메뉴 건너뛰기




Volumn 533, Issue 1-3, 2006, Pages 89-100

Prostanoids as pharmacological targets in COPD and asthma

Author keywords

Asthma; Chronic obstructive pulmonary disease; Isoprostanes; Prostanoid

Indexed keywords

ANTIASTHMATIC AGENT; INDOMETACIN; ISOPROSTANE; ISOPROSTANE DERIVATIVE; K117; K604; L 888607; OZAGREL; PHOSPHOLIPID; PROSTACYCLIN; PROSTAGLANDIN; PROSTAGLANDIN D2; PROSTAGLANDIN E2; PROSTAGLANDIN F2 ALPHA; PROSTAGLANDIN SYNTHASE; PROSTANOID; RAMATROBAN; REACTIVE OXYGEN METABOLITE; SERATRODAST; THROMBOXANE A2; THROMBOXANE A2 RECEPTOR BLOCKING AGENT; UNCLASSIFIED DRUG;

EID: 33644746168     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejphar.2005.12.058     Document Type: Review
Times cited : (85)

References (156)
  • 2
    • 0030060019 scopus 로고    scopus 로고
    • BAY u3405, a thromboxane A2 antagonist, reduces bronchial hyperresponsiveness in asthmatics
    • H. Aizawa, M. Shigyo, H. Nogami, T. Hirose, and N. Hara BAY u3405, a thromboxane A2 antagonist, reduces bronchial hyperresponsiveness in asthmatics Chest 109 1996 338 342
    • (1996) Chest , vol.109 , pp. 338-342
    • Aizawa, H.1    Shigyo, M.2    Nogami, H.3    Hirose, T.4    Hara, N.5
  • 3
    • 0032422786 scopus 로고    scopus 로고
    • Binding of YM158, a new dual antagonist for leukotriene D4 and thromboxane A2 receptors, to guinea pig lung membranes
    • Y. Arakida, K. Ohga, S. Kobayashi, M. Yokota, K. Miyata, T. Yamada, and K. Honda Binding of YM158, a new dual antagonist for leukotriene D4 and thromboxane A2 receptors, to guinea pig lung membranes Eur. J. Pharmacol. 362 1998 229 233
    • (1998) Eur. J. Pharmacol. , vol.362 , pp. 229-233
    • Arakida, Y.1    Ohga, K.2    Kobayashi, S.3    Yokota, M.4    Miyata, K.5    Yamada, T.6    Honda, K.7
  • 5
    • 0034066313 scopus 로고    scopus 로고
    • Effect of YM158, a dual lipid mediator antagonist, on immediate and late asthmatic responses, and on airway hyper-responsiveness in guinea pigs
    • Y. Arakida, K. Ohga, K. Suwa, Y. Okada, H. Morio, M. Yokota, K. Miyata, T. Yamada, and K. Honda Effect of YM158, a dual lipid mediator antagonist, on immediate and late asthmatic responses, and on airway hyper-responsiveness in guinea pigs Jpn. J. Pharmacol. 82 2000 287 294
    • (2000) Jpn. J. Pharmacol. , vol.82 , pp. 287-294
    • Arakida, Y.1    Ohga, K.2    Suwa, K.3    Okada, Y.4    Morio, H.5    Yokota, M.6    Miyata, K.7    Yamada, T.8    Honda, K.9
  • 7
    • 0024309982 scopus 로고
    • A novel anti-asthmatic quinone derivative, AA-2414 with a potent antagonistic activity against a variety of spasmogenic prostanoids
    • Y. Ashida, T. Matsumoto, H. Kuriki, M. Shiraishi, K. Kato, and S. Terao A novel anti-asthmatic quinone derivative, AA-2414 with a potent antagonistic activity against a variety of spasmogenic prostanoids Prostaglandins 38 1989 91 112
    • (1989) Prostaglandins , vol.38 , pp. 91-112
    • Ashida, Y.1    Matsumoto, T.2    Kuriki, H.3    Shiraishi, M.4    Kato, K.5    Terao, S.6
  • 8
    • 0027537870 scopus 로고
    • Identification of non-cyclooxygenase-derived prostanoid (F2-isoprostane) metabolites in human urine and plasma
    • J.A. Awad, J.D. Morrow, K. Takahashi, and L.J. Roberts II Identification of non-cyclooxygenase-derived prostanoid (F2-isoprostane) metabolites in human urine and plasma J. Biol. Chem. 268 1993 4161 4169
    • (1993) J. Biol. Chem. , vol.268 , pp. 4161-4169
    • Awad, J.A.1    Morrow, J.D.2    Takahashi, K.3    Roberts II, L.J.4
  • 9
    • 0036725342 scopus 로고    scopus 로고
