메뉴 건너뛰기




Volumn 3, Issue 1, 2006, Pages 55-62

Discovery of neurogenic, Alzheimer's disease therapeutics

Author keywords

Alzheimer's disease; Neurodegeneration; Neurogenesis; Signaling; Therapeutics

Indexed keywords

1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; 2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 2 MORPHOLINO 8 PHENYLCHROMONE; 4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; ALCOHOL; AMYLOID BETA PROTEIN[1-42]; AMYLOID BETA PROTEIN[25-35]; ANTIDEPRESSANT AGENT; BRAIN DERIVED NEUROTROPHIC FACTOR; CEP 11004; CYCLIC AMP; ERYTHROPOIETIN; FLUOXETINE; HORMONE RECEPTOR BLOCKING AGENT; HORMONE RECEPTOR STIMULATING AGENT; LITHIUM CHLORIDE; LY 451646; MITOGEN ACTIVATED PROTEIN KINASE INHIBITOR; MOOD STABILIZER; NEUROPEPTIDE Y; NEUROSTEROID; NEUROTROPHIC FACTOR; NOTCH RECEPTOR; PREGNENOLONE; ROLIPRAM; SEROTONIN UPTAKE INHIBITOR; SOMATOMEDIN C; SONIC HEDGEHOG AGONIST; SONIC HEDGEHOG ANTAGONIST; SONIC HEDGEHOG PROTEIN; TIANEPTINE; TRICYCLIC ANTIDEPRESSANT AGENT; UNCLASSIFIED DRUG; UNINDEXED DRUG; VALPROIC ACID; WNT PROTEIN;

EID: 33645886343     PISSN: 15672050     EISSN: None     Source Type: Journal    
DOI: 10.2174/156720506775697179     Document Type: Conference Paper
Times cited : (13)

References (83)
  • 1
    • 0347763627 scopus 로고    scopus 로고
    • Neural stem cell therapy in the aging brain: Pitfalls and possibilities
    • Limke TL and Rao MS. Neural stem cell therapy in the aging brain: Pitfalls and possibilities. J. Hematotherapy and Stem Cell Research 12:615-623 (2003).
    • (2003) J. Hematotherapy and Stem Cell Research , vol.12 , pp. 615-623
    • Limke, T.L.1    Rao, M.S.2
  • 2
    • 0001159822 scopus 로고
    • Are new neurons formed in the brains of adult mammals?
    • Altman J. Are new neurons formed in the brains of adult mammals? J Comp Neurol 135:1127-28 (1962).
    • (1962) J Comp Neurol , vol.135 , pp. 1127-1128
    • Altman, J.1
  • 3
    • 0013784893 scopus 로고
    • Autoradiographic and histological evidence of postnatal hippocampal neurogenesis in rats
    • Altman J, and Das GD. Autoradiographic and histological evidence of postnatal hippocampal neurogenesis in rats. J Comp Neurol 124:319-35 (1965).
    • (1965) J Comp Neurol , vol.124 , pp. 319-335
    • Altman, J.1    Das, G.D.2
  • 4
    • 0034702121 scopus 로고    scopus 로고
    • Induction of neurogeneisis in the neocortex of adult mice
    • Magavi SS, Leavitt BR, and Macklis JD. Induction of neurogeneisis in the neocortex of adult mice. Nature 405:951-955 (2000).
    • (2000) Nature , vol.405 , pp. 951-955
    • Magavi, S.S.1    Leavitt, B.R.2    Macklis, J.D.3
  • 6
    • 0035836656 scopus 로고    scopus 로고
    • Neurogenesis in dentate subgranular zone and rostral subventricular zone after focal cerebral ischemia in the rat
    • USA
    • Jin K, Minami M, Lan JQ, Mao XO, Batteur S, Simon RP, and Greenberg DA. Neurogenesis in dentate subgranular zone and rostral subventricular zone after focal cerebral ischemia in the rat. Proc Natl Acad Sci USA 58 (8): 4710-4715 (2001).
    • (2001) Proc Natl Acad Sci , vol.58 , Issue.8 , pp. 4710-4715
    • Jin, K.1    Minami, M.2    Lan, J.Q.3    Mao, X.O.4    Batteur, S.5    Simon, R.P.6    Greenberg, D.A.7
  • 7
    • 4344670964 scopus 로고    scopus 로고
    • Neurogenesis response to hypoxia-induced cell death: Map kinase signal transduction mechanisms
    • Zhou, L, Del Villar K, Dong Z, Miller CA. Neurogenesis response to hypoxia-induced cell death: map kinase signal transduction mechanisms. Brain Res 17 (1021):8-19 (2004).
