Preconditioning doses of NMDA promote neuroprotection by enhancing neuronal excitability

Journal of Neuroscience

Volumn 26, Issue 17, 2006, Pages 4509-4518

  Soriano, Francesc X ^a   Papadia, Sofia ^a   Hofmann, Frank ^b   Hardingham, Neil R ^c   Bading, Hilmar ^b   Hardingham, Giles E ^a  

^a UNIVERSITY OF EDINBURGH   (United Kingdom)

^b UNIVERSITY OF HEIDELBERG   (Germany)

^c CARDIFF UNIVERSITY   (United Kingdom)

Author keywords

Apoptosis; Calcium Ca ; CREB; Excitability; Kinase; Neuroprotection; NMDA receptor; PI3 kinase; Signal transduction; Tolerance; Transcription

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; GLYCOGEN SYNTHASE KINASE 3BETA; N METHYL DEXTRO ASPARTIC ACID; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; SYNAPSE RECEPTOR; TRANSCRIPTION FACTOR FOXO; N METHYLASPARTIC ACID; NEUROPROTECTIVE AGENT;

ACTION POTENTIAL; ANIMAL CELL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL SURVIVAL; CONTROLLED STUDY; DOSE RESPONSE; DRUG MECHANISM; ENZYME ACTIVATION; ENZYME INHIBITION; EXCITOTOXICITY; HIPPOCAMPUS; MITOCHONDRION; NERVE CELL; NERVE EXCITABILITY; NEUROPROTECTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN TRANSPORT; RAT; SIGNAL TRANSDUCTION; ANIMAL; CELL CULTURE; DRUG EFFECT; METABOLISM; PHYSIOLOGY; PRENATAL DEVELOPMENT; SPRAGUE DAWLEY RAT; SYNAPTIC TRANSMISSION;

ACTION POTENTIALS; ANIMALS; APOPTOSIS; CELL SURVIVAL; CELLS, CULTURED; DOSE-RESPONSE RELATIONSHIP, DRUG; HIPPOCAMPUS; N-METHYLASPARTATE; NEURONS; NEUROPROTECTIVE AGENTS; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, N-METHYL-D-ASPARTATE; SYNAPTIC TRANSMISSION;

EID: 33646839766     PISSN: 02706474     EISSN: 02706474     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.0455-06.2006     Document Type: Article

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