-
1
-
-
0033617522
-
Notch signaling: cell fate control and signal integration in development
-
Artavanis-Tsakonas S., Rand M.D., and Lake R.J. Notch signaling: cell fate control and signal integration in development. Science 284 (1999) 770-776
-
(1999)
Science
, vol.284
, pp. 770-776
-
-
Artavanis-Tsakonas, S.1
Rand, M.D.2
Lake, R.J.3
-
2
-
-
0030748716
-
The ins and outs of Notch signaling
-
Weinmaster G. The ins and outs of Notch signaling. Mol. Cell. Neurosci. 9 (1997) 91-102
-
(1997)
Mol. Cell. Neurosci.
, vol.9
, pp. 91-102
-
-
Weinmaster, G.1
-
3
-
-
0036304110
-
The role of Notch in promoting glial and neural stem cell fates
-
Gaiano N., and Fishell G. The role of Notch in promoting glial and neural stem cell fates. Annu. Rev. Neurosci. 25 (2002) 471-490
-
(2002)
Annu. Rev. Neurosci.
, vol.25
, pp. 471-490
-
-
Gaiano, N.1
Fishell, G.2
-
4
-
-
0032242705
-
Notch signalling and the control of cell fate choices in vertebrates
-
Lewis J. Notch signalling and the control of cell fate choices in vertebrates. Semin. Cell Dev. Biol. 9 (1998) 583-589
-
(1998)
Semin. Cell Dev. Biol.
, vol.9
, pp. 583-589
-
-
Lewis, J.1
-
5
-
-
18844414504
-
The roles of receptor and ligand endocytosis in regulating Notch signaling
-
Le Borgne R., Bardin A., and Schweisguth F. The roles of receptor and ligand endocytosis in regulating Notch signaling. Development 132 (2005) 1751-1762
-
(2005)
Development
, vol.132
, pp. 1751-1762
-
-
Le Borgne, R.1
Bardin, A.2
Schweisguth, F.3
-
6
-
-
0032923759
-
Processing of the Notch ligand Delta by the metalloprotease Kuzbanian
-
Qi H., Rand M.D., Wu X., Sestan N., Wang W., Rakic P., Xu T., and Artavanis-Tsakonas S. Processing of the Notch ligand Delta by the metalloprotease Kuzbanian. Science 283 (1999) 91-94
-
(1999)
Science
, vol.283
, pp. 91-94
-
-
Qi, H.1
Rand, M.D.2
Wu, X.3
Sestan, N.4
Wang, W.5
Rakic, P.6
Xu, T.7
Artavanis-Tsakonas, S.8
-
7
-
-
0037648484
-
Notch induced proteolysis and nuclear localization of the Delta ligand
-
Bland C.E., Kimberly P., and Rand M.D. Notch induced proteolysis and nuclear localization of the Delta ligand. J. Biol. Chem. 278 (2003) 13607-13610
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 13607-13610
-
-
Bland, C.E.1
Kimberly, P.2
Rand, M.D.3
-
8
-
-
0038610845
-
The Notch ligand Delta1 is sequentially cleaved by an ADAM protease and gamma-secretase
-
Six E., Ndiaye D., Laabi Y., Brou C., Gupta-Rossi N., Israel A., and Logeat F. The Notch ligand Delta1 is sequentially cleaved by an ADAM protease and gamma-secretase. Proc. Natl. Acad. Sci. U. S. A. 100 (2003) 7638-7643
-
(2003)
Proc. Natl. Acad. Sci. U. S. A.
