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Volumn 8, Issue 3, 2006, Pages 206-214

Genomics and epigenomics of hypertension

Author keywords

Epigenetics; Gene expression; Genetics; Hypertension; Linkage; Single nucleotide polymorphism

Indexed keywords

11BETA HYDROXYSTEROID DEHYDROGENASE; ADENOSINE TRIPHOSPHATE SENSITIVE POTASSIUM CHANNEL; ALDOSTERONE SYNTHASE; CHLORIDE CHANNEL; DNA; MINERALOCORTICOID RECEPTOR; PROTEIN SERINE THREONINE KINASE; SODIUM CHANNEL; SODIUM POTASSIUM CHLORIDE COTRANSPORTER; STEROID 11BETA MONOOXYGENASE;

EID: 33744940566     PISSN: 14648431     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review
Times cited : (5)

References (107)
  • 1
    • 4644242120 scopus 로고    scopus 로고
    • The burden of adult hypertension in the United States 1999 to 2000: A rising tide
    • Fields LE, Burt VL, Cutler JA, Hughes J, Roccella EJ, Sorlie P: The burden of adult hypertension in the United States 1999 to 2000: A rising tide. Hypertension (2004) 44(4):398-404.
    • (2004) Hypertension , vol.44 , Issue.4 , pp. 398-404
    • Fields, L.E.1    Burt, V.L.2    Cutler, J.A.3    Hughes, J.4    Roccella, E.J.5    Sorlie, P.6
  • 2
    • 0025817650 scopus 로고
    • Blood pressure control - Special role of the kidneys and body fluids
    • Guyton AC: Blood pressure control - special role of the kidneys and body fluids. Science (1991) 252(5014):1813-1816.
    • (1991) Science , vol.252 , Issue.5014 , pp. 1813-1816
    • Guyton, A.C.1
  • 4
    • 0030716498 scopus 로고    scopus 로고
    • Shattuck lecture - Cardiovascular medicine at the turn of the millennium: Triumphs, concerns, and opportunities
    • Braunwald E: Shattuck lecture - cardiovascular medicine at the turn of the millennium: Triumphs, concerns, and opportunities. N Engl J Med (1997) 337(19):1360-1369.
    • (1997) N Engl J Med , vol.337 , Issue.19 , pp. 1360-1369
    • Braunwald, E.1
  • 5
    • 0037038224 scopus 로고    scopus 로고
    • Genomic medicine - A primer
    • Guttmacher AE, Collins FS: Genomic medicine - a primer. N Engl J Med (2002) 347(19):1512-1520.
    • (2002) N Engl J Med , vol.347 , Issue.19 , pp. 1512-1520
    • Guttmacher, A.E.1    Collins, F.S.2
  • 8
    • 79959503826 scopus 로고    scopus 로고
    • The International HapMap Consortium: The International HapMap Project
    • The International HapMap Consortium: The International HapMap Project. Nature (2003) 426(6968):789-796.
    • (2003) Nature , vol.426 , Issue.6968 , pp. 789-796
  • 9
    • 0002966223 scopus 로고
    • Familial aggregation and genetic epidemiology of blood pressure
    • Laragh JH, Brenner BM (Eds), Raven Press, New York, NY, USA
    • Ward R: Familial aggregation and genetic epidemiology of blood pressure. In: Hypertension: Pathophysiology, Diagnosis, and Management. Laragh JH, Brenner BM (Eds), Raven Press, New York, NY, USA (1995):67-88.
    • (1995) Hypertension: Pathophysiology, Diagnosis, and Management , pp. 67-88
    • Ward, R.1
  • 10
    • 16544382458 scopus 로고    scopus 로고
    • Dynamic relationships between the genome and exposures to environments as causes of common human diseases
    • Sing CF, Stengard JH, Kardia SL: Dynamic relationships between the genome and exposures to environments as causes of common human diseases. World Rev Nutr Diet (2004) 93:77-91.
    • (2004) World Rev Nutr Diet , vol.93 , pp. 77-91
    • Sing, C.F.1    Stengard, J.H.2    Kardia, S.L.3
  • 11
    • 0029364271 scopus 로고
    • Linear genetics, non-linear epigenetics: Complementary approaches to understanding complex diseases
    • Strohman RC: Linear genetics, non-linear epigenetics: Complementary approaches to understanding complex diseases. Integr Physiol Behav Sci (1995) 30(4):273-282.
