Variable expression of Toll-like receptor in murine innate and adaptive immune cell lines

International Immunology

Volumn 14, Issue 9, 2002, Pages 1065-1074

  Applequist, Steven E ^a   Wallin, Robert P A ^a   Ljunggren, Hans Gustaf ^a,b  

^a KAROLINSKA INSTITUTE   (Sweden)

^b KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

Author keywords

Cellular activation; Inflammation; Innate immunity; Mouse

Indexed keywords

PROLINE; TOLL LIKE RECEPTOR;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL ACTIVATION; CELL LINE; CONTROLLED STUDY; GENE EXPRESSION; HUMAN; IMMUNE RESPONSE; IMMUNE SYSTEM; IMMUNOCOMPETENT CELL; MAST CELL; MICROGLIA; MOLECULAR CLONING; MOUSE; NEUTROPHIL; NONHUMAN; NUCLEOTIDE SEQUENCE; PATTERN RECOGNITION; PREDICTION; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; SEQUENCE HOMOLOGY;

EID: 0036735155     PISSN: 09538178     EISSN: None     Source Type: Journal    
DOI: 10.1093/intimm/dxf069     Document Type: Article

References (96)

1. Innate immune recognition: Mechanisms and pathways
2. A human homologue of the Drosophila Toll protein signals activation of adaptive immunity
3. A family of human receptors structurally related to Drosophila Toll
4. Toll-like receptors: Molecular mechanisms of the mammalian immune response
5. The innate immune response to bacterial flagellin is mediated by Toll-like receptor 5
6. Dendritic-cell function in Toll-like receptor- and MyD88-knockout mice
7. Toll meets bacterial CpG-DNA
8. OmpA targets dendritic cells, induces their maturation and delivers antigen into the MHC class I presentation pathway
9. Toll-like receptor 4, but not toll-like receptor 2, is a signaling receptor for Escherichia and Salmonella lipopolysaccharides
10. Differential expression and regulation of macrophage inflammatory protein (MIP)-1alpha and MIP-2 genes by alveolar and peritoneal macrophages in LPS-hyporesponsive C3H/HeJ mice
11. Evidence for an accessory protein function for Toll-like receptor 1 in anti-bacterial responses
12. Cooperation of Toll-like receptor 2 and 6 for cellular activation by soluble tuberculosis factor and Borrelia burgdorferi outer surface protein A lipoprotein: Role of Toll-interacting protein and IL-1 receptor Toll-like receptor 2 signaling
13. Escherichia coli P fimbriae utilize the Toll-like receptor 4 pfathway for cell activation
14. CD1lb/CD18 acts in concert with CD14 and Toll-like receptor (TLR) 4to elicit full lipopolysaccharide and taxol-inducible gene expression
15. Host defense mechanisms triggered by microbial lipoproteins through toll-like receptors
16. Differential roles of TLR2 and TLR4 in recognition of Gram-negative and Gram-positive bacterial cell wall components
17. The Toll-like receptor 2 is recruited to macrophage phagosomes and discriminates between pathogens
18. Toll-like receptor 4-deficient mice have reduced bone destruction following mixed anaerobic infection
19. A Toll-like receptor recognizes bacterial DNA
20. Toll-like receptors confer responsiveness to lipopolysaccharide from Porphyromonas gingivalis in human gingival fibroblasts
21. Activation of Toll-like receptor-2 by glycosylphosphatidylinositol anchors from a protozoan parasite
22. The extra domain A of fibronectin activates Toll-like receptor 4
23. Lipopolysaccharide-induced IL-18 secretion from murine Kupffer cells independently of myeloid differentiation factor 88 that is critically involved in induction of production of IL-12 and IL-1beta
24. IL-9 and IL-13 production by activated mast cells is strongly enhanced in the presence of lipopolysaccharide: NF-kappa B is decisively involved in the expression of IL-9
25. Discrimination of bacterial lipoproteins by Toll-like receptor 6
26. Protective roles of mast cells against enterobacterial infection are mediated by toll-like receptor 4
27. Cutting edge: Toll-like receptor 4 (TLR4)-deficient mice are hyporesponsive to lipopolysaccharide: Evidence for TLR4 as the Lps gene product
28. Microbial lipopeptides stimulate dendritic cell maturation via Toll-like receptor 2
29. The role of toll-like receptors (TLR) in bacteria-induced maturation of murine dendritic cells (DCS). Peptidoglycan and lipoteichoic acid are inducers of DC maturation and require TLR2
30. Cellular responses to bacterial cell wall components are mediated through MyD88-dependent signaling cascades
31. Cutting edge: Heat shock protein 60 is a putative endogenous ligand of the toll-like receptor-4 complex
32. In vivo expression of proinflammatory mediators in the adult heart after endotoxin administration: The role of toll-like receptor-4
33. Different Toll-like receptor agonists induce distinct macrophage responses
34. Effects of 15-deoxy-delta(12,14) prostaglandin J(2) and interleukin-4 in Toll-like receptor-4-mutant glial cells
35. Involvement of lipopolysaccharicle binding protein, CD14, and Toll-like receptors in the initiation of innate immune responses by Treponema glycolipids
36. Induction of direct antimicrobial activity through mammalian toll-like receptors
37. Induction of TNF-alpha and MnSOD by endotoxin: Role of membrane CD14 and Toll-like receptor-4
38. The repertoire for pattern recognition of pathogens by the innate immune system is defined by cooperation between toll-like receptors
39. Cutting edge: Functional interactions between toll-like recepftor (TLR) 2 and TLR1 or TLR6 in response to phenol-soluble modulin
40. Unresponsiveness of MyD88-deficient mice to endotoxin
41. Gapped BLAST and PSI-BLAST: A new generation of protein database search programs
