Indole- and indoline-based kainate analogues with antagonist activity at ionotropic glutamate receptors

Bioorganic and Medicinal Chemistry Letters

Volumn 15, Issue 17, 2005, Pages 3942-3947

  Shou, Xiaohong ^a   Miledi, Ricardo ^b   Chamberlin, A Richard ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Agonist; AMPA; Antagonist; DNQX; Glutamate receptor; iGluR2; Indole; Indoline; Kainic acid

Indexed keywords

AMPA RECEPTOR; IONOTROPIC RECEPTOR ANTAGONIST; KAINIC ACID DERIVATIVE; KAINIC ACID RECEPTOR;

ANIMAL CELL; ARTICLE; CONFORMATION; CONTROLLED STUDY; FEMALE; MOLECULAR MODEL; NONHUMAN; OOCYTE; RAT; X RAY;

ANIMALS; CEREBRAL CORTEX; DRUG DESIGN; ELECTROPHYSIOLOGY; EXCITATORY AMINO ACID ANTAGONISTS; INDOLES; KAINIC ACID; MODELS, MOLECULAR; MUSCLE CONTRACTION; OOCYTES; RATS; RECEPTORS, GLUTAMATE; STRUCTURE-ACTIVITY RELATIONSHIP; TRANSFECTION; XENOPUS;

EID: 23244468487     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2005.05.098     Document Type: Article

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