-
1
-
-
32944464648
-
Pathogen recognition and innate immunity
-
Akira S, Uematsu S, and Takeuchi O. Pathogen recognition and innate immunity. Cell 124: 783-801, 2006.
-
(2006)
Cell
, vol.124
, pp. 783-801
-
-
Akira, S.1
Uematsu, S.2
Takeuchi, O.3
-
2
-
-
0035909372
-
Recognition of double-stranded RNA and activation of NF-κB by Toll-like receptor 3
-
Alexopoulou L, Holt AC, Medzhitov R, and Flavell RA. Recognition of double-stranded RNA and activation of NF-κB by Toll-like receptor 3. Nature 413: 732-738, 2001.
-
(2001)
Nature
, vol.413
, pp. 732-738
-
-
Alexopoulou, L.1
Holt, A.C.2
Medzhitov, R.3
Flavell, R.A.4
-
3
-
-
0037307507
-
Bacterial CpG-DNA aggravates immune complex glomerulonephritis: Role of TLR9-mediated expression of chemokines and chemokine receptors
-
Anders HJ, Banas B, Linde Y, Weller L, Cohen CD, Kretzler M, Martin S, Vielhauer V, Schlöndorff D, and Gröne HJ. Bacterial CpG-DNA aggravates immune complex glomerulonephritis: role of TLR9-mediated expression of chemokines and chemokine receptors. J Am Soc Nephrol 14: 317-326, 2003.
-
(2003)
J Am Soc Nephrol
, vol.14
, pp. 317-326
-
-
Anders, H.J.1
Banas, B.2
Linde, Y.3
Weller, L.4
Cohen, C.D.5
Kretzler, M.6
Martin, S.7
Vielhauer, V.8
Schlöndorff, D.9
Gröne, H.J.10
-
4
-
-
1642275654
-
Signaling danger: Toll-like receptors and their potential roles in kidney disease
-
Anders HJ, Banas B, and Schlöndorff D. Signaling danger: toll-like receptors and their potential roles in kidney disease. J Am Soc Nephrol 15: 854-867, 2004.
-
(2004)
J Am Soc Nephrol
, vol.15
, pp. 854-867
-
-
Anders, H.J.1
Banas, B.2
Schlöndorff, D.3
-
5
-
-
1642396952
-
Activation of toll-like receptor-9 induces progression of renal disease in MRL-Fas(lpr) mice
-
Anders HJ, Vielhauer V, Eis V, Linde Y, Kretzler M, Perez de Lema G, Strutz F, Bauer S, Rutz M, Wagner H, Gröne HJ, and Schlöndorff D. Activation of toll-like receptor-9 induces progression of renal disease in MRL-Fas(lpr) mice. FASEB J 18: 534-536, 2004.
-
(2004)
FASEB J
, vol.18
, pp. 534-536
-
-
Anders, H.J.1
Vielhauer, V.2
Eis, V.3
Linde, Y.4
Kretzler, M.5
Perez De Lema, G.6
Strutz, F.7
Bauer, S.8
Rutz, M.9
Wagner, H.10
Gröne, H.J.11
Schlöndorff, D.12
-
6
-
-
0036735155
-
Variable expression of Toll-like receptor in murine innate and adaptive immune cell lines
-
Applequist SE, Wallin RP, and Ljunggren HG. Variable expression of Toll-like receptor in murine innate and adaptive immune cell lines. Int Immunol 14: 1065-1074, 2002.
-
(2002)
Int Immunol
, vol.14
, pp. 1065-1074
-
-
Applequist, S.E.1
Wallin, R.P.2
Ljunggren, H.G.3
-
7
-
-
17644405409
-
Sequence requirements for oligodeoxyribonucleotide inhibitory activity
-
Ashman RF, Goeken JA, Drahos J, and Lenert P. Sequence requirements for oligodeoxyribonucleotide inhibitory activity. Int Immunol 17: 411-420, 2005.
-
(2005)
Int Immunol
, vol.17
, pp. 411-420
-
-
Ashman, R.F.1
Goeken, J.A.2
Drahos, J.3
Lenert, P.4
-
8
-
-
29244450802
-
Intracellular localization of Toll-like receptor 9 prevents recognition of self DNA but facilitates access to viral DNA
-
Barton GM, Kagan JC, and Medzhitov R. Intracellular localization of Toll-like receptor 9 prevents recognition of self DNA but facilitates access to viral DNA. Nat Immunol 7: 49-56, 2006.
-
(2006)
Nat Immunol
, vol.7
, pp. 49-56
-
-
Barton, G.M.1
Kagan, J.C.2
Medzhitov, R.3
-
9
-
-
0036839577
-
Endogenous ligands of Toll-like receptors: Implications for regulating inflammatory and immune responses
-
Beg AA. Endogenous ligands of Toll-like receptors: implications for regulating inflammatory and immune responses. Trends Immunol 23: 509-512, 2002.
-
(2002)
Trends Immunol
, vol.23
, pp. 509-512
-
-
Beg, A.A.1
-
10
-
-
15444364398
-
Plasmacytoid dendritic cells control TLR7 sensitivity of naive B cells via type I IFN
-
Bekeredjian-Ding IB, Wagner M, Hornung V, Giese T, Schnurr M, Endres S, and Hartmann G. Plasmacytoid dendritic cells control TLR7 sensitivity of naive B cells via type I IFN. J Immunol 174: 4043-4050, 2005.
-
(2005)
J Immunol
, vol.174
, pp. 4043-4050
-
-
Bekeredjian-Ding, I.B.1
Wagner, M.2
Hornung, V.3
Giese, T.4
Schnurr, M.5
Endres, S.6
Hartmann, G.7
-
11
-
-
0036453721
-
Evolution of the TIR, tolls and TLRs: Functional inferences from computational biology
-
Beutler B and Rehli M. Evolution of the TIR, tolls and TLRs: functional inferences from computational biology. Curr Top Microbiol Immunol 270: 1-21, 2002.
