-
1
-
-
0034707047
-
The DNA damage response: Putting checkpoints in perspective
-
Zhou BB, Elledge SJ. The DNA damage response: putting checkpoints in perspective. Nature 2000;408:433-9.
-
(2000)
Nature
, vol.408
, pp. 433-439
-
-
Zhou, B.B.1
Elledge, S.J.2
-
4
-
-
0035796042
-
Homologous recombinational repair of DNA ensures mammalian chromosome stability
-
Thompson LH, Schild D. Homologous recombinational repair of DNA ensures mammalian chromosome stability. Mutat Res 2001;477:131-53.
-
(2001)
Mutat Res
, vol.477
, pp. 131-153
-
-
Thompson, L.H.1
Schild, D.2
-
5
-
-
0032530658
-
Homologous recombination and non-homologous end-joining pathways of DNA double-strand breaks
-
Takata M, Sasaki MS, Sonoda E, et al. Homologous recombination and non-homologous end-joining pathways of DNA double-strand breaks. EMBO J 1998;17:5497-508.
-
(1998)
EMBO J
, vol.17
, pp. 5497-5508
-
-
Takata, M.1
Sasaki, M.S.2
Sonoda, E.3
-
6
-
-
0026318356
-
Participation of p53 protein in the cellular response to DNA damage
-
Kastan MB, Onyekwere O, Sidransky D, Vogelstein B, Craig RW. Participation of p53 protein in the cellular response to DNA damage. Cancer Res 1991;51:6304-11.
-
(1991)
Cancer Res
, vol.51
, pp. 6304-6311
-
-
Kastan, M.B.1
Onyekwere, O.2
Sidransky, D.3
Vogelstein, B.4
Craig, R.W.5
-
7
-
-
0642317020
-
2 DNA damage checkpoint and their potential for cancer therapy
-
Meijer L, Jezequel A, Roberge M, editors. Roscoff (France): Editions "Life in Progress"
-
2 DNA damage checkpoint and their potential for cancer therapy. In: Meijer L, Jezequel A, Roberge M, editors. Prog Cell Cycle Res. Vol. 5. Roscoff (France): Editions "Life in Progress"; 2003. p. 423-30.
-
(2003)
Prog Cell Cycle Res
, vol.5
, pp. 423-430
-
-
Anderson, H.J.1
Andersen, R.J.2
Roberge, M.3
-
8
-
-
2642567204
-
DNA-dependent protein kinase inhibitors as drug candidates for the treatment of cancer
-
Kashishian A, Douangpanya H, Clark D, et al. DNA-dependent protein kinase inhibitors as drug candidates for the treatment of cancer. Mol Cancer Ther 2003;2:1257-64.
-
(2003)
Mol Cancer Ther
, vol.2
, pp. 1257-1264
-
-
Kashishian, A.1
Douangpanya, H.2
Clark, D.3
-
9
-
-
20444475018
-
DNA-dependent protein kinase is a molecular target for the development of noncytotoxic radiation-sensitizing drugs
-
Shinohara ET, Geng L, Tan J, et al. DNA-dependent protein kinase is a molecular target for the development of noncytotoxic radiation-sensitizing drugs. Cancer Res 2005;65:4987-92.
-
(2005)
Cancer Res
, vol.65
, pp. 4987-4992
-
-
Shinohara, E.T.1
Geng, L.2
Tan, J.3
-
10
-
-
0043133778
-
Autophosphorylation of the catalytic subunit of the DNA-dependent protein kinase is required for efficient end processing during DNA double-strand break repair
-
Ding Q, Reddy YVR, Wang W, et al. Autophosphorylation of the catalytic subunit of the DNA-dependent protein kinase is required for efficient end processing during DNA double-strand break repair. Mol Cell Biol 2003;23:5836-48.
-
(2003)
Mol Cell Biol
, vol.23
, pp. 5836-5848
-
-
Ding, Q.1
Reddy, Y.V.R.2
Wang, W.3
-
11
-
-
0028901034
-
Disruption of p53 function sensitizes breast cancer MCF-7 cells to cisplatin and pentoxifylline
-
Fan S, Smith ML, Rivet DJ, et al. Disruption of p53 function sensitizes breast cancer MCF-7 cells to cisplatin and pentoxifylline. Cancer Res 1995;55:1649-54.
