Creb and neurodegeneration

Frontiers in Bioscience

Volumn 9, Issue , 2004, Pages 100-103

  Dragunow, Mike ^a  

^a UNIVERSITY OF AUCKLAND   (New Zealand)

Author keywords

Apoptosis; Neurogenesis; Programmed cell life; Review

Indexed keywords

CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; NEUROTOXIN; TRANSCRIPTION FACTOR;

BRAIN NERVE CELL; CELL SURVIVAL; DOWN REGULATION; NERVE DEGENERATION; NEUROPROTECTION; NONHUMAN; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; REVIEW; STROKE; UPREGULATION; ANIMAL; APOPTOSIS; HUMAN; METABOLISM; PHOSPHORYLATION; PHYSIOLOGY;

ANIMALS; APOPTOSIS; CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN; HUMANS; NERVE DEGENERATION; PHOSPHORYLATION;

EID: 2542492120     PISSN: 27686701     EISSN: 27686698     Source Type: Journal    
DOI: 10.2741/1197     Document Type: Review

References (27)

1. Dragunow M, Young D, Hughes P, MacGibbon G, Lawlor P, Singleton K, Sirimanne E, Beilharz E, and Gluckman P. Is c-jun involved in nerve cell death following status epilepticus and hypoxic-ischaemic brain injury? Molec Brain Res 18, 347-352, (1993)
2. Walton M, Sirimanne E, Williams C, Gluckman P, Dragunow M. The role of the cyclic AMP response element binding protein (CREB) in hypoxic-ischemic brain damage and repair. Molec Brain Res 43, 21-29, (1996)
3. Walton M, Woodgate A-M, Mouravlev A, Xu R, During M, Dragunow M. CREB phosphorylation promotes nerve cell survival. J Neurochem 73: 1836-1842, (1999)
4. Walton M and Dragunow M. Is CREB a key to neuronal survival? Trends Neurosci 23, 48-53, (2000)
5. Young D, Lawlor P, Leone P, Dragunow M, During M. Environmental enrichment inhibits spontaneous apoptosis, prevents seizures and is neuroprotective. Nature (Medicine) 5(4) 448-453, (1999)
6. Pons S, Trejo JL, Martinez-Morales JR, Marti E. Vitronectin regulates sonic hedgehog activity during cerebellum development through CREB phosphorylation. Development 128, 1481-1492, (2001)
7. Du K, Asahara H, Jhala US, Wagner BL, Montminy M. Characterization of a CREB gain-of-function mutant with constitutive transcriptional activity in vivo. Molec Cell Biol 20, 4320-4327, (2000)
8. Nakagawa S, Kim J-E, Malberg JE, Chen J, Steffen C, Zhang Y-Z, Nestler EJ, Duman RS. Regulation of neurogenesis in adult mouse hippocampus by cAMP and CREB. J. Neurosci 22, 3673-3682 (2002)
9. Bender RA, Lauterborn JC, Gall CM, Cariaga W, Baram TZ. Enhanced CREB phosphorylation in immature dentate gyrus cells precedes neurotrophin expression and indicates a specific role of CREB in granule cell differentiation. Eur J Neurosci 13, 679-686, (2001)
10. Grimes CA, Jope RS. CREB DNA binding activity is inhibited by GSK-3 and facilitated by lithium. J Neurochem 78, 1219-1232, (2001)
11. Son H, Kim KO, Kim JS, Chang MY, Lee SH, Lee YS. Pairing of forskolin and KCL increases differentiation of immortalized hippocampal neurons in a CREB serine 133 phosphorylation-dependent and ERK-independent manner. Neurosci Lett 308, 37-40, (2001)
12. Sung JY, Shin SW, Ahn YS, Chung KC. Basic FGF-induced activation of novel CREB kinase during the differentiation of immortalized hippocampal cells. J Biol Chem 276, 13858-13866, (2001)