-
(2002)
Curr Top Microbiol Immunol
, vol.270
, pp. 1-21
-
-
Beutler, B.1
Rehli, M.2
-
12
-
-
25444443335
-
RNA released from necrotic synovial fluid cells activates rheumatoid arthritis synovial fibroblasts via Toll-like receptor 3
-
Brentano F, Schorr O, Gay RE, Gay S, and Kyburz D. RNA released from necrotic synovial fluid cells activates rheumatoid arthritis synovial fibroblasts via Toll-like receptor 3. Arthritis Rheum 52: 2656-2665, 2005.
-
(2005)
Arthritis Rheum
, vol.52
, pp. 2656-2665
-
-
Brentano, F.1
Schorr, O.2
Gay, R.E.3
Gay, S.4
Kyburz, D.5
-
14
-
-
22944490869
-
Toll-like receptor 9 controls anti-DNA autoantibody production in murine lupus
-
Christensen SR, Kashgarian M, Alexopoulou L, Flavell RA, Akira S, and Shlomchik MJ. Toll-like receptor 9 controls anti-DNA autoantibody production in murine lupus. J Exp Med 202: 321-331, 2005.
-
(2005)
J Exp Med
, vol.202
, pp. 321-331
-
-
Christensen, S.R.1
Kashgarian, M.2
Alexopoulou, L.3
Flavell, R.A.4
Akira, S.5
Shlomchik, M.J.6
-
15
-
-
0034457684
-
Cloning and characterization of a subfamily of human toll-like receptors: hTLR7, hTLR8 and hTLR9
-
Chuang TH and Ulevitch RJ. Cloning and characterization of a subfamily of human toll-like receptors: hTLR7, hTLR8 and hTLR9. Eur Cytokine Netw 11: 372-378, 2000.
-
(2000)
Eur Cytokine Netw
, vol.11
, pp. 372-378
-
-
Chuang, T.H.1
Ulevitch, R.J.2
-
16
-
-
2342623292
-
TLR7: A new sensor of viral infection
-
Crozat K and Beutler B. TLR7: a new sensor of viral infection. Proc Natl Acad Sci USA 101: 6835-6836, 2004.
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 6835-6836
-
-
Crozat, K.1
Beutler, B.2
-
17
-
-
1542317550
-
Innate antiviral responses by means of TLR7-mediated recognition of single-stranded RNA
-
Diebold SS, Kaisho T, Hemmi H, Akira S, and Reis e Sousa C. Innate antiviral responses by means of TLR7-mediated recognition of single-stranded RNA. Science 303: 1529-1531, 2004.
-
(2004)
Science
, vol.303
, pp. 1529-1531
-
-
Diebold, S.S.1
Kaisho, T.2
Hemmi, H.3
Akira, S.4
Reis E Sousa, C.5
-
18
-
-
13444302229
-
Suppressive oligodeoxynucleotides delay the onset of glomerulonephritis and prolong survival in lupus-prone NZB x NZW mice
-
Dong L, Ito S, Ishii KJ, and Klinman DM. Suppressive oligodeoxynucleotides delay the onset of glomerulonephritis and prolong survival in lupus-prone NZB x NZW mice. Arthritis Rheum 52: 651-658, 2005.
-
(2005)
Arthritis Rheum
, vol.52
, pp. 651-658
-
-
Dong, L.1
Ito, S.2
Ishii, K.J.3
Klinman, D.M.4
-
19
-
-
0034456693
-
Three novel mammalian toll-like receptors: Gene structure, expression, and evolution
-
Du X, Poltorak A, Wei Y, and Beutler B. Three novel mammalian toll-like receptors: gene structure, expression, and evolution. Eur Cytokine Netw 11: 362-371, 2000.
-
(2000)
Eur Cytokine Netw
, vol.11
, pp. 362-371
-
-
Du, X.1
Poltorak, A.2
Wei, Y.3
Beutler, B.4
-
20
-
-
1942521223
-
Does Toll-like receptor 3 play a biological role in virus infections?
-
Edelmann KH, Richardson-Burns S, Alexopoulou L, Tyler KL, Flavell RA, and Oldstone MB. Does Toll-like receptor 3 play a biological role in virus infections? Virology 322: 231-238, 2004.
-
(2004)
Virology
, vol.322
, pp. 231-238
-
-
Edelmann, K.H.1
Richardson-Burns, S.2
Alexopoulou, L.3
Tyler, K.L.4
Flavell, R.A.5
Oldstone, M.B.6
-
21
-
-
0037738569
-
+ DC correlates with unresponsiveness to imidazoquinolines
-
+ DC correlates with unresponsiveness to imidazoquinolines. Eur J Immunol 33: 827-833, 2003.
-
(2003)
Eur J Immunol
, vol.33
, pp. 827-833
-
-
Edwards, A.D.1
Diebold, S.S.2
Slack, E.M.3
Tomizawa, H.4
Hemmi, H.5
Kaisho, T.6
Akira, S.7
Reis E Sousa, C.8
-
22
-
-
0037974914
-
Critical role of the Toll-like receptor signal adaptor protein MyD88 in acute allograft rejection
-
Goldstein DR, Tesar BM, Akira S, and Lakkis FG. Critical role of the Toll-like receptor signal adaptor protein MyD88 in acute allograft rejection. J Clin Invest 111: 1571-1578, 2003.
-
(2003)
J Clin Invest
, vol.111
, pp. 1571-1578
-
-
Goldstein, D.R.1
Tesar, B.M.2
Akira, S.3
Lakkis, F.G.4
-
23
-
-
2442605662
-
Mechanisms of the TRIF-induced interferon-stimulated response element and NF-κB activation and apoptosis pathways
-
Han KJ, Su X, Xu LG, Bin LH, Zhang J, and Shu HB. Mechanisms of the TRIF-induced interferon-stimulated response element and NF-κB activation and apoptosis pathways. J Biol Chem 279: 15652-15661, 2004.
