메뉴 건너뛰기




Volumn 108, Issue 2, 2006, Pages 426-431

Regulatory T-cell compartmentalization and trafficking

Author keywords

[No Author keywords available]

Indexed keywords

CHEMOKINE RECEPTOR; INTEGRIN; INTERLEUKIN 2; TRANSCRIPTION FACTOR FOXP3;

EID: 33745968543     PISSN: 00064971     EISSN: 00064971     Source Type: Journal    
DOI: 10.1182/blood-2006-01-0177     Document Type: Review
Times cited : (266)

References (95)
  • 1
    • 0036467505 scopus 로고    scopus 로고
    • The role of chemokines in linking innate and adaptive immunity
    • Luster AD. The role of chemokines in linking innate and adaptive immunity. Curr Opin Immunol. 2002;14:129-135.
    • (2002) Curr Opin Immunol , vol.14 , pp. 129-135
    • Luster, A.D.1
  • 2
    • 0037364976 scopus 로고    scopus 로고
    • Regulatory lymphocytes: Regulatory T cells in transplantation tolerance
    • Wood KJ, Sakaguchi S. Regulatory lymphocytes: regulatory T cells in transplantation tolerance. Nat Rev Immunol. 2003;3:199-210.
    • (2003) Nat Rev Immunol , vol.3 , pp. 199-210
    • Wood, K.J.1    Sakaguchi, S.2
  • 3
    • 0037361819 scopus 로고    scopus 로고
    • Regulatory lymphocytes: Antigen-induced regulatory T cells in autoimmunity
    • Von Herrath MG, Harrison LC. Regulatory lymphocytes: antigen-induced regulatory T cells in autoimmunity. Nat Rev Immunol. 2003;3:223-232.
    • (2003) Nat Rev Immunol , vol.3 , pp. 223-232
    • Von Herrath, M.G.1    Harrison, L.C.2
  • 4
    • 0036597371 scopus 로고    scopus 로고
    • CD4+ CD25+ suppressor T cells: More questions than answers
    • Shevach EM. CD4+ CD25+ suppressor T cells: more questions than answers. Nat Rev Immunol. 2002;2:389-400.
    • (2002) Nat Rev Immunol , vol.2 , pp. 389-400
    • Shevach, E.M.1
  • 5
    • 0142250482 scopus 로고    scopus 로고
    • Regulatory lymphocytes: Regulatory T cells under scrutiny
    • Francois Bach J. Regulatory lymphocytes: regulatory T cells under scrutiny. Nat Rev Immunol. 2003;3:189-198.
    • (2003) Nat Rev Immunol , vol.3 , pp. 189-198
    • Francois Bach, J.1
  • 6
    • 2142752959 scopus 로고    scopus 로고
    • Type 1 T regulatory cells and their relationship with CD4+CD25+ T regulatory cells
    • Roncarolo MG, Gregori S, Levings M. Type 1 T regulatory cells and their relationship with CD4+CD25+ T regulatory cells. Novartis Found Symp. 2003;252:115-127; discussion 127-131, 203-110.
    • (2003) Novartis Found Symp , vol.252 , pp. 115-127
    • Roncarolo, M.G.1    Gregori, S.2    Levings, M.3
  • 7
    • 16844379997 scopus 로고    scopus 로고
    • Immunosuppressive networks in the tumour environment and their therapeutic relevance
    • Zou W. Immunosuppressive networks in the tumour environment and their therapeutic relevance. Nat Rev Cancer. 2005;5:263-274.
    • (2005) Nat Rev Cancer , vol.5 , pp. 263-274
    • Zou, W.1
  • 8
    • 33645286546 scopus 로고    scopus 로고
    • Regulatory T cells, tumour immunity and immunotherapy
    • Zou W. Regulatory T cells, tumour immunity and immunotherapy. Nat Rev Immunol. 2006;6:295-307.
    • (2006) Nat Rev Immunol , vol.6 , pp. 295-307
    • Zou, W.1
  • 9
    • 16844363097 scopus 로고    scopus 로고
    • A well adapted regulatory contrivance: Regulatory T cell development and the forkhead family transcription factor Foxp3
    • Fontenot JD, Rudensky AY. A well adapted regulatory contrivance: regulatory T cell development and the forkhead family transcription factor Foxp3. Nat Immunol. 2005;6:331-337.
    • (2005) Nat Immunol , vol.6 , pp. 331-337
    • Fontenot, J.D.1    Rudensky, A.Y.2
  • 10
    • 16844365788 scopus 로고    scopus 로고
    • Naturally arising Foxp3-expressing CD25+CD4+ regulatory T cells in immunological tolerance to self and non-self
    • Sakaguchi S. Naturally arising Foxp3-expressing CD25+CD4+ regulatory T cells in immunological tolerance to self and non-self. Nat Immunol. 2005;6:345-352.
    • (2005) Nat Immunol , vol.6 , pp. 345-352
    • Sakaguchi, S.1
  • 11
    • 16844378209 scopus 로고    scopus 로고
    • Natural regulatory T cells and self-tolerance
    • Schwartz RH. Natural regulatory T cells and self-tolerance. Nat Immunol. 2005;6:327-330.
    • (2005) Nat Immunol , vol.6 , pp. 327-330
    • Schwartz, R.H.1
  • 12
    • 16844362608 scopus 로고    scopus 로고
    • Mechanisms of suppression by suppressor T cells
    • von Boehmer H. Mechanisms of suppression by suppressor T cells. Nat Immunol. 2005;6:338-344.
    • (2005) Nat Immunol , vol.6 , pp. 338-344
    • Von Boehmer, H.1
  • 13
    • 17144405680 scopus 로고    scopus 로고
    • Potential role of interleukin-10-secreting regulatory T cells in allergy and asthma
    • Hawrylowicz CM, O'Garra A. Potential role of interleukin-10-secreting regulatory T cells in allergy and asthma. Nat Rev Immunol. 2005;5:271-283.
    • (2005) Nat Rev Immunol , vol.5 , pp. 271-283
    • Hawrylowicz, C.M.1    O'Garra, A.2
  • 14
    • 8544242704 scopus 로고    scopus 로고
    • Regulatory T cells: Friend or foe in immunity to infection?