    • (1995) Integr Physiol Behav Sci , vol.30 , Issue.4 , pp. 273-282
    • Strohman, R.C.1
  • 12
    • 0035936780 scopus 로고    scopus 로고
    • Molecular mechanisms of human hypertension
    • Lifton RP, Gharavi AG, Geller DS: Molecular mechanisms of human hypertension. Cell (2001) 104(4):545-556.
    • (2001) Cell , vol.104 , Issue.4 , pp. 545-556
    • Lifton, R.P.1    Gharavi, A.G.2    Geller, D.S.3
  • 13
    • 0037305164 scopus 로고    scopus 로고
    • Genome scans for hypertension and blood pressure regulation
    • Samani NJ: Genome scans for hypertension and blood pressure regulation. Am J Hypertens (2003) 16(2):167-171.
    • (2003) Am J Hypertens , vol.16 , Issue.2 , pp. 167-171
    • Samani, N.J.1
  • 19
    • 0037305071 scopus 로고    scopus 로고
    • Large-scale search for genes predisposing to essential hypertension
    • Lalouel JM: Large-scale search for genes predisposing to essential hypertension. Am J Hypertens (2003) 16(2):163-166.
    • (2003) Am J Hypertens , vol.16 , Issue.2 , pp. 163-166
    • Lalouel, J.M.1
  • 20
    • 4444241065 scopus 로고    scopus 로고
    • Genome scan for hypertension in nonobese African Americans: The National Heart, Lung, and Blood Institute Family Blood Pressure Program
    • Morrison AC, Cooper R, Hunt S, Lewis CE, Luke A, Mosley TH, Boerwinkle, E: Genome scan for hypertension in nonobese African Americans: The National Heart, Lung, and Blood Institute Family Blood Pressure Program. Am J Hypertens (2004) 17(9):834-838.
    • (2004) Am J Hypertens , vol.17 , Issue.9 , pp. 834-838
    • Morrison, A.C.1    Cooper, R.2    Hunt, S.3    Lewis, C.E.4    Luke, A.5    Mosley, T.H.6    Boerwinkle, E.7
  • 23
    • 0027375377 scopus 로고
    • Renin profiling for diagnosis, risk assessment, and treatment of hypertension
    • Laragh JH: Renin profiling for diagnosis, risk assessment, and treatment of hypertension. Kidney Int (1993) 44(5):1163-1175.
    • (1993) Kidney Int , vol.44 , Issue.5 , pp. 1163-1175
    • Laragh, J.H.1
  • 24
    • 0032127081 scopus 로고    scopus 로고
    • Renin system analysis: A rational method for the diagnosis and treatment of the individual patient with hypertension
    • Blumenfeld JD, Laragh JH: Renin system analysis: A rational method for the diagnosis and treatment of the individual patient with hypertension. Am J Hypertens (1998) 11(7):894-896.
    • (1998) Am J Hypertens , vol.11 , Issue.7 , pp. 894-896
    • Blumenfeld, J.D.1    Laragh, J.H.2
  • 28
    • 0029741063 scopus 로고    scopus 로고
    • The future of genetic studies of complex human diseases
    • Risch N, Merikangas K: The future of genetic studies of complex human diseases. Science (1996) 273(5281):1516-1517.
    • (1996) Science , vol.273 , Issue.5281 , pp. 1516-1517
    • Risch, N.1    Merikangas, K.2
  • 31
    • 31944439902 scopus 로고    scopus 로고
    • WNK1 kinase polymorphism and blood pressure response to a thiazide diuretic
    • Turner ST, Schwartz GL, Chapman AB, Boerwinkle E: WNK1 kinase polymorphism and blood pressure response to a thiazide diuretic. Hypertension (2005) 46(4):758-765.
    • (2005) Hypertension , vol.46 , Issue.4 , pp. 758-765
    • Turner, S.T.1    Schwartz, G.L.2    Chapman, A.B.3    Boerwinkle, E.4
  • 32
    • 4744369165 scopus 로고    scopus 로고
    • Identification of 108 SNPs in TSC, WNK1, and WNK4 and their association with hypertension in a Japanese general population
    • Kokubo Y, Kamide K, Inamoto N, Tanaka C, Banno M, Takiuchi S, Kawano Y, Tomoike H, Miyata T: Identification of 108 SNPs in TSC, WNK1, and WNK4 and their association with hypertension in a Japanese general population. J Hum Genet (2004) 49(9):507-515.