13. Yang EJ, Ahn YS, Chung KC. Protein kinase Dyrkl activates CREB during neuronal differnetiation in hippocampal progenitor cells. J Biol Chem 276, 39819-39824, (2001)
14. Mantamadiotis T, Lemberger T, Bleckmann SC, Kern H, Kretz O, Martin Villalba A, Tronche F, Kellendonk C, Gau D, Kapfhammer J, Otto C, Schmid W, Schutz G. Disruption of CREB function in brain leads to neurodegeneration. Nature genetics 31, 47-54, (2002)
15. Mabuchi T, Kitagawa K, Kuwabara K, Takasawa K, Ohtsuki T, Xia Z, Storm D, Yanagihara T, Hori M, Matsumoto M. Phosphorylation of CREB in hippocampal neurons as a protective response after exposure to glutamate in vitro and ischemia in vivo. J Neurosci 21, 9204-9213, (2001)
16. Bond A, Lodge D, Hicks CA, Ward MA, O'Neill MJ. NMDA receptor antagonism, but not AMPA receptor antagonism attenuates induced ischemic tolerance in the gerbil hippocampus. Eur J. Pharmacol 380, 91-99, (1999)
17. Hardingham G.E. Fukunaga Y, Bading H. Extrasynaptic NMDARs oppose synaptic NMDARs by triggering CREB shut-off and cell death pathways. Nature Neurosci. 5, 405-414 (2002)
18. See V. & Loeffler J-P. Oxidative stress induces neuronal cell death by recruiting a protease and phosphatase gated mechanism. J. Biol. Chem. 276, 35049-35059 (2001)
19. Mbebi C, See V, Mercken L, Pradier L, Muller U, Loeffler JP. Amyloid precursor protein family-induced neuronal death is mediated by impairment of the neuroprotective calcium/calmodulin protein kinase IV-dependent signaling pathway. J. Biol. Chem. 277, 20979-20990, (2002)
20. Francois F, Godinho MJ, Grimes ML. CREB is cleaved by caspases during neural cell apoptosis. FEBS Letts 486, 281-284, (2000)
21. Stanciu M, DeFranco DB. Prolonged nuclear retention of activated ERK promotes cell death generated by oxidative toxicity or proteosomal inhibition in a neuronal cell line. J Biol Chem 277, 4010-4017, (2002)
22. Wang Z, Zhang B, Wang M, Carr BI. Persistent ERK phosphorylation negatively regulates CREB activity via recruitment of CBP to pp90rsk. J Biol Chem 278, 11138-11144, (2003)
23. Shimohata T, Nakajima T, Yamada M, Uchida C, Onodera O, Naruse S, Kimura T, Koide R, Nozaki K, Sano Y, Ishiguro H, Sakoe K, Ooshima T, Sato A, Ikeuchi T, Oyake M, Sato T, Aoyagi Y, Hozumi I, Nagatsu T, Takiyama Y, Nishizawa M, Goto J, Kanazawa I, Davidson I, Tanese N, Takahashi H, Tsuji S. Expanded polyglutamine stretches interact with TAF130, interfering with CREB-dependent transcription. Nature Genetics 26, 29-36 (2000)
24. Tanaka K, Nogawa S, Nagata E, Suzuki S, Dembo T, Kosakai A, Fukuuchi Y. Effects of blockade of voltage-sensitive calcium/sodium channles by a novel phenylpyrimidine derivative NS-7 on CREB phosphorylation in focal cerebral ischemia in the rat. Brain Res. 873, 83-93 (2000)
25. Abraham WC, Logan B Greemwood JM Dragunow M. Induction and experience-dependent consolidation of stable LTP lasting months in the hippocampus. J Neurosci 22, 9626-9634, (2002)
26. Greenwood JM, Dragunow M. Muscarinic receptor-mediated phosphorylation of CREB in human neuroblastoma cells. J Neurochem 82, 389-397, (2002)
27. Yan G-M, Lin S-Z, Irwin RP, Paul SM. Activation of muscarinic receptors blocks apoptosis in cultured cerebellar granule neurons. Molec Pharm 47, 248-257, (1995)