    • Mills KH. Regulatory T cells: friend or foe in immunity to infection? Nat Rev Immunol. 2004;4:841-855.
    • (2004) Nat Rev Immunol , vol.4 , pp. 841-855
    • Mills, K.H.1
  • 15
    • 16844369607 scopus 로고    scopus 로고
    • Natural regulatory T cells in infectious disease
    • Belkaid Y, Rouse BT. Natural regulatory T cells in infectious disease. Nat Immunol. 2005;6:353-360.
    • (2005) Nat Immunol , vol.6 , pp. 353-360
    • Belkaid, Y.1    Rouse, B.T.2
  • 16
    • 8544281696 scopus 로고    scopus 로고
    • Bone marrow is a reservoir for CD4+CD25+ regulatory T cells that traffic through CXCL12/CXCR4 signals
    • Zou L, Barnett B, Safah H, et al. Bone marrow is a reservoir for CD4+CD25+ regulatory T cells that traffic through CXCL12/CXCR4 signals. Cancer Res. 2004;64:8451-8455.
    • (2004) Cancer Res , vol.64 , pp. 8451-8455
    • Zou, L.1    Barnett, B.2    Safah, H.3
  • 17
    • 4644237613 scopus 로고    scopus 로고
    • Specific recruitment of regulatory T cells in ovarian carcinoma fosters immune privilege and predicts reduced survival
    • Curiel TJ, Coukos G, Zou L, et al. Specific recruitment of regulatory T cells in ovarian carcinoma fosters immune privilege and predicts reduced survival. Nat Med. 2004;10:942-949.
    • (2004) Nat Med , vol.10 , pp. 942-949
    • Curiel, T.J.1    Coukos, G.2    Zou, L.3
  • 18
    • 0035054606 scopus 로고    scopus 로고
    • Human CD4(+)CD25(+) thymocytes and peripheral T cells have immune suppressive activity in vitro
    • Stephens LA, Mottet C, Mason D, Powrie F. Human CD4(+)CD25(+) thymocytes and peripheral T cells have immune suppressive activity in vitro. Eur J Immunol. 2001;31:1247-1254.
    • (2001) Eur J Immunol , vol.31 , pp. 1247-1254
    • Stephens, L.A.1    Mottet, C.2    Mason, D.3    Powrie, F.4
  • 19
    • 0033985780 scopus 로고    scopus 로고
    • Suppressor effector function of CD4+CD25+ immunoregulatory T cells is antigen nonspecific
    • Thornton AM, Shevach EM. Suppressor effector function of CD4+CD25+ immunoregulatory T cells is antigen nonspecific. J Immunol. 2000;164:183-190.
    • (2000) J Immunol , vol.164 , pp. 183-190
    • Thornton, A.M.1    Shevach, E.M.2
  • 20
    • 0036721772 scopus 로고    scopus 로고
    • The subpopulation of CD4+CD25+ splenocytes that delays adoptive transfer of diabetes expresses L-selectin and high levels of CCR7
    • Szanya V, Ermann J, Taylor C, Holness C, Fathman CG. The subpopulation of CD4+CD25+ splenocytes that delays adoptive transfer of diabetes expresses L-selectin and high levels of CCR7. J Immunol. 2002;169:2461-2465.
    • (2002) J Immunol , vol.169 , pp. 2461-2465
    • Szanya, V.1    Ermann, J.2    Taylor, C.3    Holness, C.4    Fathman, C.G.5
  • 21
    • 14944346738 scopus 로고    scopus 로고
    • Only the CD62L+ subpopulation of CD4+CD25+ regulatory T cells protects from lethal acute GVHD
    • Ermann J, Hoffmann P, Edinger M, et al. Only the CD62L+ subpopulation of CD4+CD25+ regulatory T cells protects from lethal acute GVHD. Blood. 2005;105:2220-2226.
    • (2005) Blood , vol.105 , pp. 2220-2226
    • Ermann, J.1    Hoffmann, P.2    Edinger, M.3
  • 22
    • 9444280125 scopus 로고    scopus 로고
    • L-Selectin(hi) but not the L-selectin(lo) CD4+25+ T-regulatory cells are potent inhibitors of GVHD and BM graft rejection
    • Taylor PA, Panoskaltsis-Mortari A, Swedin JM, et al. L-Selectin(hi) but not the L-selectin(lo) CD4+25+ T-regulatory cells are potent inhibitors of GVHD and BM graft rejection. Blood. 2004;104:3804-3812.
    • (2004) Blood , vol.104 , pp. 3804-3812
    • Taylor, P.A.1    Panoskaltsis-Mortari, A.2    Swedin, J.M.3
  • 23
    • 21044449573 scopus 로고    scopus 로고
    • Lymph node occupancy is required for the peripheral development of alloantigen-specific Foxp3+ regulatory T cells
    • Ochando JC, Yopp AC, Yang Y, et al. Lymph node occupancy is required for the peripheral development of alloantigen-specific Foxp3+ regulatory T cells. J Immunol. 2005;174:6993-7005.
    • (2005) J Immunol , vol.174 , pp. 6993-7005
    • Ochando, J.C.1    Yopp, A.C.2    Yang, Y.3
  • 24
    • 0035903307 scopus 로고    scopus 로고
    • Unique chemotactic response profile and specific expression of chemokine receptors CCR4 and CCR8 by CD4(+)CD25(+) regulatory T cells
    • Iellem A, Mariani M, Lang R, et al. Unique chemotactic response profile and specific expression of chemokine receptors CCR4 and CCR8 by CD4(+)CD25(+) regulatory T cells. J Exp Med. 2001;194:847-853.
    • (2001) J Exp Med , vol.194 , pp. 847-853
    • Iellem, A.1    Mariani, M.2    Lang, R.3
  • 25
    • 15244363080 scopus 로고    scopus 로고
    • Regulatory T cells can migrate to follicles upon T cell activation and suppress GC-Th cells and GC-Th cell-driven B cell responses
    • Lim HW, Hillsamer P, Kim CH. Regulatory T cells can migrate to follicles upon T cell activation and suppress GC-Th cells and GC-Th cell-driven B cell responses. J Clin Invest. 2004;114:1640-1649.