    • (2004) J Hum Genet , vol.49 , Issue.9 , pp. 507-515
    • Kokubo, Y.1    Kamide, K.2    Inamoto, N.3    Tanaka, C.4    Banno, M.5    Takiuchi, S.6    Kawano, Y.7    Tomoike, H.8    Miyata, T.9
  • 33
    • 16844366786 scopus 로고    scopus 로고
    • Genome-wide strategies for detecting multiple loci that influence complex diseases
    • Marchini J, Donnelly P, Cardon LR: Genome-wide strategies for detecting multiple loci that influence complex diseases. Nat Genet (2005) 37(4):413-417.
    • (2005) Nat Genet , vol.37 , Issue.4 , pp. 413-417
    • Marchini, J.1    Donnelly, P.2    Cardon, L.R.3
  • 34
    • 0345411335 scopus 로고    scopus 로고
    • The ubiquitous nature of epistasis in determining susceptibility to common human diseases
    • Moore JH: The ubiquitous nature of epistasis in determining susceptibility to common human diseases. Hum Hered (2003) 56(1-3):73-82.
    • (2003) Hum Hered , vol.56 , Issue.1-3 , pp. 73-82
    • Moore, J.H.1
  • 36
    • 0034029892 scopus 로고    scopus 로고
    • Robustness against mutations in genetic networks of yeast
    • Wagner A: Robustness against mutations in genetic networks of yeast. Nat Genet (2000) 24(4):355-361.
    • (2000) Nat Genet , vol.24 , Issue.4 , pp. 355-361
    • Wagner, A.1
  • 37
    • 4344659001 scopus 로고    scopus 로고
    • Detecting epistatic interactions contributing to quantitative traits
    • Culverhouse R, Klein T, Shannon W: Detecting epistatic interactions contributing to quantitative traits. Genet Epidemiol (2004) 27(2):141-152.
    • (2004) Genet Epidemiol , vol.27 , Issue.2 , pp. 141-152
    • Culverhouse, R.1    Klein, T.2    Shannon, W.3
  • 38
    • 0034531149 scopus 로고    scopus 로고
    • Complex adaptive systems and human health: The influence of common genotypes of the apolipoprotein E (ApoE) gene polymorphism and age on the relational order within a field of lipid metabolism traits
    • Zerba KE, Ferrell RE, Sing CF: Complex adaptive systems and human health: The influence of common genotypes of the apolipoprotein E (ApoE) gene polymorphism and age on the relational order within a field of lipid metabolism traits. Hum Genet (2000) 107(5):466-475.
    • (2000) Hum Genet , vol.107 , Issue.5 , pp. 466-475
    • Zerba, K.E.1    Ferrell, R.E.2    Sing, C.F.3
  • 39
    • 7644238181 scopus 로고    scopus 로고
    • Biological robustness
    • Kitano H: Biological robustness. Nat Rev Genet (2004) 5(11):826-837.
    • (2004) Nat Rev Genet , vol.5 , Issue.11 , pp. 826-837
    • Kitano, H.1
  • 40
    • 0035830860 scopus 로고    scopus 로고
    • Principles for the buffering of genetic variation
    • Hartman JL, Garvik B, Hartwell L: Principles for the buffering of genetic variation. Science (2001) 291(5506):1001-1004.
    • (2001) Science , vol.291 , Issue.5506 , pp. 1001-1004
    • Hartman, J.L.1    Garvik, B.2    Hartwell, L.3
  • 41
    • 0842309878 scopus 로고    scopus 로고
    • Genetics Robust interactions
    • Hartwell L: Genetics. Robust interactions. Science (2004) 303(5659):774-775.
    • (2004) Science , vol.303 , Issue.5659 , pp. 774-775
    • Hartwell, L.1
  • 45
    • 0346373654 scopus 로고    scopus 로고
    • Selecting a maximally informative set of single-nucleotide polymorphisms for association analyses using linkage disequilibrium
    • Carlson CS, Eberle MA, Rieder MJ, Yi Q, Kruglyak L, Nickerson DA: Selecting a maximally informative set of single-nucleotide polymorphisms for association analyses using linkage disequilibrium. Am J Hum Genet (2004) 74(1):106-120.
