Concurrent testing of digital microfluidics-based biochips

ACM Transactions on Design Automation of Electronic Systems

Volumn 11, Issue 2, 2006, Pages 442-464

  Su, Fei ^a,b   Ozev, Sule ^a,b   Chakrabarty, Krishnendu ^a,b  

^a DUKE UNIVERSITY   (United States)

^b USA   (United States)

Author keywords

Biochips; Catastrophic faults; Concurrent testing; Microfluidics

Indexed keywords

EID: 33746104081     PISSN: 10844309     EISSN: 10844309     Source Type: Journal    
DOI: 10.1145/1142155.1142164     Document Type: Article

References (37)

1. BALCH, T. AND ARKIN, R. 1993. Avoiding the past: a simple, but effective strategy for reactive navigation. In Proceedings of the International Conference on Robotics and Automation, 678-685.
2. BERKELAAR, M. lpsolve. Eindhoven Univ. Technol., Eindhoven, The Netherlands [Online]. Available at ftp://ftp.ics.ele.tue.nl/pub/lp.solve.
3. CHO, S. K., FAN, S. K., MOON, H., AND KIM, C. J. 2002. Toward digital microfluidic circuits: Creating, transporting, cutting and merging liquid droplets by electrowetting-based actuation. In Proceedings of the IEEE Conference on MEMS. IEEE Computer Society Press, Los Alamitos, CA, 32-52.
4. DAVIES, B. 1995. Robotics in minimally invasive surgery. In Proceedings of the IEE Colloquium. Through the Keyhole: Microengoneering in Minimally Invasive Surgery, 5/1-5/2.
5. DEB, N. AND BLANTON, R. D. 2000. Analysis of failure sources in surface-micromachined MEMS. In Proceedings of the IEEE International Test Conference. IEEE Computer Society Press, Los Alamitos, CA, 739-749.
6. DEB, N. AND BLANTON, R. D. 2004. Multi-modal built-in self-test for symmetric microsystems. In Proceedings of the IEEE VLSI Test Symposium. IEEE Computer Society Press, Los Alamitos, CA, 139-147.
7. DHAYNI, AL, MIR, S. AND RUFER, L. 2004. MEMS built-in-self-test using MLS. In Proceedings of the European Test Symposium, 66-71.
8. DUMAS, N., AZAIS, F., LATORRE, L., AND NOUET, P. 2004. Electrically-induced thermal stimuli for MEMS testing. In Proceedings of the European Test Symposium, 60-65.
9. GRAHAM, R., LAWLER, E., LENSTRA, J., AND KAN, A. R. 1979. Optimization and approximation in deterministic sequencing and scheduling: A survey. Ann. Disc. Math. 5, 287-326.
10. HENNING, A. K. 1998. Microfluidic MEMS. In Proceedings of the IEEE Aerospace Conference. IEEE Computer Society Press, Los Alamitos, CA, 471-486.
11. HULL, H. F., DANILA, R., AND EHRESMANN, K. 2003. Smallpox and bioterrorism: Public-health responses. J. Lab. Clin. Med. 142, 221-228.
12. INTERNATIONAL TECHNOLOGY ROADMAP FOR SEMICONDUCTORS (ITRS), http://public.itrs.net/Files/2003ITRS/Home2003.htm.
13. KERKHOFF, H. G. 1999. Testing philosophy behind the micro analysis system. In Proceedings of the SPIE: Design, Test and Microfabrication of MEMS and MOEMS. 78-83.
14. KERKHOFF, H. G. AND ACAR, M. 2003. Testable design and testing of micro-electro-fluidic arrays. In Proceedings of the IEEE VLSI Test Symposium. IEEE Computer Society Press, Los Alamitos, CA, 403-409.
15. KERKHOFF, H. G. AND HENDRIKS, H. P. A. 2001. Fault modeling and fault simulation in mixed micro-fluidic microelectronic systems. J. Elect. Test. Theory. Appl. 17, 427-437.
16. KOLPEKWAR, A. AND BLANTON, R. D. 1997. Development of a MEMS testing methodology. In Proceedings of the IEEE Inernational Test Conference. IEEE Computer Society Press, Los Alamitos, CA, 923-931.
