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Volumn 83, Issue 3, 1996, Pages 295-303

Plasmodium falciparum: Amplification and overexpression of pfmdr1 is not necessary for increase mefloquine resistance

Author keywords

[No Author keywords available]

Indexed keywords

CHLOROQUINE; HALOFANTRINE; MEFLOQUINE; QUININE;

EID: 0030219812     PISSN: 00144894     EISSN: None     Source Type: Journal    
DOI: 10.1006/expr.1996.0077     Document Type: Article
Times cited : (40)

References (37)
  • 1
    • 0026645269 scopus 로고
    • Selection for high-level chloroquine resistance results in deamplification of the pfmdr1 gene and increased sensitivity to mefloquine in Plasmodium falciparum
    • BARNES, D. A., FOOTE, S. J., GALATIS, D., KEMP, D. J., AND COWMAN, A. F. 1992. Selection for high-level chloroquine resistance results in deamplification of the pfmdr1 gene and increased sensitivity to mefloquine in Plasmodium falciparum. European Molecular Biology Organisation Journal 11, 3067-3075.
    • (1992) European Molecular Biology Organisation Journal , vol.11 , pp. 3067-3075
    • Barnes, D.A.1    Foote, S.J.2    Galatis, D.3    Kemp, D.J.4    Cowman, A.F.5
  • 2
    • 0024523842 scopus 로고
    • Subtelomeric chromosome deletions in field isolates of Plasmodium falciparum and their relationship to loss of cytoadherence in vitro
    • BIGGS, B. A., KEMP, D. J., AND BROWN, G. V. 1989. Subtelomeric chromosome deletions in field isolates of Plasmodium falciparum and their relationship to loss of cytoadherence in vitro. Proceedings of the National Academy of Sciences of the USA 86, 2428-2432.
    • (1989) Proceedings of the National Academy of Sciences of the USA , vol.86 , pp. 2428-2432
    • Biggs, B.A.1    Kemp, D.J.2    Brown, G.V.3
  • 3
    • 0020415381 scopus 로고
    • Type II mefloquine resistance in Thailand
    • BOUDREAU, E. F., WEBSTER, H. K., PAVANAND, K., AND THOSINGHA, L. 1982. Type II mefloquine resistance in Thailand [Letter]. Lancet 2(8311), 1335.
    • (1982) Lancet , vol.2 , Issue.8311 , pp. 1335
    • Boudreau, E.F.1    Webster, H.K.2    Pavanand, K.3    Thosingha, L.4
  • 4
    • 0028014644 scopus 로고
    • Selection for mefloquine resistance in Plasmodium falciparum is linked to amplification of the pfmdr1 gene and cross-resistance to halofantrine and quinine
    • COWMAN, A. F., GALATIS, D., AND THOMPSON, J. K. 1994. Selection for mefloquine resistance in Plasmodium falciparum is linked to amplification of the pfmdr1 gene and cross-resistance to halofantrine and quinine. Proceedings of the National Academy of Sciences of the USA 91, 1143-1147.
    • (1994) Proceedings of the National Academy of Sciences of the USA , vol.91 , pp. 1143-1147
    • Cowman, A.F.1    Galatis, D.2    Thompson, J.K.3
  • 5
    • 0025786518 scopus 로고
    • A P-glycoprotein homologue of Plasmodium falciparum is localized on the digestive vacuole
    • COWMAN, A. F., KARCZ, S., GALATIS, D., AND CULVENOR, J. G. 1991. A P-glycoprotein homologue of Plasmodium falciparum is localized on the digestive vacuole. Journal of Cell Biology 113, 1033-1042.
    • (1991) Journal of Cell Biology , vol.113 , pp. 1033-1042
    • Cowman, A.F.1    Karcz, S.2    Galatis, D.3    Culvenor, J.G.4
  • 7
    • 0021381028 scopus 로고
    • A technique for radiolabelling DNA restriction endonuclease fragments to high specific activity
    • FEINBERG, A. P., AND VOGELSTEIN, B. 1984. A technique for radiolabelling DNA restriction endonuclease fragments to high specific activity. Analytical Biochemistry 137, 266-267.
    • (1984) Analytical Biochemistry , vol.137 , pp. 266-267
    • Feinberg, A.P.1    Vogelstein, B.2
  • 9
    • 0025269612 scopus 로고
    • Several alleles of the multidrug-resistance gene are closely linked to chloroquine resistance in Plasmodium falciparum
    • FOOTE, S. J., KYLE, D. E., MARTIN, R. K., ODUOLA, A. M., FORSYTH, K., KEMP, D. J., AND COWMAN, A. F. 1990. Several alleles of the multidrug-resistance gene are closely linked to chloroquine resistance in Plasmodium falciparum. Nature 345, 255-258.
    • (1990) Nature , vol.345 , pp. 255-258
    • Foote, S.J.1    Kyle, D.E.2    Martin, R.K.3    Oduola, A.M.4    Forsyth, K.5    Kemp, D.J.6    Cowman, A.F.7
