Development of selective inhibitors and substrate of matrix metalloproteinase-12

Journal of Biological Chemistry

Volumn 281, Issue 16, 2006, Pages 11152-11160

  Devel, Laurent ^a   Rogakos, Vassilis ^b   David, Arnaud ^a   Makaritis, Anastasios ^b   Beau, Fabrice ^a   Cuniasse, Philippe ^a   Yiotakis, Athanasios ^b   Dive, Vincent ^a  

^a DIF   (France)

^b UNIVERSITY OF ATHENS   (Greece)

Author keywords

[No Author keywords available]

Indexed keywords

BIOCHEMISTRY; BIOMEDICAL ENGINEERING; ENZYME INHIBITION; PATIENT TREATMENT;

MACROPHAGE ELASTASE; MATRIX METALLOPROTEINASES (MMPS); ORDERS OF MAGNITUDE; PHOSPHINIC PEPTIDES;

AMINO ACIDS;

GLUTAMIC ACID; LYSINE; MACROPHAGE ELASTASE; MATRIX METALLOPROTEINASE 12 INHIBITOR; MATRIX METALLOPROTEINASE INHIBITOR; THREONINE; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ANEURYSM; ARTICLE; ATHEROSCLEROSIS; DRUG ACTIVITY; DRUG POTENTIATION; DRUG SCREENING; DRUG STRUCTURE; DRUG SYNTHESIS; EMPHYSEMA; ENZYME INHIBITION; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN INTERACTION; PROTEIN MOTIF;

DRUG DESIGN; ENZYME INHIBITORS; GLUTAMIC ACID; HUMANS; KINETICS; LYSINE; MATRIX METALLOPROTEINASE 12; MATRIX METALLOPROTEINASES; METALLOENDOPEPTIDASES; MODELS, CHEMICAL; MODELS, MOLECULAR; PEPTIDE LIBRARY; PEPTIDES; PROTEIN CONFORMATION; PROTEIN STRUCTURE, TERTIARY; SUBSTRATE SPECIFICITY; THREONINE; TIME FACTORS;

EID: 33646804364     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M600222200     Document Type: Article

References (55)