-
(2004)
J Biol Chem
, vol.279
, pp. 15652-15661
-
-
Han, K.J.1
Su, X.2
Xu, L.G.3
Bin, L.H.4
Zhang, J.5
Shu, H.B.6
-
25
-
-
0842343142
-
Lymphoid follicle destruction and immunosuppression after repeated CpG oligodeoxynucleotide administration
-
Heikenwalder M, Polymenidou M, Junt T, Sigurdson C, Wagner H, Akira S, Zinkernagel R, and Aguzzi A. Lymphoid follicle destruction and immunosuppression after repeated CpG oligodeoxynucleotide administration. Nat Med 10: 187-192, 2004.
-
(2004)
Nat Med
, vol.10
, pp. 187-192
-
-
Heikenwalder, M.1
Polymenidou, M.2
Junt, T.3
Sigurdson, C.4
Wagner, H.5
Akira, S.6
Zinkernagel, R.7
Aguzzi, A.8
-
26
-
-
1542317578
-
Species-specific recognition of single-stranded RNA via toll-like receptor 7 and 8
-
Heil F, Hemmi H, Hochrein H, Ampenberger F, Kirschning C, Akira S, Lipford G, Wagner H, and Bauer S. Species-specific recognition of single-stranded RNA via toll-like receptor 7 and 8. Science 303: 1526-1529, 2004.
-
(2004)
Science
, vol.303
, pp. 1526-1529
-
-
Heil, F.1
Hemmi, H.2
Hochrein, H.3
Ampenberger, F.4
Kirschning, C.5
Akira, S.6
Lipford, G.7
Wagner, H.8
Bauer, S.9
-
27
-
-
0037484345
-
Species-specific regulation of Toll-like receptor 3 genes in men and mice
-
Heinz S, Haehnel V, Karaghiosoff M, Schwarzfischer L, Muller M, Krause SW, and Rehli M. Species-specific regulation of Toll-like receptor 3 genes in men and mice. J Biol Chem 278: 21502-21509, 2003.
-
(2003)
J Biol Chem
, vol.278
, pp. 21502-21509
-
-
Heinz, S.1
Haehnel, V.2
Karaghiosoff, M.3
Schwarzfischer, L.4
Muller, M.5
Krause, S.W.6
Rehli, M.7
-
28
-
-
1642566833
-
CpG-DNA aided cross-priming by cross-presenting B cells
-
Heit A, Huster KM, Schmitz F, Schiemann M, Busch DH, and Wagner H. CpG-DNA aided cross-priming by cross-presenting B cells. J Immunol 172: 1501-1507, 2004.
-
(2004)
J Immunol
, vol.172
, pp. 1501-1507
-
-
Heit, A.1
Huster, K.M.2
Schmitz, F.3
Schiemann, M.4
Busch, D.H.5
Wagner, H.6
-
29
-
-
0036008014
-
Small anti-viral compounds activate immune cells via the TLR7 MyD88-dependent signaling pathway
-
Hemmi H, Kaisho T, Takeuchi O, Sato S, Sanjo H, Hoshino K, Horiuchi T, Tomizawa H, Takeda K, and Akira S. Small anti-viral compounds activate immune cells via the TLR7 MyD88-dependent signaling pathway. Nat Immunol 3: 196-200, 2002.
-
(2002)
Nat Immunol
, vol.3
, pp. 196-200
-
-
Hemmi, H.1
Kaisho, T.2
Takeuchi, O.3
Sato, S.4
Sanjo, H.5
Hoshino, K.6
Horiuchi, T.7
Tomizawa, H.8
Takeda, K.9
Akira, S.10
-
30
-
-
0034619794
-
A Toll-like receptor recognizes bacterial DNA
-
Hemmi H, Takeuchi O, Kawai T, Kaisho T, Sato S, Sanjo H, Matsumoto M, Hoshino K, Wagner H, Takeda K, and Akira S. A Toll-like receptor recognizes bacterial DNA. Nature 408: 740-745, 2000.
-
(2000)
Nature
, vol.408
, pp. 740-745
-
-
Hemmi, H.1
Takeuchi, O.2
Kawai, T.3
Kaisho, T.4
Sato, S.5
Sanjo, H.6
Matsumoto, M.7
Hoshino, K.8
Wagner, H.9
Takeda, K.10
Akira, S.11
-
31
-
-
0036570169
-
Quantitative expression of toll-like receptor 1-10 mRNA in cellular subsets of human peripheral blood mononuclear cells and sensitivity to CpG oligodeoxynucleotides
-
Hornung V, Rothenfusser S, Britsch S, Krug A, Jahrsdorfer B, Giese T, Endres S, and Hartmann G. Quantitative expression of toll-like receptor 1-10 mRNA in cellular subsets of human peripheral blood mononuclear cells and sensitivity to CpG oligodeoxynucleotides. J Immunol 168: 4531-4537, 2002.
-
(2002)
J Immunol
, vol.168
, pp. 4531-4537
-
-
Hornung, V.1
Rothenfusser, S.2
Britsch, S.3
Krug, A.4
Jahrsdorfer, B.5
Giese, T.6
Endres, S.7
Hartmann, G.8
-
32
-
-
0036721808
-
Activation of APCs through CD40 or Toll-like receptor 9 overcomes tolerance and precipitates autoimmune disease
-
Ichikawa HT, Williams LP, and Segal BM. Activation of APCs through CD40 or Toll-like receptor 9 overcomes tolerance and precipitates autoimmune disease. J Immunol 169: 2781-2787, 2002.
-
(2002)
J Immunol
, vol.169
, pp. 2781-2787
-
-
Ichikawa, H.T.1
Williams, L.P.2
Segal, B.M.3
-
33
-
-
0027393927
-
Membranoproliferative glomerulonephritis associated with hepatitis C virus infection
-
Johnson RJ, Gretch DR, Yamabe H, Hart J, Bacchi CE, Hartwell P, Couser WG, Corey L, Wener MH, Alpers CE, and Willson R. Membranoproliferative glomerulonephritis associated with hepatitis C virus infection. N Engl J Med 328: 465-470, 1993.