  • 10
    • 0024338609 scopus 로고
    • Amplification of the multidrug resistance gene in some chloroquine-resistant isolates of P. falciparum
    • FOOTE, S. J., THOMPSON, J. K., COWMAN, A. F., AND KEMP, D. J. 1989. Amplification of the multidrug resistance gene in some chloroquine-resistant isolates of P. falciparum. Cell 57, 921-930.
    • (1989) Cell , vol.57 , pp. 921-930
    • Foote, S.J.1    Thompson, J.K.2    Cowman, A.F.3    Kemp, D.J.4
  • 11
    • 0020576779 scopus 로고
    • A phase II clinical trial of mefloquine in patients with chloroquine-resistant falciparum malaria in Thailand
    • HARINASUTA, T., BUNNAG, D., AND WERNSDORFER, W. H. 1983. A phase II clinical trial of mefloquine in patients with chloroquine-resistant falciparum malaria in Thailand. Bulletin of WHO 61(2), 299-305.
    • (1983) Bulletin of WHO , vol.61 , Issue.2 , pp. 299-305
    • Harinasuta, T.1    Bunnag, D.2    Wernsdorfer, W.H.3
  • 12
    • 0027732045 scopus 로고
    • Phosphorylation of a P-glycoprotein homologue in Plasmodium falciparum
    • LIM, A. S. Y., AND COWMAN, A. F. 1993. Phosphorylation of a P-glycoprotein homologue in Plasmodium falciparum. Molecular and Biochemical Parasitology 62, 293-302.
    • (1993) Molecular and Biochemical Parasitology , vol.62 , pp. 293-302
    • Lim, A.S.Y.1    Cowman, A.F.2
  • 13
    • 0030217936 scopus 로고    scopus 로고
    • Plasmodium falciparum: Chloroquine selection of a cloned line and DNA rearrangements
    • in press
    • LIM, A. S. Y., AND COWMAN, A. F. 1996. Plasmodium falciparum: Chloroquine selection of a cloned line and DNA rearrangements. Experimental Parasitology 83, in press.
    • (1996) Experimental Parasitology , vol.83
    • Lim, A.S.Y.1    Cowman, A.F.2
  • 15
    • 0023137728 scopus 로고
    • Reversal of chloroquine resistance in Plasmodium falciparum by verapamil
    • MARTIN, S. K., ODUOLA, A. M., AND MILHOUS, W. K. 1987. Reversal of chloroquine resistance in Plasmodium falciparum by verapamil. Science 235, 899-901.
    • (1987) Science , vol.235 , pp. 899-901
    • Martin, S.K.1    Oduola, A.M.2    Milhous, W.K.3
  • 17
    • 0023581974 scopus 로고
    • Malaria on the Thai-Burmese border: Treatment of 5192 patients with mefloquine-sulfadoxine-pyrimethamine
    • NOSTEN, F., IMVITHAYA, S., VINCENTI, M., DELMAS, G., LEBIHAN, G., HAUSLER, B., AND WHITE, N. 1987. Malaria on the Thai-Burmese border: Treatment of 5192 patients with mefloquine-sulfadoxine-pyrimethamine. Bulletin of WHO 65, 891-896.
    • (1987) Bulletin of WHO , vol.65 , pp. 891-896
    • Nosten, F.1    Imvithaya, S.2    Vincenti, M.3    Delmas, G.4    Lebihan, G.5    Hausler, B.6    White, N.7
  • 19
    • 0028135205 scopus 로고
    • A strong association between mefloquine and halofantrine resistance and amplification, overexpression, and mutation in the P-glycoprotein gene homolog (pfmdr) of Plasmodium falciparum in vitro
    • PEEL, S. A., BRIGHT, P., YOUNT, B., HANDY, J., AND BARIC, R. S. 1994. A strong association between mefloquine and halofantrine resistance and amplification, overexpression, and mutation in the P-glycoprotein gene homolog (pfmdr) of Plasmodium falciparum in vitro. American Journal of Tropical Medicine and Hygiene 51, 648-658.
    • (1994) American Journal of Tropical Medicine and Hygiene , vol.51 , pp. 648-658
    • Peel, S.A.1    Bright, P.2    Yount, B.3    Handy, J.4    Baric, R.S.5
  • 21
    • 0022432484 scopus 로고
    • Rapid transfer of DNA from agarose to nylon membrane
    • REED, K. C., AND MANN, D. A. 1985. Rapid transfer of DNA from agarose to nylon membrane. Nucleic Acids Research 13, 7207-7221.
    • (1985) Nucleic Acids Research , vol.13 , pp. 7207-7221
    • Reed, K.C.1    Mann, D.A.2
  • 22
    • 0026081676 scopus 로고
    • The structure of the calmodulin gene of Plasmodium falciparum
    • ROBSON, K., AND JENNINGS, M. W. 1991. The structure of the calmodulin gene of Plasmodium falciparum. Molecular and Biochemical Parasitology 46, 19-34.
    • (1991) Molecular and Biochemical Parasitology , vol.46 , pp. 19-34
    • Robson, K.1    Jennings, M.W.2
  • 23
    • 0019402859 scopus 로고
    • Cloning of naturally occurring mixed infections of malaria parasites