    • (2004) Am J Hum Genet , vol.74 , Issue.1 , pp. 106-120
    • Carlson, C.S.1    Eberle, M.A.2    Rieder, M.J.3    Yi, Q.4    Kruglyak, L.5    Nickerson, D.A.6
  • 46
    • 0033039497 scopus 로고    scopus 로고
    • Prospects for whole-genome linkage disequilibrium mapping of common disease genes
    • Kruglyak L: Prospects for whole-genome linkage disequilibrium mapping of common disease genes. Nat Genet (1999) 22(2):139-144.
    • (1999) Nat Genet , vol.22 , Issue.2 , pp. 139-144
    • Kruglyak, L.1
  • 49
    • 33744900199 scopus 로고    scopus 로고
    • NIEHS: National Institute of Environmental Health Sciences Environmental Genome Project
    • Company Website
    • NIEHS: National Institute of Environmental Health Sciences Environmental Genome Project. Company Website http://egp.gs.washington.edu/finished_genes.html
  • 50
    • 33744946387 scopus 로고    scopus 로고
    • SeattleSNPs: SeattleSNPs Variation Discovery Resource
    • Company Website
    • SeattleSNPs: SeattleSNPs Variation Discovery Resource. Company Website http://pga.mbt.washington.edu
  • 54
    • 0036137018 scopus 로고    scopus 로고
    • Nucleotide diversity and haplotype structure of the human angiotensinogen gene in two populations
    • Nakajima T, Jorde LB, Ishigami T, Umemura S, Emi M, Lalouel JM, Inoue I: Nucleotide diversity and haplotype structure of the human angiotensinogen gene in two populations. Am J Hum Genet (2002) 70(1):108-123.
    • (2002) Am J Hum Genet , vol.70 , Issue.1 , pp. 108-123
    • Nakajima, T.1    Jorde, L.B.2    Ishigami, T.3    Umemura, S.4    Emi, M.5    Lalouel, J.M.6    Inoue, I.7
  • 60
    • 0037390308 scopus 로고    scopus 로고
    • Linkage disequilibrium patterns of the human genome across populations
    • Shifman S, Kuypers J, Kokoris M, Yakir B, Darvasi A: Linkage disequilibrium patterns of the human genome across populations. Hum Mol Genet (2003) 12(7):771-776.
    • (2003) Hum Mol Genet , vol.12 , Issue.7 , pp. 771-776
    • Shifman, S.1    Kuypers, J.2    Kokoris, M.3    Yakir, B.4    Darvasi, A.5
  • 62
    • 0035451780 scopus 로고    scopus 로고
    • On the allelic spectrum of human disease
    • Reich DE, Lander ES: On the allelic spectrum of human disease. Trends Genet (2001) 17(9):502-510.
    • (2001) Trends Genet , vol.17 , Issue.9 , pp. 502-510
    • Reich, D.E.1    Lander, E.S.2
  • 63
    • 0034892062 scopus 로고    scopus 로고
    • Complex genetic diseases: Controversy over the Croesus code
    • Wright AF, Hastie ND: Complex genetic diseases: Controversy over the Croesus code. Genome Biol (2001) 2(8):1-8.
    • (2001) Genome Biol , vol.2 , Issue.8 , pp. 1-8
    • Wright, A.F.1    Hastie, N.D.2
  • 65
    • 84984932946 scopus 로고    scopus 로고
    • Population genetics - Making sense out of sequence
    • Chakravarti A: Population genetics - making sense out of sequence. Nat Genet (1999) 21 (1 Suppl):56-60.
    • (1999) Nat Genet , vol.21 , Issue.1 SUPPL. , pp. 56-60
    • Chakravarti, A.1
  • 66
    • 0033915978 scopus 로고    scopus 로고
    • The effect of marker characteristics on the power to detect linkage disequilibrium due to single or multiple ancestral mutations
    • Sham PC, Zhao JH, Curtis D: The effect of marker characteristics on the power to detect linkage disequilibrium due to single or multiple ancestral mutations. Ann Hum Genet (2000) 64(Pt 2): 161-169.