-
(1995)
Cancer Res
, vol.55
, pp. 1649-1654
-
-
Fan, S.1
Smith, M.L.2
Rivet, D.J.3
-
12
-
-
0031060389
-
Cytotoxic peptides hemiasterlin, hemiasterlin A, hemiasterlin B. induce mitotic arrest and abnormal spindle formation
-
Anderson HJ, Coleman JE, Andersen RJ, Roberge M. Cytotoxic peptides hemiasterlin, hemiasterlin A, hemiasterlin B. induce mitotic arrest and abnormal spindle formation. Cancer Chemother Pharmacol 1997;39:223-6.
-
(1997)
Cancer Chemother Pharmacol
, vol.39
, pp. 223-226
-
-
Anderson, H.J.1
Coleman, J.E.2
Andersen, R.J.3
Roberge, M.4
-
13
-
-
17444423644
-
2 checkpoint inhibitors and identification of the structurally novel compound isogranulatimide
-
2 checkpoint inhibitors and identification of the structurally novel compound isogranulatimide. Cancer Res 1998;58:5701-6.
-
(1998)
Cancer Res
, vol.58
, pp. 5701-5706
-
-
Roberge, M.1
Berlinck, R.G.S.2
Xu, L.3
-
14
-
-
0242659422
-
2 DNA damage checkpoint and of protein kinases Chk1 and Chk2 by the marine sponge alkaloid debromohymenialdisine
-
2 DNA damage checkpoint and of protein kinases Chk1 and Chk2 by the marine sponge alkaloid debromohymenialdisine. J Biol Chem 2001;276:17914-9.
-
(2001)
J Biol Chem
, vol.276
, pp. 17914-17919
-
-
Curman, D.1
Cinel, B.2
Williams, D.E.3
-
15
-
-
0035930521
-
2 DNA damage checkpoint inhibition and antimitotic activity of 13-hydroxy-15-oxozoapatlin
-
2 DNA damage checkpoint inhibition and antimitotic activity of 13-hydroxy-15-oxozoapatlin. J Biol Chem 2001;276:48231-6.
-
(2001)
J Biol Chem
, vol.276
, pp. 48231-48236
-
-
Rundle, N.T.1
Xu, L.2
Andersen, R.J.3
Roberge, M.4
-
16
-
-
0037604826
-
Assays for cyclin-dependent kinase inhibitors
-
Buolamwini JK, Adjei AA, editors. Totowa (NJ): Humana Press, Inc.
-
Senderowicz AM, Lahusen T. Assays for cyclin-dependent kinase inhibitors. In: Buolamwini JK, Adjei AA, editors. Novel anticancer drug protocols. Vol. 85. Totowa (NJ): Humana Press, Inc.; 2003. p. 39-48.
-
(2003)
Novel Anticancer Drug Protocols
, vol.85
, pp. 39-48
-
-
Senderowicz, A.M.1
Lahusen, T.2
-
17
-
-
0033566082
-
Mammalian Chk2 is a downstream effector of the ATM-dependent DNA damage checkpoint pathway
-
Chaturvedi P, Eng WK, Zhu Y, et al. Mammalian Chk2 is a downstream effector of the ATM-dependent DNA damage checkpoint pathway. Oncogene 1999;18:4047-54.
-
(1999)
Oncogene
, vol.18
, pp. 4047-4054
-
-
Chaturvedi, P.1
Eng, W.K.2
Zhu, Y.3
-
18
-
-
0037604825
-
Identifying inhibitors or ATM and ATR kinase activities
-
Buolamwini JK, Adjei AA, editors. Totowa (NJ): Humana Press
-
Sarkaria JN. Identifying inhibitors or ATM and ATR kinase activities. In: Buolamwini JK, Adjei AA, editors. Novel anticancer drug protocols. Vol. 85. Totowa (NJ): Humana Press; 2003. p. 49-56.
-
(2003)
Novel Anticancer Drug Protocols
, vol.85
, pp. 49-56
-
-
Sarkaria, J.N.1
-
20
-
-
0033199892
-
Inhibition of ATM and ATR kinase activities by the radiosensitizing agent, caffeine
-
Sarkaria JN, Busby EC, Tibbetts RS, et al. Inhibition of ATM and ATR kinase activities by the radiosensitizing agent, caffeine. Cancer Res 1999;59:4375-82.
