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Volumn 10, Issue 6, 2002, Pages 1743-1759
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Design and synthesis of a selective EP4-receptor agonist. Part 3: 16-phenyl-5-thiaPGE1 and 9-β-Halo derivatives with improved stability
a
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Author keywords
[No Author keywords available]
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Indexed keywords
16 (3 ETHOXYMETHYL)PHENYL OMEGA TETRANORPROSTAGLANDIN E 1;
16 (3 ETHOXYMETHYL)PHENYL OMEGA TETRANORPROSTAGLANDIN E 2;
16 (3 METHOXYMETHYL)PHENYL OMEGA TETRANORPROSTAGLANDIN E 1;
16 (3 METHOXYMETHYL)PHENYL OMEGA TETRANORPROSTAGLANDIN E 2;
16 (4 HYDROXY 3 METHYL)PHENYL OMEGA TETRANOR 5 THIAPROSTAGLANDIN E 1;
16 (4 HYDROXY 3 METHYL)PHENYL OMEGA TETRANORPROSTAGLANDIN E 1;
16 (4 HYDROXY 3 METHYL)PHENYL OMEGA TETRANORPROSTAGLANDIN E 2;
9BETA CHLORO 9 DEOXY 16 (3 ETHOXYMETHYL)PHENYL OMEGA TETRANORPROSTAGLANDIN F 2;
9BETA CHLORO 9 DEOXY 16 (3 METHOXYMETHYL)PHENYL OMEGA TETRANORPROSTAGLANDIN F 2;
DRUG DERIVATIVE;
EP4 RECEPTOR AGONIST;
KETONE;
PROSTAGLANDIN E;
PROSTAGLANDIN F;
PROTECTIVE AGENT;
UNCLASSIFIED DRUG;
CALCIUM;
CYCLIC AMP;
EP4 RECEPTOR;
PROSTAGLANDIN E RECEPTOR;
ANIMAL CELL;
ARTICLE;
CHEMICAL MODIFICATION;
CHEMICAL STRUCTURE;
CHO CELL;
CONTROLLED STUDY;
DEGRADATION;
DRUG ACTIVITY;
DRUG DESIGN;
DRUG POTENCY;
DRUG SCREENING;
DRUG SELECTIVITY;
DRUG STABILITY;
DRUG SYNTHESIS;
IN VITRO STUDY;
IN VIVO STUDY;
NONHUMAN;
STRUCTURE ACTIVITY RELATION;
ANIMAL;
CHEMISTRY;
DRUG EFFECT;
DRUG POTENTIATION;
ENZYME SPECIFICITY;
HAMSTER;
METABOLISM;
SECOND MESSENGER;
SYNTHESIS;
ANIMALS;
CALCIUM;
CHO CELLS;
CRICETINAE;
CYCLIC AMP;
DRUG DESIGN;
DRUG STABILITY;
MOLECULAR STRUCTURE;
PROSTAGLANDINS E, SYNTHETIC;
RECEPTORS, PROSTAGLANDIN E;
SECOND MESSENGER SYSTEMS;
STRUCTURE-ACTIVITY RELATIONSHIP;
SUBSTRATE SPECIFICITY;
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EID: 0036009875
PISSN: 09680896
EISSN: None
Source Type: Journal
DOI: 10.1016/S0968-0896(02)00031-7 Document Type: Article |
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Times cited : (29)
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References (16)
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