-
(1993)
N Engl J Med
, vol.328
, pp. 465-470
-
-
Johnson, R.J.1
Gretch, D.R.2
Yamabe, H.3
Hart, J.4
Bacchi, C.E.5
Hartwell, P.6
Couser, W.G.7
Corey, L.8
Wener, M.H.9
Alpers, C.E.10
Willson, R.11
-
34
-
-
0348135024
-
Dendritic-cell control of pathogen-driven T-cell polarization
-
Kapsenberg ML. Dendritic-cell control of pathogen-driven T-cell polarization. Nat Rev Immunol 3: 984-993, 2003.
-
(2003)
Nat Rev Immunol
, vol.3
, pp. 984-993
-
-
Kapsenberg, M.L.1
-
35
-
-
2442705429
-
Small interfering RNAs mediate sequence-independent gene suppression and induce immune activation by signalling through toll-like receptor 3
-
Kariko K, Bhuyan P, Capodici J, and Weissman D. Small interfering RNAs mediate sequence-independent gene suppression and induce immune activation by signalling through toll-like receptor 3. J Immunol 172: 6545-6549, 2004.
-
(2004)
J Immunol
, vol.172
, pp. 6545-6549
-
-
Kariko, K.1
Bhuyan, P.2
Capodici, J.3
Weissman, D.4
-
36
-
-
1842477469
-
mRNA is an endogenous ligand for Toll-like receptor 3
-
Kariko K, Ni H, Capodici J, Lamphier M, and Weissman D. mRNA is an endogenous ligand for Toll-like receptor 3. J Biol Chem 279: 12542-12550, 2004.
-
(2004)
J Biol Chem
, vol.279
, pp. 12542-12550
-
-
Kariko, K.1
Ni, H.2
Capodici, J.3
Lamphier, M.4
Weissman, D.5
-
37
-
-
0041883736
-
An update on herpes virus infections in graft recipients
-
Ketteler M, Kunter U, and Floege J. An update on herpes virus infections in graft recipients. Nephrol Dial Transplant 18: 1703-1706, 2003.
-
(2003)
Nephrol Dial Transplant
, vol.18
, pp. 1703-1706
-
-
Ketteler, M.1
Kunter, U.2
Floege, J.3
-
38
-
-
0036219195
-
CpG motifs in bacterial DNA and their immune effects
-
Krieg AM. CpG motifs in bacterial DNA and their immune effects. Annu Rev Immunol 20: 709-760, 2002.
-
(2002)
Annu Rev Immunol
, vol.20
, pp. 709-760
-
-
Krieg, A.M.1
-
39
-
-
0028931102
-
CpG motifs in bacterial DNA trigger direct B-cell activation
-
Krieg AM, Yi AK, Matson S, Waldschmidt TJ, Bishop GA, Teasdale R, Koretzky GA, and Klinman DM. CpG motifs in bacterial DNA trigger direct B-cell activation. Nature 374: 546-549, 1995.
-
(1995)
Nature
, vol.374
, pp. 546-549
-
-
Krieg, A.M.1
Yi, A.K.2
Matson, S.3
Waldschmidt, T.J.4
Bishop, G.A.5
Teasdale, R.6
Koretzky, G.A.7
Klinman, D.M.8
-
40
-
-
10744219675
-
TLR9 signals after translocating from the ER to CpG DNA in the lysosome
-
Latz E, Schoenemeyer A, Visintin A, Fitzgerald KA, Monks BG, Knetter CF, Lien E, Nilsen NJ, Espevik T, and Golenbock DT. TLR9 signals after translocating from the ER to CpG DNA in the lysosome. Nat Immunol 5: 190-198, 2004.
-
(2004)
Nat Immunol
, vol.5
, pp. 190-198
-
-
Latz, E.1
Schoenemeyer, A.2
Visintin, A.3
Fitzgerald, K.A.4
Monks, B.G.5
Knetter, C.F.6
Lien, E.7
Nilsen, N.J.8
Espevik, T.9
Golenbock, D.T.10
-
41
-
-
0037061453
-
Chromatin-IgG complexes activate B cells by dual engagement of IgM and Toll-like receptors
-
Leadbetter EA, Rifkin IR, Hohlbaum AM, Beaudette BC, Shlomchik MJ, and Marshak-Rothstein A. Chromatin-IgG complexes activate B cells by dual engagement of IgM and Toll-like receptors. Nature 416: 603-607, 2002.
-
(2002)
Nature
, vol.416
, pp. 603-607
-
-
Leadbetter, E.A.1
Rifkin, I.R.2
Hohlbaum, A.M.3
Beaudette, B.C.4
Shlomchik, M.J.5
Marshak-Rothstein, A.6
-
42
-
-
3142691844
-
The road to Toll
-
Lemaitre B. The road to Toll. Nat Rev Immunol 4: 521-527, 2004.
-
(2004)
Nat Rev Immunol
, vol.4
, pp. 521-527
-
-
Lemaitre, B.1
-
43
-
-
0030595339
-
The dorsoventral regulatory gene cassette spatzle/Toll/cactus controls the potent antifungal response in Drosophila adults
-
Lemaitre B, Nicolas E, Michaut L, Reichhart JM, and Hoffmann JA. The dorsoventral regulatory gene cassette spatzle/Toll/cactus controls the potent antifungal response in Drosophila adults. Cell 86: 973-983, 1996.
-
(1996)
Cell
, vol.86
, pp. 973-983
-
-
Lemaitre, B.1
Nicolas, E.2
Michaut, L.3
Reichhart, J.M.4
Hoffmann, J.A.5
-
44
-
-
16244423314
-
Inhibitory oligodeoxynucleotides - Therapeutic promise for systemic autoimmune diseases?
-
Lenert P. Inhibitory oligodeoxynucleotides - therapeutic promise for systemic autoimmune diseases? Clin Exp Immunol 140: 1-10, 2005.
-
(2005)
Clin Exp Immunol
, vol.140
, pp. 1-10
-
-
Lenert, P.1
-
45
-
-
0141923686
-
Toll-like receptor ligands modulate dendritic cells to augment cytomegalovirus- and HIV-1-specific T cell responses
-
Lore K, Betts MR, Brenchley JM, Kuruppu J, Khojasteh S, Perfetto S, Roederer M, Seder RA, and Koup RA. Toll-like receptor ligands modulate dendritic cells to augment cytomegalovirus- and HIV-1-specific T cell responses. J Immunol 171: 4320-4328, 2003.
