Discovery of new chemical leads for selective EP1 receptor antagonists

Bioorganic and Medicinal Chemistry

Volumn 14, Issue 16, 2006, Pages 5562-5577

  Naganawa, Atsushi ^a   Saito, Tetsuji ^a   Nagao, Yuuki ^a   Egashira, Hiromu ^a   Iwahashi, Maki ^a   Kambe, Tohru ^a   Koketsu, Masatoshi ^a   Yamamoto, Hiroshi ^a   Kobayashi, Michiyoshi ^a   Maruyama, Takayuki ^a   Ohuchida, Shuichi ^a   Nakai, Hisao ^a   Kondo, Kigen ^a   Toda, Masaaki ^a  

^a ONO PHARMACEUTICAL CO   (Japan)

Author keywords

Antagonist; EP1 receptor; Prostaglandin; Sulfonamide

Indexed keywords

[[2 [(PHENYLSULFONYL)(PROPYL)AMINO] 5 (TRIFLUOROMETHYL)PHENOXY]METHYL] BENZOIC ACID; [[2 [ISOBUTYL(PHENYLSULFONYL)AMINO] 5 (TRIFLUOROMETHYL)PHENOXY]METHYL] BENZOIC ACID; [[2 [ISOPROPYL(PHENYLSULFONYL)AMINO] 5 (TRIFLUOROMETHYL)PHENOXY]METHYL] BENZOIC ACID; BENZOIC ACID DERIVATIVE; PROSTAGLANDIN E RECEPTOR; PROSTAGLANDIN RECEPTOR BLOCKING AGENT; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BINDING AFFINITY; CONTROLLED STUDY; DRUG IDENTIFICATION; DRUG RECEPTOR BINDING; DRUG SCREENING; DRUG SELECTIVITY; FEMALE; NONHUMAN; STRUCTURE ACTIVITY RELATION;

ANALGESICS; ANIMALS; BENZOIC ACIDS; BINDING SITES; CHO CELLS; CRICETINAE; RECEPTORS, PROSTAGLANDIN E; STRUCTURE-ACTIVITY RELATIONSHIP; SULFONAMIDES;

EID: 33745610169     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2006.04.038     Document Type: Article

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