, vol.100
, pp. 7638-7643
-
-
Six, E.1
Ndiaye, D.2
Laabi, Y.3
Brou, C.4
Gupta-Rossi, N.5
Israel, A.6
Logeat, F.7
-
9
-
-
0037424348
-
The Notch ligands, Delta1 and Jagged2 are substrates for Presenilin-dependent "gamma-secretase" cleavage
-
Ikeuchi T., and Sisodia S.S. The Notch ligands, Delta1 and Jagged2 are substrates for Presenilin-dependent "gamma-secretase" cleavage. J. Biol. Chem. 278 (2003) 7751-7754
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 7751-7754
-
-
Ikeuchi, T.1
Sisodia, S.S.2
-
10
-
-
0141817915
-
The Notch ligands, Jagged and Delta, are sequentially processed by alpha-secretase and Presenilin/gamma-secretase and release signaling fragments
-
LaVoie M.J., and Selkoe D.J. The Notch ligands, Jagged and Delta, are sequentially processed by alpha-secretase and Presenilin/gamma-secretase and release signaling fragments. J. Biol. Chem. 278 (2003) 34427-34437
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 34427-34437
-
-
LaVoie, M.J.1
Selkoe, D.J.2
-
11
-
-
0034051852
-
Ligand endocytosis drives receptor dissociation and activation in the Notch pathway
-
Parks A.L., Klueg K.M., Stout J.R., and Muskavitch M.A. Ligand endocytosis drives receptor dissociation and activation in the Notch pathway. Development 127 (2000) 1373-1385
-
(2000)
Development
, vol.127
, pp. 1373-1385
-
-
Parks, A.L.1
Klueg, K.M.2
Stout, J.R.3
Muskavitch, M.A.4
-
12
-
-
0038686503
-
Unequal segregation of Neuralized biases Notch activation during asymmetric cell division
-
Le Borgne R., and Schweisguth F. Unequal segregation of Neuralized biases Notch activation during asymmetric cell division. Dev. Cell 5 (2003) 139-148
-
(2003)
Dev. Cell
, vol.5
, pp. 139-148
-
-
Le Borgne, R.1
Schweisguth, F.2
-
13
-
-
0031573944
-
Requirement for dynamin during Notch signaling in Drosophila neurogenesis
-
Seugnet L., Simpson P., and Haenlin M. Requirement for dynamin during Notch signaling in Drosophila neurogenesis. Dev. Biol. 192 (1997) 585-598
-
(1997)
Dev. Biol.
, vol.192
, pp. 585-598
-
-
Seugnet, L.1
Simpson, P.2
Haenlin, M.3
-
14
-
-
0035653308
-
Neuralized encodes a peripheral membrane protein involved in Delta signaling and endocytosis
-
Pavlopoulos E., Pitsouli C., Klueg K.M., Muskavitch M.A., Moschonas N.K., and Delidakis C. Neuralized encodes a peripheral membrane protein involved in Delta signaling and endocytosis. Dev. Cell 1 (2001) 807-816
-
(2001)
Dev. Cell
, vol.1
, pp. 807-816
-
-
Pavlopoulos, E.1
Pitsouli, C.2
Klueg, K.M.3
Muskavitch, M.A.4
Moschonas, N.K.5
Delidakis, C.6
-
15
-
-
0035651380
-
Drosophila Neuralized is a ubiquitin ligase that promotes the internalization and degradation of Delta
-
Lai E.C., Deblandre G.A., Kintner C., and Rubin G.M. Drosophila Neuralized is a ubiquitin ligase that promotes the internalization and degradation of Delta. Dev. Cell 1 (2001) 783-794
-
(2001)
Dev. Cell
, vol.1
, pp. 783-794
-
-
Lai, E.C.1
Deblandre, G.A.2
Kintner, C.3
Rubin, G.M.4
-
16
-
-
0037238008
-
Mind bomb is a ubiquitin ligase that is essential for efficient activation of Notch signaling by Delta
-
Itoh M., Kim C.H., Palardy G., Oda T., Jiang Y.J., Maust D., Yeo S.Y., Lorick K., Wright G.J., Ariza-McNaughton L., Weissman A.M., Lewis J., Chandrasekharappa S.C., and Chitnis A.B. Mind bomb is a ubiquitin ligase that is essential for efficient activation of Notch signaling by Delta. Dev. Cell 4 (2003) 67-82
-
(2003)
Dev. Cell
, vol.4
, pp. 67-82
-
-
Itoh, M.1
Kim, C.H.2
Palardy, G.3
Oda, T.4
Jiang, Y.J.5
Maust, D.6
Yeo, S.Y.7
Lorick, K.8
Wright, G.J.9
Ariza-McNaughton, L.10
Weissman, A.M.11
Lewis, J.12
Chandrasekharappa, S.C.13
Chitnis, A.B.14
-
18
-
-
0034532698
-
Immobilization of Notch ligand, Delta-1 is required for induction of Notch signaling
-
Varnum-Finney B., Wu L., Yu M., Brashem-Stein C., Staats S., Flowers D., Griffin J.D., and Bernstein I.D. Immobilization of Notch ligand, Delta-1 is required for induction of Notch signaling. J. Cell Sci. 113 (2000) 4313-4318
-
(2000)