    • (2000) Ann Hum Genet , vol.64 , Issue.PART 2 , pp. 161-169
    • Sham, P.C.1    Zhao, J.H.2    Curtis, D.3
  • 67
    • 0028940267 scopus 로고
    • Epidemiological evaluation of the use of genetics to improve the predictive value of disease risk factors
    • Khoury MJ, Wagener DK: Epidemiological evaluation of the use of genetics to improve the predictive value of disease risk factors. Am J Hum Genet (1995) 56(4):835-844.
    • (1995) Am J Hum Genet , vol.56 , Issue.4 , pp. 835-844
    • Khoury, M.J.1    Wagener, D.K.2
  • 68
    • 0035922669 scopus 로고    scopus 로고
    • Epidemiological methods for studying genes and environmental factors in complex diseases
    • Clayton D, McKeigue PM: Epidemiological methods for studying genes and environmental factors in complex diseases. Lancet (2001) 358(9290):1356-1360.
    • (2001) Lancet , vol.358 , Issue.9290 , pp. 1356-1360
    • Clayton, D.1    McKeigue, P.M.2
  • 71
    • 23044510840 scopus 로고    scopus 로고
    • The transcribed genome and the heritable basis of essential hypertension
    • Doris PA, Fomage M: The transcribed genome and the heritable basis of essential hypertension. Cardiovasc Toxicol (2005) 5(2):95-108.
    • (2005) Cardiovasc Toxicol , vol.5 , Issue.2 , pp. 95-108
    • Doris, P.A.1    Fomage, M.2
  • 72
    • 0036855185 scopus 로고    scopus 로고
    • Abundant raw material for cis-regulatory evolution in humans
    • Rockman MV, Wray GA: Abundant raw material for cis-regulatory evolution in humans. Mol Biol Evol (2002) 19(11):1991-2004.
    • (2002) Mol Biol Evol , vol.19 , Issue.11 , pp. 1991-2004
    • Rockman, M.V.1    Wray, G.A.2
  • 73
    • 3142699887 scopus 로고    scopus 로고
    • Population genetic and phylogenetic evidence for positive selection on regulatory mutations at the factor VII locus in humans
    • Hahn MW, Rockman MV, Soranzo N, Goldstein DB, Wray GA: Population genetic and phylogenetic evidence for positive selection on regulatory mutations at the factor VII locus in humans. Genetics (2004) 167(2):867-877.
    • (2004) Genetics , vol.167 , Issue.2 , pp. 867-877
    • Hahn, M.W.1    Rockman, M.V.2    Soranzo, N.3    Goldstein, D.B.4    Wray, G.A.5
  • 74
    • 0345526412 scopus 로고    scopus 로고
    • Positive selection on a human-specific transcription factor binding site regulating IL4 expression
    • Rockman MV, Hahn MW, Soranzo N, Goldstein DB, Wray GA: Positive selection on a human-specific transcription factor binding site regulating IL4 expression. Curr Biol (2003) 13(23):2118-2123.
    • (2003) Curr Biol , vol.13 , Issue.23 , pp. 2118-2123
    • Rockman, M.V.1    Hahn, M.W.2    Soranzo, N.3    Goldstein, D.B.4    Wray, G.A.5
  • 76
    • 27644482314 scopus 로고    scopus 로고
    • Mapping determinants of human gene expression by regional and genome-wide association
    • Cheung VG, Spielman RS, Ewens KG, Weber TM, Morley M, Burdick JT: Mapping determinants of human gene expression by regional and genome-wide association. Nature (2005) 437(7063):1365-1369.
    • (2005) Nature , vol.437 , Issue.7063 , pp. 1365-1369
    • Cheung, V.G.1    Spielman, R.S.2    Ewens, K.G.3    Weber, T.M.4    Morley, M.5    Burdick, J.T.6
  • 80
    • 0037372003 scopus 로고    scopus 로고
    • Epigenetic regulation of gene expression: How the genome integrates intrinsic and environmental signals
    • Jaenisch R, Bird A: Epigenetic regulation of gene expression: How the genome integrates intrinsic and environmental signals. Nat Genet (2003) 33(Suppl):245-254.