    • (2004) J Clin Invest , vol.114 , pp. 1640-1649
    • Lim, H.W.1    Hillsamer, P.2    Kim, C.H.3
  • 26
    • 9144267705 scopus 로고    scopus 로고
    • Dual role of CCR2 during initiation and progression of collagen-induced arthritis: Evidence for regulatory activity of CCR2+ T cells
    • Bruhl H, Cihak J, Schneider MA, et al. Dual role of CCR2 during initiation and progression of collagen-induced arthritis: evidence for regulatory activity of CCR2+ T cells. J Immunol. 2004;172:890-898.
    • (2004) J Immunol , vol.172 , pp. 890-898
    • Bruhl, H.1    Cihak, J.2    Schneider, M.A.3
  • 27
    • 17144393320 scopus 로고    scopus 로고
    • Recruitment of Foxp3+ T regulatory cells mediating allograft tolerance depends on the CCR4 chemokine receptor
    • Lee I, Wang L, Wells AD, Dorf ME, Ozkaynak E, Hancock WW. Recruitment of Foxp3+ T regulatory cells mediating allograft tolerance depends on the CCR4 chemokine receptor. J Exp Med. 2005;201:1037-1044.
    • (2005) J Exp Med , vol.201 , pp. 1037-1044
    • Lee, I.1    Wang, L.2    Wells, A.D.3    Dorf, M.E.4    Ozkaynak, E.5    Hancock, W.W.6
  • 28
    • 27644497249 scopus 로고    scopus 로고
    • Critical role for CCR5 in the function of donor CD4+CD25+ regulatory T cells during acute graft-versus-host disease
    • Wysocki CA, Jiang Q, Panoskaltsis-Mortari A, et al. Critical role for CCR5 in the function of donor CD4+CD25+ regulatory T cells during acute graft-versus-host disease. Blood. 2005;106:3300-3307.
    • (2005) Blood , vol.106 , pp. 3300-3307
    • Wysocki, C.A.1    Jiang, Q.2    Panoskaltsis-Mortari, A.3
  • 29
    • 1642454711 scopus 로고    scopus 로고
    • Ultraviolet radiation-induced regulatory T cells not only inhibit the induction but can suppress the effector phase of contact hypersensitivity
    • Schwarz A, Maeda A, Wild MK, et al. Ultraviolet radiation-induced regulatory T cells not only inhibit the induction but can suppress the effector phase of contact hypersensitivity. J Immunol. 2004;172:1036-1043.
    • (2004) J Immunol , vol.172 , pp. 1036-1043
    • Schwarz, A.1    Maeda, A.2    Wild, M.K.3
  • 30
    • 27144524938 scopus 로고    scopus 로고
    • Migration matters: Regulatory T-cell compartmentalization determines suppressive activity in vivo
    • Siegmund K, Feuerer M, Siewert C, et al. Migration matters: regulatory T-cell compartmentalization determines suppressive activity in vivo. Blood. 2005;106:3097-3104.
    • (2005) Blood , vol.106 , pp. 3097-3104
    • Siegmund, K.1    Feuerer, M.2    Siewert, C.3
  • 31
    • 17844364002 scopus 로고    scopus 로고
    • A role for CD103 in the retention of CD4+CD25+ Treg and control of Leishmania major infection
    • Suffia I, Reckling SK, Salay G, Belkaid Y. A role for CD103 in the retention of CD4+CD25+ Treg and control of Leishmania major infection. J Immunol. 2005;174:5444-5455.
    • (2005) J Immunol , vol.174 , pp. 5444-5455
    • Suffia, I.1    Reckling, S.K.2    Salay, G.3    Belkaid, Y.4
  • 32
    • 0036791004 scopus 로고    scopus 로고
    • Expression of the integrin alpha Ebeta 7 identifies unique subsets of CD25+ as well as CD25- regulatory T cells
    • U S A
    • Lehmann J, Huehn J, de la Rosa M, et al. Expression of the integrin alpha Ebeta 7 identifies unique subsets of CD25+ as well as CD25- regulatory T cells. Proc Natl Acad Sci U S A. 2002;99:13031-13036.
    • (2002) Proc Natl Acad Sci , vol.99 , pp. 13031-13036
    • Lehmann, J.1    Huehn, J.2    De La Rosa, M.3
  • 33
    • 10744221289 scopus 로고    scopus 로고
    • Developmental stage, phenotype, and migration distinguish naive- and effector/memory-like CD4+ regulatory T cells
    • Huehn J, Siegmund K, Lehmann JC, et al. Developmental stage, phenotype, and migration distinguish naive- and effector/memory-like CD4+ regulatory T cells. J Exp Med. 2004;199:303-313.
    • (2004) J Exp Med , vol.199 , pp. 303-313
    • Huehn, J.1    Siegmund, K.2    Lehmann, J.C.3
  • 34
    • 10844222790 scopus 로고    scopus 로고
    • Dysfunctional blood and target tissue CD4+CD25high regulatory T cells in psoriasis: Mechanism underlying unrestrained pathogenic effector T cell proliferation
    • Sugiyama H, Gyulai R, Toichi E, et al. Dysfunctional blood and target tissue CD4+CD25high regulatory T cells in psoriasis: mechanism underlying unrestrained pathogenic effector T cell proliferation. J Immunol. 2005;174:164-173.
    • (2005) J Immunol , vol.174 , pp. 164-173
    • Sugiyama, H.1    Gyulai, R.2    Toichi, E.3
  • 35
    • 24944583626 scopus 로고    scopus 로고
    • Chemokine receptor CCR7 guides T cell exit from peripheral tissues and entry into afferent lymphatics
    • Bromley SK, Thomas SY, Luster AD. Chemokine receptor CCR7 guides T cell exit from peripheral tissues and entry into afferent lymphatics. Nat Immunol. 2005;6:895-901.
    • (2005) Nat Immunol , vol.6 , pp. 895-901
    • Bromley, S.K.1    Thomas, S.Y.2    Luster, A.D.3
  • 36
    • 24944569742 scopus 로고    scopus 로고
    • Chemokine receptor CCR7 required for T lymphocyte exit from peripheral tissues
    • Debes GF, Arnold CN, Young AJ, et al. Chemokine receptor CCR7 required for T lymphocyte exit from peripheral tissues. Nat Immunol. 2005;6:889-894.