    • Allergic rhinitis and its impact on asthma. in collaboration with the World Health Organization. Executive summary of the workshop report. 7-10 December 1999, Geneva, Switzerland
    • C. Bachert, P. van Cauwenberge, N. Khaltaev, and J. Bousquet Allergic rhinitis and its impact on asthma. In collaboration with the World Health Organization. Executive summary of the workshop report. 7-10 December 1999, Geneva, Switzerland Allergy 57 2002 841 855
    • (2002) Allergy , vol.57 , pp. 841-855
    • Bachert, C.1    Van Cauwenberge, P.2    Khaltaev, N.3    Bousquet, J.4
  • 10
    • 0033994635 scopus 로고    scopus 로고
    • Mechanisms in COPD: Differences from asthma
    • P.J. Barnes Mechanisms in COPD: differences from asthma Chest 117 2000 10S 14S
    • (2000) Chest , vol.117
    • Barnes, P.J.1
  • 11
    • 10644266789 scopus 로고    scopus 로고
    • Mediators of chronic obstructive pulmonary disease
    • P.J. Barnes Mediators of chronic obstructive pulmonary disease Pharmacol. Rev. 56 2004 515 548
    • (2004) Pharmacol. Rev. , vol.56 , pp. 515-548
    • Barnes, P.J.1
  • 12
    • 0032445151 scopus 로고    scopus 로고
    • Inflammatory mediators of asthma: An update
    • P.J. Barnes, K.F. Chung, and C.P. Page Inflammatory mediators of asthma: an update Pharmacol. Rev. 50 1998 515 596
    • (1998) Pharmacol. Rev. , vol.50 , pp. 515-596
    • Barnes, P.J.1    Chung, K.F.2    Page, C.P.3
  • 14
    • 0029134144 scopus 로고
    • Molecular cloning and characterization of the human prostanoid DP receptor
    • Y. Boie, N. Sawyer, D.M. Slipetz, K.M. Metters, and M. Abramovitz Molecular cloning and characterization of the human prostanoid DP receptor J. Biol. Chem. 270 1995 18910 18916
    • (1995) J. Biol. Chem. , vol.270 , pp. 18910-18916
    • Boie, Y.1    Sawyer, N.2    Slipetz, D.M.3    Metters, K.M.4    Abramovitz, M.5
  • 19
    • 0026604612 scopus 로고
    • Enhanced superoxide production by alveolar macrophages and air-space cells, airway inflammation, and alveolar macrophage density changes after segmental antigen bronchoprovocation in allergic subjects
    • W.J. Calhoun, H.E. Reed, D.R. Moest, and C.A. Stevens Enhanced superoxide production by alveolar macrophages and air-space cells, airway inflammation, and alveolar macrophage density changes after segmental antigen bronchoprovocation in allergic subjects Am. Rev. Respir. Dis. 145 1992 317 325
    • (1992) Am. Rev. Respir. Dis. , vol.145 , pp. 317-325
    • Calhoun, W.J.1    Reed, H.E.2    Moest, D.R.3    Stevens, C.A.4
  • 21
    • 0037033179 scopus 로고    scopus 로고
    • Design, synthesis and pharmacological evaluation of novel pyrazolo[3,4-b]thieno[2,3-d]pyridine acid derivatives: A new class of anti-inflammatory and anti-platelet agents
    • C.R. Cardoso, F.C. de Brito, K.C. da Silva, A.L. de Miranda, C.A. Fraga, and E.J. Barreiro Design, synthesis and pharmacological evaluation of novel pyrazolo[3,4-b]thieno[2,3-d]pyridine acid derivatives: a new class of anti-inflammatory and anti-platelet agents Bioorg. Med. Chem. Lett. 12 2002 9 12
    • (2002) Bioorg. Med. Chem. Lett. , vol.12 , pp. 9-12
    • Cardoso, C.R.1    De Brito, F.C.2    Da Silva, K.C.3    De Miranda, A.L.4    Fraga, C.A.5    Barreiro, E.J.6
  • 23
    • 0036044999 scopus 로고    scopus 로고
    • Management of asthma exacerbations
    • M.S. Chesnutt Management of asthma exacerbations Clin. Cornerstone 4 2002 1 17
    • (2002) Clin. Cornerstone , vol.4 , pp. 1-17
    • Chesnutt, M.S.1
  • 24
    • 0024592289 scopus 로고
    • Prostanoid-induced contraction of human bronchial smooth muscle is mediated by TP-receptors
    • R.A. Coleman, and R.L. Sheldrick Prostanoid-induced contraction of human bronchial smooth muscle is mediated by TP-receptors Br. J. Pharmacol. 96 1989 688 692
