2,3-Diarylthiophenes as selective EP1 receptor antagonists

Bioorganic and Medicinal Chemistry Letters

Volumn 15, Issue 4, 2005, Pages 1155-1160

  Ducharme, Yves ^a   Blouin, Marc ^a   Carrière, Marie Claude ^a   Chateauneuf, Anne ^a   Côté, Bernard ^a   Denis, Danielle ^a   Frenette, Richard ^a   Greig, Gillian ^a   Kargman, Stacia ^a   Lamontagne, Sonia ^a   Martins, Evelyn ^a   Nantel, François ^a   O'Neill, Gary ^a   Sawyer, Nicole ^a   Metters, Kathleen M ^a   Friesen, Richard W ^a  

^a MERCK FROSST CENTRE FOR THERAPEUTIC RESEARCH   (Canada)

Author keywords

EP1 Receptor antagonist; Prostaglandin E2

Indexed keywords

PROSTAGLANDIN E RECEPTOR; PROSTAGLANDIN RECEPTOR BLOCKING AGENT; THIOPHENE DERIVATIVE;

ANIMAL EXPERIMENT; ARTICLE; BINDING AFFINITY; DRUG BINDING; DRUG DISTRIBUTION; DRUG SYNTHESIS; NONHUMAN; RAT; STATISTICAL SIGNIFICANCE; STRUCTURE ACTIVITY RELATION;

EID: 20144389545     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2004.12.005     Document Type: Article

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