Androgens, aging, and Alzheimer's disease

Endocrine

Volumn 29, Issue 2, 2006, Pages 233-241

  Pike, Christian J ^a   Rosario, Emily R ^a   Nguyen, Thuy Vi V ^a  

^a UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

Author keywords

Alzheimer's disease; Dihydrotestosterone; Luteinizing hormone; Neuroprotection; Testosterone; amyloid

Indexed keywords

AMYLOID BETA PROTEIN; ANDROGEN; GONADOTROPIN; TESTOSTERONE;

AGING; ALZHEIMER DISEASE; CELL VIABILITY; HORMONE ACTION; HUMAN; NEUROPROTECTION; PATHOGENESIS; PRIORITY JOURNAL; REGULATORY MECHANISM; REVIEW; RISK FACTOR;

EID: 33746191815     PISSN: 1355008X     EISSN: 15590100     Source Type: Journal    
DOI: 10.1385/ENDO:29:2:233     Document Type: Review

References (165)

1. Paganini-Hill, A. and Henderson, V. W. (1994). Am. J. Epidemiol. 140, 256-261.
2. Henderson, V. W., Paganini-Hill, A., Emanuel, C. K., Dunn, M. E., and Buckwalter, J. G. (1994). Arch. Neurol. 51, 896-900.
3. Henderson, V. W. (1997). Neurology 48, S27-35.
4. Cholerton, B., Gleason, C. E., Baker, L. D., and Asthana, S. (2002). Drugs Aging 19, 405-427.
5. Feldman, H. A., Longcope, C., Derby, C. A., et al. (2002). J. Clin. Endocrinol. Metab. 87, 589-598.
6. Gray, A., Feldman, H. A., McKinlay, J. B., and Longcope, C. (1991). J. Clin. Endocrinol. Metab. 73, 1016-1025.
7. Muller, M., den Tonkelaar, I., Thijssen, J. H., Grobbee, D. E., and van der Schouw, Y. T. (2003). Eur. J. Endocrinol. 149, 583-589.
8. Purifoy, F. E., Koopmans, L. H., and Mayes, D. M. (1981). Hum. Biol. 53, 499-511.
9. Vermeulen, A., Kaufman, J. M., and Giagulli, V. A. (1996). J. Clin. Endocrinol. Metab. 81, 1821-1826.
10. Harman, S. M., Metter, E. J., Tobin, J. D., Pearson, J., and Blackman, M. R. (2001). J. Clin. Endocrinol. Metab. 86, 724-731.
11. Nankin, H. R. and Calkins, J. H. (1986). J. Clin. Endocrinol. Metab. 63, 1418-1420.
12. Lewis, J. G., Ghanadian, R., and Chisholm, G. D. (1976). Acta Endocrinol. (Copenh.) 82, 444-448.
13. Pirke, K. M. and Doerr, P. (1973). Acta Endocrinol. (Copenh.) 74, 792-800.
14. Pirke, K. M. and Doerr, P. (1975). Acta Endocrinol. (Copenh.) 79, 357-365.
15. Pirke, K. M. and Doerr, P. (1975). Acta Endocrinol. (Copenh.) 80, 171-178.
16. Stearns, E. L., MacDonnell, J. A., Kaufman, B. J., et al. (1974). Am. J. Med. 57, 761-766.
17. Vermeulen, A., Kaufman, J. M., and Giasulli, V. A. (1996). J. Clin Endocrinol. Metab. 81, 1821-1826.
18. Vermeulen, A., Rubens, R., and Verdonck, L. (1972). J. Clin. Endocrinol. Metab. 34, 730-735.
19. Baker, H. W., Burger, H. G., de Kretser, D. M., et al. (1976). Clin. Endocrinol. 5, 349-372.
20. Davidson, J. M., Chen, J. J., Crapo, L., Gray, G. D., Greenleaf, W. J., and Catania, J. A. (1983). J. Clin. Endocrinol. Metab. 57, 71-77.