    • (2005) Nat Immunol , vol.6 , pp. 889-894
    • Debes, G.F.1    Arnold, C.N.2    Young, A.J.3
  • 37
    • 0028607003 scopus 로고
    • Production and selection of B lymphocytes in bone marrow: Lymphostromal interactions and apoptosis in normal, mutant and transgenic mice
    • Osmond DG. Production and selection of B lymphocytes in bone marrow: lymphostromal interactions and apoptosis in normal, mutant and transgenic mice. Adv Exp Med Biol. 1994;355:15-20.
    • (1994) Adv Exp Med Biol , vol.355 , pp. 15-20
    • Osmond, D.G.1
  • 38
  • 39
    • 12444303174 scopus 로고    scopus 로고
    • Bone marrow is a preferred site for homeostatic proliferation of memory CD8 T cells
    • Becker TC, Coley SM, Wherry EJ, Ahmed R. Bone marrow is a preferred site for homeostatic proliferation of memory CD8 T cells. J Immunol. 2005;174:1269-1273.
    • (2005) J Immunol , vol.174 , pp. 1269-1273
    • Becker, T.C.1    Coley, S.M.2    Wherry, E.J.3    Ahmed, R.4
  • 40
    • 13844272211 scopus 로고    scopus 로고
    • Bone marrow is a major reservoir and site of recruitment for central memory CD8+ T cells
    • Mazo IB, Honczarenko M, Leung H, et al. Bone marrow is a major reservoir and site of recruitment for central memory CD8+ T cells. Immunity. 2005;22:259-270.
    • (2005) Immunity , vol.22 , pp. 259-270
    • Mazo, I.B.1    Honczarenko, M.2    Leung, H.3
  • 41
    • 0031569542 scopus 로고    scopus 로고
    • Bone marrow can function as a lymphoid organ during a primary immune response under conditions of disrupted lymphocyte trafficking
    • Tripp RA, Topham DJ, Watson SR, Doherty PC. Bone marrow can function as a lymphoid organ during a primary immune response under conditions of disrupted lymphocyte trafficking. J Immunol. 1997;158:3716-3720.
    • (1997) J Immunol , vol.158 , pp. 3716-3720
    • Tripp, R.A.1    Topham, D.J.2    Watson, S.R.3    Doherty, P.C.4
  • 42
    • 0141796315 scopus 로고    scopus 로고
    • Bone marrow as a priming site for T-cell responses to blood-borne antigen
    • Feuerer M, Beckhove P, Garbi N, et al. Bone marrow as a priming site for T-cell responses to blood-borne antigen. Nat Med. 2003;9:1151-1157.
    • (2003) Nat Med , vol.9 , pp. 1151-1157
    • Feuerer, M.1    Beckhove, P.2    Garbi, N.3
  • 43
    • 0035048973 scopus 로고    scopus 로고
    • Therapy of human tumors in NOD/SCID mice with patient-derived reactivated memory T cells from bone marrow
    • Feuerer M, Beckhove P, Bai L, et al. Therapy of human tumors in NOD/SCID mice with patient-derived reactivated memory T cells from bone marrow. Nat Med. 2001;7:452-458.
    • (2001) Nat Med , vol.7 , pp. 452-458
    • Feuerer, M.1    Beckhove, P.2    Bai, L.3
  • 44
    • 0035314014 scopus 로고    scopus 로고
    • Enrichment of memory T cells and other profound immunological changes in the bone marrow from untreated breast cancer patients
    • Feuerer M, Rocha M, Bai L, et al. Enrichment of memory T cells and other profound immunological changes in the bone marrow from untreated breast cancer patients. Int J Cancer. 2001;92:96-105.
    • (2001) Int J Cancer , vol.92 , pp. 96-105
    • Feuerer, M.1    Rocha, M.2    Bai, L.3
  • 45
    • 17044430217 scopus 로고    scopus 로고
    • Identifying Foxp3-expressing suppressor T cells with a bicistronic reporter
    • U S A
    • Wan YY, Flavell RA. Identifying Foxp3-expressing suppressor T cells with a bicistronic reporter. Proc Natl Acad Sci U S A. 2005;102:5126-5131.
    • (2005) Proc Natl Acad Sci , vol.102 , pp. 5126-5131
    • Wan, Y.Y.1    Flavell, R.A.2
  • 46
    • 0347785480 scopus 로고    scopus 로고
    • Control of regulatory T cell development by the transcription factor Foxp3
    • Hori S, Nomura T, Sakaguchi S. Control of regulatory T cell development by the transcription factor Foxp3. Science. 2003;299:1057-1061.
    • (2003) Science , vol.299 , pp. 1057-1061
    • Hori, S.1    Nomura, T.2    Sakaguchi, S.3
  • 48
    • 0032076635 scopus 로고    scopus 로고
    • Potent and selective stimulation of memory-phenotype CD8+ T cells in vivo by IL-15
    • Zhang X, Sun S, Hwang I, Tough DF, Sprent J. Potent and selective stimulation of memory-phenotype CD8+ T cells in vivo by IL-15. Immunity. 1998;8:591-599.
    • (1998) Immunity , vol.8 , pp. 591-599
    • Zhang, X.1    Sun, S.2    Hwang, I.3    Tough, D.F.4    Sprent, J.5
  • 50
    • 0037124341 scopus 로고    scopus 로고
    • Interleukin 15 is required for proliferative renewal of virus-specific memory CD8 T cells
    • Becker TC, Wherry EJ, Boone D, et al. Interleukin 15 is required for proliferative renewal of virus-specific memory CD8 T cells. J Exp Med. 2002;195:1541-1548.
    • (2002) J Exp Med , vol.195 , pp. 1541-1548
    • Becker, T.C.1    Wherry, E.J.2    Boone, D.3
  • 51
    • 9144241114 scopus 로고    scopus 로고
    • Cutting edge: Transpresentation of IL-15 by bone marrow-derived cells necessitates expression of IL-15 and IL-15R alpha by the same cells
    • Sandau MM, Schluns KS, Lefrancois L, Jameson SC. Cutting edge: transpresentation of IL-15 by bone marrow-derived cells necessitates expression of IL-15 and IL-15R alpha by the same cells. J Immunol. 2004;173:6537-6541.