    • (2004) Brain Res , vol.17 , Issue.1021 , pp. 8-19
    • Zhou, L.1    Del Villar, K.2    Dong, Z.3    Miller, C.A.4
  • 8
    • 0037162691 scopus 로고    scopus 로고
    • Regeneration of hippocampal pyramidal neurons after ischemic brain injury by recruitment of endogenous neural progenitors
    • Nakatomi H, Kuriu T, Okabe S, Yamamoto S, Hatano O, Kawahara N, Tamura A, Kirino T, Nakafuku M. Regeneration of hippocampal pyramidal neurons after ischemic brain injury by recruitment of endogenous neural progenitors. Cell 110:429-441 (2002).
    • (2002) Cell , vol.110 , pp. 429-441
    • Nakatomi, H.1    Kuriu, T.2    Okabe, S.3    Yamamoto, S.4    Hatano, O.5    Kawahara, N.6    Tamura, A.7    Kirino, T.8    Nakafuku, M.9
  • 9
    • 0034846836 scopus 로고    scopus 로고
    • Cortical neurogenesis in adult rats after transient middle cerebral artery occlusion
    • Jiang W, Weigang G, Brannstrom T, Rosqvist R, and Wester P. Cortical neurogenesis in adult rats after transient middle cerebral artery occlusion. Stroke 32:1201-1207 (2001).
    • (2001) Stroke , vol.32 , pp. 1201-1207
    • Jiang, W.1    Weigang, G.2    Brannstrom, T.3    Rosqvist, R.4    Wester, P.5
  • 10
    • 0033564083 scopus 로고    scopus 로고
    • Enriched environment increases neurogenesis in the adult rat dentate gyrus and improves spatial memory
    • Nilsson M, Perfilieva E, Johansson U, Orwar O, and Eriksson PS. Enriched environment increases neurogenesis in the adult rat dentate gyrus and improves spatial memory. J Neurobiol 39(4):569-78 (1999).
    • (1999) J Neurobiol , vol.39 , Issue.4 , pp. 569-578
    • Nilsson, M.1    Perfilieva, E.2    Johansson, U.3    Orwar, O.4    Eriksson, P.S.5
  • 11
    • 0036325981 scopus 로고    scopus 로고
    • Neuroplasticity in Old Age: Sustained fivefold induction of hippocampal neurogenesis by long-term environmental enrichment
    • Kempermann G, Gast D, and Gage FH. Neuroplasticity in Old Age: Sustained fivefold induction of hippocampal neurogenesis by long-term environmental enrichment. Annals Neurology 52:135-43 (2002).
    • (2002) Annals Neurology , vol.52 , pp. 135-143
    • Kempermann, G.1    Gast, D.2    Gage, F.H.3
  • 12
    • 0033539607 scopus 로고    scopus 로고
    • Running enhances neurogenesis, learning and long-term potentiation in mice
    • USA
    • van Praag H, Christie BR, Sejnowski TJ, and Gage FH. Running enhances neurogenesis, learning and long-term potentiation in mice. Proc Natl Acad Sci USA 96(23):13427-431 (1999).
    • (1999) Proc Natl Acad Sci , vol.96 , Issue.23 , pp. 13427-13431
    • Praag, H.1    Christie, B.R.2    Sejnowski, T.J.3    Gage, F.H.4
  • 13
    • 0032972245 scopus 로고    scopus 로고
    • Experience-dependent regulation of adult hippocampal neurogenesis: Effects of long-term stimulation and stimulus withdrawal
    • Kempermann G, Gage FH. Experience-dependent regulation of adult hippocampal neurogenesis: effects of long-term stimulation and stimulus withdrawal. Hippocampus 9(3):321-332 (1999).
    • (1999) Hippocampus , vol.9 , Issue.3 , pp. 321-332
    • Kempermann, G.1    Gage, F.H.2
  • 14
    • 0035866067 scopus 로고    scopus 로고
    • Enhanced neurogenesis in the rodent hippocampus following traumatic brain injury
    • Dash PK, Mach SA, and Moore AN. Enhanced neurogenesis in the rodent hippocampus following traumatic brain injury. J Neurosci Res 63(4):313-319 (2001).
    • (2001) J Neurosci Res , vol.63 , Issue.4 , pp. 313-319
    • Dash, P.K.1    Mach, S.A.2    Moore, A.N.3
  • 15
    • 0033363319 scopus 로고    scopus 로고
    • Learning enhances adult neurogenesis in the hippocampal formation
    • Gould E, Beylin A, Tanapat P, Reeves A, and Shors TJ. Learning enhances adult neurogenesis in the hippocampal formation. Nature Neurosci 2(3):260-65 1999).