21. Morley, J. E., Kaiser, F. E., Perry, H. M., et al. (1997). Metabolism 46, 410-413.
22. Zmuda, J. M., Cauley, J. A., Kriska, A., Glynn, N. W., Gutai, J. P., and Kuller, L. H. (1997). Am. J. Epidemiol. 146, 609-617.
23. Rosario, E. R., Chang, L., Stanczyk, F. Z., and Pike, C. J. (2004). JAMA 292, 1431-1432.
24. Swerdloff, R. S. and Wang, C. (2004). Best Pract. Res. Clin. Endocrinol. Metab. 18, 349-362.
25. Morley, J. E. (2001). Maturitas 38, 61-71; discussion 71-63.
26. Korenman, S. G., Morley, J. E., Mooradian, A. D., et al. (1990). J. Clin. Endocrinol. Metab. 71, 963-969.
27. Kaufman, J. M. and Vermeulen, A. (2005). Endocr. Rev. 26, 833-876.
28. Baumgartner, R. N., Waters, D. L., Gallagher, D., Morley, J. E., and Garry, P. J. (1999). Mech. Ageing Dev. 107, 123-136.
29. Sheffield-Moore, M. and Urban, R. J. (2004). Trends Endocrinol. Metab. 15, 110-115.
30. Reed, R. L., Pearlmutter, L., Yochum, K., Meredith, K. E., and Mooradian, A. D. (1991). J. Am. Geriatr. Soc. 39, 555-561.
31. Frontera, W. R., Hughes, V. A., Fielding, R. A., Fiatarone, M. A., Evans, W. J., and Roubenoff, R. (2000). J. Appl. Physiol. 88, 1321-1326.
32. Bhasin, S., Woodhouse, L., and Storer, T. W. (2001). J. Endocrinol. 170, 27-38.
33. Burger, H., de Laet, C. E., van Daele, P. L., et al. (1998). Am. J. Epidemiol. 147, 871-879.
34. Jones, G., Nguyen, T., Sambrook, P., Kelly, P. J., and Eisman, J. A. (1994). BMJ 309, 691-695.
35. Orwoll, E. S. and Klein, R. F. (1995). Endocr. Rev. 16, 87-116.
36. Gooren, L. (2003). J. Steroid Biochem. Mol. Biol. 85, 349-355.
37. Bowen, R. L., Isley, J. P., and Atkinson, R. L. (2000). J. Neuroendocrinol. 12, 351-354.
38. Breuer, B., Trungold, S., Martucci, C., et al. (2001). Maturitas 39, 147-159.
39. Abbasi, A., Mattson, D. E., Cuisinier, M., et al. (1994). Arch. Phys. Med. Rehabil. 75, 594-599.
40. Thomas, J. L., Quang, B. T., Ochsenbein, E., and Vincent, J. P. (2003). J. Nutr. Health Aging 7, 437-439.
41. Abbasi, A. A., Drinka, P. J., Mattson, D. E., and Rudman, D. (1993). J. Am. Geriatr. Soc. 41, 975-982.
42. Hogervorst, E., Williams, J., Budge, M., Barnetson, L., Combrinck, M., and Smith, A. D. (2001). Neuro. Endocrinol. Lett. 22, 163-168.
43. Hogervorst, E., Combrinck, M., and Smith, A. D. (2003). Neuro. Endocrinol. Lett. 24, 203-208.
44. Hogervorst, E., Lehmann, D. J., Warden, D. R., McBroom, J., and Smith, A. D. (2002). Int. J. Geriatr. Psychiatry 17, 938-940.
45. Lehmann, D. J., Hogervorst, E., Warden, D. R., Smith, A. D., Butler, H. T., and Ragoussis, J. (2004). J. Neurol. Neurosurg. Psychiatry 75, 163-164.
46. Hogervorst, E., Bandelow, S., Combrinck, M., and Smith, A. D. (2004). Exp. Gerontol. 39, 1633-1639.