-
(2003)
J Immunol
, vol.171
, pp. 4320-4328
-
-
Lore, K.1
Betts, M.R.2
Brenchley, J.M.3
Kuruppu, J.4
Khojasteh, S.5
Perfetto, S.6
Roederer, M.7
Seder, R.A.8
Koup, R.A.9
-
46
-
-
1842631428
-
Recognition of single-stranded RNA viruses by Toll-like receptor 7
-
Lund JM, Alexopoulou L, Sato A, Karow M, Adams NC, Gale NW, Iwasaki A, and Flavell RA. Recognition of single-stranded RNA viruses by Toll-like receptor 7. Proc Natl Acad Sci USA 101: 5598-5603, 2004.
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 5598-5603
-
-
Lund, J.M.1
Alexopoulou, L.2
Sato, A.3
Karow, M.4
Adams, N.C.5
Gale, N.W.6
Iwasaki, A.7
Flavell, R.A.8
-
47
-
-
0036100526
-
Replication and compartmentalization of HIV-1 in kidney epithelium of patients with HIV-associated nephropathy
-
Marras D, Bruggeman LA, Gao F, Tanji N, Mansukhani MM, Cara A, Ross MD, Gusella GL, Benson G, D'Agati VD, Hahn BH, Klotman ME, and Klotman PE. Replication and compartmentalization of HIV-1 in kidney epithelium of patients with HIV-associated nephropathy. Nat Med 8: 522-526, 2002.
-
(2002)
Nat Med
, vol.8
, pp. 522-526
-
-
Marras, D.1
Bruggeman, L.A.2
Gao, F.3
Tanji, N.4
Mansukhani, M.M.5
Cara, A.6
Ross, M.D.7
Gusella, G.L.8
Benson, G.9
D'Agati, V.D.10
Hahn, B.H.11
Klotman, M.E.12
Klotman, P.E.13
-
48
-
-
1642422416
-
Toll-like receptor 3: A link between toll-like receptor, interferon and viruses
-
Matsumoto M, Funami K, Oshiumi H, and Seya T. Toll-like receptor 3: a link between toll-like receptor, interferon and viruses. Microbiol Immunol 48: 147-154, 2004.
-
(2004)
Microbiol Immunol
, vol.48
, pp. 147-154
-
-
Matsumoto, M.1
Funami, K.2
Oshiumi, H.3
Seya, T.4
-
49
-
-
0037066427
-
The danger model: A renewed sense of self
-
Matzinger P. The danger model: a renewed sense of self. Science 296: 301-305, 2002.
-
(2002)
Science
, vol.296
, pp. 301-305
-
-
Matzinger, P.1
-
50
-
-
2442642691
-
RIP1 is an essential mediator of Toll-like receptor 3-induced NF-κB activation
-
Meylan E, Burns K, Hofmann K, Blancheteau V, Martinon F, Kelliher M, and Tschopp J. RIP1 is an essential mediator of Toll-like receptor 3-induced NF-κB activation. Nat Immunol 5: 503-507, 2004.
-
(2004)
Nat Immunol
, vol.5
, pp. 503-507
-
-
Meylan, E.1
Burns, K.2
Hofmann, K.3
Blancheteau, V.4
Martinon, F.5
Kelliher, M.6
Tschopp, J.7
-
51
-
-
0033758480
-
Unmethylated oligo-DNA containing CpG motifs aggravates collagen-induced arthritis in mice
-
Miyata M, Kobayashi H, Sasajima T, Sato Y, and Kasukawa R. Unmethylated oligo-DNA containing CpG motifs aggravates collagen-induced arthritis in mice. Arthritis Rheum 43: 2578-2582, 2000.
-
(2000)
Arthritis Rheum
, vol.43
, pp. 2578-2582
-
-
Miyata, M.1
Kobayashi, H.2
Sasajima, T.3
Sato, Y.4
Kasukawa, R.5
-
52
-
-
1842631428
-
Recognition of single-stranded RNA viruses by Toll-like receptor 7
-
Nagase H, Okugawa S, Ota Y, Yamaguchi M, Tomizawa H, Matsushima K, Ohta K, Yamamoto K, and Hirai K. Recognition of single-stranded RNA viruses by Toll-like receptor 7. Proc Natl Acad Sci USA 101: 5598-5603, 2004.
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 5598-5603
-
-
Nagase, H.1
Okugawa, S.2
Ota, Y.3
Yamaguchi, M.4
Tomizawa, H.5
Matsushima, K.6
Ohta, K.7
Yamamoto, K.8
Hirai, K.9
-
53
-
-
23944489407
-
Selected Toll-like receptor agonist combinations synergistically trigger a T helper type 1-polarizing program in dendritic cells
-
Napolitani G, Rinaldi A, Bertoni F, Sallusto F, and Lanzavecchia A. Selected Toll-like receptor agonist combinations synergistically trigger a T helper type 1-polarizing program in dendritic cells. Nat Immunol 6: 769-776, 2005.
-
(2005)
Nat Immunol
, vol.6
, pp. 769-776
-
-
Napolitani, G.1
Rinaldi, A.2
Bertoni, F.3
Sallusto, F.4
Lanzavecchia, A.5
-
54
-
-
23944497673
-
Viral double-stranded RNA aggravates lupus nephritis through Toll-like receptor-3 on glomerular mesangial cells and antigen-presenting cells
-
Patole P, Gröne HJ, Segerer S, Ciubar R, Belemezova E, Henger A, Kretzler M, Schlöndorff D, and Anders HJ. Viral double-stranded RNA aggravates lupus nephritis through Toll-like receptor-3 on glomerular mesangial cells and antigen-presenting cells. J Am Soc Nephrol 16: 1326-1338, 2005.
