    • Effects of a hexameric deoxyriboguanosine run conjugation into CpG oligodeoxynucleotides on their immunostimulation potentials
    • Lee, S. W., M. K. Song, K. H. Back, Y. Park, J. K. Kim, C. H. Lee, H. K. Cheong, C. Cheong, and Y. C. Sung. 2000. Effects of a hexameric deoxyriboguanosine run conjugation into CpG oligodeoxynucleotides on their immunostimulation potentials. J. Immunol. 165: 3631-3639.
    • (2000) J. Immunol. , vol.165 , pp. 3631-3639
    • Lee, S.W.1    Song, M.K.2    Back, K.H.3    Park, Y.4    Kim, J.K.5    Lee, C.H.6    Cheong, H.K.7    Cheong, C.8    Sung, Y.C.9
  • 35
    • 0027945606 scopus 로고
    • Binding of oligoguanylate to scavenger receptors is required for oligonucteotides to augment NK cell activity and induce IFN
    • Kimura, Y., K. Sonehara, E. Kuramoto, T. Makino, S. Yamamoto, T. Yamamoto, T. Kataoka, and T. Tokunaga. 1994. Binding of oligoguanylate to scavenger receptors is required for oligonucteotides to augment NK cell activity and induce IFN. J. Biochem. 116: 991-994.
    • (1994) J. Biochem. , vol.116 , pp. 991-994
    • Kimura, Y.1    Sonehara, K.2    Kuramoto, E.3    Makino, T.4    Yamamoto, S.5    Yamamoto, T.6    Kataoka, T.7    Tokunaga, T.8
  • 36
    • 0142039981 scopus 로고    scopus 로고
    • Myeloid differentiation factor 88-dependent post-transcriptional regulation of cyclooxygenase-2 expression by CpG DNA
    • Yeo, S. J., J. G. Yoon, and A. K. Yi. 2003. Myeloid differentiation factor 88-dependent post-transcriptional regulation of cyclooxygenase-2 expression by CpG DNA. J. Biol. Chem, 278: 40590-40600.
    • (2003) J. Biol. Chem. , vol.278 , pp. 40590-40600
    • Yeo, S.J.1    Yoon, J.G.2    Yi, A.K.3
  • 37
    • 0028170124 scopus 로고
    • Three NF-κB sites in the IκB-α promoter are required for induction of gene expression by TNFα
    • Ito, C. Y., A. G. Kazantsev, and S. Baldwin, Jr. 1994. Three NF-κB sites in the IκB-α promoter are required for induction of gene expression by TNFα. Nucleic Acids Res. 22: 3787-3792.
    • (1994) Nucleic Acids Res. , vol.22 , pp. 3787-3792
    • Ito, C.Y.1    Kazantsev, A.G.2    Baldwin Jr., S.3
  • 39
    • 0026590541 scopus 로고
    • Dithiocarbomates as potent inhibitors of nuclear factor κB activation in intact cells
    • Schreck, R., B. Meier, D. N. Mannei, W. Droge, and P. A. Baeurle. 1992. Dithiocarbomates as potent inhibitors of nuclear factor κB activation in intact cells. J. Exp. Med. 175: 1181-1194.
    • (1992) J. Exp. Med. , vol.175 , pp. 1181-1194
    • Schreck, R.1    Meier, B.2    Mannei, D.N.3    Droge, W.4    Baeurle, P.A.5
  • 40
    • 0029810902 scopus 로고    scopus 로고
    • Caffeic acid phenethyl ester is a potent and specific inhibitor of activation of nuclear transcription factor NF-κB
    • Natarajan, K., S. Singh, T. R. Burke, D. Grunberger, and B. B. Aggarwal. 1996. Caffeic acid phenethyl ester is a potent and specific inhibitor of activation of nuclear transcription factor NF-κB. Proc. Natl. Acad. Sci. USA 93: 9090-9095.