    • (1999) Nature Neurosci , vol.2 , Issue.3 , pp. 260-265
    • Gould, E.1    Beylin, A.2    Tanapat, P.3    Reeves, A.4    Shors, T.J.5
  • 18
    • 0035940496 scopus 로고    scopus 로고
    • Stress-induced changes in cerebral metabolites, hippocampal volume, and cell proliferation are prevented by antidepressant treatment with tianeptine
    • USA
    • Czeh, B., Michaelis, T., Watanabe, T., Frahm, J., de Biurrun, G., van Kampen, M., Bartolomucci, A., and Fuchs E. Stress-induced changes in cerebral metabolites, hippocampal volume, and cell proliferation are prevented by antidepressant treatment with tianeptine. Proc Natl Acad Sci USA 98 (22):12796-12801 (2001).
    • (2001) Proc Natl Acad Sci , vol.98 , Issue.22 , pp. 12796-12801
    • Czeh, B.1    Michaelis, T.2    Watanabe, T.3    Frahm, J.4    De Biurrun, G.5    Van Kampen, M.6    Bartolomucci, A.7    Fuchs, E.8
  • 19
    • 0141669079 scopus 로고    scopus 로고
    • Cell proliferation in adult hippocampus is decreased by inescapable stress: Reversal by fluoxetine treatment
    • Malberg JE and Duman RS. Cell proliferation in adult hippocampus is decreased by inescapable stress: reversal by fluoxetine treatment. Neuropsychopharm 28(9):1562-1571 (2003).
    • (2003) Neuropsychopharm , vol.28 , Issue.9 , pp. 1562-1571
    • Malberg, J.E.1    Duman, R.S.2
  • 20
    • 3343015515 scopus 로고    scopus 로고
    • Modulation of hippocampal cell proliferation, memory, and amyloid plaque deposition in APPsw (Tg2576) mutant mice by isolation stress
    • Dong H, Goico B, Martin M, Csernansky CA, Bertchume A, and Csernansky JG. Modulation of hippocampal cell proliferation, memory, and amyloid plaque deposition in APPsw (Tg2576) mutant mice by isolation stress. Neurosci 127:601-609 (2004).
    • (2004) Neurosci , vol.127 , pp. 601-609
    • Dong, H.1    Goico, B.2    Martin, M.3    Csernansky, C.A.4    Bertchume, A.5    Csernansky, J.G.6
  • 21
    • 1842426600 scopus 로고    scopus 로고
    • Differential effects of corticosterone and dexamethasone on hippocampal neurogenesis in vitro
    • Yu IT, Lee SH, Lee YS, and Son H. Differential effects of corticosterone and dexamethasone on hippocampal neurogenesis in vitro. Biochem Biophys Res Commun 317(2):484-490 (2004).
    • (2004) Biochem Biophys Res Commun , vol.317 , Issue.2 , pp. 484-490
    • Yu, I.T.1    Lee, S.H.2    Lee, Y.S.3    Son, H.4
  • 24
    • 0344255828 scopus 로고    scopus 로고
    • Learning and adult neurogenesis: Survival with or without proliferation?
    • Prickaerts J, Koopmans G, Blokland A, and Scheepens A. Learning and adult neurogenesis: Survival with or without proliferation? Science 81:1-11 (2004).
    • (2004) Science , vol.81 , pp. 1-11
    • Prickaerts, J.1    Koopmans, G.2    Blokland, A.3    Scheepens, A.4
  • 25
  • 26
    • 0034854429 scopus 로고    scopus 로고
    • Pregnenolone sulfate and aging of cognitive functions: Behavioral, neurochemical, and morphological investigations
    • Mayo W, LeMoal M, Abrous DN. Pregnenolone sulfate and aging of cognitive functions: behavioral, neurochemical, and morphological investigations. Horm Behav 40(2):215-217 (2001).
    • (2001) Horm Behav , vol.40 , Issue.2 , pp. 215-217
    • Mayo, W.1    LeMoal, M.2    Abrous, D.N.3
  • 27
    • 0035965708 scopus 로고    scopus 로고
    • Intracerebroventricular infusion of insulin-like growth factor-1 ameliorates the age-related decline in hippocampal neurogenesis
    • Lichtenwalner, R.J., Forbes, M.E., Bennett, S.A., Lynch, C.D., Sonntag, W.E., and Riddle, D.R. Intracerebroventricular infusion of insulin-like growth factor-1 ameliorates the age-related decline in hippocampal neurogenesis. Neuroscience 107 (4):603-613 (2001).
    • (2001) Neuroscience , vol.107 , Issue.4 , pp. 603-613
    • Lichtenwalner, R.J.1    Forbes, M.E.2    Bennett, S.A.3    Lynch, C.D.4    Sonntag, W.E.5    Riddle, D.R.6
  • 28
    • 0034671366 scopus 로고    scopus 로고
    • Chronic antidepressant treatment increases neurogenesis in adult rat hippocampus
    • Malberg JE, Eisch AJ, Nestler EJ and Duman RS. Chronic antidepressant treatment increases neurogenesis in adult rat hippocampus. J Neurosci 20(24):9104-9110 (2000).