-
(1999)
Cancer Res
, vol.59
, pp. 4375-4382
-
-
Sarkaria, J.N.1
Busby, E.C.2
Tibbetts, R.S.3
-
21
-
-
0034616329
-
2/M DNA damage checkpoint by inhibiting ataxia-telangiectasia-mutated kinase activity
-
2/M DNA damage checkpoint by inhibiting ataxia-telangiectasia-mutated kinase activity. J Biol Chem 2000;275:10342-8.
-
(2000)
J Biol Chem
, vol.275
, pp. 10342-10348
-
-
Zhou, B.-B.S.1
Chaturvedi, P.2
Spring, K.3
-
24
-
-
0142025259
-
Interactive competition between homologous recombination and non-homologous end joining
-
Allen C, Halbrook J, Nickoloff JA. Interactive competition between homologous recombination and non-homologous end joining. Mol Cancer Res 2003;1:913-20.
-
(2003)
Mol Cancer Res
, vol.1
, pp. 913-920
-
-
Allen, C.1
Halbrook, J.2
Nickoloff, J.A.3
-
25
-
-
3843135141
-
Isoform-specific phosphoinositide 3-kinase inhibitors from an arylmorphine scaffold
-
Knight ZA, Chiang GG, Alaimo PJ, et al. Isoform-specific phosphoinositide 3-kinase inhibitors from an arylmorphine scaffold. Bioorg Med Chem 2004;12:4749-59.
-
(2004)
Bioorg Med Chem
, vol.12
, pp. 4749-4759
-
-
Knight, Z.A.1
Chiang, G.G.2
Alaimo, P.J.3
-
26
-
-
0026744250
-
Cell cycle regulation and the p53 tumor suppressor protein
-
Mercer WE. Cell cycle regulation and the p53 tumor suppressor protein. Crit Rev Eukaryot Gene Expr 1992;2:251-63.
-
(1992)
Crit Rev Eukaryot Gene Expr
, vol.2
, pp. 251-263
-
-
Mercer, W.E.1
-
27
-
-
0032189483
-
Inhibition of phosphoinositide 3-kinase related kinases by the radiosensitizing agent wortmannin
-
Sarkaria JN, Tibbetts RS, Busby EC, Kennedy AP, Hill DE, Abraham RT. Inhibition of phosphoinositide 3-kinase related kinases by the radiosensitizing agent wortmannin. Cancer Res 1998;58:4375-82.
-
(1998)
Cancer Res
, vol.58
, pp. 4375-4382
-
-
Sarkaria, J.N.1
Tibbetts, R.S.2
Busby, E.C.3
Kennedy, A.P.4
Hill, D.E.5
Abraham, R.T.6
-
28
-
-
0027203525
-
Isolation of two cell lines from a human malignant glioma specimen differing in sensitivity to radiation and chemotherapeutic drugs
-
Allalunis-Turner MJ, Barron GM, RS Day I, Dobler KD, Mirzayans R. Isolation of two cell lines from a human malignant glioma specimen differing in sensitivity to radiation and chemotherapeutic drugs. Radiat Res 1993;134:349-54.
-
(1993)
Radiat Res
, vol.134
, pp. 349-354
-
-
Allalunis-Turner, M.J.1
Barron, G.M.2
Day I, R.S.3
Dobler, K.D.4
Mirzayans, R.5
-
29
-
-
0033964753
-
Complementation of the Radiosensitive M059J Cell Line
-
Hoppe BS, Jensen RB, Kirchgessner CU. Complementation of the Radiosensitive M059J Cell Line. Radiat Res 2000;153:125-30.
-
(2000)
Radiat Res
, vol.153
, pp. 125-130
-
-
Hoppe, B.S.1
Jensen, R.B.2
Kirchgessner, C.U.3
-
30
-
-
0028937877
-
Absence of p350 subunit of DNA-activated protein kinase from a radiosensitive human cell line
-
Lees-Miller SP, Godbout R, Chan DW, et al. Absence of p350 subunit of DNA-activated protein kinase from a radiosensitive human cell line. Science 1995;267:1183-5.
