Aβ40-lactam(D23/K28) models a conformation highly favorable for nucleation of amyloid

Biochemistry

Volumn 44, Issue 16, 2005, Pages 6003-6014

  Sciarretta, Kimberly L ^a   Gordon, David J ^a   Petkova, Aneta T ^b   Tycko, Robert ^b   Meredith, Stephen C ^a  

^a UNIVERSITY OF CHICAGO   (United States)

^b NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BAND STRUCTURE; CONCENTRATION (PROCESS); MATHEMATICAL MODELS; NUCLEAR MAGNETIC RESONANCE; NUCLEATION; OLIGOMERS; POLYPEPTIDES; SYNTHESIS (CHEMICAL);

AMYLOID FIBRILS; BEND STRUCTURE; SOLID STATE;

BIOPOLYMERS;

AMYLOID; ASPARTYLVALYLGLYCYLSERYLASPARGINYLLYSYLGLYCYL; GLYCINE DERIVATIVE; LACTAM; LACTAM DERIVATIVE; OLIGOMER; UNCLASSIFIED DRUG; AMYLOID BETA PROTEIN; AMYLOID BETA PROTEIN[1-40]; MULTIPROTEIN COMPLEX; PEPTIDE FRAGMENT;

ARTICLE; BETA SHEET; CONTROLLED STUDY; GEL PERMEATION CHROMATOGRAPHY; NONHUMAN; NUCLEAR MAGNETIC RESONANCE; OLIGOMERIZATION; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN SYNTHESIS; AMINO ACID SEQUENCE; CHEMICAL STRUCTURE; CHEMISTRY; ELECTRON MICROSCOPY; HUMAN; IN VITRO STUDY; KINETICS; METABOLISM; MOLECULAR GENETICS; SPECTROPHOTOMETRY; SYNTHESIS; ULTRASTRUCTURE;

AMINO ACID SEQUENCE; AMYLOID; AMYLOID BETA-PROTEIN; HUMANS; KINETICS; LACTAMS; MICROSCOPY, ELECTRON; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MULTIPROTEIN COMPLEXES; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; PEPTIDE FRAGMENTS; PROTEIN CONFORMATION; SPECTROPHOTOMETRY;

EID: 17644397372     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi0474867     Document Type: Article

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