    • (2003) Nat Genet , vol.33 , Issue.SUPPL. , pp. 245-254
    • Jaenisch, R.1    Bird, A.2
  • 81
    • 0022540321 scopus 로고
    • CpG-rich islands and the function of DNA methylation
    • Bird AP: CpG-rich islands and the function of DNA methylation. Nature (1986) 321(6067):209-213.
    • (1986) Nature , vol.321 , Issue.6067 , pp. 209-213
    • Bird, A.P.1
  • 83
    • 0034015438 scopus 로고    scopus 로고
    • CpG-island methylation in aging and cancer
    • Issa JP: CpG-island methylation in aging and cancer. Curr Top Microbiol Immunol (2000) 249:101-118.
    • (2000) Curr Top Microbiol Immunol , vol.249 , pp. 101-118
    • Issa, J.P.1
  • 84
    • 0028001087 scopus 로고
    • Methylation of the oestrogen receptor CpG island links ageing and neoplasia in human colon
    • Issa JP, Ottaviano YL, Celano P, Hamilton SR, Davidson NE, Baylin SB: Methylation of the oestrogen receptor CpG island links ageing and neoplasia in human colon. Nat Genet (1994) 7(4):536-540.
    • (1994) Nat Genet , vol.7 , Issue.4 , pp. 536-540
    • Issa, J.P.1    Ottaviano, Y.L.2    Celano, P.3    Hamilton, S.R.4    Davidson, N.E.5    Baylin, S.B.6
  • 86
    • 0020638422 scopus 로고
    • DNA methylation decreases in aging but not in immortal cells
    • Wilson VL, Jones PA: DNA methylation decreases in aging but not in immortal cells. Science (1983) 220(4601):1055-1057.
    • (1983) Science , vol.220 , Issue.4601 , pp. 1055-1057
    • Wilson, V.L.1    Jones, P.A.2
  • 87
    • 0042266790 scopus 로고    scopus 로고
    • Shear stress-mediated chromatin remodeling provides molecular basis for flow-dependent regulation of gene expression
    • Illi B, Nanni S, Scopece A, Farsetti A, Biglioli P, Capogrossi MC, Gaetano C: Shear stress-mediated chromatin remodeling provides molecular basis for flow-dependent regulation of gene expression. Circ Res (2003) 93(2):156-161.
    • (2003) Circ Res , vol.93 , Issue.2 , pp. 156-161
    • Illi, B.1    Nanni, S.2    Scopece, A.3    Farsetti, A.4    Biglioli, P.5    Capogrossi, M.C.6    Gaetano, C.7
  • 89
    • 0023760499 scopus 로고
    • Syndrome of apparent mineralocorticoid excess. A defect in the cortisol-cortisone shuttle
    • Stewart PM, Corrie JE, Shackleton CH, Edwards CR: Syndrome of apparent mineralocorticoid excess. A defect in the cortisol-cortisone shuttle. J Clin Invest (1988) 82(1):340-349.
    • (1988) J Clin Invest , vol.82 , Issue.1 , pp. 340-349
    • Stewart, P.M.1    Corrie, J.E.2    Shackleton, C.H.3    Edwards, C.R.4
  • 90
    • 85047694610 scopus 로고    scopus 로고
    • Epigenetic regulation of 11 β-hydroxysteroid dehydrogenase type 2 expression
    • Alikhani-Koopaei R, Fouladkou F, Frey FJ, Frey BM: Epigenetic regulation of 11 β-hydroxysteroid dehydrogenase type 2 expression. J Clin Invest (2004) 114(8):1146-1157.
    • (2004) J Clin Invest , vol.114 , Issue.8 , pp. 1146-1157
    • Alikhani-Koopaei, R.1    Fouladkou, F.2    Frey, F.J.3    Frey, B.M.4
  • 92
    • 27544504021 scopus 로고    scopus 로고
    • Determinants of the success of whole-genome association testing
    • Clark AG, Boerwinkle E, Hixson J, Sing CF: Determinants of the success of whole-genome association testing. Genome Res (2005) 15(11):1463-1467.
    • (2005) Genome Res , vol.15 , Issue.11 , pp. 1463-1467
    • Clark, A.G.1    Boerwinkle, E.2    Hixson, J.3    Sing, C.F.4
  • 93
    • 0026580019 scopus 로고
    • A chimaeric 11 β-hydroxylase/aldosterone synthase gene causes glucocorticoid-remediable aldosteronism and human hypertension
    • Lifton RP, Dluhy RG, Powers M, Rich GM, Cook S, Ulick S, Lalouel JM: A chimaeric 11 β-hydroxylase/aldosterone synthase gene causes glucocorticoid-remediable aldosteronism and human hypertension. Nature (1992) 355(6357):262-265.