42. The IMAGE Consortium: An integrated molecular analysis of genomes and their expression
43. CD14-dependent and independent pathways in lipopolysaccharide-incluced activation of a murine B-cell line, CH12 LX
44. Genetic structure and chromosomal mapping of MyD88
45. Establishment of a cell line with features of early dendritic cell precursors from fetal mouse skin
46. Immortalized dendritic cell line fully competent in antigen presentation initiates primary T cell responses in vivo
47. Modulation of cytokine expression in mouse dendritic cell clones
48. Functional macrophage cell lines transformed by Abelson leukemia virus
49. Reticulum cell sarcoma: An effector cell in antibody-dependent cell-mediated immunity
50. Phagocytosis and cytolysis by a macrophage tumour and its cloned cell line
51. Biologic and biochemical activities of continuous macrophage cell lines P388D1 and J774.1
52. Glomerular epithelial, mesangial, and endothelial cell lines from transgenic mice
53. Immortalization of murine microglial cells by a v-raf/v-myc carrying retrovirus
54. Immortalization of mouse bone marrow-derived mast cells with Ad12-SV40 virus
55. Stem cell factor induces mast cell adhesion to fibronectin
56. Production of interleukin 3 and gamma-interferon by an antigen-specific mouse suppressor T cell clone
57. Cell cycle related heterogeneity of la antigen expression on a murine B lymphoma cell line: Analysis by flow cytometry
58. Murine B cell leukemia line with inducible surface immunoglobulin expression
59. Variability in the lambda light chain sequences of mouse antibody
60. Mouse myelomas producing precipitating antibody to nucleic acid bases and/or nitrophenyl derivatives
61. Host resistance directed selectively against H-2-deficient lymphoma variants. Analysis of the mechanism
62. Immunologic characteristics in relation to high and low leukemogenic activity of radiation leukemia virus variants. I. Cellular analysis of immunosuppression
63. Long term culture of tumour-specific cytotoxic T cells
64. Demonstration of permanent factor-dependent multipotential (erythroid/neutrophil/basophil) hematopoietic progenitor cell lines
65. Cytokine-dependent granulocytic differentiation. Regulation of proliferative and differentiative responses in a murine progenitor cell line
66. Generation of large numbers of dendritic cells from mouse bone marrow cultures supplemented with granulocyte/macrophage colony-stimulating factor
67. Cloning and characterization of the murine toll-like receptor 5 (TIr5) gene: Sequence and mRNA expression studies in Salmonella-susceptible MOLF/Ei mice
68. Three novel mammalian toll-like receptors: Gene structure, expression, and evolution
69. Toll-like receptor-2 mediates mycobacteria-induced proinflammatory signaling in macrophages
70. Cutting edge: Repurification of lipopolysaccharide eliminates signaling through both human and murine toll-like receptor 2
71. Endotoxin-tolerant mice have mutations in Toll-like receptor 4 (TIr4)
72. Structural basis for signal transcluction by the Toll/interleukin-1 receptor domains
73. TIRAP: An adapter molecule in the Toll signaling pathway
74. Recognition of double-stranded RNA and activation of NF-kappaB by Toll- like receptor 3
75. Regulation of Toll-like receptors in human monocytes and dendritic cells
76. Differential expression and regulation of toll-like receptors (TLR) in human leukocytes: Selective expression of TLR3 in dendritic cells
77. Activation of toll-like receptor 2 on human dendritic cells triggers induction of IL-12, but not IL-10
78. Immunobiology of dendritic cells
79. Mast cell modulation of neutrophil influx and bacterial clearance at sites of infection through TNF-alpha
80. Critical protective role of mast cells in a model of acute septic peritonitis
81. Non-IgE-dependent bacteria-induced histamine release from human lung and tonsillar mast cells
82. Mast cells in infection and immunity
83. IL-6 production by rat peritoneal mast cells is not necessarily preceded by histamine release and can be induced by bacterial lipopolysaccharide
84. Neutrophils, host defense, and inflammation: A doubled-edged sword
85. The neutrophil as a cellular source of chemokines
86. Lipopolysaccharides prime whole and human blood and isolated neutrophils for the increased synthesis of 5-lipoxygenase products by enhancing arachidonic acid availability: Involvement of the CD14 antigen
87. Priming of neutrophils by lipopolysaccharide for enhanced release of superoxide. Requirement for plasma but not for tumor necrosis factor-alpha
88. Growth of the B lymphoma cell line WEHI-231 by anti-immunoglobulin, lipopolysaccharide, and other bacterial products
89. CpG motifs in bacterial DNA trigger direct B-cell activation
90. The role of cell surface receptors in the activation of human B cells by phosphorothioate oligonucleotides
91. Cutting edge: Human B cell function is regulated by interaction with soluble CD14: Opposite effects on IgG1 and IgE production
92. A CD14-independent LPS receptor cluster
93. Stimulation of B-lymphocytes by endotoxin. Reactions of thymus-deprived mice and karyotopic analysis of dividing cells in mice bearing T 6 T 6 thymus grafts
94. Selective induction of DNA synthesis in T and B lymphocytes
95. Gene expression of Toll-like receptor 2, but not Toll-like receptor 4, is induced by LPS and inflammatory cytokines in mouse macrophages
96. Expression of toll-like receptor 2 on gamma delta T cells bearing invariant V gamma 6/V delta 1 induced by Escherichia coli infection in mice