Pharmacological properties of the potent epileptogenic amino acid dysiherbaine, a novel glutamate receptor agonist isolated from the marine sponge Dysidea herbacea

Journal of Pharmacology and Experimental Therapeutics

Volumn 296, Issue 2, 2001, Pages 650-658

  Sakai, Ryuichi ^a   Swanson, Geoffrey T ^b   Shimamoto, Keiko ^c   Green, Tim ^b   Contractor, Anis ^b   Ghetti, Andrea ^b   Tamura Horikawa, Yoshiko ^d   Oiwa, Chie ^a   Kamiya, Hisao ^a  

^a KITASATO UNIVERSITY   (Japan)

^b SALK INSTITUTE FOR BIOLOGICAL STUDIES   (United States)

^c SUNTORY INSTITUTE FOR BIOORGANIC RESEARCH   (Japan)

^d Biomedical Research   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

1 (4 AMINOPHENYL) 3,4 DIHYDRO 4 METHYL 3 METHYLCARBAMOYL 7,8 METHYLENEDIOXY 5H 2,3 BENZODIAZEPINE; 4 AMINOBUTYRIC ACID RECEPTOR; ALPHA AMINO 3 HYDROXY 5 METHYL 4 ISOXAZOLEPROPIONIC ACID; DYSIHERBAINE; GLUTAMATE RECEPTOR; GLUTAMATE RECEPTOR AGONIST; GLUTAMATE TRANSPORTER; KAINIC ACID; N METHYL DEXTRO ASPARTIC ACID; UNCLASSIFIED DRUG;

ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL TISSUE; AQUATIC FAUNA; ARTICLE; BINDING AFFINITY; CONTROLLED STUDY; CONVULSION; DRUG ACTIVITY; DRUG EFFECT; DRUG ISOLATION; DRUG MECHANISM; DRUG POTENCY; DRUG RECEPTOR BINDING; DRUG STRUCTURE; EPILEPTIC FOCUS; HIPPOCAMPUS; MALE; MARINE ENVIRONMENT; MEMBRANE CURRENT; MOUSE; NERVE CELL; NONHUMAN; PRIORITY JOURNAL; SYNAPTIC MEMBRANE;

ALANINE; AMINO ACID TRANSPORT SYSTEM X-AG; ANIMALS; ATP-BINDING CASSETTE TRANSPORTERS; BICYCLO COMPOUNDS, HETEROCYCLIC; CALCIUM; CELLS, CULTURED; CONVULSANTS; DIAGNOSTIC IMAGING; EXCITATORY AMINO ACID AGONISTS; INJECTIONS, INTRAVENTRICULAR; MALE; MICE; NEURONS; PORIFERA; RADIOLIGAND ASSAY; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, METABOTROPIC GLUTAMATE; SEIZURES; SYNAPTIC MEMBRANES;

EID: 0035144471     PISSN: 00223565     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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