-
(1995)
Science
, vol.267
, pp. 1183-1185
-
-
Lees-Miller, S.P.1
Godbout, R.2
Chan, D.W.3
-
31
-
-
0031825714
-
Lack of correlation between ATM protein expression and tumour cell radiosensitivity
-
Chan DW, Gately DP, Urban S, et al. Lack of correlation between ATM protein expression and tumour cell radiosensitivity. Int J Radiat Biol 1998;74:217-24.
-
(1998)
Int J Radiat Biol
, vol.74
, pp. 217-224
-
-
Chan, D.W.1
Gately, D.P.2
Urban, S.3
-
32
-
-
0031697988
-
Characterization of ATM expression, localization, and associated DNA-dependent protein kinase activity
-
Gately DP, Hittle JC, Chan GKT, Chen TJ. Characterization of ATM expression, localization, and associated DNA-dependent protein kinase activity. Mol Biol Cell 1998;9:2361-74.
-
(1998)
Mol Biol Cell
, vol.9
, pp. 2361-2374
-
-
Gately, D.P.1
Hittle, J.C.2
Chan, G.K.T.3
Chen, T.J.4
-
33
-
-
0036022349
-
Detection of ATM gene mutation in human glioma cell line M059J by a rapid frameshift/stop codon in yeast
-
Tsuchida R, Yamada T, Takagi M, et al. Detection of ATM gene mutation in human glioma cell line M059J by a rapid frameshift/stop codon in yeast. Radiat Res 2002;158:195-201.
-
(2002)
Radiat Res
, vol.158
, pp. 195-201
-
-
Tsuchida, R.1
Yamada, T.2
Takagi, M.3
-
34
-
-
0030614815
-
2-phase checkpoint in cells of a human cell line lacking DNA-dependent protein kinase activity
-
2-phase checkpoint in cells of a human cell line lacking DNA-dependent protein kinase activity. Radiat Res 1997;147:284-7.
-
(1997)
Radiat Res
, vol.147
, pp. 284-287
-
-
Allalunis-Turner, J.1
Barron, G.M.2
Day, R.S.3
-
35
-
-
0033819217
-
Human TP53 from the malignant glioma-derived cell lines M059J and M059K has a cancer-associated mutation in exon 8
-
Anderson CW, Allalunis-Turner MJ. Human TP53 from the malignant glioma-derived cell lines M059J and M059K has a cancer-associated mutation in exon 8. Radiat Res 2000;154:473-6.
-
(2000)
Radiat Res
, vol.154
, pp. 473-476
-
-
Anderson, C.W.1
Allalunis-Turner, M.J.2
-
36
-
-
0029585872
-
The XRCC4 gene encodes a novel protein involved in DNA double-strand break repair and V(D)J recombination
-
Li Z, Otevrel T, Gao Y, et al. The XRCC4 gene encodes a novel protein involved in DNA double-strand break repair and V(D)J recombination. Cell 1995;83:1079-89.
-
(1995)
Cell
, vol.83
, pp. 1079-1089
-
-
Li, Z.1
Otevrel, T.2
Gao, Y.3
-
37
-
-
0028960511
-
Defective DNA-dependent protein kinase activity is linked to V(D)J recombination and DNA repair defects associated with the murine scid mutation
-
Blunt T, Finnie NJ, Taccioli GE, et al. Defective DNA-dependent protein kinase activity is linked to V(D)J recombination and DNA repair defects associated with the murine scid mutation. Cell 1995;80:813-23.
-
(1995)
Cell
, vol.80
, pp. 813-823
-
-
Blunt, T.1
Finnie, N.J.2
Taccioli, G.E.3
-
38
-
-
1942538492
-
ATM and DNA-PK function redundantly to phosphorylate H2AX after exposure to ionizing radiation
-
Stiff T, O'Driscoll M, Rief N, Iwabuchi K, Lobrich M, Jeggo PA. ATM and DNA-PK function redundantly to phosphorylate H2AX after exposure to ionizing radiation. Cancer Res 2004;64:2390-6.