47. Watanabe, T., Koba, S., Kawamura, M., et al. (2004). Metabolism 53, 476-482.
48. Paoletti, A. M., Congia, S., Lello, S., et al. (2004). Neurology 62, 301-303.
49. Rasmuson, S., Nasman, B., Carlstrom, K., and Olsson, T. (2002). Dement. Geriatr. Cogn. Disord. 13, 74-79.
50. Almeida, O. P., Riono, A., Clarnette, R., and Martins, R. N. (2000). Alzheimer's Rep. 3, 15-18.
51. Pennanen, C., Laakso, M. P., Kivipelto, M., Ramberg, J., and Soininen, H. (2004). J. Neuroendocrinol. 16, 95-98.
52. Militello, A., Vitello, G., Lunetta, C., et al. (2002). J. Neurol. Sci. 195, 67-70.
53. Markianos, M., Panas, M., Kalfakis, N., and Vassilopoulos, D. (2005). Ann. Neurol. 57, 520-525.
54. Okun, M. S., DeLong, M. R., Hanfelt, J., Gearing, M., and Levey, A. (2004). Neurology 62, 411-413.
55. Cunningham, C. J., Sinnott, M., Denihan, A., et al. (2001). J. Clin. Endocrinol. Metab. 86, 1099-1103.
56. Hoskin, E. K., Tang, M. X., Manly, J. J., and Mayeux, R. (2004). Neurobiol. Aging 25, 141-147.
57. Spratt, D. I., Cox, P., Orav, J., Moloney, J., and Bigos, T. (1993). J. Clin. Endocrinol. Metab. 76, 1548-1554.
58. Wang, C., Chan, V., and Yeung, R. T. (1978). Clin. Endocrinol. (Oxf.) 9, 255-266.
59. Woolf, P. D., Hamill, R. W., McDonald, J. V., Lee, L. A., and Kelly, M. (1985). J. Clin. Endocrinol. Metab. 60, 444-450.
60. Barrett-Connor, E., Khaw, K. T., and Yen, S. S. (1990). Am. J. Epidemiol. 132, 895-901.
61. Andersson, B., Marin, P., Lissner, L., Vermeulen, A., and Bjorntorp, P. (1994). Diabetes Care 17, 405-411.
62. Contoreggi, C. S., Blackman, M. R., Andres, R., et al. (1990). J. Androl. 11, 460-470.
63. McDonald, J. A., Handelsman, D. J., Dilworth, P., Conway, A. J., and McCaughan, G. W. (1993). J. Gastroenterol. Hepatol. 8, 247-253.
64. Handelsman, D. J. and Dong, Q. (1993). Endocrinol. Metab. Clin. North Am. 22, 145-161.
65. Bannister, P., Oakes, J., Sheridan, P., and Losowsky, M. S. (1987). Q. J. Med. 63, 305-313.
66. Elewaut, A., Barbier, F., and Vermeulen, A. (1979). Z. Gastroenterol. 17, 402-405.
67. Moffat, S. D., Zonderman, A. B., Metter, E. J., et al. (2004). Neurology 62, 188-193.
68. Deslypere, J. P. and Vermeulen, A. (1981). J. Clin. Endocrinol. Metab. 53, 430-434.
69. Pardridge, W. M. (1981). Endocr. Rev. 2, 103-123.
70. Twist, S. J., Taylor, G. A., Weddell, A., Weightman, D. R., Edwardson, J. A., and Morris, C. M. (2000). Neurosci. Lett. 286, 1-4.
71. Brinton, R. D. (2004). CNS Drugs 18, 405-422.
72. Raber, J. (2004). Sci. Aging Knowledge Environ. 2004, re2.
73. Strittmatter, W. J. and Roses, A. D. (1996). Annu. Rev. Neurosci. 19, 53-77.
74. Raber, J., Huang, Y., and Ashford, J. W. (2004). Neurobiol. Aging 25, 641-650.
75. Roses, A. D., Saunders, A. M., Corder, E. H., et al. (1995). Arzneimittelforschung 45, 413-417.