    • (1989) Br. J. Pharmacol. , vol.96 , pp. 688-692
    • Coleman, R.A.1    Sheldrick, R.L.2
  • 25
    • 0028183018 scopus 로고
    • International Union of Pharmacology classification of prostanoid receptors: Properties, distribution, and structure of the receptors and their subtypes
    • R.A. Coleman, W.L. Smith, and S. Narumiya International Union of Pharmacology classification of prostanoid receptors: properties, distribution, and structure of the receptors and their subtypes Pharmacol. Rev. 46 1994 205 229
    • (1994) Pharmacol. Rev. , vol.46 , pp. 205-229
    • Coleman, R.A.1    Smith, W.L.2    Narumiya, S.3
  • 26
    • 14444268051 scopus 로고    scopus 로고
    • Enhanced thromboxane biosynthesis in patients with chronic obstructive pulmonary disease. the Chronic Obstructive Bronchitis and Haemostasis Study Group
    • G. Davi, S. Basili, M. Vieri, F. Cipollone, S. Santarone, C. Alessandri, P. Gazzaniga, C. Cordova, and F. Violi Enhanced thromboxane biosynthesis in patients with chronic obstructive pulmonary disease. The Chronic Obstructive Bronchitis and Haemostasis Study Group Am. J. Respir. Crit. Care Med. 156 1997 1794 1799
    • (1997) Am. J. Respir. Crit. Care Med. , vol.156 , pp. 1794-1799
    • Davi, G.1    Basili, S.2    Vieri, M.3    Cipollone, F.4    Santarone, S.5    Alessandri, C.6    Gazzaniga, P.7    Cordova, C.8    Violi, F.9
  • 29
    • 0030614835 scopus 로고    scopus 로고
    • Thromboxane A2 and related prostaglandins in airways
    • P. Devillier, and G. Bessard Thromboxane A2 and related prostaglandins in airways Fundam. Clin. Pharmacol. 11 1997 2 18
    • (1997) Fundam. Clin. Pharmacol. , vol.11 , pp. 2-18
    • Devillier, P.1    Bessard, G.2
  • 33
    • 0027339671 scopus 로고
    • Thromboxane A2 stimulated signal transduction in vascular smooth muscle
    • G.W. Dorn II, and M.W. Becker Thromboxane A2 stimulated signal transduction in vascular smooth muscle J. Pharmacol. Exp. Ther. 265 1993 447 456
    • (1993) J. Pharmacol. Exp. Ther. , vol.265 , pp. 447-456
    • Dorn II, G.W.1    Becker, M.W.2
  • 36
    • 0035723661 scopus 로고    scopus 로고
    • Assessment of oxidant stress in allergic asthma by measurement of the major urinary metabolite of F2-isoprostane, 15-F2t-IsoP (8-iso-PGF2alpha)
    • R. Dworski, L.J. Roberts II, J.J. Murray, J.D. Morrow, T.V. Hartert, and J.R. Sheller Assessment of oxidant stress in allergic asthma by measurement of the major urinary metabolite of F2-isoprostane, 15-F2t-IsoP (8-iso-PGF2alpha) Clin. Exp. Allergy 31 2001 387 390
    • (2001) Clin. Exp. Allergy , vol.31 , pp. 387-390
    • Dworski, R.1    Roberts II, L.J.2    Murray, J.J.3    Morrow, J.D.4    Hartert, T.V.5    Sheller, J.R.6
  • 37
    • 0024472734 scopus 로고
    • Prostaglandin D2 causes accumulation of eosinophils in the lumen of the dog trachea
    • D.L. Emery, T.D. Djokic, P.D. Graf, and J.A. Nadel Prostaglandin D2 causes accumulation of eosinophils in the lumen of the dog trachea J. Appl. Physiol. 67 1989 959 962
    • (1989) J. Appl. Physiol. , vol.67 , pp. 959-962
    • Emery, D.L.1    Djokic, T.D.2    Graf, P.D.3    Nadel, J.A.4
  • 38
    • 0021742894 scopus 로고
    • Modulation of the bronchomotor effects of chemical mediators by prostaglandin F2 alpha in asthmatic subjects
    • J.E. Fish, L.S. Jameson, A. Albright, and P.S. Norman Modulation of the bronchomotor effects of chemical mediators by prostaglandin F2 alpha in asthmatic subjects Am. Rev. Respir. Dis. 130 1984 571 574
    • (1984) Am. Rev. Respir. Dis. , vol.130 , pp. 571-574