    • ROSARIO, V. E. 1981. Cloning of naturally occurring mixed infections of malaria parasites. Science 212, 1037-1038.
    • (1981) Science , vol.212 , pp. 1037-1038
    • Rosario, V.E.1
  • 25
    • 0017810066 scopus 로고
    • Antimalarial activities of various 4-quinoline-methanols with special attention to WR-142,490 (mefloquine)
    • SCHMIDT, L. H., CROSBY, R., RASCO, J., AND VAUGHAN, D. 1978. Antimalarial activities of various 4-quinoline-methanols with special attention to WR-142,490 (mefloquine). Antimicrobial Agents and Chemotherapy 13, 1011-1030.
    • (1978) Antimicrobial Agents and Chemotherapy , vol.13 , pp. 1011-1030
    • Schmidt, L.H.1    Crosby, R.2    Rasco, J.3    Vaughan, D.4
  • 26
    • 0021153574 scopus 로고
    • Separation of yeast chromosome-sized DNAs by pulsed field gradient gel electrophoresis
    • SCHWARTZ, D. C., AND CANTOR, C. R. 1984. Separation of yeast chromosome-sized DNAs by pulsed field gradient gel electrophoresis. Cell 37, 67-75.
    • (1984) Cell , vol.37 , pp. 67-75
    • Schwartz, D.C.1    Cantor, C.R.2
  • 27
    • 0023504973 scopus 로고
    • Purification, specific fragmentation and separation of large DNA molecules
    • SMITH, C. L., AND CANTOR, C. R. 1987. Purification, specific fragmentation and separation of large DNA molecules. Methods in Enzymology 155, 449.
    • (1987) Methods in Enzymology , vol.155 , pp. 449
    • Smith, C.L.1    Cantor, C.R.2
  • 28
    • 0017311840 scopus 로고
    • Human malaria parasites in continuous culture
    • TRAGER, W., AND JENSEN, J. 1976. Human malaria parasites in continuous culture. Science 193, 673-675.
    • (1976) Science , vol.193 , pp. 673-675
    • Trager, W.1    Jensen, J.2
  • 29
    • 0028274565 scopus 로고
    • Expression of the Plasmodial pfmdr 1 gene in mammalian cells is associated with increased susceptibility to chloroquine
    • VAN ES, H. H. G., KARCZ, S., CHU, F., COWMAN, A. F., VIDAL, S., GROS, P., AND SCHURR, E. 1994a. Expression of the Plasmodial pfmdr 1 gene in mammalian cells is associated with increased susceptibility to chloroquine. Molecular and Cellular Biology 14, 2419-2428.
    • (1994) Molecular and Cellular Biology , vol.14 , pp. 2419-2428
    • Van Es, H.H.G.1    Karcz, S.2    Chu, F.3    Cowman, A.F.4    Vidal, S.5    Gros, P.6    Schurr, E.7
  • 30
    • 0028607543 scopus 로고
    • Enhanced lysosomal acidification leads to increased chloroquine accumulation in CHO cells expressing the pfmdr 1 gene
    • VAN ES, H. H. G., RENKEMA, H., AERTS, H., AND SCHURR, E. 1994b. Enhanced lysosomal acidification leads to increased chloroquine accumulation in CHO cells expressing the pfmdr 1 gene. Molecular and Biochemical Parasitology 68, 209-219.
    • (1994) Molecular and Biochemical Parasitology , vol.68 , pp. 209-219
    • Van Es, H.H.G.1    Renkema, H.2    Aerts, H.3    Schurr, E.4
  • 31
    • 0029047328 scopus 로고
    • Functional complementation of the ste6 gene of Saccharomyces cerevisiae with the pfmdr1 gene of Plasmodium falciparum
    • VOLKMAN, S. K., COWMAN, A. F., AND WIRTH, D. F. 1995. Functional complementation of the ste6 gene of Saccharomyces cerevisiae with the pfmdr1 gene of Plasmodium falciparum. Proceedings of the National Academy of Sciences of the USA 92, 8921-8925.
    • (1995) Proceedings of the National Academy of Sciences of the USA , vol.92 , pp. 8921-8925
    • Volkman, S.K.1    Cowman, A.F.2    Wirth, D.F.3
  • 35
    • 0003948705 scopus 로고
    • Technical Report Series No. 711, World Health Organisation, Geneva
    • WHO 1984. Advances in Malaria Chemotherapy, Technical Report Series No. 711, World Health Organisation, Geneva.
    • (1984) Advances in Malaria Chemotherapy
  • 36
    • 0024356582 scopus 로고
    • Amplification of a gene related to mammalian mdr genes in drug-resistant Plasmodium falciparum
    • WILSON, C. M., SERRANO, A. E., WASLEY, A., BOGENSCHUTZ, M. P., SHANKAR, A. H., AND WIRTH, D. F. 1989. Amplification of a gene related to mammalian mdr genes in drug-resistant Plasmodium falciparum. Science 244, 1184-1186.
    • (1989) Science , vol.244 , pp. 1184-1186
    • Wilson, C.M.1    Serrano, A.E.2    Wasley, A.3    Bogenschutz, M.P.4    Shankar, A.H.5    Wirth, D.F.6


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