-
(2005)
J Am Soc Nephrol
, vol.16
, pp. 1326-1338
-
-
Patole, P.1
Gröne, H.J.2
Segerer, S.3
Ciubar, R.4
Belemezova, E.5
Henger, A.6
Kretzler, M.7
Schlöndorff, D.8
Anders, H.J.9
-
55
-
-
33144458473
-
G-rich DNA suppresses systemic lupus
-
Patole P, Zecher D, Pawar RD, Gröne HJ, Schlöndorff D, and Anders HJ. G-rich DNA suppresses systemic lupus. J Am Soc Nephrol 16: 3273-3280, 2005.
-
(2005)
J Am Soc Nephrol
, vol.16
, pp. 3273-3280
-
-
Patole, P.1
Zecher, D.2
Pawar, R.D.3
Gröne, H.J.4
Schlöndorff, D.5
Anders, H.J.6
-
56
-
-
33644515263
-
Toll-like receptor-7 modulates immune complex glomerulonephritis
-
Pawar RD, Patole PS, Zecher D, Kretzler M, Schlöndorff D, and Anders HJ. Toll-like receptor-7 modulates immune complex glomerulonephritis. J Am Soc Nephrol 17: 141-149, 2006.
-
(2006)
J Am Soc Nephrol
, vol.17
, pp. 141-149
-
-
Pawar, R.D.1
Patole, P.S.2
Zecher, D.3
Kretzler, M.4
Schlöndorff, D.5
Anders, H.J.6
-
57
-
-
0037471003
-
Pyogenic bacterial infections in humans with IRAK-4 deficiency
-
Picard C, Puel A, Bonnet M, Ku CL, Bustamante J, Yang K, Soudais C, Dupuis S, Feinberg J, Fieschi C, Elbim C, Hitchcock R, Lammas D, Davies G, Al-Ghonaium A, Al-Rayes H, Al-Jumaah S, Al-Hajjar S, Al-Mohsen IZ, Frayha HH, Rucker R, Hawn TR, Aderem A, Tufenkeji H, Haraguchi S, Day NK, Good RA, Gougerot-Pocidalo MA, Ozinsky A, and Casanova JL. Pyogenic bacterial infections in humans with IRAK-4 deficiency. Science 299: 2076-2079, 2003.
-
(2003)
Science
, vol.299
, pp. 2076-2079
-
-
Picard, C.1
Puel, A.2
Bonnet, M.3
Ku, C.L.4
Bustamante, J.5
Yang, K.6
Soudais, C.7
Dupuis, S.8
Feinberg, J.9
Fieschi, C.10
Elbim, C.11
Hitchcock, R.12
Lammas, D.13
Davies, G.14
Al-Ghonaium, A.15
Al-Rayes, H.16
Al-Jumaah, S.17
Al-Hajjar, S.18
Al-Mohsen, I.Z.19
Frayha, H.H.20
Rucker, R.21
Hawn, T.R.22
Aderem, A.23
Tufenkeji, H.24
Haraguchi, S.25
Day, N.K.26
Good, R.A.27
Gougerot-Pocidalo, M.A.28
Ozinsky, A.29
Casanova, J.L.30
more..
-
58
-
-
0036193934
-
Staphylococcus aureus and Wegener's granulomatosis
-
Popa ER, Stegeman CA, Kallenberg CG, and Tervaert JW. Staphylococcus aureus and Wegener's granulomatosis. Arthritis Res 4: 77-79, 2002.
-
(2002)
Arthritis Res
, vol.4
, pp. 77-79
-
-
Popa, E.R.1
Stegeman, C.A.2
Kallenberg, C.G.3
Tervaert, J.W.4
-
59
-
-
16244376480
-
Toll-like receptors, endogenous ligands, and systemic autoimmune disease
-
Rifkin IR, Leadbetter EA, Busconi L, Viglianti G, and Marshak-Rothstein A. Toll-like receptors, endogenous ligands, and systemic autoimmune disease. Immunol Rev 204: 27-42, 2005.
-
(2005)
Immunol Rev
, vol.204
, pp. 27-42
-
-
Rifkin, I.R.1
Leadbetter, E.A.2
Busconi, L.3
Viglianti, G.4
Marshak-Rothstein, A.5
-
61
-
-
0344443213
-
Randomized, single-blind, placebo-controlled study of topical application of the immune response modulator resiquimod in healthy adults
-
Sauder DN, Smith MH, Senta-McMillian T, Soria I, and Meng TC. Randomized, single-blind, placebo-controlled study of topical application of the immune response modulator resiquimod in healthy adults. Antimicrob Agents Chemother 47: 3846-3852, 2003.
-
(2003)
Antimicrob Agents Chemother
, vol.47
, pp. 3846-3852
-
-
Sauder, D.N.1
Smith, M.H.2
Senta-McMillian, T.3
Soria, I.4
Meng, T.C.5
-
62
-
-
23744483354
-
TLR3 in antiviral immunity: Key player or bystander?
-
Schroder M and Bowie AG. TLR3 in antiviral immunity: key player or bystander? Trends Immunol 26: 462-468, 2005.
-
(2005)
Trends Immunol
, vol.26
, pp. 462-468
-
-
Schroder, M.1
Bowie, A.G.2
-
63
-
-
2942627626
-
Hydrophobicity: An ancient damage-associated molecular pattern that initiates innate immune responses
-
Seong SY and Matzinger P. Hydrophobicity: an ancient damage-associated molecular pattern that initiates innate immune responses. Nat Rev Immunol 4: 469-478, 2004.
-
(2004)
Nat Rev Immunol
, vol.4
, pp. 469-478
-
-
Seong, S.Y.1
Matzinger, P.2
-
64
-
-
0035876690
-
Viral infections and their impact on chronic renal allograft dysfunction
-
Soderberg-Naucler C and Emery VC. Viral infections and their impact on chronic renal allograft dysfunction. Transplantation 71: SS24-SS30, 2001.
-
(2001)
Transplantation
, vol.71
-
-
Soderberg-Naucler, C.1
Emery, V.C.2
-
65
-
-
0035879830
-
Application of a topical immune response modifier, resiquimod gel, to modify the recurrence rate of recurrent genital herpes: A pilot study
-
Spruance SL, Tyring SK, Smith MH, and Meng TC. Application of a topical immune response modifier, resiquimod gel, to modify the recurrence rate of recurrent genital herpes: a pilot study. J Infect Dis 184: 196-200, 2001.
