메뉴 건너뛰기




Volumn 411, Issue 6834, 2001, Pages 199-204

Linkage disequilibrium in the human genome

Author keywords

[No Author keywords available]

Indexed keywords

DATA REDUCTION; DISEASES; GENES; MAPPING;

EID: 0035837267     PISSN: 00280836     EISSN: None     Source Type: Journal    
DOI: 10.1038/35075590     Document Type: Article
Times cited : (1387)

References (35)
  • 1
    • 0035865322 scopus 로고    scopus 로고
    • A map of human genome sequence variation containing 1.42 million single nucleotide polymorphisms
    • Sachidanandam, R. et al. A map of human genome sequence variation containing 1.42 million single nucleotide polymorphisms. Nature 409, 928-933 (2001).
    • (2001) Nature , vol.409 , pp. 928-933
    • Sachidanandam, R.1
  • 2
    • 0033039497 scopus 로고    scopus 로고
    • Prospects for whole-genome linkage disequilibrium mapping of common disease genes
    • Kruglyak, I., Prospects for whole-genome linkage disequilibrium mapping of common disease genes. Nature Genet. 22, 139-144 (1999).
    • (1999) Nature Genet. , vol.22 , pp. 139-144
    • Kruglyak, I.1
  • 3
    • 0033646621 scopus 로고    scopus 로고
    • The extent of linkage disequilibrium in four populations with distinct demographic histories
    • Dunning, A. M. et al. The extent of linkage disequilibrium in four populations with distinct demographic histories. Am. J. Hum. Genet. 67, 1544-1554 (2000).
    • (2000) Am. J. Hum. Genet. , vol.67 , pp. 1544-1554
    • Dunning, A.M.1
  • 4
    • 0035163547 scopus 로고    scopus 로고
    • Extent and distribution of linkage disequilibrium in three genomic regions
    • Abecasis, G. R. et al. Extent and distribution of linkage disequilibrium in three genomic regions. Am. J. Hum. Genet. 68, 191-197 (2001).
    • (2001) Am. J. Hum. Genet. , vol.68 , pp. 191-197
    • Abecasis, G.R.1
  • 5
    • 0033930144 scopus 로고    scopus 로고
    • Juxtaposed regions of extensive and minimal linkage disequilibrium in human Xq25 and Xq28
    • Taillon-Miller, P. et al. Juxtaposed regions of extensive and minimal linkage disequilibrium in human Xq25 and Xq28. Nature Genet. 25, 324-328 (2000).
    • (2000) Nature Genet. , vol.25 , pp. 324-328
    • Taillon-Miller, P.1
  • 6
    • 0033592988 scopus 로고    scopus 로고
    • Genetic epidemiology of single-nucleotide polymorphisms
    • Collins, A., Lonjou, C. & Morton, N. E. Genetic epidemiology of single-nucleotide polymorphisms. Proc. Natl Acad. Sci. USA 96, 15173-15177 (1999).
    • (1999) Proc. Natl Acad. Sci. USA , vol.96 , pp. 15173-15177
    • Collins, A.1    Lonjou, C.2    Morton, N.E.3
  • 7
    • 0033926130 scopus 로고    scopus 로고
    • Linkage disequilibrium and allele-frequency distributions for 114 single-nucleotide polymorphisms in five populations
    • Goddard, K. A. B., Hopkins, P. J., Hall, J. M. & Witte, J. S. Linkage disequilibrium and allele-frequency distributions for 114 single-nucleotide polymorphisms in five populations. Am. J. Hum. Genet. 66, 216-234 (2000).
    • (2000) Am. J. Hum. Genet. , vol.66 , pp. 216-234
    • Goddard, K.A.B.1    Hopkins, P.J.2    Hall, J.M.3    Witte, J.S.4
  • 8
    • 0017481191 scopus 로고
    • Is the most frequent allele the oldest?
    • Watterson, G. A. & Guess, H. A. Is the most frequent allele the oldest? Theor. Pop. Biol. 11, 141-160 (1977).
    • (1977) Theor. Pop. Biol. , vol.11 , pp. 141-160
    • Watterson, G.A.1    Guess, H.A.2
  • 9
    • 0029805706 scopus 로고    scopus 로고
    • The new genomics: Global views of biology
    • Lander, E. S. The new genomics: global views of biology. Science 274, 536-539 (1996).
    • (1996) Science , vol.274 , pp. 536-539
    • Lander, E.S.1
  • 11
    • 0023796209 scopus 로고
    • On measures of gametic disequilibrium
    • Lewontin, R. C. On measures of gametic disequilibrium. Genetics 120, 849-852 (1988).
    • (1988) Genetics , vol.120 , pp. 849-852
    • Lewontin, R.C.1
  • 12
    • 0033786787 scopus 로고    scopus 로고
    • Linkage disequilibrium and the search for complex disease genes