J. Cell Sci.
, vol.113
, pp. 4313-4318
-
-
Varnum-Finney, B.1
Wu, L.2
Yu, M.3
Brashem-Stein, C.4
Staats, S.5
Flowers, D.6
Griffin, J.D.7
Bernstein, I.D.8
-
19
-
-
9444297354
-
Drosophila Epsin mediates a select endocytic pathway that DSL ligands must enter to activate Notch
-
Wang W., and Struhl G. Drosophila Epsin mediates a select endocytic pathway that DSL ligands must enter to activate Notch. Development 131 (2004) 5367-5380
-
(2004)
Development
, vol.131
, pp. 5367-5380
-
-
Wang, W.1
Struhl, G.2
-
20
-
-
0041355557
-
Notch and Presenilin: regulated intramembrane proteolysis links development and degeneration
-
Selkoe D., and Kopan R. Notch and Presenilin: regulated intramembrane proteolysis links development and degeneration. Annu. Rev. Neurosci. 26 (2003) 565-597
-
(2003)
Annu. Rev. Neurosci.
, vol.26
, pp. 565-597
-
-
Selkoe, D.1
Kopan, R.2
-
21
-
-
0037087506
-
Notch: a membrane-bound transcription factor
-
Kopan R. Notch: a membrane-bound transcription factor. J. Cell Sci. 115 (2002) 1095-1097
-
(2002)
J. Cell Sci.
, vol.115
, pp. 1095-1097
-
-
Kopan, R.1
-
22
-
-
0036677928
-
Direct visualization of the gamma secretase-generated carboxyl-terminal domain of the amyloid precursor protein: association with Fe65 and translocation to the nucleus
-
Kinoshita A., Whelan C.M., Smith C.J., Berezovska O., and Hyman B.T. Direct visualization of the gamma secretase-generated carboxyl-terminal domain of the amyloid precursor protein: association with Fe65 and translocation to the nucleus. J. Neurochem. 82 (2002) 839-847
-
(2002)
J. Neurochem.
, vol.82
, pp. 839-847
-
-
Kinoshita, A.1
Whelan, C.M.2
Smith, C.J.3
Berezovska, O.4
Hyman, B.T.5
-
23
-
-
0037114010
-
Processing of beta-amyloid precursor-like protein-1 and -2 by gamma-secretase regulates transcription
-
Scheinfeld M.H., Ghersi E., Laky K., Fowlkes B.J., and D'Adamio L. Processing of beta-amyloid precursor-like protein-1 and -2 by gamma-secretase regulates transcription. J. Biol. Chem. 277 (2002) 44195-44201
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 44195-44201
-
-
Scheinfeld, M.H.1
Ghersi, E.2
Laky, K.3
Fowlkes, B.J.4
D'Adamio, L.5
-
24
-
-
0034612276
-
Use of double-stranded RNA interference in Drosophila cell lines to dissect signal transduction pathways
-
Clemens J.C., Worby C.A., Simonson-Leff N., Muda M., Maehama T., Hemmings B.A., and Dixon J.E. Use of double-stranded RNA interference in Drosophila cell lines to dissect signal transduction pathways. Proc. Natl. Acad. Sci. U. S. A. 97 (2000) 6499-6503
-
(2000)
Proc. Natl. Acad. Sci. U. S. A.