    • Fish, J.E.1    Jameson, L.S.2    Albright, A.3    Norman, P.S.4
  • 39
    • 0035833502 scopus 로고    scopus 로고
    • The coxibs, selective inhibitors of cyclooxygenase-2
    • G.A. FitzGerald, and C. Patrono The coxibs, selective inhibitors of cyclooxygenase-2 N. Engl. J. Med. 345 2001 433 442
    • (2001) N. Engl. J. Med. , vol.345 , pp. 433-442
    • Fitzgerald, G.A.1    Patrono, C.2
  • 40
    • 0026391524 scopus 로고
    • The thromboxane receptor antagonist BAY u3405 reverses prostaglandin D2 (PGD2)-induced bronchoconstriction in the anaesthetised guinea pig
    • H.P. Francis, T.G. Morris, A.M. Thompson, U.P. Patel, and P.J. Gardiner The thromboxane receptor antagonist BAY u3405 reverses prostaglandin D2 (PGD2)-induced bronchoconstriction in the anaesthetised guinea pig Ann. N.Y. Acad. Sci. 629 1991 399 401
    • (1991) Ann. N.Y. Acad. Sci. , vol.629 , pp. 399-401
    • Francis, H.P.1    Morris, T.G.2    Thompson, A.M.3    Patel, U.P.4    Gardiner, P.J.5
  • 41
    • 0023024261 scopus 로고
    • Effects of a thromboxane synthetase inhibitor (OKY-046) and a lipoxygenase inhibitor (AA-861) on bronchial responsiveness to acetylcholine in asthmatic subjects
    • M. Fujimura, F. Sasaki, Y. Nakatsumi, Y. Takahashi, S. Hifumi, K. Taga, J. Mifune, T. Tanaka, and T. Matsuda Effects of a thromboxane synthetase inhibitor (OKY-046) and a lipoxygenase inhibitor (AA-861) on bronchial responsiveness to acetylcholine in asthmatic subjects Thorax 41 1986 955 959
    • (1986) Thorax , vol.41 , pp. 955-959
    • Fujimura, M.1    Sasaki, F.2    Nakatsumi, Y.3    Takahashi, Y.4    Hifumi, S.5    Taga, K.6    Mifune, J.7    Tanaka, T.8    Matsuda, T.9
  • 42
    • 0023946301 scopus 로고
    • Secondary release of thromboxane A2 in aerosol leukotriene C4-induced bronchoconstriction in guinea pigs
    • M. Fujimura, Y. Miyake, K. Uotani, K. Kanamori, and T. Matsuda Secondary release of thromboxane A2 in aerosol leukotriene C4-induced bronchoconstriction in guinea pigs Prostaglandins 35 1988 427 435
    • (1988) Prostaglandins , vol.35 , pp. 427-435
    • Fujimura, M.1    Miyake, Y.2    Uotani, K.3    Kanamori, K.4    Matsuda, T.5
  • 43
    • 0025106514 scopus 로고
    • Effects of aerosol administration of a thromboxane synthetase inhibitor (OKY-046) on bronchial responsiveness to acetylcholine in asthmatic subjects
    • M. Fujimura, S. Nishioka, I. Kumabashiri, T. Matsuda, and J. Mifune Effects of aerosol administration of a thromboxane synthetase inhibitor (OKY-046) on bronchial responsiveness to acetylcholine in asthmatic subjects Chest 98 1990 276 279
    • (1990) Chest , vol.98 , pp. 276-279
    • Fujimura, M.1    Nishioka, S.2    Kumabashiri, I.3    Matsuda, T.4    Mifune, J.5
  • 44
    • 0025018182 scopus 로고
    • Attenuating effect of a thromboxane synthetase inhibitor (OKY-046) on bronchial responsiveness to methacholine is specific to bronchial asthma
    • M. Fujimura, S. Sakamoto, and T. Matsuda Attenuating effect of a thromboxane synthetase inhibitor (OKY-046) on bronchial responsiveness to methacholine is specific to bronchial asthma Chest 98 1990 656 660
    • (1990) Chest , vol.98 , pp. 656-660
    • Fujimura, M.1    Sakamoto, S.2    Matsuda, T.3
  • 46
    • 0022648757 scopus 로고
    • Characterization of prostanoid relaxant/inhibitory receptors (psi) using a highly selective agonist, TR4979
    • P.J. Gardiner Characterization of prostanoid relaxant/inhibitory receptors (psi) using a highly selective agonist, TR4979 Br. J. Pharmacol. 87 1986 45 56
    • (1986) Br. J. Pharmacol. , vol.87 , pp. 45-56
    • Gardiner, P.J.1
  • 48
    • 0033623954 scopus 로고    scopus 로고