    • (2004) J Immunol , vol.173 , pp. 6537-6541
    • Sandau, M.M.1    Schluns, K.S.2    Lefrancois, L.3    Jameson, S.C.4
  • 52
    • 5444239242 scopus 로고    scopus 로고
    • Coordinate expression and trans presentation of interleukin (IL)-15Ralpha and IL-15 supports natural killer cell and memory CD8+ T cell homeostasis
    • Burkett PR, Koka R, Chien M, Chai S, Boone DL, Ma A. Coordinate expression and trans presentation of interleukin (IL)-15Ralpha and IL-15 supports natural killer cell and memory CD8+ T cell homeostasis. J Exp Med. 2004;200:825-834.
    • (2004) J Exp Med , vol.200 , pp. 825-834
    • Burkett, P.R.1    Koka, R.2    Chien, M.3    Chai, S.4    Boone, D.L.5    Ma, A.6
  • 53
    • 0035874949 scopus 로고    scopus 로고
    • Regulatory CD4(+)CD25(+) T cells in tumors from patients with early- stage non-small cell lung cancer and late-stage ovarian cancer
    • Woo EY, Chu CS, Goletz TJ, et al. Regulatory CD4(+)CD25(+) T cells in tumors from patients with early- stage non-small cell lung cancer and late-stage ovarian cancer. Cancer Res. 2001;61:4766-4772.
    • (2001) Cancer Res , vol.61 , pp. 4766-4772
    • Woo, E.Y.1    Chu, C.S.2    Goletz, T.J.3
  • 54
    • 0036721629 scopus 로고    scopus 로고
    • Prevalence of regulatory T cells is increased in peripheral blood and tumor microenvironment of patients with pancreas or breast adenocarcinoma
    • Liyanage UK, Moore TT, Joo HG, et al. Prevalence of regulatory T cells is increased in peripheral blood and tumor microenvironment of patients with pancreas or breast adenocarcinoma. J Immunol. 2002;169:2756-2761.
    • (2002) J Immunol , vol.169 , pp. 2756-2761
    • Liyanage, U.K.1    Moore, T.T.2    Joo, H.G.3
  • 55
    • 0037105759 scopus 로고    scopus 로고
    • Inhibition of cytolytic T lymphocyte proliferation by autologous CD4+/CD25+ regulatory T cells in a colorectal carcinoma patient is mediated by transforming growth factor-beta
    • Somasundaram R, Jacob L, Swoboda R, et al. Inhibition of cytolytic T lymphocyte proliferation by autologous CD4+/CD25+ regulatory T cells in a colorectal carcinoma patient is mediated by transforming growth factor-beta. Cancer Res. 2002;62:5267-5272.
    • (2002) Cancer Res , vol.62 , pp. 5267-5272
    • Somasundaram, R.1    Jacob, L.2    Swoboda, R.3
  • 57
    • 0141891466 scopus 로고    scopus 로고
    • Increased populations of regulatory T cells in peripheral blood and tumor-infiltrating lymphocytes in patients with gastric and esophageal cancers
    • Ichihara F, Kono K, Takahashi A, Kawaida H, Sugai H, Fujii H. Increased populations of regulatory T cells in peripheral blood and tumor-infiltrating lymphocytes in patients with gastric and esophageal cancers. Clin Cancer Res. 2003;9:4404-4408.
    • (2003) Clin Cancer Res , vol.9 , pp. 4404-4408
    • Ichihara, F.1    Kono, K.2    Takahashi, A.3    Kawaida, H.4    Sugai, H.5    Fujii, H.6
  • 58
    • 0041386189 scopus 로고    scopus 로고
    • CD4+CD25+ regulatory T cells in patients with gastrointestinal malignancies: Possible involvement of regulatory T cells in disease progression
    • Sasada T, Kimura M, Yoshida Y, Kanai M, Takabayashi A. CD4+CD25+ regulatory T cells in patients with gastrointestinal malignancies: possible involvement of regulatory T cells in disease progression. Cancer. 2003;98:1089-1099.
    • (2003) Cancer , vol.98 , pp. 1089-1099
    • Sasada, T.1    Kimura, M.2    Yoshida, Y.3    Kanai, M.4    Takabayashi, A.5
  • 59
    • 16844378685 scopus 로고    scopus 로고
    • Increased populations of regulatory T cells in peripheral blood of patients with hepatocellular carcinoma
    • Ormandy LA, Hillemann T, Wedemeyer H, Manns MP, Greten TF, Korangy F. Increased populations of regulatory T cells in peripheral blood of patients with hepatocellular carcinoma. Cancer Res. 2005;65:2457-2464.
    • (2005) Cancer Res , vol.65 , pp. 2457-2464
    • Ormandy, L.A.1    Hillemann, T.2    Wedemeyer, H.3    Manns, M.P.4    Greten, T.F.5    Korangy, F.6
  • 60
    • 3042838753 scopus 로고    scopus 로고
    • Expression of FoxP3, a key molecule in CD4CD25 regulatory T cells, in adult T-cell leukaemia/lymphoma cells
    • Karube K, Ohshima K, Tsuchiya T, et al. Expression of FoxP3, a key molecule in CD4CD25 regulatory T cells, in adult T-cell leukaemia/lymphoma cells. Br J Haematol. 2004;126:81-84.
    • (2004) Br J Haematol , vol.126 , pp. 81-84
    • Karube, K.1    Ohshima, K.2    Tsuchiya, T.3
  • 61
    • 1442283424 scopus 로고    scopus 로고
    • Immunosuppressive regulatory T cells are abundant in the reactive lymphocytes of Hodgkin lymphoma
    • Marshall NA, Christie LE, Munro LR, et al. Immunosuppressive regulatory T cells are abundant in the reactive lymphocytes of Hodgkin lymphoma. Blood. 2004;103:1755-1762.