    • (2000) J Neurosci , vol.20 , Issue.24 , pp. 9104-9110
    • Malberg, J.E.1    Eisch, A.J.2    Nestler, E.J.3    Duman, R.S.4
  • 30
    • 0037451782 scopus 로고    scopus 로고
    • Lithium stimulates progenitor proliferation in cultured brain neurons
    • Hashimoto R, Senatorov V, Kanai H, Leeds P, and Chuang D-M. Lithium stimulates progenitor proliferation in cultured brain neurons. Neurosci 117(1):55-61 (2003).
    • (2003) Neurosci , vol.117 , Issue.1 , pp. 55-61
    • Hashimoto, R.1    Senatorov, V.2    Kanai, H.3    Leeds, P.4    Chuang, D.-M.5
  • 32
    • 11844288312 scopus 로고    scopus 로고
    • Increasing hippocampal neurogenesis: A novel mechanism for antidepressant drugs
    • Malberg JE, and Schechter LE. Increasing hippocampal neurogenesis: a novel mechanism for antidepressant drugs. Curr Pharm Des 11(2):145-155 (2005).
    • (2005) Curr Pharm des , vol.11 , Issue.2 , pp. 145-155
    • Malberg, J.E.1    Schechter, L.E.2
  • 34
    • 0021929644 scopus 로고
    • Pharmacological studies on sufoxazine (Y-8894). (I) Effects on experimental amnesia in mice
    • Anami K, Yamamoto Y, and Setoguchi M. Pharmacological studies on sufoxazine (Y-8894). (I) Effects on experimental amnesia in mice. Nippom Yakurigaku Zasshi 85(2):71-7 (1985).
    • (1985) Nippom Yakurigaku Zasshi , vol.85 , Issue.2 , pp. 71-77
    • Anami, K.1    Yamamoto, Y.2    Setoguchi, M.3
  • 35
    • 0026612102 scopus 로고
    • The future of 5-HT1A receptor agonists. (Aryl-piperazine derivatives)
    • Murasaki M and Miura S. The future of 5-HT1A receptor agonists. (Aryl-piperazine derivatives). Prog Neuropsychopharmacol Biol Psychiatry 16(6):883-45 (1992).
    • (1992) Prog Neuropsychopharmacol Biol Psychiatry , vol.16 , Issue.6 , pp. 883-945
    • Murasaki, M.1    Miura, S.2
  • 36
    • 0027869618 scopus 로고
    • Alprozolam modifies animal behavior on elevated plus-maze
    • Kulkarni SK and Sharma K. Alprozolam modifies animal behavior on elevated plus-maze. Indian J Exp Biol 31(11):908-911 (1993).
    • (1993) Indian J Exp Biol , vol.31 , Issue.11 , pp. 908-911
    • Kulkarni, S.K.1    Sharma, K.2
  • 37
    • 0033956163 scopus 로고    scopus 로고
    • Regulation of neuronal differentiation in human CNS stem cell progeny by leukemia inhibitory factor
    • Galli R, Pagano SF, Gritti A, Vescovi AL. Regulation of neuronal differentiation in human CNS stem cell progeny by leukemia inhibitory factor. Dev Neurosci 22(1-2):86-95 (2000).
    • (2000) Dev Neurosci , vol.22 , Issue.1-2 , pp. 86-95
    • Galli, R.1    Pagano, S.F.2    Gritti, A.3    Vescovi, A.L.4
  • 39
    • 0033135389 scopus 로고    scopus 로고
    • Leukemia inhibitory factor augments neurotrophin expression and corticospinal axon growth after adult CNS injury
    • Blesch A, Uy HS, Grill RJ, Cheng JG, Patterson PH, and Tuszynski MH. Leukemia inhibitory factor augments neurotrophin expression and corticospinal axon growth after adult CNS injury. J Neurosci 19(9):3556-66 (1999).
    • (1999) J Neurosci , vol.19 , Issue.9 , pp. 3556-3566
    • Blesch, A.1    Uy, H.S.2    Grill, R.J.3    Cheng, J.G.4    Patterson, P.H.5    Tuszynski, M.H.6
  • 40
    • 0035894847 scopus 로고    scopus 로고
    • Erythropoietin regulates the in vitro and in vivo production of neuronal progenitors by mammalian forebrain neural stem cells
    • Shingo T, Sorokan ST, Shimazaki T, and Weiss S. Erythropoietin regulates the in vitro and in vivo production of neuronal progenitors by mammalian forebrain neural stem cells. J Neurosci 21(24):9733-43 (2001).
    • (2001) J Neurosci , vol.21 , Issue.24 , pp. 9733-9743
    • Shingo, T.1    Sorokan, S.T.2    Shimazaki, T.3    Weiss, S.4
  • 41
    • 33645876346 scopus 로고    scopus 로고
    • Personal Communication Kelleher-Andersson, J.
    • Personal Communication Kelleher-Andersson, J.