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 9090-9095
    • Natarajan, K.1    Singh, S.2    Burke, T.R.3    Grunberger, D.4    Aggarwal, B.B.5
  • 42
    • 20244388983 scopus 로고    scopus 로고
    • Interleukin-1 receptor-associated kinase-1 plays an essential role for Toll-like receptor (TLR)7- and TLR9-mediated interferon-α induction
    • Uematsu, A., S. Sato, M. Yamamoto, T. Hirotani, H. Kato, F. Takeshita, M. Matsuda, C. Coban, K. J. Ishii, T. Kawai, et al. 2005. Interleukin-1 receptor-associated kinase-1 plays an essential role for Toll-like receptor (TLR)7- and TLR9-mediated interferon-α induction. J. Exp. Med. 201: 915-923.
    • (2005) J. Exp. Med. , vol.201 , pp. 915-923
    • Uematsu, A.1    Sato, S.2    Yamamoto, M.3    Hirotani, T.4    Kato, H.5    Takeshita, F.6    Matsuda, M.7    Coban, C.8    Ishii, K.J.9    Kawai, T.10
  • 43
    • 0032524357 scopus 로고    scopus 로고
    • New twists in gene regulation by glucocorticoid receptor: Is DNA binding dispensable?
    • Karin, M. 1998. New twists in gene regulation by glucocorticoid receptor: is DNA binding dispensable? Cell 93: 487-490.
    • (1998) Cell , vol.93 , pp. 487-490
    • Karin, M.1
  • 44
    • 0242668749 scopus 로고    scopus 로고
    • Inhibition of IFN-γ signaling by glucocorticoids
    • Hu, X., W. P. Li, C. Meng, and L. B. Ivashkiv. 2003. Inhibition of IFN-γ signaling by glucocorticoids. J. Immunol 170: 4833-4839.
    • (2003) J. Immunol. , vol.170 , pp. 4833-4839
    • Hu, X.1    Li, W.P.2    Meng, C.3    Ivashkiv, L.B.4
  • 45
    • 0036841288 scopus 로고    scopus 로고
    • Dexamethasone causes sustained expression of mitogen-activated protein kinase (MAPK) phosphatase 1 and phosphatase-mediated inhibition of MAPK p38
    • Lasa, M., S. M. Abraham, C. Boucheron, J. Saklatvala, and A. R. Clark. 2002. Dexamethasone causes sustained expression of mitogen-activated protein kinase (MAPK) phosphatase 1 and phosphatase-mediated inhibition of MAPK p38. Mol. Cell. Biol. 22: 7802-7811.
    • (2002) Mol. Cell. Biol. , vol.22 , pp. 7802-7811
    • Lasa, M.1    Abraham, S.M.2    Boucheron, C.3    Saklatvala, J.4    Clark, A.R.5
  • 47
    • 17844380477 scopus 로고    scopus 로고
    • Spatiotemporal regulation of MyD88-IRF-7 signalling for robust type-I interferon induction
    • Honda, K., Y. Ohba, N. Yanai, H. Negishi, T. Mizutani, A. Takaoka, C. Taya, and T. Taniguchi. 2005. Spatiotemporal regulation of MyD88-IRF-7 signalling for robust type-I interferon induction. Nature 434: 1035-1040.
    • (2005) Nature , vol.434 , pp. 1035-1040
    • Honda, K.1    Ohba, Y.2    Yanai, N.3    Negishi, H.4    Mizutani, T.5    Takaoka, A.6    Taya, C.7    Taniguchi, T.8
  • 48
    • 0030018156 scopus 로고    scopus 로고
    • CC CKR5: A RANTES, MIP-1α, MIP-1β receptor as a fusion cofactor for macrophage-tropic HIV-1
    • Alkhatib, G., C. Combadiere, C. C. Broder, Y. Feng, P. E. Kennedy, P. M. Murphy, and E. A. Berger. 1996. CC CKR5: A RANTES, MIP-1α, MIP-1β receptor as a fusion cofactor for macrophage-tropic HIV-1. Science 272: 1955-1958.