1. Bode, W. (2003) Biochem. Soc. Symp. 1-14
2. Brinckerhoff, C. E., and Matrisian, L. M. (2002) Nat. Rev. Mol. Cell. Biol. 3, 207-214
3. Mott, J. D., and Werb, Z. (2004) Curr. Opin. Cell Biol. 16, 558-564
4. Egeblad, M., and Werb, Z. (2002) Nat. Rev. Cancer 2, 161-174
5. Folgueras, A. R., Pendas, A. M., Sanchez, L. M., and Lopez-Otin, C. (2004) Int. J. Dev. Biol. 48, 411-424
6. Burrage, P. S., Mix, K. S., and Brinckerhoff, C. E. (2006) Front. Biosci. 11, 529-543
7. Yong, V. W., Power, C., Forsyth, P., and Edwards, D. R. (2001) Nat. Rev. Neurosci. 2, 502-511
8. Rosenberg, G. A. (2005) Lancet 365, 1291-1293
9. Dollery, C. M., and Libby, P. (2006) Cardiovasc. Res. 69, 625-635
10. Newby, A. C. (2005) Physiol. Rev. 85, 1-31
11. Whelan, C. J. (2004) Curr. Opin. Investig. Drugs 5, 511-516
12. Daheshia, M. (2005) Curr. Med. Res. Opin. 21, 587-594
13. Mannello, F., Tonti, G., and Papa, S. (2005) Curr. Cancer Drug Targets 5, 285-298
14. Vihinen, P., Ala-aho, R., and Kahari, V. M. (2005) Curr. Cancer Drug Targets 5, 203-220
15. Tayebjee, M. H., Lip, G. Y., and MacFadyen, R. J. (2005) Curr. Med. Chem. 12, 917-925
16. Coussens, L. M., Fingleton, B., and Matrisian, L. M. (2002) Science 295, 2387-2392
17. Brown, S., Meroueh, S. O., Fridman, R., and Mobashery, S. (2004) Curr. Top. Med. Chem. 4, 1227-1238
18. Cuniasse, P., Devel, L., Makaritis, A., Beau, F., Georgiadis, D., Matziari, M., Yiotakis, A., and Dive, V. (2005) Biochimie (Paris) 87, 393-402
19. Moy, F. J., Chanda, P. K., Chen, J., Cosmi, S., Edris, W., Levin, J. I., Rush, T. S., Wilhelm, J., and Powers, R. (2002) J. Am. Chem. Soc. 124, 12658-12659
20. Bertini, I., Calderone, V., Cosenza, M., Fragai, M., Lee, Y. M., Luchinat, C., Mangani, S., Terni, B., and Turano, P. (2005) Proc. Natl. Acad. Sci. U. S. A. 102, 5334-5339
21. Engel, C. K., Pirard, B., Schimanski, S., Kirsch, R., Habermann, J., Klingler, O., Schlotte, V., Weithmann, K. U., and Wendt, K. U. (2005) Chem. Biol. 12, 181-189
22. Ikejiri, M., Bernardo, M. M., Meroueh, S. O., Brown, S., Chang, M., Fridman, R., and Mobashery, S. (2005) J. Org. Chem. 70, 5709-5712
23. Dive, V., Georgiadis, D., Matziari, M., Makaritis, A., Beau, F., Cuniasse, P., and Yiotakis, A. (2004) Cell Mol. Life Sci. 61, 2010-2019
24. Makaritis, A., Georgiadis, D., Dive, V., and Yiotakis, A. (2003) Chemistry 9, 2079-2094
25. Kannan, R., Ruff, M., Kochins, J. G., Manly, S. P., Stoll, I., El Fahime, M., Noel, A., Foidart, J. M., Rio, M. C., Dive, V., and Basset, P. (1999) Protein Expression Purif. 16, 76-83
26. Montchamp, J.-L., and Dumond, Y. R. (2001) J. Am. Chem. Soc. 123, 510-511
27. Stetter, H., and Kuhlmann, H. (1979) Synthesis 1, 29-30
28. Yiotakis, A., Vassiliou, S., Jiracek, J., and Dive, V. (1996) J. Org. Chem. 61, 6601-6605
29. Vogel, A. (1989) in Vogel's Text Book of Practical Organic Chemistry (Vogel, A, Furniss, B. S., Hannaford, A. J., Smith, P. W., Tatchell, A. R., eds) pp. 1259 and 1332-1335, John Wiley & Sons, Inc., New York
30. Tanaka, A., Terasawa, T., Hagihara, H., Sakuma, Y., Ishibe, N., Sawada, M., Takasugi, H., and Tanaka, H. (1998) Bioorg. Med. Chem. 6, 15-30
31. Vassiliou, S., Mucha, A., Cuniasse, P., Georgiadis, D., Lucet-Levannier, K., Beau, F., Kannan, R., Murphy, G., Knauper, V., Rio, M. C., Basset, P., Yiotakis, A., and Dive, V. (1999) J. Med. Chem. 42, 2610-2620
32. Mucha, A., Cuniasse, P., Kannan, R., Beau, F., Yiotakis, A., Basset, P., and Dive, V. (1998) J. Biol. Chem. 273, 2763-2768
33. Horovitz, A., and Levitzki, A. (1987) Proc. Natl. Acad. Sci. U. S. A. 84, 6654-6658
34. Brooks, B. R., Bruccoleri, R. E., Olafson, B. D., States, D. J., Swaminathan, S., and Karplus, M. (1983) J. Comput. Chem. 4, 187-217
35. MacKerell, A. D., Bashford, D., Bellott, M., Dunbrack, R. L., Evanseck, J. D., Field, M. J., Fischer, S., Gao, J., Guo, H., Ha, S., Joseph-McCarthy, D., Kucnhir, L., Kuczera, K., Lau, F. T. K., Mattos, C., Michnick, S., Ngo, T., Nguyen, D. T., Prodhom, B., Reiher, W. E., Roux, B., Schlenkrick, M., Smith, J. C., Stote, R., Straub, J., Watanabe, M., Wiorkiewicz-Kuczera, J., Yin, D., and Karplus, M. (1998) J. Phys. Chem. B 102, 3586-3616