, vol.97
, pp. 6499-6503
-
-
Clemens, J.C.1
Worby, C.A.2
Simonson-Leff, N.3
Muda, M.4
Maehama, T.5
Hemmings, B.A.6
Dixon, J.E.7
-
25
-
-
0027416250
-
Implications of dynamic patterns of Delta and Notch expression for cellular interactions during Drosophila development
-
Kooh P.J., Fehon R.G., and Muskavitch M.A. Implications of dynamic patterns of Delta and Notch expression for cellular interactions during Drosophila development. Development 117 (1993) 493-507
-
(1993)
Development
, vol.117
, pp. 493-507
-
-
Kooh, P.J.1
Fehon, R.G.2
Muskavitch, M.A.3
-
26
-
-
0037224740
-
The ADAMs family of metalloproteases: multidomain proteins with multiple functions
-
Seals D.F., and Courtneidge S.A. The ADAMs family of metalloproteases: multidomain proteins with multiple functions. Genes Dev. 17 (2003) 7-30
-
(2003)
Genes Dev.
, vol.17
, pp. 7-30
-
-
Seals, D.F.1
Courtneidge, S.A.2
-
27
-
-
18344380083
-
A Presenilin-1/gamma-secretase cleavage releases the E-cadherin intracellular domain and regulates disassembly of adherens junctions
-
Marambaud P., Shioi J., Serban G., Georgakopoulos A., Sarner S., Nagy V., Baki L., Wen P., Efthimiopoulos S., Shao Z., Wisniewski T., and Robakis N.K. A Presenilin-1/gamma-secretase cleavage releases the E-cadherin intracellular domain and regulates disassembly of adherens junctions. EMBO J. 21 (2002) 1948-1956
-
(2002)
EMBO J.
, vol.21
, pp. 1948-1956
-
-
Marambaud, P.1
Shioi, J.2
Serban, G.3
Georgakopoulos, A.4
Sarner, S.5
Nagy, V.6
Baki, L.7
Wen, P.8
Efthimiopoulos, S.9
Shao, Z.10
Wisniewski, T.11
Robakis, N.K.12
-
28
-
-
0037155219
-
Presenilin-dependent gamma-secretase-like intramembrane cleavage of ErbB4
-
Lee H.J., Jung K.M., Huang Y.Z., Bennett L.B., Lee J.S., Mei L., and Kim T.W. Presenilin-dependent gamma-secretase-like intramembrane cleavage of ErbB4. J. Biol. Chem. 277 (2002) 6318-6323
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 6318-6323
-
-
Lee, H.J.1
Jung, K.M.2
Huang, Y.Z.3
Bennett, L.B.4
Lee, J.S.5
Mei, L.6
Kim, T.W.7
-
29
-
-
0035956428
-
Proteolytic release of CD44 intracellular domain and its role in the CD44 signaling pathway
-
Okamoto I., Kawano Y., Murakami D., Sasayama T., Araki N., Miki T., Wong A.J., and Saya H. Proteolytic release of CD44 intracellular domain and its role in the CD44 signaling pathway. J. Cell Biol. 155 (2001) 755-762
-
(2001)