    • (1996) Science , vol.272 , pp. 1955-1958
    • Alkhatib, G.1    Combadiere, C.2    Broder, C.C.3    Feng, Y.4    Kennedy, P.E.5    Murphy, P.M.6    Berger, E.A.7
  • 49
    • 0037443644 scopus 로고    scopus 로고
    • The role of Toll-like receptor 9, Myd88, and DNA-dependent protein kinase catalytic subunit in the effects of two distinct CpG DNAs on dendritic cell subsets
    • Hemmi, H., T. Kaisho, K. Takeda, and S. Akira. 2003. The role of Toll-like receptor 9, Myd88, and DNA-dependent protein kinase catalytic subunit in the effects of two distinct CpG DNAs on dendritic cell subsets. J. Immunol. 170: 3059-3064.
    • (2003) J. Immunol. , vol.170 , pp. 3059-3064
    • Hemmi, H.1    Kaisho, T.2    Takeda, K.3    Akira, S.4
  • 50
    • 0034604623 scopus 로고    scopus 로고
    • Glembotski. p38 MAPK and NF-κB collaborate to induce interleukin-6 gene expression and release: Evidence for a cytoprotective autocrine signaling pathway in a cardiac myocyte model system
    • Craig, R., A. Larkin, M. A. Mingo, D. J. Thuerauf, C. Andrews, P. M. McDonough, and C. Christopher. 2000. Glembotski. p38 MAPK and NF-κB collaborate to induce interleukin-6 gene expression and release: evidence for a cytoprotective autocrine signaling pathway in a cardiac myocyte model system. J. Biol. Chem. 275: 23814-23824.
    • (2000) J. Biol. Chem. , vol.275 , pp. 23814-23824
    • Craig, R.1    Larkin, A.2    Mingo, M.A.3    Thuerauf, D.J.4    Andrews, C.5    McDonough, P.M.6    Christopher, C.7
  • 51
    • 0035379555 scopus 로고    scopus 로고
    • Akt stimulates the transactivation potential of the RelA/p65 subunit of NF-κB through utilization of the IκB kinase and activation of the mitogen-activated protein kinase p38
    • Madrid, L. V., M. W. Mayo, J. Y. Reuuther, and A. S. Baldwin. 2001. Akt stimulates the transactivation potential of the RelA/p65 subunit of NF-κB through utilization of the IκB kinase and activation of the mitogen-activated protein kinase p38. J. Biol. Chem. 276: 18934-18940.
    • (2001) J. Biol. Chem. , vol.276 , pp. 18934-18940
    • Madrid, L.V.1    Mayo, M.W.2    Reuuther, J.Y.3    Baldwin, A.S.4
  • 52
    • 0036143654 scopus 로고    scopus 로고
    • p38-dependent marking of inflammatory genes for increased NF-κB recruitment
    • Saccani, S., S. Pantano, and G. Natoli. 2002. p38-dependent marking of inflammatory genes for increased NF-κB recruitment. Nat. Immunol. 3: 69-75.
    • (2002) Nat. Immunol. , vol.3 , pp. 69-75
    • Saccani, S.1    Pantano, S.2    Natoli, G.3
  • 53
    • 0041832334 scopus 로고    scopus 로고
    • Candida albicans induces selectively transcriptional activation of cyclooxygenase-2 in HeLa cells: Pivotal roles of Toll-like receptors, p38 mitogen-activated protein kinase, and NF-κB
    • Deva, R., P. Shankaranarayanan, R. Ciccoli, and S. Nigam. 2003. Candida albicans induces selectively transcriptional activation of cyclooxygenase-2 in HeLa cells: pivotal roles of Toll-like receptors, p38 mitogen-activated protein kinase, and NF-κB. J. Immunol. 171: 3047-3055.