    • (1992) Nature , vol.355 , Issue.6357 , pp. 262-265
    • Lifton, R.P.1    Dluhy, R.G.2    Powers, M.3    Rich, G.M.4    Cook, S.5    Ulick, S.6    Lalouel, J.M.7
  • 94
    • 0027027764 scopus 로고
    • The molecular basis of glucocorticoid-remediable aldosteronism, a Mendelian cause of human hypertension
    • Lifton RP, Dluhy RG, Powers M, Ulick S, Lalouel JM: The molecular basis of glucocorticoid-remediable aldosteronism, a Mendelian cause of human hypertension. Trans Assoc Am Physicians (1992) 105:64-71.
    • (1992) Trans Assoc Am Physicians , vol.105 , pp. 64-71
    • Lifton, R.P.1    Dluhy, R.G.2    Powers, M.3    Ulick, S.4    Lalouel, J.M.5
  • 95
    • 0029160972 scopus 로고
    • Human hypertension caused by mutations in the kidney isozyme of 11 β-hydroxysteroid dehydrogenase
    • Mune T, Rogerson FM, Nikkila H, Agarwal AK, White PC: Human hypertension caused by mutations in the kidney isozyme of 11 β-hydroxysteroid dehydrogenase. Nat Genet (1995) 10(4):394-399.
    • (1995) Nat Genet , vol.10 , Issue.4 , pp. 394-399
    • Mune, T.1    Rogerson, F.M.2    Nikkila, H.3    Agarwal, A.K.4    White, P.C.5
  • 97
    • 0029586683 scopus 로고
    • A de novo missense mutation of the β subunit of the epithelial sodium channel causes hypertension and Liddle syndrome, identifying a proline-rich segment critical for regulation of channel activity
    • Hansson JH, Schild L, Lu Y, Wilson TA, Gautschi I, Shimkets R, Nelson-Williams C, Rossier BC, Lifton RP: A de novo missense mutation of the β subunit of the epithelial sodium channel causes hypertension and Liddle syndrome, identifying a proline-rich segment critical for regulation of channel activity. Proc Natl Acad Sci USA (1995) 92(25):11495-11499.
    • (1995) Proc Natl Acad Sci USA , vol.92 , Issue.25 , pp. 11495-11499
    • Hansson, J.H.1    Schild, L.2    Lu, Y.3    Wilson, T.A.4    Gautschi, I.5    Shimkets, R.6    Nelson-Williams, C.7    Rossier, B.C.8    Lifton, R.P.9
  • 100
    • 0030032699 scopus 로고    scopus 로고
    • Bartter's syndrome, hypokalaemic alkalosis with hypercalciuria, is caused by mutations in the Na-K-2Cl cotransporter NKCC2
    • Simon DB, Karet FE, Hamdan JM, DiPietro A, Sanjad SA, Lifton RP: Bartter's syndrome, hypokalaemic alkalosis with hypercalciuria, is caused by mutations in the Na-K-2Cl cotransporter NKCC2. Nat Genet (1996) 13(2):183-188.
    • (1996) Nat Genet , vol.13 , Issue.2 , pp. 183-188
    • Simon, D.B.1    Karet, F.E.2    Hamdan, J.M.3    DiPietro, A.4    Sanjad, S.A.5    Lifton, R.P.6
  • 105
    • 0030068042 scopus 로고    scopus 로고
    • A novel splicesite mutation in the γ subunit of the epithelial sodium channel gene in three pseudohypoaldosteronism type 1 families
    • Strautnieks SS, Thompson RJ, Gardiner RM, Chung E: A novel splicesite mutation in the γ subunit of the epithelial sodium channel gene in three pseudohypoaldosteronism type 1 families. Nat Genet (1996) 13(2):248-250.
    • (1996) Nat Genet , vol.13 , Issue.2 , pp. 248-250
    • Strautnieks, S.S.1    Thompson, R.J.2    Gardiner, R.M.3    Chung, E.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.