Understanding the P1' specificity of the matrix metalloproteinases: Effect of S1' pocket mutations in matrilysin and stromelysin-1

Biochemistry

Volumn 35, Issue 31, 1996, Pages 10103-10109

  Welch, Anthony R ^a,b   Holman, Christopher M ^a   Huber, Martin ^a   Brenner, Mitchell C ^a   Browner, Michelle F ^a   Van Wart, Harold E ^a  

^a ROCHE BIOSCIENCE   (United States)

^b Diagnon Corporation   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COLLAGENASE; MATRILYSIN; STROMELYSIN; METALLOPROTEINASE; OLIGODEOXYRIBONUCLEOTIDE; RECOMBINANT PROTEIN;

AMINO ACID SUBSTITUTION; ARTICLE; ENZYME ACTIVITY; ENZYME ANALYSIS; ENZYME BINDING; ENZYME KINETICS; ENZYME SPECIFICITY; ENZYME STRUCTURE; HYDROPHOBICITY; PRIORITY JOURNAL; SITE DIRECTED MUTAGENESIS; X RAY ANALYSIS; AMINO ACID SEQUENCE; BINDING SITE; CHEMICAL STRUCTURE; CHEMISTRY; COMPARATIVE STUDY; ESCHERICHIA COLI; HUMAN; ISOLATION AND PURIFICATION; KINETICS; METABOLISM; MOLECULAR CLONING; MOLECULAR GENETICS; NUCLEOTIDE SEQUENCE; POINT MUTATION; SEQUENCE HOMOLOGY;

FELIS CATUS;

AMINO ACID SEQUENCE; BASE SEQUENCE; BINDING SITES; CLONING, MOLECULAR; ESCHERICHIA COLI; HUMANS; KINETICS; MATRIX METALLOPROTEINASE 3; MATRIX METALLOPROTEINASE 7; METALLOENDOPEPTIDASES; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; OLIGODEOXYRIBONUCLEOTIDES; POINT MUTATION; RECOMBINANT PROTEINS; SEQUENCE HOMOLOGY, AMINO ACID; SUBSTRATE SPECIFICITY;

EID: 0029666453     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi9601969     Document Type: Article

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