-
(2001)
J Infect Dis
, vol.184
, pp. 196-200
-
-
Spruance, S.L.1
Tyring, S.K.2
Smith, M.H.3
Meng, T.C.4
-
66
-
-
0037378005
-
The molecular basis for the lack of immunostimulatory activity of vertebrate DNA
-
Stacey KJ, Young GR, Clark F, Sester DP, Roberts TL, Naik S, Sweet MJ, and Hume DA. The molecular basis for the lack of immunostimulatory activity of vertebrate DNA. J Immunol 170: 3614-3620, 2003.
-
(2003)
J Immunol
, vol.170
, pp. 3614-3620
-
-
Stacey, K.J.1
Young, G.R.2
Clark, F.3
Sester, D.P.4
Roberts, T.L.5
Naik, S.6
Sweet, M.J.7
Hume, D.A.8
-
67
-
-
0029946561
-
Trimethoprim-sulfamethoxazole (co-trimoxazole) for the prevention of relapses of Wegener's granulomatosis
-
Dutch Co-Trimoxazole Wegener Study Group
-
Stegeman CA, Tervaert JW, de Jong PE, and Kallenberg CG. Trimethoprim-sulfamethoxazole (co-trimoxazole) for the prevention of relapses of Wegener's granulomatosis. Dutch Co-Trimoxazole Wegener Study Group. N Engl J Med 335: 16-20, 1996.
-
(1996)
N Engl J Med
, vol.335
, pp. 16-20
-
-
Stegeman, C.A.1
Tervaert, J.W.2
De Jong, P.E.3
Kallenberg, C.G.4
-
68
-
-
1642566566
-
Nonmethylated CG motifs packaged into virus-like particles induce protective cytotoxic T cell responses in the absence of systemic side effects
-
Storni T, Ruedl C, Schwarz K, Schwendener RA, Renner WA, and Bachmann MF. Nonmethylated CG motifs packaged into virus-like particles induce protective cytotoxic T cell responses in the absence of systemic side effects. J Immunol 172: 1777-1785, 2004.
-
(2004)
J Immunol
, vol.172
, pp. 1777-1785
-
-
Storni, T.1
Ruedl, C.2
Schwarz, K.3
Schwendener, R.A.4
Renner, W.A.5
Bachmann, M.F.6
-
69
-
-
12144286763
-
Toll-like receptors 9 and 3 as essential components of innate immune defense against mouse cytomegalovirus infection
-
Tabeta K, Georgel P, Janssen E, Du X, Hoebe K, Crozat K, Mudd S, Shamel L, Sovath S, Goode J, Alexopoulou L, Flavell RA, and Beutler B. Toll-like receptors 9 and 3 as essential components of innate immune defense against mouse cytomegalovirus infection. Proc Natl Acad Sci USA 101: 3516-3521, 2004.
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 3516-3521
-
-
Tabeta, K.1
Georgel, P.2
Janssen, E.3
Du, X.4
Hoebe, K.5
Crozat, K.6
Mudd, S.7
Shamel, L.8
Sovath, S.9
Goode, J.10
Alexopoulou, L.11
Flavell, R.A.12
Beutler, B.13
-
70
-
-
4344703413
-
TH1 immune responses to fully MHC mismatched allografts are diminished in the absence of MyD88, a Toll-like receptor signal adaptor protein
-
Tesar BM, Zhang J, Li Q, and Goldstein DR. TH1 immune responses to fully MHC mismatched allografts are diminished in the absence of MyD88, a Toll-like receptor signal adaptor protein. Am J Transplant 4: 1429-1439, 2004.
-
(2004)
Am J Transplant
, vol.4
, pp. 1429-1439
-
-
Tesar, B.M.1
Zhang, J.2
Li, Q.3
Goldstein, D.R.4
-
71
-
-
15444380849
-
IFN-α enhances TLR3-mediated antiviral cytokine expression in human endothelial and epithelial cells by up-regulating TLR3 expression
-
Tissari J, Siren J, Meri S, Julkunen I, and Matikainen S. IFN-α enhances TLR3-mediated antiviral cytokine expression in human endothelial and epithelial cells by up-regulating TLR3 expression. J Immunol 174: 4289-4294, 2005.
-
(2005)
J Immunol
, vol.174
, pp. 4289-4294
-
-
Tissari, J.1
Siren, J.2
Meri, S.3
Julkunen, I.4
Matikainen, S.5
-
72
-
-
0037099425
-
Activation of the lipopolysaccharide signaling pathway in hepatic transplantation preservation injury
-
Tsoulfas G, Takahashi Y, Ganster RW, Yagnik G, Guo Z, Fung JJ, Murase N, and Geller DA. Activation of the lipopolysaccharide signaling pathway in hepatic transplantation preservation injury. Transplantation 74: 7-13, 2002.
-
(2002)
Transplantation
, vol.74
, pp. 7-13
-
-
Tsoulfas, G.1
Takahashi, Y.2
Ganster, R.W.3
Yagnik, G.4
Guo, Z.5
Fung, J.J.6
Murase, N.7
Geller, D.A.8
-
73
-
-
0037103247
-
Roles of toll-like receptors in C-C chemokine production by renal tubular epithelial cells
-
Tsuboi N, Yoshikai Y, Matsuo S, Kikuchi T, Iwami K, Nagai Y, Takeuchi O, Akira S, and Matsuguchi T. Roles of toll-like receptors in C-C chemokine production by renal tubular epithelial cells. J Immunol 169: 2026-2033, 2002.
-
(2002)
J Immunol
, vol.169
, pp. 2026-2033
-
-
Tsuboi, N.1
Yoshikai, Y.2
Matsuo, S.3
Kikuchi, T.4
Iwami, K.5
Nagai, Y.6
Takeuchi, O.7
Akira, S.8
Matsuguchi, T.9
-
74
-
-
3142779901
-
Therapeutics targeting the innate immune system
-
Ulevitch RJ. Therapeutics targeting the innate immune system. Nat Rev Immunol 4: 512-520, 2004.