76. Raber, J., Bongers, G., LeFevour, A., Buttini, M., and Mucke, L. (2002). J. Neurosci. 22, 5204-5209.
77. Colton, C. A., Brown, C. M., and Vitek, M. P. (2005). Neurobiol. Aging 26, 363-372.
78. Hardy, J. (1997). Trends Neurosci. 20, 154-159.
79. Hardy, J. A. and Higgins, G. A. (1992). Science 256, 184-185.
80. Vincent, B. and Smith, J. D. (2000). Biochem. Biophys. Res. Commun. 271, 82-85.
81. Manthey, D., Heck, S., Engert, S., and Behl, C. (2001). Eur. J. Biochem. 268, 4285-4291.
82. Jaffe, A. B., Toran-Allerand, C. D., Greengard, P., and Gandy, S. E. (1994). J. Biol. Chem. 269, 13065-13068.
83. Greenfield, J. P., Leung, L. W., Cai, D., et al. (2002). J. Biol. Chem. 277, 12128-12136.
84. Savage, M. J., Trusko, S. P., Rowland, D. S., et al. (1998). J. Neurosci. 18, 1743-1752.
85. Xu, H., Gouras, G. K., Greenfield, J. P., et al. (1998). Nat. Med. 4, 447-451.
86. Petanceska, S. S., Nagy, V., Frail, D., and Gandy, S. (2000). Neurology 54, 2212-2217.
87. Zheng, H., Xu, H., Uljon, S. N., et al. (2002). J. Neurochem. 80, 191-196.
88. Levin-Allerhand, J. A., Lominska, C. E., Wang, J., and Smith, J. D. (2002). J. Alzheimers Dis. 4, 449-457.
89. Schonknecht, P., Pantel, J., Klinga, K., et al. (2001). Neurosci. Lett. 307, 122-124.
90. Baker, L. D., Sambamurti, K., Craft, S., et al. (2003). Am. J. Geriatr. Psychiatry 11, 239-244.
91. Gouras, G. K., Xu, H., Gross, R. S., et al. (2000). Proc. Natl. Acad. Scei. USA 97, 1202-1205.
92. Selkoe, D. J. (1989). Ann. Med. 21, 73-76.
93. Poletti, A., Negri-Cesi, P., Melcangi, R. C., Colciago, A., Martini, L., and Celotti, F. (1997). J. Neurochem. 68, 1298-1303.
94. Melcangi, R. C., Celotti, F., Castano, P., and Martini, L. (1992). Brain Res. 585, 411-415.
95. Goodenough, S., Engert, S., and Behl, C. (2000). Neurosci. Lett. 296, 49-52.
96. Ramsden, M., Nyborg, A. C., Murphy, M. P., et al. (2003). J. Neurochem. 87, 1052-1055.
97. Gandy, S., Almeida, O. P., Fonte, J., et al. (2001). JAMA 285, 2195-2196.
98. Almeida, O. P., Waterreus, A., Spry, N., Flicker, L., and Martins, R. N. (2004). Psychoneuroendocrinology 29, 1071-1081.
99. Gillett, M. J., Martins, R. N., Clarnette, R. M., Chubb, S. A., Bruce, D. G., and Yeap, B. B. (2003). J. Alzheimers Dis. 5, 267-269.
100. Nordeen, E. J., Nordeen, K. W., Sengelaub, D. R., and Arnold, A. P. (1985). Science 229, 671-673.
101. Nuñez, J. L., Sodhi, J., and Juraska, J. M. (2002). J. Neurobiol. 52, 312-321.
102. Lund, T. D., Salyer, D. L., Fleming, D. E., and Lephart, E. D. (2000). Dev. Brain Res. 120, 261-266.
103. Sengelaub, D. R., Nordeen, E. J., Nordeen, K. W., and Arnold, A. P. (1989). J. Comp. Neurol. 280, 637-644.
