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Volumn 20, Issue 2, 2005, Pages 372-383

Progressive neurodegeneration in C. elegans model of tauopathy

Author keywords

C. elegans; FTDP 17; Neurodegeneration; tau; Tauopathy; Touch neuron

Indexed keywords

GLYCOGEN SYNTHASE KINASE 3; HEAT SHOCK PROTEIN 70; TAU PROTEIN;

EID: 26944463072     PISSN: 09699961     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.nbd.2005.03.017     Document Type: Article
Times cited : (86)

References (64)
  • 1
    • 0037444446 scopus 로고    scopus 로고
    • Heat shock protein 70 chaperone overexpression ameliorates phenotypes of the spinal and bulbar muscular atrophy transgenic mouse model by reducing nuclear-localized mutant androgen receptor protein
    • H. Adachi, M. Katsuno, M. Minamiyama, C. Sang, G. Pagoulatos, C. Angelidis, M. Kusakabe, A. Yoshiki, Y. Kobayashi, M. Doyu, and G. Sobue Heat shock protein 70 chaperone overexpression ameliorates phenotypes of the spinal and bulbar muscular atrophy transgenic mouse model by reducing nuclear-localized mutant androgen receptor protein J. Neurosci. 23 2003 2203 2211
    • (2003) J. Neurosci. , vol.23 , pp. 2203-2211
    • Adachi, H.1    Katsuno, M.2    Minamiyama, M.3    Sang, C.4    Pagoulatos, G.5    Angelidis, C.6    Kusakabe, M.7    Yoshiki, A.8    Kobayashi, Y.9    Doyu, M.10    Sobue, G.11
  • 3
    • 0036937699 scopus 로고    scopus 로고
    • Specific tau phosphorylation sites correlate with severity of neuronal cytopathology in Alzheimer's disease
    • J.C. Augustinack, A. Schneider, E.M. Mandelkow, and B.T. Hyman Specific tau phosphorylation sites correlate with severity of neuronal cytopathology in Alzheimer's disease Acta Neuropathol. (Berl.) 103 2002 26 35
    • (2002) Acta Neuropathol. (Berl.) , vol.103 , pp. 26-35
    • Augustinack, J.C.1    Schneider, A.2    Mandelkow, E.M.3    Hyman, B.T.4
  • 4
    • 0031007546 scopus 로고    scopus 로고
    • Regulated phosphorylation and dephosphorylation of tau protein: Effects on microtubule interaction, intracellular trafficking and neurodegeneration
    • M.L. Billingsley, and R.L. Kincaid Regulated phosphorylation and dephosphorylation of tau protein: effects on microtubule interaction, intracellular trafficking and neurodegeneration Biochem. J. 323 Pt. 3 1997 577 591
    • (1997) Biochem. J. , vol.323 , Issue.PART 3 , pp. 577-591
    • Billingsley, M.L.1    Kincaid, R.L.2
  • 5
    • 0016063911 scopus 로고
    • The genetics of Caenorhabditis elegans
    • S. Brenner The genetics of Caenorhabditis elegans Genetics 77 1974 71 94
    • (1974) Genetics , vol.77 , pp. 71-94
    • Brenner, S.1
  • 7
    • 0024536382 scopus 로고
    • Genetic control of differentiation of the Caenorhabditis elegans touch receptor neurons
    • M. Chalfie, and M. Au Genetic control of differentiation of the Caenorhabditis elegans touch receptor neurons Science 243 1989 1027 1033
    • (1989) Science , vol.243 , pp. 1027-1033
    • Chalfie, M.1    Au, M.2
  • 8
    • 0019546209 scopus 로고
    • Developmental genetics of the mechanosensory neurons of Caenorhabditis elegans
    • M. Chalfie, and J. Sulston Developmental genetics of the mechanosensory neurons of Caenorhabditis elegans Dev. Biol. 82 1981 358 370
    • (1981) Dev. Biol. , vol.82 , pp. 358-370
    • Chalfie, M.1    Sulston, J.2
  • 9
    • 0020061796 scopus 로고
    • Structural and functional diversity in the neuronal microtubules of Caenorhabditis elegans