-
(2004)
Cancer Res
, vol.64
, pp. 2390-2396
-
-
Stiff, T.1
O'Driscoll, M.2
Rief, N.3
Iwabuchi, K.4
Lobrich, M.5
Jeggo, P.A.6
-
39
-
-
0032484084
-
Linkage of ATM to cell cycle regulation by the Chk2 protein kinase
-
Matsuoka S, Huang M, Elledge SJ. Linkage of ATM to cell cycle regulation by the Chk2 protein kinase. Science 1998;282:1893-7.
-
(1998)
Science
, vol.282
, pp. 1893-1897
-
-
Matsuoka, S.1
Huang, M.2
Elledge, S.J.3
-
40
-
-
0034967556
-
ATR-mediated checkpoint pathways regulate phosphorylation and activation of human Chk1
-
Zhao H, Piwnica-Worms H. ATR-mediated checkpoint pathways regulate phosphorylation and activation of human Chk1. Mol Cell Biol 2001;21:4129-39.
-
(2001)
Mol Cell Biol
, vol.21
, pp. 4129-4139
-
-
Zhao, H.1
Piwnica-Worms, H.2
-
43
-
-
0344441890
-
A DNA damage checkpoint response in telomere-initiated senescence
-
d' Adda di Fagagna F, Reaper PM, Clay-Farrace L, et al. A DNA damage checkpoint response in telomere-initiated senescence. Nature 2003;426:194-8.
-
(2003)
Nature
, vol.426
, pp. 194-198
-
-
Adda Di Fagagna, F.1
Reaper, P.M.2
Clay-Farrace, L.3
-
44
-
-
0035498628
-
Expression and DNA binding activity of the Ku heterodimer in bladder carcinoma
-
Stronati L, Gensabella G, Lamberti C, et al. Expression and DNA binding activity of the Ku heterodimer in bladder carcinoma. Cancer 2001;92:2484-92.
-
(2001)
Cancer
, vol.92
, pp. 2484-2492
-
-
Stronati, L.1
Gensabella, G.2
Lamberti, C.3
-
45
-
-
0034538205
-
Expression of Ku70 correlates with survival in carcinoma of the cervix
-
Wilson CR, Davidson SE, Margison GP, Hendry SPJH, West CM. Expression of Ku70 correlates with survival in carcinoma of the cervix. Br J Cancer 2000;83:1702-6.
-
(2000)
Br J Cancer
, vol.83
, pp. 1702-1706
-
-
Wilson, C.R.1
Davidson, S.E.2
Margison, G.P.3
Hendry, S.P.J.H.4
West, C.M.5
-
46
-
-
0035576819
-
Decreased expression of DNA-dependent protein kinase, a DNA repair protein, during human colon carcinogenesis
-
Rigas B, Borgo S, Elhosseiny A, et al. Decreased expression of DNA-dependent protein kinase, a DNA repair protein, during human colon carcinogenesis. Cancer Res 2001;61:8381-4.
-
(2001)
Cancer Res
, vol.61
, pp. 8381-8384
-
-
Rigas, B.1
Borgo, S.2
Elhosseiny, A.3
-
47
-
-
0036322641
-
DNA-dependent protein kinase in leukaemia cells and correlation with drug sensitivity
-
Eriksson A, Lewensoh R, Larsson R, Nilsson A. DNA-dependent protein kinase in leukaemia cells and correlation with drug sensitivity. Anticancer Res 2002;22:1787-93.
-
(2002)
Anticancer Res
, vol.22
, pp. 1787-1793
-
-
Eriksson, A.1
Lewensoh, R.2
Larsson, R.3
Nilsson, A.4
-
48
-
-
0037379412
-
Expression of Ku86 confers favorable outcome of tonsillar carcinoma treated with radiotherapy
-
Friesland S, Kanter-Lewensohn L, Tell R, Munck-Wikland E, Lewensohn R, Nilsson A. Expression of Ku86 confers favorable outcome of tonsillar carcinoma treated with radiotherapy. Head Neck 2003;25:313-21.
-
(2003)
Head Neck
, vol.25
, pp. 313-321
-
-
Friesland, S.1
Kanter-Lewensohn, L.2
Tell, R.3
Munck-Wikland, E.4
Lewensohn, R.5
Nilsson, A.6
|