104. Beyer, C., Green, S. J., and Hutchison, J. B. (1994). Endocrinology 135, 1220-1226.
105. Zhang, L., Chang, Y. H., Barker, J. L., et al. (2000). Neurosci. Lett. 281, 57-60.
106. Beyer, C. and Hutchison, J. B. (1997). Dev. Brain Res. 98, 74-81.
107. Marron, T. U., Guerini, V., Rusmini, P., et al. (2005). J. Neurochem. 92, 10-20.
108. Lustig, R. H., Hua, P., Smith, L. S., Wang, C., and Chang, C. (1994). Mol. Cell Neurosci. 5, 587-596.
109. Hauser, K. F., MacLusky, N. J., and Toran-Allerand, C. D. (1987). Brain Res. 406, 62-72.
110. Leranth, C., Petnehazy, O., and MacLusky, N. J. (2003). J. Neurosci. 23, 1588-1592.
111. Leranth, C., Hajszan, T., and MacLusky, N. J. (2004). J. Neurosci. 24, 495-499.
112. Pouliot, W. A., Handa, R. J., and Beck, S. G. (1996). Synapse 23, 10-19.
113. Smith, M. D., Jones, L. S., and Wilson, M. A. (2002). Neuroscience 109, 517-530.
114. Kurz, E. M., Sengelaub, D. R., and Arnold, A. P. (1986). Science 232, 395-398.
115. Brooks, B. P., Merry, D. E., Paulson, H. L., Lieberman, A. P., Kolson, D. L., and Fischbeck, K. H. (1998). J. Neurochem. 70, 1054-1060.
116. Matsumoto, A. (1997). Brain Res. Bull. 44, 539-547.
117. Matsumoto, A. (2001). J. Comp. Neurol. 430, 389-395.
118. Keast, J. R. and Saunders, R. J. (1998). Neuroscience 85, 543-556.
119. Meusburger, S. M. and Keast, J. R. (2001). Neuroscience 108, 331-340.
120. Day, J. R., Laping, N. J., Lampert-Etchells, M., et al. (1993). Neuroscience 55, 435-443.
121. Nichols, N. R., Day, J. R., Laping, N. J., Johnson, S. A., and Finch, C. E. (1993). Neurobiol. Aging 14, 421-429.
122. Laping, N. J., Teter, B., Anderson, C. P., et al. (1994). J. Neurosci. Res. 39, 710-717.
123. Garcia-Segura, L. M., Duenas, M., Busiguina, S., Naftolin, F., and Chowen, J. A. (1995). J. Steroid Biochem. Mol. Biol. 53, 293-298.
124. Garcia-Estrada, J., Del Rio, J. A., Luquin, S., Soriano, E., and Garcia-Segura, L. M. (1993). Brain Res. 628, 271-278.
125. Mong, J. A., Glaser, E., and McCarthy, M. M. (1999). J. Neurosci. 19, 1464-1472.
126. Jones, K. J., Brown, T. J., and Damaser, M. (2001). Brain Res. Brain Res. Rev. 37, 372-382.
127. Yu, W. H. and Srinivasan, R. (1981). Exp. Neurol. 71, 431-435.
128. Yu, W. H. (1982). Exp. Neurol. 77, 129-141.
129. Kujawa, K. A., Tanzer, L., and Jones, K. J. (1995). Exp. Neurol. 133, 138-143.
130. Kujawa, K. A., Emeric, E., and Jones, K. J. (1991). J. Neurosci. 11, 3898-3906.
131. Tanzer, L. and Jones, K. J. (1997). Exp. Neurol. 146, 258-264.
132. Yu, W. H. (1988). Exp. Neurol. 102, 230-235.
133. Yu, W. H. (1989). J. Neurosci. 9, 3908-3914.
134. Huppenbauer, C. B., Tanzer, L., DonCarlos, L. L., and Jones, K. J. (2005). J. Neurosci. 25, 4004-4013.
135. Yu, W. H. and Cao, C. G. (1991). Neuroreport 2, 258-260.