    • Second messengers, ion channels and pharmacology of airway smooth muscle
    • I.P. Hall Second messengers, ion channels and pharmacology of airway smooth muscle Eur. Respir. J. 15 2000 1120 1127
    • (2000) Eur. Respir. J. , vol.15 , pp. 1120-1127
    • Hall, I.P.1
  • 49
    • 0016748441 scopus 로고
    • Thromboxanes: A new group of biologically active compounds derived from prostaglandin endoperoxides
    • M. Hamberg, J. Svensson, and B. Samuelsson Thromboxanes: a new group of biologically active compounds derived from prostaglandin endoperoxides Proc. Natl. Acad. Sci. U. S. A. 72 1975 2994 2998
    • (1975) Proc. Natl. Acad. Sci. U. S. A. , vol.72 , pp. 2994-2998
    • Hamberg, M.1    Svensson, J.2    Samuelsson, B.3
  • 50
    • 0021141316 scopus 로고
    • The bronchoconstrictor effect of inhaled prostaglandin D2 in normal and asthmatic men
    • C.C. Hardy, C. Robinson, A.E. Tattersfield, and S.T. Holgate The bronchoconstrictor effect of inhaled prostaglandin D2 in normal and asthmatic men N. Engl. J. Med. 311 1984 209 213
    • (1984) N. Engl. J. Med. , vol.311 , pp. 209-213
    • Hardy, C.C.1    Robinson, C.2    Tattersfield, A.E.3    Holgate, S.T.4
  • 51
    • 4444262310 scopus 로고    scopus 로고
    • Pharmacology and signaling of prostaglandin receptors: Multiple roles in inflammation and immune modulation
    • A.N. Hata, and R.M. Breyer Pharmacology and signaling of prostaglandin receptors: multiple roles in inflammation and immune modulation Pharmacol. Ther. 103 2004 147 166
    • (2004) Pharmacol. Ther. , vol.103 , pp. 147-166
    • Hata, A.N.1    Breyer, R.M.2
  • 52
    • 14944363741 scopus 로고    scopus 로고
    • Structural determinants of arylacetic acid nonsteroidal anti-inflammatory drugs necessary for binding and activation of the prostaglandin D2 receptor CRTH2
    • A.N. Hata, T.P. Lybrand, L.J. Marnett, and R.M. Breyer Structural determinants of arylacetic acid nonsteroidal anti-inflammatory drugs necessary for binding and activation of the prostaglandin D2 receptor CRTH2 Mol. Pharmacol. 67 2005 640 647
    • (2005) Mol. Pharmacol. , vol.67 , pp. 640-647
    • Hata, A.N.1    Lybrand, T.P.2    Marnett, L.J.3    Breyer, R.M.4
  • 53
  • 54
    • 0020617819 scopus 로고
    • The source of thromboxane and prostaglandins in experimental inflammation
    • G.A. Higgs, S. Moncada, J.A. Salmon, and K. Seager The source of thromboxane and prostaglandins in experimental inflammation Br. J. Pharmacol. 79 1983 863 868
    • (1983) Br. J. Pharmacol. , vol.79 , pp. 863-868
    • Higgs, G.A.1    Moncada, S.2    Salmon, J.A.3    Seager, K.4
  • 56
    • 0036467346 scopus 로고    scopus 로고
    • Cutting edge: Agonistic effect of indomethacin on a prostaglandin D2 receptor, CRTH2
    • H. Hirai, K. Tanaka, S. Takano, M. Ichimasa, M. Nakamura, and K. Nagata Cutting edge: agonistic effect of indomethacin on a prostaglandin D2 receptor, CRTH2 J. Immunol. 168 2002 981 985
    • (2002) J. Immunol. , vol.168 , pp. 981-985
    • Hirai, H.1    Tanaka, K.2    Takano, S.3    Ichimasa, M.4    Nakamura, M.5    Nagata, K.6
  • 58
    • 0029664751 scopus 로고    scopus 로고
    • Two thromboxane A2 receptor isoforms in human platelets. Opposite coupling to adenylyl cyclase with different sensitivity to Arg60 to Leu mutation
    • T. Hirata, F. Ushikubi, A. Kakizuka, M. Okuma, and S. Narumiya Two thromboxane A2 receptor isoforms in human platelets. Opposite coupling to adenylyl cyclase with different sensitivity to Arg60 to Leu mutation J. Clin. Invest. 97 1996 949 956
    • (1996) J. Clin. Invest. , vol.97 , pp. 949-956