    • Jorde, L. B. Linkage disequilibrium and the search for complex disease genes. Genome Res. 10, 1435-1444 (2000).
    • (2000) Genome Res. , vol.10 , pp. 1435-1444
    • Jorde, L.B.1
  • 13
    • 0003695862 scopus 로고
    • (eds Futuyma, D. J. & Antonovics, J.) Oxford Univ. Press, Oxford
    • Hudson, R. R. in Oxford Surveys in Evolutionary Biology (eds Futuyma, D. J. & Antonovics, J.) 1-44 (Oxford Univ. Press, Oxford, 1990).
    • (1990) Oxford Surveys in Evolutionary Biology , pp. 1-44
    • Hudson, R.R.1
  • 14
    • 0032231888 scopus 로고    scopus 로고
    • Haplotype structure and population genetic inferences from nucleotide-sequence variation in human lipoprotein lipase
    • Clark, A. G. et al. Haplotype structure and population genetic inferences from nucleotide-sequence variation in human lipoprotein lipase. Am. J. Hum. Genet. 63, 595-612 (1998).
    • (1998) Am. J. Hum. Genet. , vol.63 , pp. 595-612
    • Clark, A.G.1
  • 16
    • 0024209791 scopus 로고
    • Admixture as a tool for finding linked genes and detecting that difference from allelic association between loci
    • Chakraborty, R. & Weiss, K. M. Admixture as a tool for finding linked genes and detecting that difference from allelic association between loci. Proc. Natl Acad. Sci. USA 85, 9119-9123 (1988).
    • (1988) Proc. Natl Acad. Sci. USA , vol.85 , pp. 9119-9123
    • Chakraborty, R.1    Weiss, K.M.2
  • 17
    • 0033918564 scopus 로고    scopus 로고
    • The genetically isolated populations of Finland and Sardinia may not be a panacea for linkage disequilibrium mapping of common disease genes
    • Eaves, I. A. et al. The genetically isolated populations of Finland and Sardinia may not be a panacea for linkage disequilibrium mapping of common disease genes. Nature Genet. 25, 320-322 (2000).
    • (2000) Nature Genet. , vol.25 , pp. 320-322
    • Eaves, I.A.1
  • 19
    • 0029667388 scopus 로고    scopus 로고
    • Global patterns of linkage disequilibrium at the CD4 locus and modern human origins
    • Tishkoff, S. A. et al. Global patterns of linkage disequilibrium at the CD4 locus and modern human origins. Science 271, 1380-1387 (1996).
    • (1996) Science , vol.271 , pp. 1380-1387
    • Tishkoff, S.A.1
  • 20
    • 0033794922 scopus 로고    scopus 로고
    • Short tandem-repeat polymorphism/Alu haplotype variation at the PLat locus: Implications for modern human origins
    • Tishkoff, S. A. et al. Short tandem-repeat polymorphism/Alu haplotype variation at the PLAT locus: Implications for modern human origins. Am. J. Hum. Genet. 67, 901-925 (2000).
    • (2000) Am. J. Hum. Genet. , vol.67 , pp. 901-925
    • Tishkoff, S.A.1
  • 21
    • 0033941841 scopus 로고    scopus 로고
    • Haplotypes and linkage disequilibrium at the phenylalanine hydroxylase locus, PAH, in a global representation of populations
    • Kidd, J. R. et al. Haplotypes and linkage disequilibrium at the phenylalanine hydroxylase locus, PAH, in a global representation of populations. Am. J. Hum. Genet. 66, 1882-1899 (2000).
    • (2000) Am. J. Hum. Genet. , vol.66 , pp. 1882-1899
    • Kidd, J.R.1
  • 22
    • 0035166802 scopus 로고    scopus 로고
    • Worldwide genetic analysis of the CFTR region
    • Mateu, E. et al. Worldwide genetic analysis of the CFTR region. Am. J. Hum. Genet. 68, 103-117 (2001).
    • (2001) Am. J. Hum. Genet. , vol.68 , pp. 103-117
    • Mateu, E.1
  • 23
    • 0003132871 scopus 로고
    • Radiocarbon evidence for the Late glacial human recolonisation of northern Europe
    • Housley, R. A., Gamble, C. S., Street, M. & Pettitt, P. Radiocarbon evidence for the Late glacial human recolonisation of northern Europe. Proc. Prehist. Soc. 63, 25-54 (1994).
    • (1994) Proc. Prehist. Soc. , vol.63 , pp. 25-54
    • Housley, R.A.1    Gamble, C.S.2    Street, M.3    Pettitt, P.4
  • 24
    • 0033764821 scopus 로고    scopus 로고
    • Tracing European founder lineages in the Near Eastern mtDNA pool
    • Richards, M. et al. Tracing European founder lineages in the Near Eastern mtDNA pool. Am. J. Hum. Genet. 67, 1251-1276 (2000).