  • 42
    • 0029150839 scopus 로고
    • Functions of basic fibroblast growth factor and neurotrophins in the differentiation of hippocampal neurons
    • Vicario-Abejon C, Johe KK, Hazel TG, Collazo D, McKay RD. Functions of basic fibroblast growth factor and neurotrophins in the differentiation of hippocampal neurons. Neuron 15(1):105-114 (1995).
    • (1995) Neuron , vol.15 , Issue.1 , pp. 105-114
    • Vicario-Abejon, C.1    Johe, K.K.2    Hazel, T.G.3    Collazo, D.4    McKay, R.D.5
  • 43
    • 0036272279 scopus 로고    scopus 로고
    • Antidepressants and neuroplasticity
    • D'Sa C, and Duman RS. Antidepressants and neuroplasticity. Bipolar Disorders 4:183-194 (2002).
    • (2002) Bipolar Disorders , vol.4 , pp. 183-194
    • D'Sa, C.1    Duman, R.S.2
  • 45
    • 0141927282 scopus 로고    scopus 로고
    • Lithium treatment alters brain concentration of nerve growth factor, brainderived neurotrophic factor and glial cell line-derived neurotrophic factor in a rat model of depression
    • Angulucci F, Aloe L, Jimenez-Vasquez P, and Mathe AA. Lithium treatment alters brain concentration of nerve growth factor, brainderived neurotrophic factor and glial cell line-derived neurotrophic factor in a rat model of depression. Int J Neuropsychopharmacol 6(3):225-31 (2003).
    • (2003) Int J Neuropsychopharmacol , vol.6 , Issue.3 , pp. 225-231
    • Angulucci, F.1    Aloe, L.2    Jimenez-Vasquez, P.3    Mathe, A.A.4
  • 46
    • 0034795827 scopus 로고    scopus 로고
    • Chronic lithium treatment increases the expression of brain derived neurotrophic factor in the rat brain
    • Berl
    • Fukumoto T, Morinobu S, Okamoto Y, Kagaya A and Yamawaki S. Chronic lithium treatment increases the expression of brain derived neurotrophic factor in the rat brain. Psychopharmacol (Berl) 158(1):100-106 (2001).
    • (2001) Psychopharmacol , vol.158 , Issue.1 , pp. 100-106
    • Fukumoto, T.1    Morinobu, S.2    Okamoto, Y.3    Kagaya, A.4    Yamawaki, S.5
  • 47
  • 48
    • 0036839248 scopus 로고    scopus 로고
    • Neuron number in the parahippocampal region is preserved in aged rats with spatial learning deficits
    • Rapp PR, Deroche PS, Mao Y, and Burwell RD. Neuron number in the parahippocampal region is preserved in aged rats with spatial learning deficits. Cereb Cortes 12(11):1171-1179 (2002).
    • (2002) Cereb Cortes , vol.12 , Issue.11 , pp. 1171-1179
    • Rapp, P.R.1    Deroche, P.S.2    Mao, Y.3    Burwell, R.D.4
  • 49
    • 0034656167 scopus 로고    scopus 로고
    • Peripheral infusion of IGF-1 selectively induces neurogeneis in the adult rat hippocampus
    • [49 Aberg MA, Aberg ND, Hedbacker H, and Oscarsson J. Peripheral infusion of IGF-1 selectively induces neurogeneis in the adult rat hippocampus. J Neurosci 20(8):2896-903 (2000).
    • (2000) J Neurosci , vol.20 , Issue.8 , pp. 2896-2903
    • Aberg, M.A.1    Aberg, N.D.2    Hedbacker, H.3    Oscarsson, J.4
  • 50
    • 1842785189 scopus 로고    scopus 로고
    • Signaling by insulin-like growth factor 1 in brain
    • Bondy CA and Cheng CM. Signaling by insulin-like growth factor 1 in brain. Eur J Pharmacol 490(1-3):25-31 (2004).
    • (2004) Eur J Pharmacol , vol.490 , Issue.1-3 , pp. 25-31
    • Bondy, C.A.1    Cheng, C.M.2
  • 51
    • 3242788185 scopus 로고    scopus 로고
    • Mood stabilizer valproate promotes ERK pathwaydependent cortical neuronal growth and neurogenesis
    • Hao Y, Creson T, Zhang L, Li P, Yuan P, Gould TD, Manji HK, and Chen G. Mood stabilizer valproate promotes ERK pathwaydependent cortical neuronal growth and neurogenesis. J Neurosci 24(29):6590-6599 (2004).
    • (2004) J Neurosci , vol.24 , Issue.29 , pp. 6590-6599
    • Hao, Y.1    Creson, T.2    Zhang, L.3    Li, P.4    Yuan, P.5    Gould, T.D.6    Manji, H.K.7    Chen, G.8
  • 52
    • 0034044227 scopus 로고    scopus 로고
    • Neurotrophin signal transduction in the nervous system
    • Kaplan DR and Miller FD. Neurotrophin signal transduction in the nervous system. Curr Opin Neurobiol 10(3):381-391 (2000).