    • (2004) Blood , vol.103 , pp. 1755-1762
    • Marshall, N.A.1    Christie, L.E.2    Munro, L.R.3
  • 62
    • 3142737258 scopus 로고    scopus 로고
    • Foxp3 expressing CD4+CD25(high) regulatory T cells are overrepresented in human metastatic melanoma lymph nodes and inhibit the function of infiltrating T cells
    • Viguier M, Lemaitre F, Verola O, et al. Foxp3 expressing CD4+CD25(high) regulatory T cells are overrepresented in human metastatic melanoma lymph nodes and inhibit the function of infiltrating T cells. J Immunol. 2004;173:1444-1453.
    • (2004) J Immunol , vol.173 , pp. 1444-1453
    • Viguier, M.1    Lemaitre, F.2    Verola, O.3
  • 63
    • 0038155128 scopus 로고    scopus 로고
    • Association of increased levels of heavy-chain ferritin with increased CD4+ CD25+ regulatory T-cell levels in patients with melanoma
    • Gray CP, Arosio P, Hersey P. Association of increased levels of heavy-chain ferritin with increased CD4+ CD25+ regulatory T-cell levels in patients with melanoma. Clin Cancer Res. 2003;9:2551-2559.
    • (2003) Clin Cancer Res , vol.9 , pp. 2551-2559
    • Gray, C.P.1    Arosio, P.2    Hersey, P.3
  • 65
    • 0037124359 scopus 로고    scopus 로고
    • Identification of regulatory T cells in tolerated allografts
    • Graca L, Cobbold SP, Waldmann H. Identification of regulatory T cells in tolerated allografts. J Exp Med. 2002;195:1641-1646.
    • (2002) J Exp Med , vol.195 , pp. 1641-1646
    • Graca, L.1    Cobbold, S.P.2    Waldmann, H.3
  • 66
    • 15944425718 scopus 로고    scopus 로고
    • CCR6 expression defines regulatory effector/memory-like cells within the CD25(+)CD4+ T-cell subset
    • Kleinewietfeld M, Puentes F, Borsellino G, Battistini L, Rotzschke O, Falk K. CCR6 expression defines regulatory effector/memory-like cells within the CD25(+)CD4+ T-cell subset. Blood. 2005;105:2877-2886.
    • (2005) Blood , vol.105 , pp. 2877-2886
    • Kleinewietfeld, M.1    Puentes, F.2    Borsellino, G.3    Battistini, L.4    Rotzschke, O.5    Falk, K.6
  • 67
    • 0037446531 scopus 로고    scopus 로고
    • Cutting edge: Cure of colitis by CD4+CD25+ regulatory T cells
    • Mottet C, Uhlig HH, Powrie F. Cutting edge: cure of colitis by CD4+CD25+ regulatory T cells. J Immunol. 2003;170:3939-3943.
    • (2003) J Immunol , vol.170 , pp. 3939-3943
    • Mottet, C.1    Uhlig, H.H.2    Powrie, F.3
  • 68
    • 20444434616 scopus 로고    scopus 로고
    • Peripheral and intestinal regulatory CD4+ CD25(high) T cells in inflammatory bowel disease
    • Maul J, Loddenkemper C, Mundt P, et al. Peripheral and intestinal regulatory CD4+ CD25(high) T cells in inflammatory bowel disease. Gastroenterology. 2005;128:1868-1878.
    • (2005) Gastroenterology , vol.128 , pp. 1868-1878
    • Maul, J.1    Loddenkemper, C.2    Mundt, P.3
  • 69
    • 0037261145 scopus 로고    scopus 로고
    • Isolation and functional characterization of regulatory CD25brightCD4+ T cells from the target organ of patients with rheumatoid arthritis
    • Cao D, Malmstrom V, Baecher-Allan C, Hafler D, Klareskog L, Trollmo C. Isolation and functional characterization of regulatory CD25brightCD4+ T cells from the target organ of patients with rheumatoid arthritis. Eur J Immunol. 2003;33:215-223.
    • (2003) Eur J Immunol , vol.33 , pp. 215-223
    • Cao, D.1    Malmstrom, V.2    Baecher-Allan, C.3    Hafler, D.4    Klareskog, L.5    Trollmo, C.6
  • 70
    • 4444300314 scopus 로고    scopus 로고
    • CD4(+)CD25(+) regulatory T cells in rheumatoid arthritis: Differences in the presence, phenotype, and function between peripheral blood and synovial fluid
    • van Amelsfort JM, Jacobs KM, Bijlsma JW, Lafeber FP, Taams LS. CD4(+)CD25(+) regulatory T cells in rheumatoid arthritis: differences in the presence, phenotype, and function between peripheral blood and synovial fluid. Arthritis Rheum. 2004;50:2775-2785.
    • (2004) Arthritis Rheum , vol.50 , pp. 2775-2785
    • Van Amelsfort, J.M.1    Jacobs, K.M.2    Bijlsma, J.W.3    Lafeber, F.P.4    Taams, L.S.5
  • 71
    • 2942692037 scopus 로고    scopus 로고
    • CD4+CD25+ T regulatory cells dependent on ICOS promote regulation of effector cells in the prediabetic lesion
    • Herman AE, Freeman GJ, Mathis D, Benoist C. CD4+CD25+ T regulatory cells dependent on ICOS promote regulation of effector cells in the prediabetic lesion. J Exp Med. 2004;199:1479-1489.
    • (2004) J Exp Med , vol.199 , pp. 1479-1489
    • Herman, A.E.1    Freeman, G.J.2    Mathis, D.3    Benoist, C.4
  • 72
    • 0036196305 scopus 로고    scopus 로고
    • Pancreatic lymph node-derived CD4(+)CD25(+) Treg cells: Highly potent regulators of diabetes that require TRANCE-RANK signals
    • Green EA, Choi Y, Flavell RA. Pancreatic lymph node-derived CD4(+)CD25(+) Treg cells: highly potent regulators of diabetes that require TRANCE-RANK signals. Immunity. 2002;16:183-191.
    • (2002) Immunity , vol.16 , pp. 183-191
    • Green, E.A.1    Choi, Y.2    Flavell, R.A.3
  • 73
    • 1642305619 scopus 로고    scopus 로고
    • CD4+CD25+ regulatory T cells control the severity of viral immunoinflammatory lesions
    • Suvas S, Azkur AK, Kim BS, Kumaraguru U, Rouse BT. CD4+CD25+ regulatory T cells control the severity of viral immunoinflammatory lesions. J Immunol. 2004;172:4123-4132.