    • M. Chalfie, and J.N. Thomson Structural and functional diversity in the neuronal microtubules of Caenorhabditis elegans J. Cell Biol. 93 1982 15 23
    • (1982) J. Cell Biol. , vol.93 , pp. 15-23
    • Chalfie, M.1    Thomson, J.N.2
  • 10
    • 0346218254 scopus 로고    scopus 로고
    • Atypical role of proximal caspase-8 in truncated Tau-induced neurite regression and neuronal cell death
    • C.W. Chung, Y.M. Hong, S. Song, H.N. Woo, Y.H. Choi, T. Rohn, and Y.K. Jung Atypical role of proximal caspase-8 in truncated Tau-induced neurite regression and neuronal cell death Neurobiol. Dis. 14 2003 557 566
    • (2003) Neurobiol. Dis. , vol.14 , pp. 557-566
    • Chung, C.W.1    Hong, Y.M.2    Song, S.3    Woo, H.N.4    Choi, Y.H.5    Rohn, T.6    Jung, Y.K.7
  • 12
    • 0027534862 scopus 로고
    • Lack of the carboxyl terminal sequence of tau in ghost tangles of Alzheimer's disease
    • R. Endoh, M. Ogawara, T. Iwatsubo, I. Nakano, and H. Mori Lack of the carboxyl terminal sequence of tau in ghost tangles of Alzheimer's disease Brain Res. 601 1993 164 172
    • (1993) Brain Res. , vol.601 , pp. 164-172
    • Endoh, R.1    Ogawara, M.2    Iwatsubo, T.3    Nakano, I.4    Mori, H.5
  • 13
    • 0037111833 scopus 로고    scopus 로고
    • Tau-mediated cytotoxicity in a pseudohyperphosphorylation model of Alzheimer's disease
    • T. Fath, J. Eidenmuller, and R. Brandt Tau-mediated cytotoxicity in a pseudohyperphosphorylation model of Alzheimer's disease J. Neurosci. 22 2002 9733 9741
    • (2002) J. Neurosci. , vol.22 , pp. 9733-9741
    • Fath, T.1    Eidenmuller, J.2    Brandt, R.3
  • 15
    • 0030963035 scopus 로고    scopus 로고
    • Phosphorylation of microtubule-associated protein tau by stress-activated protein kinases
    • M. Goedert, M. Hasegawa, R. Jakes, S. Lawler, A. Cuenda, and P. Cohen Phosphorylation of microtubule-associated protein tau by stress-activated protein kinases FEBS Lett. 409 1997 57 62
    • (1997) FEBS Lett. , vol.409 , pp. 57-62
    • Goedert, M.1    Hasegawa, M.2    Jakes, R.3    Lawler, S.4    Cuenda, A.5    Cohen, P.6
  • 17
    • 0035808361 scopus 로고    scopus 로고
    • Tau filament formation in transgenic mice expressing P301L tau
    • J. Gotz, F. Chen, R. Barmettler, and R.M. Nitsch Tau filament formation in transgenic mice expressing P301L tau J. Biol. Chem. 276 2001 529 534
    • (2001) J. Biol. Chem. , vol.276 , pp. 529-534
    • Gotz, J.1    Chen, F.2    Barmettler, R.3    Nitsch, R.M.4
  • 18
    • 0026766321 scopus 로고
    • The mec-7 beta-tubulin gene of Caenorhabditis elegans is expressed primarily in the touch receptor neurons
    • M. Hamelin, I.M. Scott, J.C. Way, and J.G. Culotti The mec-7 beta-tubulin gene of Caenorhabditis elegans is expressed primarily in the touch receptor neurons EMBO J. 11 1992 2885 2889
    • (1992) EMBO J. , vol.11 , pp. 2885-2889
    • Hamelin, M.1    Scott, I.M.2    Way, J.C.3    Culotti, J.G.4
  • 19
    • 0030240325 scopus 로고    scopus 로고
    • Reduction of acetylated alpha-tubulin immunoreactivity in neurofibrillary tangle-bearing neurons in Alzheimer's disease
    • B. Hempen, and J.P. Brion Reduction of acetylated alpha-tubulin immunoreactivity in neurofibrillary tangle-bearing neurons in Alzheimer's disease J. Neuropathol. Exp. Neurol. 55 1996 964 972
    • (1996) J. Neuropathol. Exp. Neurol. , vol.55 , pp. 964-972
    • Hempen, B.1    Brion, J.P.2
  • 21
    • 0033230886 scopus 로고    scopus 로고
    • Age-dependent emergence and progression of a tauopathy in transgenic mice overexpressing the shortest human tau isoform