J. Cell Biol.
, vol.155
, pp. 755-762
-
-
Okamoto, I.1
Kawano, Y.2
Murakami, D.3
Sasayama, T.4
Araki, N.5
Miki, T.6
Wong, A.J.7
Saya, H.8
-
30
-
-
1542677095
-
Syndecan 3 intramembrane proteolysis is Presenilin/gamma-secretase-dependent and modulates cytosolic signaling
-
Schulz J.G., Annaert W., Vandekerckhove J., Zimmermann P., De Strooper B., and David G. Syndecan 3 intramembrane proteolysis is Presenilin/gamma-secretase-dependent and modulates cytosolic signaling. J. Biol. Chem. 278 (2003) 48651-48657
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 48651-48657
-
-
Schulz, J.G.1
Annaert, W.2
Vandekerckhove, J.3
Zimmermann, P.4
De Strooper, B.5
David, G.6
-
31
-
-
0028466705
-
Protection against a lethal dose of endotoxin by an inhibitor of tumour necrosis factor processing
-
Mohler K.M., Sleath P.R., Fitzner J.N., Cerretti D.P., Alderson M., Kerwar S.S., Torrance D.S., Otten-Evans C., Greenstreet T., Weerawarna K., Kronheim S., Peterson M., Gerhart M., Kozlosky C., March C., and Black R. Protection against a lethal dose of endotoxin by an inhibitor of tumour necrosis factor processing. Nature 370 (1994) 218-220
-
(1994)
Nature
, vol.370
, pp. 218-220
-
-
Mohler, K.M.1
Sleath, P.R.2
Fitzner, J.N.3
Cerretti, D.P.4
Alderson, M.5
Kerwar, S.S.6
Torrance, D.S.7
Otten-Evans, C.8
Greenstreet, T.9
Weerawarna, K.10
Kronheim, S.11
Peterson, M.12
Gerhart, M.13
Kozlosky, C.14
March, C.15
Black, R.16
-
32
-
-
0031915681
-
A substrate-based difluoro ketone selectively inhibits Alzheimer's gamma-secretase activity
-
Wolfe M.S., Citron M., Diehl T.S., Xia W., Donkor I.O., and Selkoe D.J. A substrate-based difluoro ketone selectively inhibits Alzheimer's gamma-secretase activity. J. Med. Chem. 41 (1998) 6-9
-
(1998)
J. Med. Chem.
, vol.41
, pp. 6-9
-
-
Wolfe, M.S.1
Citron, M.2
Diehl, T.S.3
Xia, W.4
Donkor, I.O.5
Selkoe, D.J.6
-
33
-
-
0037200036
-
Linear non-competitive inhibition of solubilized human gamma-secretase by pepstatin A methylester, L685458 sulfonamides, and benzodiazepines
-
Tian G., Sobotka-Briner C.D., Zysk J., Liu X., Birr C., Sylvester M.A., Edwards P.D., Scott C.D., and Greenberg B.D. Linear non-competitive inhibition of solubilized human gamma-secretase by pepstatin A methylester, L685458 sulfonamides, and benzodiazepines. J. Biol. Chem. 277 (2002) 31499-31505
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 31499-31505
-
-
Tian, G.1
Sobotka-Briner, C.D.2
Zysk, J.3
Liu, X.4
Birr, C.5
Sylvester, M.A.6
Edwards, P.D.7
Scott, C.D.8
Greenberg, B.D.9
-
34
-
-
0037176727
-
A novel epsilon-cleavage within the transmembrane domain of the Alzheimer amyloid precursor protein demonstrates homology with Notch processing
-
