Design and synthesis of a highly selective EP4-receptor agonist. Part 1: 3,7-DithiaPG derivatives with high selectivity

Bioorganic and Medicinal Chemistry Letters

Volumn 11, Issue 15, 2001, Pages 2029-2031

  Maruyama, Toru ^a   Asada, Masaki ^a   Shiraishi, Tai ^a   Ishida, Akiharu ^a   Egashira, Hiromu ^a   Yoshida, Hideyuki ^a   Maruyama, Takayuki ^a   Ohuchida, Shuichi ^a   Nakai, Hisao ^a   Kondo, Kigen ^a   Toda, Masaaki ^a  

^a ONO PHARMACEUTICAL CO   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

16 (3 ETHOXYMETHYL)PHENYL DERIVATIVE; 16 (3 METHOXYMETHYL)PHENYL DERIVATIVE; 3 METHYL DERIVATIVE; 3,7 DITHIAPROSTAGLANDIN DERIVATIVE; 7 THIAPROSTAGLANDIN DERIVATIVE; PROSTAGLANDIN RECEPTOR STIMULATING AGENT; UNCLASSIFIED DRUG;

ARTICLE; CHEMICAL MODIFICATION; DRUG ACTIVITY; DRUG DESIGN; DRUG SELECTIVITY; DRUG SYNTHESIS; STRUCTURE ACTIVITY RELATION;

ALKENES; ANIMALS; BINDING SITES; CHO CELLS; CRICETINAE; CYCLIC AMP; CYCLOPENTANES; DRUG DESIGN; HUMANS; LIGANDS; MICE; RECEPTORS, PROSTAGLANDIN E; SENSITIVITY AND SPECIFICITY; SULFUR;

EID: 0035817283     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-894X(01)00364-X     Document Type: Article

References (9)