    • (2000) Curr Opin Neurobiol , vol.10 , Issue.3 , pp. 381-391
    • Kaplan, D.R.1    Miller, F.D.2
  • 53
    • 0038452619 scopus 로고    scopus 로고
    • Endogenously produced neurotrophins regulate survival and differentiation of cortical progenitors via distinct signaling pathways
    • Barnabe-Heider F, and Miller FD. Endogenously produced neurotrophins regulate survival and differentiation of cortical progenitors via distinct signaling pathways. J Neurosci 23(12):5149-5160 (2003).
    • (2003) J Neurosci , vol.23 , Issue.12 , pp. 5149-5160
    • Barnabe-Heider, F.1    Miller, F.D.2
  • 54
    • 5644293601 scopus 로고    scopus 로고
    • Dexamethasone inhibits proliferation of adult hippocampal neurogenesis in vivo and in vitro
    • Kim JB, Ju JY, Kim JH, Kim TY, Yang BH, Lee YS, and Son H. Dexamethasone inhibits proliferation of adult hippocampal neurogenesis in vivo and in vitro. Brain Res 1027(1-2):1-10 (2004).
    • (2004) Brain Res , vol.1027 , Issue.1-2 , pp. 1-10
    • Kim, J.B.1    Ju, J.Y.2    Kim, J.H.3    Kim, T.Y.4    Yang, B.H.5    Lee, Y.S.6    Son, H.7
  • 56
    • 2942530513 scopus 로고    scopus 로고
    • Neurogenic effect of b-amyloid peptide in the development of neural stem cells
    • Lopez-Toledano MA and Shelanski MI. Neurogenic effect of b-amyloid peptide in the development of neural stem cells. J Neurosci 24(23):5439-5444 (2004).
    • (2004) J Neurosci , vol.24 , Issue.23 , pp. 5439-5444
    • Lopez-Toledano, M.A.1    Shelanski, M.I.2
  • 57
    • 0034831233 scopus 로고    scopus 로고
    • The protein kinase Cdk5. Structural aspects, roles in neurogenesis and involvement in Alzheimer's pathology
    • Maccioni RB, Otth C, Concha II, Munoz JP. The protein kinase Cdk5. Structural aspects, roles in neurogenesis and involvement in Alzheimer's pathology. Eur J Biochem 268(6):1518-27 (2001).
    • (2001) Eur J Biochem , vol.268 , Issue.6 , pp. 1518-1527
    • Maccioni, R.B.1    Otth, C.2    Concha, I.I.3    Munoz, J.P.4
  • 58
    • 0032859938 scopus 로고    scopus 로고
    • Inhibition of tau phosphorylating protein kinase cdk5 prevents beta-amyloidinduced neuronal death
    • Alvarez A, Toro R, Caceres A, Maccioni RB. Inhibition of tau phosphorylating protein kinase cdk5 prevents beta-amyloidinduced neuronal death. FEBS Lett 459(3):421-426 (1999).
    • (1999) FEBS Lett , vol.459 , Issue.3 , pp. 421-426
    • Alvarez, A.1    Toro, R.2    Caceres, A.3    Maccioni, R.B.4
  • 59
    • 3342908640 scopus 로고    scopus 로고
    • Beta-amyloid peptide at sublethal concentrations downregulates brain-derived neurotrophic factor functions in cultured cortical neurons
    • Tong L, Balazs T, Thornton PL and Cotman CW. Beta-amyloid peptide at sublethal concentrations downregulates brain-derived neurotrophic factor functions in cultured cortical neurons. J Neurosci 24(30):6799-809 (2004).
    • (2004) J Neurosci , vol.24 , Issue.30 , pp. 6799-6809
    • Tong, L.1    Balazs, T.2    Thornton, P.L.3    Cotman, C.W.4
  • 60
    • 0041355557 scopus 로고    scopus 로고
    • Notch and Presenelin: Regulated intramembrane proteolysis links development and degeneration
    • Selkoe D, and Kopan R. Notch and Presenelin: Regulated intramembrane proteolysis links development and degeneration. Annu Rev Neurosci 26:565-597 (2003).
    • (2003) Annu Rev Neurosci , vol.26 , pp. 565-597
    • Selkoe, D.1    Kopan, R.2
  • 62
    • 0035839591 scopus 로고    scopus 로고
    • Notch1 and amyloid precursor protein are competitive substrates for presenilin1-dependent gamma-secretase cleavage
    • Berezovska O, Jack C, Deng A, Gastineau N, Rebeck Gw, and Hyman BT. Notch1 and amyloid precursor protein are competitive substrates for presenilin1-dependent gamma-secretase cleavage. J Biol Chem 276(32):300018-23 (2001).