    • (2004) J Immunol , vol.172 , pp. 4123-4132
    • Suvas, S.1    Azkur, A.K.2    Kim, B.S.3    Kumaraguru, U.4    Rouse, B.T.5
  • 74
    • 1342324588 scopus 로고    scopus 로고
    • The pathogenesis of schistosomiasis is controlled by cooperating IL-10-producing innate effector and regulatory T cells
    • Hesse M, Piccirillo CA, Belkaid Y, et al. The pathogenesis of schistosomiasis is controlled by cooperating IL-10-producing innate effector and regulatory T cells. J Immunol. 2004;172:3157-3166.
    • (2004) J Immunol , vol.172 , pp. 3157-3166
    • Hesse, M.1    Piccirillo, C.A.2    Belkaid, Y.3
  • 75
    • 0036107373 scopus 로고    scopus 로고
    • CD25+CD4+ regulatory T cells suppress CD4+ T cell-mediated pulmonary hyperinflammation driven by Pneumocystis carinii in immunodeficient mice
    • Hori S, Carvalho TL, Demengeot J. CD25+CD4+ regulatory T cells suppress CD4+ T cell-mediated pulmonary hyperinflammation driven by Pneumocystis carinii in immunodeficient mice. Eur J Immunol. 2002;32:1282-1291.
    • (2002) Eur J Immunol , vol.32 , pp. 1282-1291
    • Hori, S.1    Carvalho, T.L.2    Demengeot, J.3
  • 76
    • 2242423605 scopus 로고    scopus 로고
    • CD4+CD25+ regulatory T cells control Leishmania major persistence and immunity
    • Belkaid Y, Piccirillo CA, Mendez S, Shevach EM, Sacks DL. CD4+CD25+ regulatory T cells control Leishmania major persistence and immunity. Nature. 2002;420:502-507.
    • (2002) Nature , vol.420 , pp. 502-507
    • Belkaid, Y.1    Piccirillo, C.A.2    Mendez, S.3    Shevach, E.M.4    Sacks, D.L.5
  • 77
    • 17044421326 scopus 로고    scopus 로고
    • Removal of regulatory T cell activity reverses hyporesponsiveness and leads to filarial parasite clearance in vivo
    • Taylor MD, LeGoff L, Harris A, Malone E, Allen JE, Maizels RM. Removal of regulatory T cell activity reverses hyporesponsiveness and leads to filarial parasite clearance in vivo. J Immunol. 2005;174:4924-4933.
    • (2005) J Immunol , vol.174 , pp. 4924-4933
    • Taylor, M.D.1    LeGoff, L.2    Harris, A.3    Malone, E.4    Allen, J.E.5    Maizels, R.M.6
  • 78
    • 26844468978 scopus 로고    scopus 로고
    • Essential role for CD103 in the T cell-mediated regulation of experimental colitis
    • Annacker O, Coombes JL, Malmstrom V, et al. Essential role for CD103 in the T cell-mediated regulation of experimental colitis. J Exp Med. 2005;202:1051-1061.
    • (2005) J Exp Med , vol.202 , pp. 1051-1061
    • Annacker, O.1    Coombes, J.L.2    Malmstrom, V.3
  • 80
    • 0037436193 scopus 로고    scopus 로고
    • Effects of interleukin-2 therapy combined with highly active antiretroviral therapy on immune restoration in HIV-1 infection: A randomized controlled trial
    • Levy Y, Durier C, Krzysiek R, et al. Effects of interleukin-2 therapy combined with highly active antiretroviral therapy on immune restoration in HIV-1 infection: a randomized controlled trial. AIDS. 2003;17:343-351.
    • (2003) AIDS , vol.17 , pp. 343-351
    • Levy, Y.1    Durier, C.2    Krzysiek, R.3
  • 81
    • 0042914703 scopus 로고    scopus 로고
    • Randomized study of high-dose and low-dose interleukin-2 in patients with metastatic renal cancer
    • Yang JC, Sherry RM, Steinberg SM, et al. Randomized study of high-dose and low-dose interleukin-2 in patients with metastatic renal cancer. J Clin Oncol. 2003;21:3127-3132.
    • (2003) J Clin Oncol , vol.21 , pp. 3127-3132
    • Yang, J.C.1    Sherry, R.M.2    Steinberg, S.M.3
  • 82
    • 3242773778 scopus 로고    scopus 로고
    • IL-2-induced CD4+ T-cell expansion in HIV-infected patients is associated with long-term decreases in T-cell proliferation
    • Sereti I, Anthony KB, Martinez-Wilson H, et al. IL-2-induced CD4+ T-cell expansion in HIV-infected patients is associated with long-term decreases in T-cell proliferation. Blood. 2004;104:775-780.
    • (2004) Blood , vol.104 , pp. 775-780
    • Sereti, I.1    Anthony, K.B.2    Martinez-Wilson, H.3
  • 83
    • 3543098686 scopus 로고    scopus 로고
    • CD25(+)CD4(+) regulatory T cells from the peripheral blood of asymptomatic HIV-infected individuals regulate CD4(+) and CD8(+) HIV-specific T cell immune responses in vitro and are associated with favorable clinical markers of disease status
    • Kinter AL, Hennessey M, Bell A, et al. CD25(+)CD4(+) regulatory T cells from the peripheral blood of asymptomatic HIV-infected individuals regulate CD4(+) and CD8(+) HIV-specific T cell immune responses in vitro and are associated with favorable clinical markers of disease status. J Exp Med. 2004;200:331-343.
    • (2004) J Exp Med , vol.200 , pp. 331-343
    • Kinter, A.L.1    Hennessey, M.2    Bell, A.3
  • 84
    • 33644784733 scopus 로고    scopus 로고
    • IL-2 administration increases CD4+CD25hiFoxp3+ regulatory T cells in cancer patients
    • Ahmadzadeh M, Rosenberg SA. IL-2 administration increases CD4+CD25hiFoxp3+ regulatory T cells in cancer patients. Blood. 2006;107:2409-2414.