    • Hirata, T.1    Ushikubi, F.2    Kakizuka, A.3    Okuma, M.4    Narumiya, S.5
  • 60
    • 0026101313 scopus 로고
    • The effect of a specific thromboxane A2 antagonist, AA-2414 on airway hyperresponsiveness induced by ozone exposure in dogs
    • T. Imai, M. Adachi, K. Idaira, T. Suganuma, T. Takahashi, H. Yamaguchi, C. Saito, M. Maeda, and A. Tsuji The effect of a specific thromboxane A2 antagonist, AA-2414 on airway hyperresponsiveness induced by ozone exposure in dogs Arerugi 40 1991 28 36
    • (1991) Arerugi , vol.40 , pp. 28-36
    • Imai, T.1    Adachi, M.2    Idaira, K.3    Suganuma, T.4    Takahashi, T.5    Yamaguchi, H.6    Saito, C.7    Maeda, M.8    Tsuji, A.9
  • 61
    • 1842575928 scopus 로고    scopus 로고
    • Involvement of thromboxane A2 (TXA2) in the early stages of oleic acid-induced lung injury and the preventive effect of ozagrel, a TXA2 synthase inhibitor, in guinea-pigs
    • Y. Ishitsuka, H. Moriuchi, K. Hatamoto, C. Yang, J. Takase, S. Golbidi, M. Irikura, and T. Irie Involvement of thromboxane A2 (TXA2) in the early stages of oleic acid-induced lung injury and the preventive effect of ozagrel, a TXA2 synthase inhibitor, in guinea-pigs J. Pharm. Pharmacol. 56 2004 513 520
    • (2004) J. Pharm. Pharmacol. , vol.56 , pp. 513-520
    • Ishitsuka, Y.1    Moriuchi, H.2    Hatamoto, K.3    Yang, C.4    Takase, J.5    Golbidi, S.6    Irikura, M.7    Irie, T.8
  • 62
    • 3042705826 scopus 로고    scopus 로고
    • Ramatroban (BAY u 3405): A novel dual antagonist of TXA2 receptor and CRTh2, a newly identified prostaglandin D2 receptor
    • T. Ishizuka, T. Matsui, Y. Okamoto, A. Ohta, and M. Shichijo Ramatroban (BAY u 3405): a novel dual antagonist of TXA2 receptor and CRTh2, a newly identified prostaglandin D2 receptor Cardiovasc. Drug Rev. 22 2004 71 90
    • (2004) Cardiovasc. Drug Rev. , vol.22 , pp. 71-90
    • Ishizuka, T.1    Matsui, T.2    Okamoto, Y.3    Ohta, A.4    Shichijo, M.5
  • 63
    • 0031881630 scopus 로고    scopus 로고
    • Clinical effects of sodium ozagrel and urokinase in patients with acute cerebral infarction in the territory of the internal carotid artery
    • H. Itoh, K. Yamatani, N. Oshida, M. Shioi, M. Takaba, H. Kamiyama, and M. Itoh Clinical effects of sodium ozagrel and urokinase in patients with acute cerebral infarction in the territory of the internal carotid artery No To Shinkei 50 1998 147 155
    • (1998) No to Shinkei , vol.50 , pp. 147-155
    • Itoh, H.1    Yamatani, K.2    Oshida, N.3    Shioi, M.4    Takaba, M.5    Kamiyama, H.6    Itoh, M.7
  • 64
    • 0029111862 scopus 로고
    • Effect of a selective thromboxane A2 receptor antagonist BAY u3405 on antigen-, leukotriene C4- and leukotriene D4-induced bronchoconstriction in guinea pigs
    • I. Iwamoto, T. Umibe, H. Nakajima, and S. Yoshida Effect of a selective thromboxane A2 receptor antagonist BAY u3405 on antigen-, leukotriene C4- and leukotriene D4-induced bronchoconstriction in guinea pigs Int. Arch. Allergy Immunol. 108 1995 68 73
    • (1995) Int. Arch. Allergy Immunol. , vol.108 , pp. 68-73
    • Iwamoto, I.1    Umibe, T.2    Nakajima, H.3    Yoshida, S.4
  • 65
    • 0037111429 scopus 로고    scopus 로고
    • A key role for prostaglandin I2 in limiting lung mucosal Th2, but not Th1, responses to inhaled allergen
    • Z. Jaffar, K.S. Wan, and K. Roberts A key role for prostaglandin I2 in limiting lung mucosal Th2, but not Th1, responses to inhaled allergen J. Immunol. 169 2002 5997 6004
    • (2002) J. Immunol. , vol.169 , pp. 5997-6004
    • Jaffar, Z.1    Wan, K.S.2    Roberts, K.3
  • 66
    • 0034990522 scopus 로고    scopus 로고