36. Gall, A. L., Ruff, M., Kannan, R., Cuniasse, P., Yiotakis, A., Dive, V., Rio, M. C., Basset, P., and Moras, D. (2001) J. Mol. Biol. 307, 577-586
37. Frisch, M. J., Trucks, G. W., Schlegel, H. B., Scuseria, G. E., Robb, M. A., Cheeseman, J. R., Zakrzewski, V. G., Montgomery, J. A., Stratmann, R. E., Burant, J. C., Dapprich, S., Millam, J. M., Daniels, A. D., Kudin, K. N., Strain, M. C., Farkas, O., Tomasi, J., Barone, V., Cossi, M., Cammi, R., Mennucci, B., Pomelli, C., Adamo, C., Clifford, S., Ochterski, J., Petersson, G. A., Ayala, P. Y., Cui, Q., Morokuma, K., Salvador, P., Dannenberg, J. J., Malick, D. K., Rabuck, A. D., Raghavachari, K., Foresman, J. B., Cioslowski, J., Ortiz, J. V., Baboul, A. G., Stefanov, B. B., Liu, G., Liashenko, A., Piskorz, P., Komaromi, R., Gomperts, R., Martin, R. L., Fox, D. J., Keith, T., Al-Laham, M. A., Peng, C. Y., Nanayakkara, A., Challacombe, M., Gill, P. M. W., Johnson, B., Chen, W., Wong, M. W., Andres, J. L., Gonzalez, C., Head-Gordon, M., Replogle, E. S., and Pople, J. A. (2002) Gaussian 98 (Revision A. 11.3), Gaussian Inc., Pittsburgh, PA
38. Knight, C. G., Willenbrock, F., and Murphy, G. (1992) FEBS Lett. 296, 263-266
39. Saghatelian, A., Jessani, N., Joseph, A., Humphrey, M., and Cravatt, B. F. (2004) Proc. Natl. Acad. Sci. U. S. A. 101, 10000-10005
40. Welch, A. R., Holman, C. M., Huber, M., Brenner, M. C., Browner, M. F., and Van Wart, H. E. (1996) Biochemistry 35, 10103-10109
41. Butler, G. S., Tam, E. M., and Overall, C. M. (2004) J. Biol. Chem. 279, 15615-15620
42. Cook, G. R., Manivannan, E., Underdahl, T., Lukacova, V., Zhang, Y., and Balaz, S. (2004) Bioorg. Med. Chem. Lett. 14, 4935-4939
43. Morales, R., Perrier, S., Florent, J. M., Beltra, J., Dufour, S., De Mendez, I., Manceau, P., Tertre, A., Moreau, F., Compere, D., Dublanchet, A. C., and O'Gara, M. (2004) J. Mol. Biol. 341, 1063-1076
44. Dublanchet, A. C., Ducrot, P., Andrianjara, C., O'Gara, M., Morales, R., Compere, D., Denis, A., Blais, S., Cluzeau, P., Courte, K., Hamon, J., Moreau, F., Prunet, M. L., and Tertre, A. (2005) Bioorg. Med. Chem. Lett. 15, 3787-3790
45. Hautamaki, R. D., Kobayashi, D. K., Senior, R. M., and Shapiro, S. D. (1997) Science 277, 2002-2004
46. Morris, D. G., Huang, X., Kaminski, N., Wang, Y., Shapiro, S. D., Dolganov, G., Glick, A., and Sheppard, D. (2003) Nature 422, 169-173
47. Wang, X., Inoue, S., Gu, J., Miyoshi, E., Noda, K., Li, W., Mizuno-Horikawa, Y., Nakano, M., Asahi, M., Takahashi, M., Uozumi, N., Ihara, S., Lee, S. H., Ikeda, Y., Yamaguchi, Y., Aze, Y., Tomiyama, Y., Fujii, J., Suzuki, K., Kondo, A., Shapiro, S. D., Lopez-Otin, C., Kuwaki, T., Okabe, M., Honke, K., and Taniguchi, N. (2005) Proc. Natl. Acad. Sci. U. S. A. 102, 15791-15796
48. Luttun, A., Lutgens, E., Manderveld, A., Maris, K., Collen, D., Carmeliet, P., and Moons, L. (2004) Circulation 109, 1408-1414
49. Morgan, A. R., Rerkasem, K., Gallagher, P. J., Zhang, B., Morris, G. E., Calder, P. C., Grimble, R. F., Eriksson, P., McPheat, W. L., Shearman, C. P., and Ye, S. (2004) Stroke 35, 1310-1315
50. Johnson, J. L., George, S. J., Newby, A. C., and Jackson, C. L. (2005) Proc. Natl. Acad. Sci. U. S. A. 102, 15575-15580
51. Curci, J. A., Liao, S., Huffman, M. D., Shapiro, S. D., and Thompson, R. W. (1998) J. Clin. Invest. 102, 1900-1910
52. Longo, G. M., Buda, S. J., Fiotta, N., Xiong, W., Griener, T., Shapiro, S., and Baxter, B. T. (2005) Surgery 137, 457-462
53. Cornelius, L. A., Nehring, L. C., Harding, E., Bolanowski, M., Welgus, H. G., Kobayashi, D. K., Pierce, R. A., and Shapiro, S. D. (1998) J. Immunol. 161, 6845- 6852
54. Hofmann, H. S., Hansen, G., Richter, G., Taege, C., Simm, A., Silber, R. E., and Burdach, S. (2005) Clin. Cancer Res. 11, 1086-1092
55. Kerkela, E., Bohling, T., Herva, R., Uria, J. A., and Saarialho-Kere, U. (2001) Bone 29, 487-493