17. MIR, S., CHARLOT, B., AND COURTOIS, B. 2000. Extending fault-based testing to microelectromechanical systems. J. Elect. Test. Theory Appl. 16, 279-288.
18. PAIK, P., PAMULA, V. K., AND FAIR, R. B. 2003. Rapid droplet mixers for digital microfluidic systems. Lab on a Chip 3, 253-259.
19. POUL, J. 2002. Bioterrorism and biodefence, J. Infect. 44, 59-66.
20. POLLACK, M. G., FAIR, R. B., AND SHENDEROV, A. D. 2000. Electrowetting-based actuation of liquid droplets for microfluidic applications. Appl. Phys. Lett. 77, 1725-1726.
21. POLLACK, M. G., SHENDERO, A. D., AND FAIR, R. B. 2002. Electrowetting-based actuation of droplets for integrated microfluidics. Lab on a Chip 2, 96-101.
22. POLLACK, M. G., PAIK, P. Y., SHENDERO, A. D., PAMULA, V. K., DIETRICH, F. S., AND FAIR, R. B. 2003. Investigation of electrowetting-based microfluidics for real-time PCR applications. In Proceedings of μTAS. 619-622.
23. REN, H. AND FAIR, R. B. 2002. Micro/nano liter droplet formation and dispensing by capacitance metering and electrowetting actuation. Technical Digest IEEE-NANO, 36-38.
24. SCHULTE, T. H., BARDELL, R. L., AND WEIGL, B. H. 2002. Microfluidic technologies in clinical diagnostics. Clinica Chimica Acta 321, 1-10.
25. SRINIVASAN, V., PAMULA, V. K., POLLACK, M. G., AND FAIR, R. B. 2003a. A digital microfluidic biosensor for multianalyte detection. In Proceedings of the IEEE Conference on MEMS. IEEE Computer Society Press, Los Alamitos, CA, 327-330.
26. SRINIVASAN, V., PAMULA, V. K., POLLACK, M. G., AND FAIR, R. B. 2003b. Clinical diagnostics on human whole blood, plasma, serum, urine, saliva, sweat, and tears on a digital microfluidic platform. In Proceedings of μTAS, 1287-1290.
27. SRINIVASAN, V., PAMULA, V. K., AND FAIR, R. B. 2004. An integrated digital microfluidic lab-on-a-chip for clinical diagnostics on human physiological fluids. Lab on a Chip 4, 310-315.
28. SU, F. AND CHAKRABARTY, K. 2004. Architectural-level synthesis of digital microfluidics-based biochips. In Proceedings of the IEEE International Conference on CAD. IEEE Computer Society Press, Los Alamitos,CA, 223-228.
29. SU, F. AND CHAKRABARTY, K. 2005. Design of fault-tolerant and dynamically-reconflgurable microfluidic biochips. In Proceedings of the Design, Automation and Test in Europe (DATE) Conference. 1202-1207.
30. SU, F., OZEV, S., AND CHAKRABARTY, K. 2004. Test planning And test resource optimization for droplet-based microfluidic systems. In Proceedings of the European Test Symposium, 72-77.
31. SU, F., OZEV, S., AND CHAKRABARTY, K. 2005. Ensuring the operational health of droplet-based microelectrofluidic biosensor systems. IEEE Sens. J. 5, 763-773.
32. THORSEN, T., MAERKL, S., AND QUAKE, S. 2002. Microfluidic large-scale integration. Science 298, 580-584.
33. TRINDER, P. 1969. Determination of glucose in blood using glucose oxidase with an alternative oxygen acceptor. Ann. Clin. Biochem. 6, 24-27.
34. VENKATESH, S. AND MEMISH, Z. A. 2003. Bioterrorism: A new challenge for public health. Int. J. Antimicro. Agents 21, 200-206.
35. VERPOORTE, E. AND DE ROOIJ, N. F. 2003. Microfluidics meets MEMS, Proc. IEEE 91, 930-953.
36. Videos on droplet transport, dispensing, mixing and biomedical assays [Online]. Available at http://www.ee.duke.edu/Research/microfluidics
37. ZHANG, T., CHAKRABARTY, K., AND FAIRS, R. B. 2002. Microelectrofluidic Systems: Modeling and Simulation. CRC Press, Boca Raton, FL.