    • T. Ishihara, M. Hong, B. Zhang, Y. Nakagawa, M.K. Lee, J.Q. Trojanowski, and V.M. Lee Age-dependent emergence and progression of a tauopathy in transgenic mice overexpressing the shortest human tau isoform Neuron 24 1999 751 762
    • (1999) Neuron , vol.24 , pp. 751-762
    • Ishihara, T.1    Hong, M.2    Zhang, B.3    Nakagawa, Y.4    Lee, M.K.5    Trojanowski, J.Q.6    Lee, V.M.7
  • 22
    • 0035134081 scopus 로고    scopus 로고
    • Age-dependent induction of congophilic neurofibrillary tau inclusions in tau transgenic mice
    • T. Ishihara, B. Zhang, M. Higuchi, Y. Yoshiyama, J.Q. Trojanowski, and V.M. Lee Age-dependent induction of congophilic neurofibrillary tau inclusions in tau transgenic mice Am. J. Pathol. 158 2001 555 562
    • (2001) Am. J. Pathol. , vol.158 , pp. 555-562
    • Ishihara, T.1    Zhang, B.2    Higuchi, M.3    Yoshiyama, Y.4    Trojanowski, J.Q.5    Lee, V.M.6
  • 23
    • 0026569062 scopus 로고
    • Lack of ubiquitin immunoreactivities at both ends of neuropil threads. Possible bidirectional growth of neuropil threads
    • T. Iwatsubo, M. Hasegawa, Y. Esaki, and Y. Ihara Lack of ubiquitin immunoreactivities at both ends of neuropil threads. Possible bidirectional growth of neuropil threads Am. J. Pathol. 140 1992 277 282
    • (1992) Am. J. Pathol. , vol.140 , pp. 277-282
    • Iwatsubo, T.1    Hasegawa, M.2    Esaki, Y.3    Ihara, Y.4
  • 24
    • 18644379256 scopus 로고    scopus 로고
    • Testosterone reduction prevents phenotypic expression in a transgenic mouse model of spinal and bulbar muscular atrophy
    • M. Katsuno, H. Adachi, A. Kume, M. Li, Y. Nakagomi, H. Niwa, C. Sang, Y. Kobayashi, M. Doyu, and G. Sobue Testosterone reduction prevents phenotypic expression in a transgenic mouse model of spinal and bulbar muscular atrophy Neuron 35 2002 843 854
    • (2002) Neuron , vol.35 , pp. 843-854
    • Katsuno, M.1    Adachi, H.2    Kume, A.3    Li, M.4    Nakagomi, Y.5    Niwa, H.6    Sang, C.7    Kobayashi, Y.8    Doyu, M.9    Sobue, G.10
  • 25
    • 0034596988 scopus 로고    scopus 로고
    • A Caenorhabditis elegans MAP kinase kinase, MEK-1, is involved in stress responses
    • M. Koga, R. Zwaal, K.L. Guan, L. Avery, and Y. Ohshima A Caenorhabditis elegans MAP kinase kinase, MEK-1, is involved in stress responses EMBO J. 19 2000 5148 5156
    • (2000) EMBO J. , vol.19 , pp. 5148-5156
    • Koga, M.1    Zwaal, R.2    Guan, K.L.3    Avery, L.4    Ohshima, Y.5
  • 27
    • 1542289803 scopus 로고    scopus 로고
    • Mutant (R406W) human tau is hyperphosphorylated and does not efficiently bind microtubules in a neuronal cortical cell model
    • P.K. Krishnamurthy, and G.V. Johnson Mutant (R406W) human tau is hyperphosphorylated and does not efficiently bind microtubules in a neuronal cortical cell model J. Biol. Chem. 279 2004 7893 7900
    • (2004) J. Biol. Chem. , vol.279 , pp. 7893-7900
    • Krishnamurthy, P.K.1    Johnson, G.V.2
  • 28
    • 0025904444 scopus 로고
    • A68: A major subunit of paired helical filaments and derivatized forms of normal Tau
    • V.M. Lee, B.J. Balin, L. Otvos Jr., and J.Q. Trojanowski A68: a major subunit of paired helical filaments and derivatized forms of normal Tau Science 251 1991 675 678
    • (1991) Science , vol.251 , pp. 675-678
    • Lee, V.M.1    Balin, B.J.2    Otvos Jr., L.3    Trojanowski, J.Q.4
  • 31
    • 0035680685 scopus 로고    scopus 로고
    • FTDP-17 mutations in tau transgenic mice provoke lysosomal abnormalities and Tau filaments in forebrain