    • Isoprostanes: An overview and putative roles in pulmonary pathophysiology
    • L.J. Janssen Isoprostanes: an overview and putative roles in pulmonary pathophysiology Am. J. Physiol., Lung Cell Mol. Physiol. 280 2001 L1067 L1082
    • (2001) Am. J. Physiol., Lung Cell Mol. Physiol. , vol.280
    • Janssen, L.J.1
  • 68
    • 0035141402 scopus 로고    scopus 로고
    • Vasoconstrictor actions of isoprostanes via tyrosine kinase and Rho kinase in human and canine pulmonary vascular smooth muscles
    • L.J. Janssen, M. Premji, S. Netherton, J. Coruzzi, H. Lu-Chao, and P.G. Cox Vasoconstrictor actions of isoprostanes via tyrosine kinase and Rho kinase in human and canine pulmonary vascular smooth muscles Br. J. Pharmacol. 132 2001 127 134
    • (2001) Br. J. Pharmacol. , vol.132 , pp. 127-134
    • Janssen, L.J.1    Premji, M.2    Netherton, S.3    Coruzzi, J.4    Lu-Chao, H.5    Cox, P.G.6
  • 70
    • 0031954369 scopus 로고    scopus 로고
    • Structural and inflammatory changes in COPD: A comparison with asthma
    • P.K. Jeffery Structural and inflammatory changes in COPD: a comparison with asthma Thorax 53 1998 129 136
    • (1998) Thorax , vol.53 , pp. 129-136
    • Jeffery, P.K.1
  • 71
    • 0032504237 scopus 로고    scopus 로고
    • G protein-coupled receptors. I. Diversity of receptor-ligand interactions
    • T.H. Ji, M. Grossmann, and I. Ji G protein-coupled receptors. I. Diversity of receptor-ligand interactions J. Biol. Chem. 273 1998 17299 17302
    • (1998) J. Biol. Chem. , vol.273 , pp. 17299-17302
    • Ji, T.H.1    Grossmann, M.2    Ji, I.3
  • 72
    • 0026874477 scopus 로고
    • Effect of an inhaled thromboxane mimetic (U46619) on airway function in human subjects
    • G.L. Jones, H.G. Saroea, R.M. Watson, and P.M. O'Byrne Effect of an inhaled thromboxane mimetic (U46619) on airway function in human subjects Am. Rev. Respir. Dis. 145 1992 1270 1274
    • (1992) Am. Rev. Respir. Dis. , vol.145 , pp. 1270-1274
    • Jones, G.L.1    Saroea, H.G.2    Watson, R.M.3    O'Byrne, P.M.4
  • 75
    • 0030610439 scopus 로고    scopus 로고
    • The human thromboxane A2 receptor alpha isoform (TP alpha) functionally couples to the G proteins Gq and G11 in vivo and is activated by the isoprostane 8-epi prostaglandin F2 alpha
    • B.T. Kinsella, D.J. O'Mahony, and G.A. Fitzgerald The human thromboxane A2 receptor alpha isoform (TP alpha) functionally couples to the G proteins Gq and G11 in vivo and is activated by the isoprostane 8-epi prostaglandin F2 alpha J. Pharmacol. Exp. Ther. 281 1997 957 964
    • (1997) J. Pharmacol. Exp. Ther. , vol.281 , pp. 957-964
    • Kinsella, B.T.1    O'Mahony, D.J.2    Fitzgerald, G.A.3
  • 76
    • 0036669383 scopus 로고    scopus 로고
    • Function of prostanoid receptors: Studies on knockout mice
    • T. Kobayashi, and S. Narumiya Function of prostanoid receptors: studies on knockout mice Prostaglandins Other Lipid Mediat. 68-69 2002 557 573
    • (2002) Prostaglandins Other Lipid Mediat. , vol.68-69 , pp. 557-573
    • Kobayashi, T.1    Narumiya, S.2
  • 78
    • 0028787037 scopus 로고
    • Synthesis of a novel dual inhibitor of thromboxane A2 synthetase and 5-lipoxygenase (E3040) via the direct coupling reaction of hydroquinone with 3-pyridinecarboxaldehyde
    • Y. Komatsu, and N. Minami Synthesis of a novel dual inhibitor of thromboxane A2 synthetase and 5-lipoxygenase (E3040) via the direct coupling reaction of hydroquinone with 3-pyridinecarboxaldehyde Chem. Pharm. Bull. (Tokyo) 43 1995 1614 1616
    • (1995) Chem. Pharm. Bull. (Tokyo) , vol.43 , pp. 1614-1616
    • Komatsu, Y.1    Minami, N.2
  • 79
    • 0026644731 scopus 로고