Weidemann A., Eggert S., Reinhard F.B., Vogel M., Paliga K., Baier G., Masters C.L., Beyreuther K., and Evin G. A novel epsilon-cleavage within the transmembrane domain of the Alzheimer amyloid precursor protein demonstrates homology with Notch processing. Biochemistry 41 (2002) 2825-2835
-
(2002)
Biochemistry
, vol.41
, pp. 2825-2835
-
-
Weidemann, A.1
Eggert, S.2
Reinhard, F.B.3
Vogel, M.4
Paliga, K.5
Baier, G.6
Masters, C.L.7
Beyreuther, K.8
Evin, G.9
-
35
-
-
0027980319
-
Inhibitors of the proteasome block the degradation of most cell proteins and the generation of peptides presented on MHC class I molecules
-
Rock K.L., Gramm C., Rothstein L., Clark K., Stein R., Dick L., Hwang D., and Goldberg A.L. Inhibitors of the proteasome block the degradation of most cell proteins and the generation of peptides presented on MHC class I molecules. Cell 78 (1994) 761-771
-
(1994)
Cell
, vol.78
, pp. 761-771
-
-
Rock, K.L.1
Gramm, C.2
Rothstein, L.3
Clark, K.4
Stein, R.5
Dick, L.6
Hwang, D.7
Goldberg, A.L.8
-
36
-
-
0028091764
-
Calpain inhibitors block Ca(2+)-induced suppression of neurite outgrowth in isolated hippocampal pyramidal neurons
-
Song D.K., Malmstrom T., Kater S.B., and Mykles D.L. Calpain inhibitors block Ca(2+)-induced suppression of neurite outgrowth in isolated hippocampal pyramidal neurons. J. Neurosci. Res. 39 (1994) 474-481
-
(1994)
J. Neurosci. Res.
, vol.39
, pp. 474-481
-
-
Song, D.K.1
Malmstrom, T.2
Kater, S.B.3
Mykles, D.L.4
-
37
-
-
0029774746
-
APMA (4-aminophenylmercuric acetate) activation of stromelysin-1 involves protein interactions in addition to those with cysteine-75 in the propeptide
-
Galazka G., Windsor L.J., Birkedal-Hansen H., and Engler J.A. APMA (4-aminophenylmercuric acetate) activation of stromelysin-1 involves protein interactions in addition to those with cysteine-75 in the propeptide. Biochemistry 35 (1996) 11221-11227
-
(1996)
Biochemistry
, vol.35
, pp. 11221-11227
-
-
Galazka, G.1
Windsor, L.J.2
Birkedal-Hansen, H.3
Engler, J.A.4
-
38
-
-
0025025442
-
The cysteine switch: a principle of regulation of metalloproteinase activity with potential applicability to the entire matrix metalloproteinase gene family
-
Van Wart H.E., and Birkedal-Hansen H. The cysteine switch: a principle of regulation of metalloproteinase activity with potential applicability to the entire matrix metalloproteinase gene family. Proc. Natl. Acad. Sci. U. S. A. 87 (1990) 5578-5582
-
(1990)
Proc. Natl. Acad. Sci. U. S. A.
, vol.87
, pp. 5578-5582
-
-
Van Wart, H.E.1
Birkedal-Hansen, H.2
-
39
-
-
0001373226
-
Reactions with N-ethylmaleimide and p-mercuribenzoate
-
Riordan J.F., and Vallee B.L. Reactions with N-ethylmaleimide and p-mercuribenzoate. Methods Enzymol. 25 (1972) 449-456
-
(1972)
Methods Enzymol.