    • F. Lim, F. Hernandez, J.J. Lucas, P. Gomez-Ramos, M.A. Moran, and J. Avila FTDP-17 mutations in tau transgenic mice provoke lysosomal abnormalities and Tau filaments in forebrain Mol. Cell. Neurosci. 18 2001 702 714
    • (2001) Mol. Cell. Neurosci. , vol.18 , pp. 702-714
    • Lim, F.1    Hernandez, F.2    Lucas, J.J.3    Gomez-Ramos, P.4    Moran, M.A.5    Avila, J.6
  • 32
    • 0028818537 scopus 로고
    • Identification and cloning of unc-119, a gene expressed in the Caenorhabditis elegans nervous system
    • M. Maduro, and D. Pilgrim Identification and cloning of unc-119, a gene expressed in the Caenorhabditis elegans nervous system Genetics 141 1995 977 988
    • (1995) Genetics , vol.141 , pp. 977-988
    • Maduro, M.1    Pilgrim, D.2
  • 33
    • 0345276565 scopus 로고    scopus 로고
    • Clogging of axons by tau, inhibition of axonal traffic and starvation of synapses
    • E.M. Mandelkow, K. Stamer, R. Vogel, E. Thies, and E. Mandelkow Clogging of axons by tau, inhibition of axonal traffic and starvation of synapses Neurobiol. Aging 24 2003 1079 1085
    • (2003) Neurobiol. Aging , vol.24 , pp. 1079-1085
    • Mandelkow, E.M.1    Stamer, K.2    Vogel, R.3    Thies, E.4    Mandelkow, E.5
  • 35
    • 0033055359 scopus 로고    scopus 로고
    • Stable expression in Chinese hamster ovary cells of mutated tau genes causing frontotemporal dementia and parkinsonism linked to chromosome 17 (FTDP-17)
    • N. Matsumura, T. Yamazaki, and Y. Ihara Stable expression in Chinese hamster ovary cells of mutated tau genes causing frontotemporal dementia and parkinsonism linked to chromosome 17 (FTDP-17) Am. J. Pathol. 154 1999 1649 1656
    • (1999) Am. J. Pathol. , vol.154 , pp. 1649-1656
    • Matsumura, N.1    Yamazaki, T.2    Ihara, Y.3
  • 36
    • 0027945346 scopus 로고
    • Biopsy-derived adult human brain tau is phosphorylated at many of the same sites as Alzheimer's disease paired helical filament tau
    • E.S. Matsuo, R.W. Shin, M.L. Billingsley, A. Van deVoorde, M. O'Connor, J.Q. Trojanowski, and V.M. Lee Biopsy-derived adult human brain tau is phosphorylated at many of the same sites as Alzheimer's disease paired helical filament tau Neuron 13 1994 989 1002
    • (1994) Neuron , vol.13 , pp. 989-1002
    • Matsuo, E.S.1    Shin, R.W.2    Billingsley, M.L.3    Van Devoorde, A.4    O'Connor, M.5    Trojanowski, J.Q.6    Lee, V.M.7
  • 38
    • 0025942107 scopus 로고
    • Efficient gene transfer in C.elegans: Extrachromosomal maintenance and integration of transforming sequences
    • C.C. Mello, J.M. Kramer, D. Stinchcomb, and V. Ambros Efficient gene transfer in C.elegans: extrachromosomal maintenance and integration of transforming sequences EMBO J. 10 1991 3959 3970
    • (1991) EMBO J. , vol.10 , pp. 3959-3970
    • Mello, C.C.1    Kramer, J.M.2    Stinchcomb, D.3    Ambros, V.4
  • 39
    • 0028848587 scopus 로고
    • Genetic regulation of mec-3 gene expression implicated in the specification of the mechanosensory neuron cell types in Caenorhabditis elegans
    • S. Mitani Genetic regulation of mec-3 gene expression implicated in the specification of the mechanosensory neuron cell types in Caenorhabditis elegans Dev. Growth Differ. 37 1995 551 557
    • (1995) Dev. Growth Differ. , vol.37 , pp. 551-557
    • Mitani, S.1
  • 43
  • 44
    • 0037014426 scopus 로고    scopus 로고
    • Protein misfolding, amyloid formation, and neurodegeneration: A critical role for molecular chaperones?