    • (2001) J Biol Chem , vol.276 , Issue.32 , pp. 300018-300023
    • Berezovska, O.1    Jack, C.2    Deng, A.3    Gastineau, N.4    Gw, R.5    Hyman, B.T.6
  • 63
    • 21244476031 scopus 로고    scopus 로고
    • Perturbed neurogenesis in the adult hippocampus associated with Presenilin-1 A246E mutation
    • Chevallier NL, Soriano S, Kang DE, Masliah E, Hu G, and Koo EH. Perturbed neurogenesis in the adult hippocampus associated with Presenilin-1 A246E mutation. Neurobiol 167(1):151-159 (2005).
    • (2005) Neurobiol , vol.167 , Issue.1 , pp. 151-159
    • Chevallier, N.L.1    Soriano, S.2    Kang, D.E.3    Masliah, E.4    Hu, G.5    Koo, E.H.6
  • 64
    • 0033945494 scopus 로고    scopus 로고
    • Presenilin-1 regulates neuronal differentiation during neurogenesis
    • Handler M, Yang X and Shen J. Presenilin-1 regulates neuronal differentiation during neurogenesis. Devlopment 127:2593-2606 (2000).
    • (2000) Devlopment , vol.127 , pp. 2593-2606
    • Handler, M.1    Yang, X.2    Shen, J.3
  • 67
    • 0036434304 scopus 로고    scopus 로고
    • Suppression of insult-induced neurogenesis in adult rat brain by brain-derived neurotrophic factor
    • Larsson E, Mandel RJ, Klein RL, Muzyczka N, Lindvall O and Kokaia Z. Suppression of insult-induced neurogenesis in adult rat brain by brain-derived neurotrophic factor. Exp Neurol 177(1):1-8. (2002).
    • (2002) Exp Neurol , vol.177 , Issue.1 , pp. 1-8
    • Larsson, E.1    Mandel, R.J.2    Klein, R.L.3    Muzyczka, N.4    Lindvall, O.5    Kokaia, Z.6
  • 68
    • 0034255042 scopus 로고    scopus 로고
    • BDNF protects the neonatal brain from hypoxic-ischemic injury in vivo via the ERK pathway
    • Han BH and Holtzman DM. BDNF protects the neonatal brain from hypoxic-ischemic injury in vivo via the ERK pathway. J Neurosci 20(15):5775-5761 (2000).
    • (2000) J Neurosci , vol.20 , Issue.15 , pp. 5775-15761
    • Han, B.H.1    Holtzman, D.M.2
  • 69
    • 0036735783 scopus 로고    scopus 로고
    • Irradiation induces neural precursor-cell dysfunction
    • Monje ML, Mizumatsu S, Fike JR, and Palmer TD. Irradiation induces neural precursor-cell dysfunction. Nat Med 8(9):955-62 (2002).
    • (2002) Nat Med , vol.8 , Issue.9 , pp. 955-962
    • Monje, M.L.1    Mizumatsu, S.2    Fike, J.R.3    Palmer, T.D.4
  • 70
    • 0036522968 scopus 로고    scopus 로고
    • Adult rodent neurogenic regions: The ventricular subependyma contains neural stem cells, but the dentate gyrus contains restricted progenitors
    • Seaberg RM and van der Kooy D. Adult rodent neurogenic regions: the ventricular subependyma contains neural stem cells, but the dentate gyrus contains restricted progenitors. J Neurosci 22:1784-1793 (2002).
    • (2002) J Neurosci , vol.22 , pp. 1784-1793
    • Seaberg, R.M.1    Van Der Kooy, D.2
  • 72
    • 0036892118 scopus 로고    scopus 로고
    • Binge ethanol exposure decreases neurogenesis in adult rat hippocampus
    • Nixon K and Crews FT. Binge ethanol exposure decreases neurogenesis in adult rat hippocampus. J Neurochem 83(5):1087-1093 (2002).
    • (2002) J Neurochem , vol.83 , Issue.5 , pp. 1087-1093
    • Nixon, K.1    Crews, F.T.2
  • 73
    • 0037692850 scopus 로고    scopus 로고
    • Chronic AMPA potentiator (LY451646) treatment increases cell proliferation in adult rat hippocampus
    • Bai F, Bergeron M, Nelson DL. Chronic AMPA potentiator (LY451646) treatment increases cell proliferation in adult rat hippocampus. Neuropharmacology 44(8):1013-21 (2003).
    • (2003) Neuropharmacology , vol.44 , Issue.8 , pp. 1013-1021
    • Bai, F.1    Bergeron, M.2    Nelson, D.L.3
  • 75
    • 0033051299 scopus 로고    scopus 로고
    • Depletion in serotonin decreases neurogenesis in the dentate gyrus and the subventricular zone of adult rats
    • Brezun JM and Daszuta A. Depletion in serotonin decreases neurogenesis in the dentate gyrus and the subventricular zone of adult rats. Neurosci 89(4):999-1002 (1999).
