Structure-specific effects of protein topology on cross-β assembly: Studies of insulin fibrillation

Biochemistry

Volumn 45, Issue 34, 2006, Pages 10278-10293

  Huang, Kun ^a   Maiti, Nakul C ^a   Phillips, Nelson B ^a   Carey, Paul R ^a   Weiss, Michael A ^a  

^a CASE WESTERN RESERVE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMORPHOUS MATERIALS; BIOCHEMISTRY; CROSSLINKING; INSULIN; POLYPEPTIDES; PRECIPITATION (CHEMICAL);

FIBRILLATION; ISOMERIC FIBRILS; PROTEIN EVOLUTION; PROTEIN TOPOLOGY;

ENZYMES;

DISULFIDE; GLOBULAR PROTEIN; HUMAN INSULIN; INSULIN; PROINSULIN;

AMYLOIDOSIS; ARTICLE; CIRCULAR DICHROISM; CRYSTAL STRUCTURE; FLUORESCENCE SPECTROSCOPY; ISOMER; MORPHOLOGY; PRIORITY JOURNAL; PROTEIN ASSEMBLY; PROTEIN FOLDING; RAMAN SPECTROMETRY; STRUCTURE ANALYSIS; THERMODYNAMICS; TRANSMISSION ELECTRON MICROSCOPY;

AMYLOID; AMYLOIDOSIS; HUMANS; MODELS, CHEMICAL; PROINSULIN; PROTEIN DENATURATION; PROTEIN FOLDING; PROTEIN STRUCTURE, SECONDARY; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 33748660053     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi060879g     Document Type: Article

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