    • P.J. Muchowski Protein misfolding, amyloid formation, and neurodegeneration: a critical role for molecular chaperones? Neuron 35 2002 9 12
    • (2002) Neuron , vol.35 , pp. 9-12
    • Muchowski, P.J.1
  • 46
    • 1542358895 scopus 로고    scopus 로고
    • PAR-1 kinase plays an initiator role in a temporally ordered phosphorylation process that confers tau toxicity in Drosophila
    • I. Nishimura, Y. Yang, and B. Lu PAR-1 kinase plays an initiator role in a temporally ordered phosphorylation process that confers tau toxicity in Drosophila Cell 116 2004 671 682
    • (2004) Cell , vol.116 , pp. 671-682
    • Nishimura, I.1    Yang, Y.2    Lu, B.3
  • 47
    • 0035818590 scopus 로고    scopus 로고
    • Expanded polyglutamines in Caenorhabditis elegans cause axonal abnormalities and severe dysfunction of PLM mechanosensory neurons without cell death
    • J.A. Parker, J.B. Connolly, C. Wellington, M. Hayden, J. Dausset, and C. Neri Expanded polyglutamines in Caenorhabditis elegans cause axonal abnormalities and severe dysfunction of PLM mechanosensory neurons without cell death Proc. Natl. Acad. Sci. U. S. A. 98 2001 13318 13323
    • (2001) Proc. Natl. Acad. Sci. U. S. A. , vol.98 , pp. 13318-13323
    • Parker, J.A.1    Connolly, J.B.2    Wellington, C.3    Hayden, M.4    Dausset, J.5    Neri, C.6
  • 53
    • 0024688962 scopus 로고
    • Mec-7 is a beta-tubulin gene required for the production of 15-protofilament microtubules in Caenorhabditis elegans
    • C. Savage, M. Hamelin, J.G. Culotti, A. Coulson, D.G. Albertson, and M. Chalfie mec-7 is a beta-tubulin gene required for the production of 15-protofilament microtubules in Caenorhabditis elegans Genes Dev. 3 1989 870 881
    • (1989) Genes Dev. , vol.3 , pp. 870-881
    • Savage, C.1    Hamelin, M.2    Culotti, J.G.3    Coulson, A.4    Albertson, D.G.5    Chalfie, M.6
  • 54
    • 0024407429 scopus 로고
    • Anti-tubulin monoclonal antibodies that bind to specific neurons in Caenorhabditis elegans
    • S.S. Siddiqui, E. Aamodt, F. Rastinejad, and J. Culotti Anti-tubulin monoclonal antibodies that bind to specific neurons in Caenorhabditis elegans J. Neurosci. 9 1989 2963 2972
    • (1989) J. Neurosci. , vol.9 , pp. 2963-2972
    • Siddiqui, S.S.1    Aamodt, E.2    Rastinejad, F.3    Culotti, J.4
  • 62
    • 0035903537 scopus 로고    scopus 로고
    • Jkk-1 and mek-1 regulate body movement coordination and response to heavy metals through jnk-1 in Caenorhabditis elegans
    • A. Villanueva, J. Lozano, A. Morales, X. Lin, X. Deng, M.O. Hengartner, and R.N. Kolesnick jkk-1 and mek-1 regulate body movement coordination and response to heavy metals through jnk-1 in Caenorhabditis elegans EMBO J. 20 2001 5114 5128
    • (2001) EMBO J. , vol.20 , pp. 5114-5128
    • Villanueva, A.1    Lozano, J.2    Morales, A.3    Lin, X.4    Deng, X.5    Hengartner, M.O.6    Kolesnick, R.N.7
  • 63
    • 0024043341 scopus 로고
    • Mec-3, a homeobox-containing gene that specifies differentiation of the touch receptor neurons in C. elegans
    • J.C. Way, and M. Chalfie mec-3, a homeobox-containing gene that specifies differentiation of the touch receptor neurons in C. elegans Cell 54 1988 5 16
    • (1988) Cell , vol.54 , pp. 5-16
    • Way, J.C.1    Chalfie, M.2


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