, vol.25
, pp. 449-456
-
-
Riordan, J.F.1
Vallee, B.L.2
-
40
-
-
0027484363
-
Identification of a residue in the translocation pathway of a membrane carrier
-
Yan R.T., and Maloney P.C. Identification of a residue in the translocation pathway of a membrane carrier. Cell 75 (1993) 37-44
-
(1993)
Cell
, vol.75
, pp. 37-44
-
-
Yan, R.T.1
Maloney, P.C.2
-
41
-
-
24144503375
-
Asymmetric Rab 11 endosomes regulate Delta recycling and specify cell fate in the Drosophila nervous system
-
Emery G., Hutterer A., Berdnik D., Mayer B., Wirtz-Peitz F., Gaitan M.G., and Knoblich J.A. Asymmetric Rab 11 endosomes regulate Delta recycling and specify cell fate in the Drosophila nervous system. Cell 122 (2005) 763-773
-
(2005)
Cell
, vol.122
, pp. 763-773
-
-
Emery, G.1
Hutterer, A.2
Berdnik, D.3
Mayer, B.4
Wirtz-Peitz, F.5
Gaitan, M.G.6
Knoblich, J.A.7
-
42
-
-
24144499951
-
Sec15 a component of the exocyst, promotes Notch signaling during the asymmetric division of Drosophila sensory organ precursors
-
Jafar-Nejad H., Andrews H.K., Acar M., Bayat V., Wirtz-Peitz F., Mehta S.Q., Knoblich J.A., and Bellen H.J. Sec15 a component of the exocyst, promotes Notch signaling during the asymmetric division of Drosophila sensory organ precursors. Dev. Cell 9 (2005) 351-363
-
(2005)
Dev. Cell
, vol.9
, pp. 351-363
-
-
Jafar-Nejad, H.1
Andrews, H.K.2
Acar, M.3
Bayat, V.4
Wirtz-Peitz, F.5
Mehta, S.Q.6
Knoblich, J.A.7
Bellen, H.J.8
-
43
-
-
0036777494
-
Intramembrane proteolysis controls diverse signalling pathways throughout evolution
-
Urban S., and Freeman M. Intramembrane proteolysis controls diverse signalling pathways throughout evolution. Curr. Opin. Genet. Dev. 12 (2002) 512-518
-
(2002)
Curr. Opin. Genet. Dev.
, vol.12
, pp. 512-518
-
-
Urban, S.1
Freeman, M.2
-
44
-
-
0036727125
-
Y-secretase mediated proteolysis in cell-surface-receptor signaling
-
Fortini M.E. Y-secretase mediated proteolysis in cell-surface-receptor signaling. Nat. Rev., Mol. Cell Biol. 3 (2002) 673-684
-
(2002)
Nat. Rev., Mol. Cell Biol.
, vol.3
, pp. 673-684
-
-
Fortini, M.E.1
-
45
-
-
0036007117
-
Nicastrin is required for gamma-secretase cleavage of the Drosophila Notch receptor
-
Hu Y., Ye Y., and Fortini M.E. Nicastrin is required for gamma-secretase cleavage of the Drosophila Notch receptor. Dev. Cell 2 (2002) 69-78
-
(2002)
Dev. Cell
, vol.2
, pp. 69-78
-
-
Hu, Y.1
Ye, Y.2
Fortini, M.E.3
-
46
-
-
0031701904
-
Cis-interactions between Delta and Notch modulate neurogenic signalling in Drosophila
-
Jacobsen T.L., Brennan K., Arias A.M., and Muskavitch M.A. Cis-interactions between Delta and Notch modulate neurogenic signalling in Drosophila. Development 125 (1998) 4531-4540
-
(1998)
Development
, vol.125
, pp. 4531-4540
-
-
Jacobsen, T.L.1
Brennan, K.2
Arias, A.M.3
Muskavitch, M.A.4
-
47
-
-
13444283768
-
Unidirectional Notch signaling depends on continuous cleavage of Delta
-
Sapir A., Assa-Kunik E., Tsruya R., Schejter E., and Shilo B.Z. Unidirectional Notch signaling depends on continuous cleavage of Delta. Development 132 (2005) 123-132
-
(2005)
Development
, vol.132
, pp. 123-132
-
-
Sapir, A.1
Assa-Kunik, E.2
Tsruya, R.3
Schejter, E.4
Shilo, B.Z.5
-
48
-
-
0344152227
-
Identification of new Presenilin gene mutations in early-onset familial Alzheimer disease
-
Tedde A., Nacmias B., Ciantelli M., Forleo P., Cellini E., Bagnoli S., Piccini C., Caffarra P., Ghidoni E., Paganini M., Bracco L., and Sorbi S. Identification of new Presenilin gene mutations in early-onset familial Alzheimer disease. Arch. Neurol. 60 (2003) 1541-1544
-
(2003)
Arch. Neurol.