-
(2004)
Nat Rev Immunol
, vol.4
, pp. 512-520
-
-
Ulevitch, R.J.1
-
75
-
-
2942679083
-
The immunobiology of the TLR9 subfamily
-
Wagner H. The immunobiology of the TLR9 subfamily. Trends Immunol 25: 381-386, 2003.
-
(2003)
Trends Immunol
, vol.25
, pp. 381-386
-
-
Wagner, H.1
-
76
-
-
0035252588
-
New trends in immunotherapy to prevent atopic diseases
-
Walker C and Zuany-Amorim C. New trends in immunotherapy to prevent atopic diseases. Trends Pharmacol Sci 22: 84-90, 2001.
-
(2001)
Trends Pharmacol Sci
, vol.22
, pp. 84-90
-
-
Walker, C.1
Zuany-Amorim, C.2
-
77
-
-
11144273976
-
Toll-like receptor 3 mediates West Nile virus entry into the brain causing lethal encephalitis
-
Wang T, Town T, Alexopoulou L, Anderson JF, Fikrig E, and Flavell RA. Toll-like receptor 3 mediates West Nile virus entry into the brain causing lethal encephalitis. Nat Med 10: 1366-1373, 2004.
-
(2004)
Nat Med
, vol.10
, pp. 1366-1373
-
-
Wang, T.1
Town, T.2
Alexopoulou, L.3
Anderson, J.F.4
Fikrig, E.5
Flavell, R.A.6
-
78
-
-
0035963518
-
Nephropathy and establishment of a renal reservoir of HIV type 1 during primary infection
-
Winston JA, Bruggeman LA, Ross MD, Jacobson J, Ross L, D'Agati VD, Klotman PE, and Klotman ME. Nephropathy and establishment of a renal reservoir of HIV type 1 during primary infection. N Engl J Med 344: 1979-1984, 2001.
-
(2001)
N Engl J Med
, vol.344
, pp. 1979-1984
-
-
Winston, J.A.1
Bruggeman, L.A.2
Ross, M.D.3
Jacobson, J.4
Ross, L.5
D'Agati, V.D.6
Klotman, P.E.7
Klotman, M.E.8
-
79
-
-
0036467357
-
In vivo expression of Toll-like receptor 2 and 4 by renal epithelial cells: IFN-γ and TNF-α mediated up-regulation during inflammation
-
Wolfs TG, Buurman WA, van Schadewijk A, de Vries B, Daemen MA, Hiemstra PS, and van't Veer C. In vivo expression of Toll-like receptor 2 and 4 by renal epithelial cells: IFN-γ and TNF-α mediated up-regulation during inflammation. J Immunol 168: 1286-1293, 2002.
-
(2002)
J Immunol
, vol.168
, pp. 1286-1293
-
-
Wolfs, T.G.1
Buurman, W.A.2
Van Schadewijk, A.3
De Vries, B.4
Daemen, M.A.5
Hiemstra, P.S.6
Van't Veer, C.7
-
80
-
-
33144487115
-
Novel role of Toll-like receptor-3 in hepatitis-associated membranoproliferative glomerulonephritis
-
Wörnle M, Schmidt H, Banas B, Merkle M, Henger A, Roeder M, Blattner S, Bock E, Kretzler M, Gröne HJ, and Schlöndorff D. Novel role of Toll-like receptor-3 in hepatitis-associated membranoproliferative glomerulonephritis. Am J Pathol 168: 370-385, 2006.
-
(2006)
Am J Pathol
, vol.168
, pp. 370-385
-
-
Wörnle, M.1
Schmidt, H.2
Banas, B.3
Merkle, M.4
Henger, A.5
Roeder, M.6
Blattner, S.7
Bock, E.8
Kretzler, M.9
Gröne, H.J.10
Schlöndorff, D.11
-
81
-
-
0043176281
-
Role of adaptor TRIF in the MyD88-independent toll-like receptor signaling pathway
-
Yamamoto M, Sato S, Hemmi H, Hoshino K, Kaisho T, Sanjo H, Takeuchi O, Sugiyama M, Okabe M, Takeda K, and Akira S. Role of adaptor TRIF in the MyD88-independent toll-like receptor signaling pathway. Science 301: 640-643, 2003.
-
(2003)
Science
, vol.301
, pp. 640-643
-
-
Yamamoto, M.1
Sato, S.2
Hemmi, H.3
Hoshino, K.4
Kaisho, T.5
Sanjo, H.6
Takeuchi, O.7
Sugiyama, M.8
Okabe, M.9
Takeda, K.10
Akira, S.11
-
82
-
-
0037114185
-
Cutting edge: A novel Toll/IL-1 receptor domain-containing adapter that preferentially activates the IFN-β promoter in the Toll-like receptor signaling
-
Yamamoto M, Sato S, Mori K, Hoshino K, Takeuchi O, Takeda K, and Akira S. Cutting edge: a novel Toll/IL-1 receptor domain-containing adapter that preferentially activates the IFN-β promoter in the Toll-like receptor signaling. J Immunol 169: 6668-6672, 2002.
-
(2002)
J Immunol
, vol.169
, pp. 6668-6672
-
-
Yamamoto, M.1
Sato, S.2
Mori, K.3
Hoshino, K.4
Takeuchi, O.5
Takeda, K.6
Akira, S.7
-
83
-
-
3242813113
-
The RNA helicase RIG-I has an essential function in double-stranded RNA-induced innate antiviral responses
-
Yoneyama M, Kikuchi M, Natsukawa T, Shinobu N, Imaizumi T, Miyagishi M, Taira K, Akira S, and Fujita T. The RNA helicase RIG-I has an essential function in double-stranded RNA-induced innate antiviral responses. Nat Immunol 5: 730-737, 2004.
-
(2004)
Nat Immunol
, vol.5
, pp. 730-737
-
-
Yoneyama, M.1
Kikuchi, M.2
Natsukawa, T.3
Shinobu, N.4
Imaizumi, T.5
Miyagishi, M.6
Taira, K.7
Akira, S.8
Fujita, T.9
|