Targeting PDZ domain proteins for treating NMDA receptor-mediated excitotoxicity

Current Topics in Medicinal Chemistry

Volumn 6, Issue 7, 2006, Pages 711-721

  Wen, Wenyu ^a   Wang, Wenning ^a,b   Zhang, Mingjie ^a  

^a HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (Hong Kong)

^b FUDAN UNIVERSITY   (China)

Author keywords

Excitotoxicity; Neuronal nitric oxide synthase; NMDA receptor; PDZ; Protein protein interaction; PSD 95; Stroke

Indexed keywords

BAICALIN; CHINESE DRUG; GLUTAMIC ACID; HERBACEOUS AGENT; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; N METHYL DEXTRO ASPARTIC ACID RECEPTOR BLOCKING AGENT; NEURONAL NITRIC OXIDE SYNTHASE; NITRIC OXIDE; NORWOGONOSIDE; OROXYLIN A GLUCURONIDE; PDZ PROTEIN; POSTSYNAPTIC DENSITY PROTEIN 95; SCUTELLARIA BAICALENSIS EXTRACT; UNCLASSIFIED DRUG; WOGONOSIDE;

BRAIN ISCHEMIA; BREAST CANCER; CLINICAL PROTOCOL; DRUG PROTEIN BINDING; DRUG STRUCTURE; DRUG SYNTHESIS; DRUG TARGETING; ENTERITIS; EXCITOTOXICITY; FRASER SYNDROME; GENE MUTATION; HEREDITARY MOTOR SENSORY NEUROPATHY; HUMAN; NERVE CELL; NEUROPROTECTION; NONHUMAN; PROTEIN ANALYSIS; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE; RECEPTOR INTRINSIC ACTIVITY; REVIEW; SIGNAL TRANSDUCTION; STROKE; UNSPECIFIED SIDE EFFECT; USHER SYNDROME; X LINKED MENTAL RETARDATION;

ANIMALS; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MEMBRANE PROTEINS; MODELS, MOLECULAR; NITRIC OXIDE SYNTHASE TYPE I; PROTEIN CONFORMATION; RECEPTORS, N-METHYL-D-ASPARTATE; SIGNAL TRANSDUCTION;

EID: 33646568441     PISSN: 15680266     EISSN: None     Source Type: Journal    
DOI: 10.2174/156802606776894474     Document Type: Review

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