, vol.60
, pp. 1541-1544
-
-
Tedde, A.1
Nacmias, B.2
Ciantelli, M.3
Forleo, P.4
Cellini, E.5
Bagnoli, S.6
Piccini, C.7
Caffarra, P.8
Ghidoni, E.9
Paganini, M.10
Bracco, L.11
Sorbi, S.12
-
49
-
-
0034727409
-
Mutation of the conserved N-terminal cysteine (Cys92) of human Presenilin 1 causes increased A beta42 secretion in mammalian cells but impaired Notch/lin-12 signalling in C. elegans
-
Zhang D.M., Levitan D., Yu G., Nishimura M., Chen F., Tandon A., Kawarai T., Arawaka S., Supala A., Song Y.Q., Rogaeva E., Liang Y., Holmes E., Milman P., Sato C., Zhang L., and St George-Hyslop P. Mutation of the conserved N-terminal cysteine (Cys92) of human Presenilin 1 causes increased A beta42 secretion in mammalian cells but impaired Notch/lin-12 signalling in C. elegans. NeuroReport 11 (2000) 3227-3230
-
(2000)
NeuroReport
, vol.11
, pp. 3227-3230
-
-
Zhang, D.M.1
Levitan, D.2
Yu, G.3
Nishimura, M.4
Chen, F.5
Tandon, A.6
Kawarai, T.7
Arawaka, S.8
Supala, A.9
Song, Y.Q.10
Rogaeva, E.11
Liang, Y.12
Holmes, E.13
Milman, P.14
Sato, C.15
Zhang, L.16
St George-Hyslop, P.17
-
50
-
-
0036565893
-
Identification of a novel family of Presenilin homologues
-
Ponting C.P., Hutton M., Nyborg A., Baker M., Jansen K., and Golde T.E. Identification of a novel family of Presenilin homologues. Hum. Mol. Genet. 11 (2002) 1037-1044
-
(2002)
Hum. Mol. Genet.
, vol.11
, pp. 1037-1044
-
-
Ponting, C.P.1
Hutton, M.2
Nyborg, A.3
Baker, M.4
Jansen, K.5
Golde, T.E.6
-
51
-
-
0042839502
-
Organic mercury compounds: human exposure and its relevance to public health
-
Risher J.F., Murray H.E., and Prince G.R. Organic mercury compounds: human exposure and its relevance to public health. Toxicol. Ind. Health 18 (2002) 109-160
-
(2002)
Toxicol. Ind. Health
, vol.18
, pp. 109-160
-
-
Risher, J.F.1
Murray, H.E.2
Prince, G.R.3
-
53
-
-
0142213730
-
The toxicology of mercury-current exposures and clinical manifestations
-
Clarkson T.W., Magos L., and Myers G.J. The toxicology of mercury-current exposures and clinical manifestations. N. Engl. J. Med. 349 (2003) 1731-1737
-
(2003)
N. Engl. J. Med.
, vol.349
, pp. 1731-1737
-
-
Clarkson, T.W.1
Magos, L.2
Myers, G.J.3
-
54
-
-
18644367748
-
Presenilins mediate a dual intramembranous gamma-secretase cleavage of Notch-1
-
Okochi M., Steiner H., Fukumori A., Tanii H., Tomita T., Tanaka T., Iwatsubo T., Kudo T., Takeda M., and Haass C. Presenilins mediate a dual intramembranous gamma-secretase cleavage of Notch-1. EMBO J. 21 (2002) 5408-5416
-
(2002)
EMBO J.
, vol.21
, pp. 5408-5416
-
-
Okochi, M.1
Steiner, H.2
Fukumori, A.3
Tanii, H.4
Tomita, T.5
Tanaka, T.6
Iwatsubo, T.7
Kudo, T.8
Takeda, M.9
Haass, C.10
|