    • (1999) Neurosci , vol.89 , Issue.4 , pp. 999-1002
    • Brezun, J.M.1    Daszuta, A.2
  • 76
    • 0036358623 scopus 로고    scopus 로고
    • Disruption of neurogenesis in the subventricular zone of adult mice, and in human cortical neuronal precursor cells in culture, by amyloid beta-peptide: Implications for the pathogenesis of Alzheimer's disease
    • Haughey NJ, Liu D, Nath A, Borchard AC, Mattson MP. Disruption of neurogenesis in the subventricular zone of adult mice, and in human cortical neuronal precursor cells in culture, by amyloid beta-peptide: implications for the pathogenesis of Alzheimer's disease. Neuromolec Med 1(2):125-135 (2002).
    • (2002) Neuromolec Med , vol.1 , Issue.2 , pp. 125-135
    • Haughey, N.J.1    Liu, D.2    Nath, A.3    Borchard, A.C.4    Mattson, M.P.5
  • 77
    • 0028364703 scopus 로고
    • Adult neurogenesis is regulated by adrenal steroids in the dentate gyrus
    • Cameron HA and Gould E. Adult neurogenesis is regulated by adrenal steroids in the dentate gyrus. Neurosci 61(2):203-209 (1994).
    • (1994) Neurosci , vol.61 , Issue.2 , pp. 203-209
    • Cameron, H.A.1    Gould, E.2
  • 78
    • 0034754052 scopus 로고    scopus 로고
    • A nitric oxide donor induces neurogenesis and reduces functional deficits after stroke in rats
    • Zhang R, Zhang L, Zhang Z, Wang Y, Lu M, Lapointe M, Chopp M. A nitric oxide donor induces neurogenesis and reduces functional deficits after stroke in rats. Ann Neurol 50(5):602-611 (2001).
    • (2001) Ann Neurol , vol.50 , Issue.5 , pp. 602-611
    • Zhang, R.1    Zhang, L.2    Zhang, Z.3    Wang, Y.4    Lu, M.5    Lapointe, M.6    Chopp, M.7
  • 79
    • 0030937293 scopus 로고    scopus 로고
    • More hippocampal neurons in adult mice living in an enriched environment
    • Kempermann G, Kuhn HG, and Gage FH. More hippocampal neurons in adult mice living in an enriched environment. Nature 386:49395 (1997).
    • (1997) Nature , vol.386 , pp. 49395
    • Kempermann, G.1    Kuhn, H.G.2    Gage, F.H.3
  • 80
    • 15544370150 scopus 로고    scopus 로고
    • Adult neurogenesis: From precursors to network and physiology
    • Abrous DN, Koehl M and Le Moal M. Adult neurogenesis: from precursors to network and physiology. Physiol Rev 85:523-569 (2005).
    • (2005) Physiol Rev , vol.85 , pp. 523-569
    • Abrous, D.N.1    Koehl, M.2    Le Moal, M.3
  • 81
    • 0042668324 scopus 로고    scopus 로고
    • Production of new cells in the rat dentate gyrus over the lifespan: Relation to cognitive decline
    • Bizon JL and Gallagher M. Production of new cells in the rat dentate gyrus over the lifespan: relation to cognitive decline. Eur J Neurosci 18(1):215-219 (2003).
    • (2003) Eur J Neurosci , vol.18 , Issue.1 , pp. 215-219
    • Bizon, J.L.1    Gallagher, M.2
  • 82
    • 0037471433 scopus 로고    scopus 로고
    • Hippocampal cell genesis does not correlate with spatial learning ability in aged rats
    • Merrill DA, Karim R, Darraq M, Chiba AA and Tuszynski MH. Hippocampal cell genesis does not correlate with spatial learning ability in aged rats. J Comp Neurol 459(2):201-207 (2003).
    • (2003) J Comp Neurol , vol.459 , Issue.2 , pp. 201-207
    • Merrill, D.A.1    Karim, R.2    Darraq, M.3    Chiba, A.A.4    Tuszynski, M.H.5
  • 83
    • 0344198502 scopus 로고    scopus 로고
    • Spatial memory performances of aged rats in the water maze predict levels of hippocampal neurogenesis
    • USA
    • Drapeau E, Mayo W, Aurousseau C, Le Moal M, Piazza PV and Abrous DN. Spatial memory performances of aged rats in the water maze predict levels of hippocampal neurogenesis. Proc Natl Acad Sci USA 100(24):14385-90 (2003).
    • (2003) Proc Natl Acad Sci , vol.100 , Issue.24 , pp. 14385-14390
    • Drapeau, E.1    Mayo, W.2    Aurousseau, C.3    Le Moal, M.4    Piazza, P.V.5    Abrous, D.N.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.