    • (2000) Am. J. Hum. Genet. , vol.67 , pp. 1251-1276
    • Richards, M.1
  • 25
    • 0032493379 scopus 로고    scopus 로고
    • Genetic evidence for a Paleolithic human population expansion in Africa
    • Reich, D. E. & Goldstein, D. B. Genetic evidence for a Paleolithic human population expansion in Africa. Proc. Natl Acad. Sci. USA 95, 8119-8123 (1998).
    • (1998) Proc. Natl Acad. Sci. USA , vol.95 , pp. 8119-8123
    • Reich, D.E.1    Goldstein, D.B.2
  • 26
    • 0034619822 scopus 로고    scopus 로고
    • Mitochondrial genome variation and the origin of modern humans
    • Ingman, M., Kaessmann, H., Pääbo, S. & Gyllensten, U. Mitochondrial genome variation and the origin of modern humans. Nature 408, 708-713 (2000).
    • (2000) Nature , vol.408 , pp. 708-713
    • Ingman, M.1    Kaessmann, H.2    Pääbo, S.3    Gyllensten, U.4
  • 28
    • 0032991552 scopus 로고    scopus 로고
    • Characterization of single-nucleotide polymorphisms in coding regions of human genes
    • Cargill, M. et al. Characterization of single-nucleotide polymorphisms in coding regions of human genes. Nature Genet. 22, 231-238 (1999).
    • (1999) Nature Genet. , vol.22 , pp. 231-238
    • Cargill, M.1
  • 29
    • 0030872838 scopus 로고    scopus 로고
    • PolyPhred: Automating the detection and genotyping of single nucleotide substitutions using fluorescence-based sequencing
    • Nickerson, D. B., Tobe, V. O. & Taylor, S. L. PolyPhred: automating the detection and genotyping of single nucleotide substitutions using fluorescence-based sequencing. Nucleic Acids Res. 25, 2745-2751 (1997).
    • (1997) Nucleic Acids Res. , vol.25 , pp. 2745-2751
    • Nickerson, D.B.1    Tobe, V.O.2    Taylor, S.L.3
  • 30
    • 0031734601 scopus 로고    scopus 로고
    • High level multiplex genotyping by MALDI-TOF mass spectroscopy
    • Ross, P. Hall, L., Smirnov, I. & Haff, L. High level multiplex genotyping by MALDI-TOF mass spectroscopy. Nature Biotech. 16, 1347-1351 (1998).
    • (1998) Nature Biotech. , vol.16 , pp. 1347-1351
    • Ross, P.1    Hall, L.2    Smirnov, I.3    Haff, L.4
  • 31
    • 0033058730 scopus 로고    scopus 로고
    • Fluorescence polarization in homogenous nucleic acid analysis
    • Chen, X., Levine, L. & Kwok, P. Y. Fluorescence polarization in homogenous nucleic acid analysis. Genome Res. 9, 492-498 (1999).
    • (1999) Genome Res. , vol.9 , pp. 492-498
    • Chen, X.1    Levine, L.2    Kwok, P.Y.3
  • 32
    • 17044441930 scopus 로고    scopus 로고
    • Large-scale discovery and genotyping of single-nucleotide polymorphisms in the mouse
    • Lindblad-Toh, K. et al. Large-scale discovery and genotyping of single-nucleotide polymorphisms in the mouse. Nature Genet. 24, 381-386 (2000).
    • (2000) Nature Genet. , vol.24 , pp. 381-386
    • Lindblad-Toh, K.1
  • 33
    • 0029130796 scopus 로고
    • Maximum-likelihood estimation of molecular haplotype frequencies in a diploid population
    • Excoffier, L. & Slatkin, M. Maximum-likelihood estimation of molecular haplotype frequencies in a diploid population. Mol. Biol. Evol. 12, 921-927 (1995).
    • (1995) Mol. Biol. Evol. , vol.12 , pp. 921-927
    • Excoffier, L.1    Slatkin, M.2
  • 34
    • 0032231877 scopus 로고    scopus 로고
    • Comprehensive human genetic maps: Individual and sex-specific variation in recombination
    • Broman, K. W., Murray, J. C. Sheffield, V. C., White, R. L. & Weber, J. L. Comprehensive human genetic maps: individual and sex-specific variation in recombination. Am. J. Hum. Genet. 63, 861-689 (1998).
    • (1998) Am. J. Hum. Genet. , vol.63 , pp. 861-1689
    • Broman, K.W.1    Murray, J.C.2    Sheffield, V.C.3    White, R.L.4    Weber, J.L.5
  • 35
    • 2042437650 scopus 로고    scopus 로고
    • Initial sequencing and analysis of the human genome
    • Lander, E. S. et al. Initial sequencing and analysis of the human genome. Nature 409, 860-921.
    • Nature , vol.409 , pp. 860-921
    • Lander, E.S.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.