136. Simerly, R. B., Chang, C., Muramatsu, M., and Swanson, L. W. (1990). J. Comp. Neurol. 294, 76-95.
137. Kerr, J. E., Allore, R. J., Beck, S. G., and Handa, R. J. (1995). Endocrinology 136, 3213-3221.
138. Van Hoesen, G. W. and Hyman, B. T. (1990). Prog. Brain Res. 83, 445-457.
139. Hyman, B. T., Van Hoesen, G. W., Damasio, A. R., and Barnes, C. L. (1984). Science 225, 1168-1170.
140. Ramsden, M., Shin, T. M., and Pike, C. J. (2003). Neuroscience 122, 573-578.
141. Azcoitia, I., Sierra, A., Veiga, S., Honda, S., Harada, N., and Garcia-Segura, L. M. (2001). J. Neurobiol. 47, 318-329.
142. Rhodes, M. E. and Frye, C. A. (2004). Pharmacol. Biochem. Behav. 78, 483-493.
143. Rhodes, M. E., Harney, J. P., and Frye, C. A. (2004). Brain Res. 1000, 8-18.
144. Frye, C. A. (2001). Brain Res. Brain Res. Rev. 37, 201-222.
145. Frye, C. A. and Reed, T. A. (1998). Psychoneuroendocrinology 23, 385-399.
146. Dluzen, D. E., McDermott, J. L., and Liu, B. (1996). J. Neurochem. 66, 658-666.
147. Dluzen, D. E. (1996). Brain Res. 715, 113-118.
148. Gao, X. and Dluzen, D. E. (2001). Brain Res. 892, 63-69.
149. Ekue, A., Boulanger, J. F., Morissette, M., and Di Paolo, T. (2002). J. Neuroendocrinol. 14, 731-736.
150. Nishino, H., Nakajima, K., Kumazaki, M., et al. (1998). Neurosci. Res. 30, 303-312.
151. Yang, S. H., Perez, E., Cutright, J., et al. (2002). J. Appl. Physiol. 92, 195-201.
152. Hawk, T., Zhang, Y. Q., Rajakumar, G., Day, A. L., and Simpkins, J. W. (1998). Brain Res. 796, 296-298.
153. Hammond, J., Le, Q., Goodyer, C., Gelfand, M., Trifiro, M., and LeBlanc, A. (2001). J. Neurochem. 77, 1319-1326.
154. Ahlbom, E., Prins, G. S., and Ceccatelli, S. (2001). Brain Res. 892, 255-262.
155. Pike, C. J. (2001). Brain Res. 919, 160-165.
156. Zhang, Y., Champagne, N., Beitel, L. K., Goodyer, C. G., Trifiro, M., and LeBlanc, A. (2004). J. Neurosci. 24, 5315-5321.
157. Papasozomenos, S. C. H. and Shanavas, A. (2002). Proc. Natl. Acad. Sci. USA 99, 1140-1145.
158. Nguyen, T. V., Yao, M., and Pike, C. J. (2005). J. Neurochem. 94, 1639-1651.
159. Kelly, S. and Yenari, M. A. (2002). Curr. Med. Res. Opin. 18(Suppl. 2), s55-s60.
160. Gregory, C. W. and Bowen, R. L. (2005). Cell. Mol. Life Sci. 62, 313-319.
161. Short, R. A., Bowen, R. L., O'Brien, P. C., and Graff-Radford, N. R. (2001). Mayo Clin. Proc. 76, 906-909.
162. Drouin, J. and Labrie, F. (1976). Endocrinology 98, 1528-1534.
163. Gill, M. K., Karanth, S., Dutt, A., and Juneja, H. S. (1985). Horm. Metab. Res. 17, 141-146.
164. Lindzey, J., Wetsel, W. C., Couse, J. F., Stoker, T., Cooper, R., and Korach, K. S. (1998). Endocrinology 139, 4092-4101.
165. Bowen, R. L., Verdile, G., Liu, T., et al. (2004). J. Biol. Chem. 279, 20539-20545.