    • (2003) J. Immunol. , vol.171 , pp. 3047-3055
    • Deva, R.1    Shankaranarayanan, P.2    Ciccoli, R.3    Nigam, S.4
  • 54
    • 0032503045 scopus 로고    scopus 로고
    • The p38-MAPK inhibitor, SB203580, inhibits cardiac stress-activated protein kinases/c-Jun N-terminal kinases (SAPKs/JNKs)
    • Clerk, A., and P. H. Sugden. 1998. The p38-MAPK inhibitor, SB203580, inhibits cardiac stress-activated protein kinases/c-Jun N-terminal kinases (SAPKs/JNKs). FEBS Lett. 426: 93-96.
    • (1998) FEBS Lett. , vol.426 , pp. 93-96
    • Clerk, A.1    Sugden, P.H.2
  • 55
    • 0034629345 scopus 로고    scopus 로고
    • The pyridinyl imidazole inhibitor SB203580 blocks phosphoinositide- dependent protein kinase activity, protein kinase B phosphorylation, and retinoblastoma hyperphosphorylation in interleukin-2-stimulated T cells independently of p38 mitogen-activated protein kinase
    • Lali, F. V., A. E. Hunt, S. J. Turner, and B. M. J. Foxwell. 2000. The pyridinyl imidazole inhibitor SB203580 blocks phosphoinositide-dependent protein kinase activity, protein kinase B phosphorylation, and retinoblastoma hyperphosphorylation in interleukin-2-stimulated T cells independently of p38 mitogen-activated protein kinase. J. Biol. Chem. 275: 7395-7402.
    • (2000) J. Biol. Chem. , vol.275 , pp. 7395-7402
    • Lali, F.V.1    Hunt, A.E.2    Turner, S.J.3    Foxwell, B.M.J.4
  • 56
    • 0034053445 scopus 로고    scopus 로고
    • Reconstitution of virus-mediated expression of interferon α gene in human fibroblast cells by ectopic interferon regulatory factor-7
    • Yeow, W., W. Au, Y. Jauang, C. D. Fields, C. L. Dent, D. R. Gewert, and P. M. Pitha. 2000. Reconstitution of virus-mediated expression of interferon α gene in human fibroblast cells by ectopic interferon regulatory factor-7. J. Biol. Chem. 275: 6313-6320.
    • (2000) J. Biol. Chem. , vol.275 , pp. 6313-6320
    • Yeow, W.1    Au, W.2    Jauang, Y.3    Fields, C.D.4    Dent, C.L.5    Gewert, D.R.6    Pitha, P.M.7
  • 57
    • 0032538891 scopus 로고    scopus 로고
    • Differential viral induction of distinct interferon-α genes by positive feedback through interferon regulatory factor-7
    • Marie, I., J. E. Durbin, and D. E. Levy. 1998. Differential viral induction of distinct interferon-α genes by positive feedback through interferon regulatory factor-7. EMBO J. 17: 6660-6669.
    • (1998) EMBO J. , vol.17 , pp. 6660-6669
    • Marie, I.1    Durbin, J.E.2    Levy, D.E.3
  • 58
    • 0034327721 scopus 로고    scopus 로고
    • IFN-α suppresses activation of nuclear transcription factors NF-κB and activator protein 1 and potentiates TNF-induced apoptpsos
    • Manna, S. K., A. Mukhopadhyay, and B. B. Aggarwal. 2000. IFN-α suppresses activation of nuclear transcription factors NF-κB and activator protein 1 and potentiates TNF-induced apoptpsos. J. Immunol. 165: 4927-4934.
    • (2000) J. Immunol. , vol.165 , pp. 4927-4934
    • Manna, S.K.1    Mukhopadhyay, A.2    Aggarwal, B.B.3
  • 59
    • 1842631153 scopus 로고    scopus 로고
    • Immunotherapeutic uses of CpG oligodeoxynucleotides
    • Klinman, D. M. 2004. Immunotherapeutic uses of CpG oligodeoxynucleotides. Nat. Rev. Immunol. 4: 249-258.
    • (2004) Nat. Rev. Immunol. , vol.4 , pp. 249-258
    • Klinman, D.M.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.