    • (2006) Blood , vol.107 , pp. 2409-2414
    • Ahmadzadeh, M.1    Rosenberg, S.A.2
  • 85
    • 30744458573 scopus 로고    scopus 로고
    • Lymphopenia and interleukin-2 therapy alter homeostasis of CD4(+)CD25(+) regulatory T cells
    • Zhang H, Chua KS, Guimond M, et al. Lymphopenia and interleukin-2 therapy alter homeostasis of CD4(+)CD25(+) regulatory T cells. Nat Med. 2005;11:1238-1243.
    • (2005) Nat Med , vol.11 , pp. 1238-1243
    • Zhang, H.1    Chua, K.S.2    Guimond, M.3
  • 86
    • 4544241811 scopus 로고    scopus 로고
    • Tolerance, not immunity, crucially depends on IL-2
    • Malek TR, Bayer AL. Tolerance, not immunity, crucially depends on IL-2. Nat Rev Immunol. 2004;4:665-674.
    • (2004) Nat Rev Immunol , vol.4 , pp. 665-674
    • Malek, T.R.1    Bayer, A.L.2
  • 87
    • 15544384475 scopus 로고    scopus 로고
    • Essential role for interleukin-2 for CD4(+)CD25(+) T regulatory cell development during the neonatal period
    • Bayer AL, Yu A, Adeegbe D, Malek TR. Essential role for interleukin-2 for CD4(+)CD25(+) T regulatory cell development during the neonatal period. J Exp Med. 2005;201:769-777.
    • (2005) J Exp Med , vol.201 , pp. 769-777
    • Bayer, A.L.1    Yu, A.2    Adeegbe, D.3    Malek, T.R.4
  • 88
    • 15444374646 scopus 로고    scopus 로고
    • Homeostatic maintenance of natural Foxp3(+) CD25(+) CD4(+) regulatory T cells by interleukin (IL)-2 and induction of autoimmune disease by IL-2 neutralization
    • Setoguchi R, Hori S, Takahashi T, Sakaguchi S. Homeostatic maintenance of natural Foxp3(+) CD25(+) CD4(+) regulatory T cells by interleukin (IL)-2 and induction of autoimmune disease by IL-2 neutralization. J Exp Med. 2005;201:723-735.
    • (2005) J Exp Med , vol.201 , pp. 723-735
    • Setoguchi, R.1    Hori, S.2    Takahashi, T.3    Sakaguchi, S.4
  • 89
    • 2442637772 scopus 로고    scopus 로고
    • Cutting edge: IL-2 is critically required for the in vitro activation of CD4+CD25+ T cell suppressor function
    • Thornton AM, Donovan EE, Piccirillo CA, Shevach EM. Cutting edge: IL-2 is critically required for the in vitro activation of CD4+CD25+ T cell suppressor function. J Immunol. 2004;172:6519-6523.
    • (2004) J Immunol , vol.172 , pp. 6519-6523
    • Thornton, A.M.1    Donovan, E.E.2    Piccirillo, C.A.3    Shevach, E.M.4
  • 90
    • 0035658072 scopus 로고    scopus 로고
    • Stromal-derived factor-1 in human tumors recruits and alters the function of plasmacytoid precursor dendritic cells
    • Zou W, Machelon V, Coulomb-L'Hermin A, et al. Stromal-derived factor-1 in human tumors recruits and alters the function of plasmacytoid precursor dendritic cells. Nat Med. 2001;7:1339-1346.
    • (2001) Nat Med , vol.7 , pp. 1339-1346
    • Zou, W.1    Machelon, V.2    Coulomb-L'Hermin, A.3
  • 91
    • 19944431949 scopus 로고    scopus 로고
    • CXCL12 and vascular endothelial growth factor synergistically induce neoangiogenesis in human ovarian cancers
    • Kryczek I, Lange A, Mottram P, et al. CXCL12 and vascular endothelial growth factor synergistically induce neoangiogenesis in human ovarian cancers. Cancer Res. 2005;65:465-472.
    • (2005) Cancer Res , vol.65 , pp. 465-472
    • Kryczek, I.1    Lange, A.2    Mottram, P.3
  • 92
    • 10744226452 scopus 로고    scopus 로고
    • IL-15 enhances the in vivo antitumor activity of tumor-reactive CD8+ T cells
    • U S A
    • Klebanoff CA, Finkelstein SE, Surman DR, et al. IL-15 enhances the in vivo antitumor activity of tumor-reactive CD8+ T cells. Proc Natl Acad Sci U S A. 2004;101:1969-1974.
    • (2004) Proc Natl Acad Sci , vol.101 , pp. 1969-1974
    • Klebanoff, C.A.1    Finkelstein, S.E.2    Surman, D.R.3
  • 93
    • 19944434230 scopus 로고    scopus 로고
    • Synergy of IL-21 and IL-15 in regulating CD8+ T cell expansion and function
    • Zeng R, Spolski R, Finkelstein SE, et al. Synergy of IL-21 and IL-15 in regulating CD8+ T cell expansion and function. J Exp Med. 2005;201:139-148.
    • (2005) J Exp Med , vol.201 , pp. 139-148
    • Zeng, R.1    Spolski, R.2    Finkelstein, S.E.3
  • 94
    • 18244371047 scopus 로고    scopus 로고
    • Adjuvant IL-7 or IL-15 overcomes immunodominance and improves survival of the CD8(+) memory cell pool
    • Melchionda F, Fry TJ, Milliron MJ, et al. Adjuvant IL-7 or IL-15 overcomes immunodominance and improves survival of the CD8(+) memory cell pool. J Clin Invest. 2005;115:1177-1187.
    • (2005) J Clin Invest , vol.115 , pp. 1177-1187
    • Melchionda, F.1    Fry, T.J.2    Milliron, M.J.3
  • 95
    • 22344432319 scopus 로고    scopus 로고
    • Coexpression of CD25 and CD27 identifies FoxP3+ regulatory T cells in inflamed synovia
    • Ruprecht CR, Gattorno M, Ferlito F, et al. Coexpression of CD25 and CD27 identifies FoxP3+ regulatory T cells in inflamed synovia. J Exp Med. 2005;201:1793-1803.
    • (2005) J Exp Med , vol.201 , pp. 1793-1803
    • Ruprecht, C.R.1    Gattorno, M.2    Ferlito, F.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.