    • Urinary excretion of leukotriene E4 and 11-dehydro-thromboxane B2 in response to bronchial provocations with allergen, aspirin, leukotriene D4, and histamine in asthmatics
    • M. Kumlin, B. Dahlen, T. Bjorck, O. Zetterstrom, E. Granstrom, and S.E. Dahlen Urinary excretion of leukotriene E4 and 11-dehydro-thromboxane B2 in response to bronchial provocations with allergen, aspirin, leukotriene D4, and histamine in asthmatics Am. Rev. Respir. Dis. 146 1992 96 103
    • (1992) Am. Rev. Respir. Dis. , vol.146 , pp. 96-103
    • Kumlin, M.1    Dahlen, B.2    Bjorck, T.3    Zetterstrom, O.4    Granstrom, E.5    Dahlen, S.E.6
  • 80
    • 0028910094 scopus 로고
    • Role of thromboxane A2 synthetase inhibitors in the treatment of patients with bronchial asthma
    • M. Kurosawa Role of thromboxane A2 synthetase inhibitors in the treatment of patients with bronchial asthma Clin. Ther. 17 1995 2 11 discussion 11
    • (1995) Clin. Ther. , vol.17 , pp. 2-11
    • Kurosawa, M.1
  • 82
    • 0026683661 scopus 로고
    • Effects of a thromboxane-receptor antagonist, BAY u 3405, on prostaglandin D2- and exercise-induced bronchoconstriction
    • H. Magnussen, S. Boerger, K. Templin, and A.R. Baunack Effects of a thromboxane-receptor antagonist, BAY u 3405, on prostaglandin D2- and exercise-induced bronchoconstriction J. Allergy Clin. Immunol. 89 1992 1119 1126
    • (1992) J. Allergy Clin. Immunol. , vol.89 , pp. 1119-1126
    • Magnussen, H.1    Boerger, S.2    Templin, K.3    Baunack, A.R.4
  • 83
    • 23044460265 scopus 로고    scopus 로고
    • Identification of indole derivatives exclusively interfering with a G protein-independent signaling pathway of the prostaglandin D2 receptor CRTH2
    • J.M. Mathiesen, T. Ulven, L. Martini, L.O. Gerlach, A. Heinemann, and E. Kostenis Identification of indole derivatives exclusively interfering with a G protein-independent signaling pathway of the prostaglandin D2 receptor CRTH2 Mol. Pharmacol. 68 2005 393 402
    • (2005) Mol. Pharmacol. , vol.68 , pp. 393-402
    • Mathiesen, J.M.1    Ulven, T.2    Martini, L.3    Gerlach, L.O.4    Heinemann, A.5    Kostenis, E.6
  • 84
    • 0027453660 scopus 로고
    • Inhibition of antigen-induced airway hyperresponsiveness by a thromboxane A2 receptor antagonist (AA-2414) in Ascaris suum-allergic dogs
    • T. Matsumoto, and Y. Ashida Inhibition of antigen-induced airway hyperresponsiveness by a thromboxane A2 receptor antagonist (AA-2414) in Ascaris suum-allergic dogs Prostaglandins 46 1993 301 318
    • (1993) Prostaglandins , vol.46 , pp. 301-318
    • Matsumoto, T.1    Ashida, Y.2
  • 85
    • 0028225397 scopus 로고
    • Pharmacological modulation of immediate and late airway response and leukocyte infiltration in the guinea pig
    • T. Matsumoto, Y. Ashida, and R. Tsukuda Pharmacological modulation of immediate and late airway response and leukocyte infiltration in the guinea pig J. Pharmacol. Exp. Ther. 269 1994 1236 1244
    • (1994) J. Pharmacol. Exp. Ther. , vol.269 , pp. 1236-1244
    • Matsumoto, T.1    Ashida, Y.2    Tsukuda, R.3
  • 87
    • 0025999792 scopus 로고
    • BAY u3405, a potent and selective thromboxane A2 receptor antagonist on airway smooth muscle in vitro
    • M.G. McKenniff, P. Norman, N.J. Cuthbert, and P.J. Gardiner BAY u3405, a potent and selective thromboxane A2 receptor antagonist on airway smooth muscle in vitro Br. J. Pharmacol. 104 1991 585 590
    • (1991) Br. J. Pharmacol. , vol.104 , pp. 585-590
    • McKenniff, M.G.1    Norman, P.2    Cuthbert, N.J.3    Gardiner, P.J.4
  • 88
    • 23044463582 scopus 로고    scopus 로고
    • Inhibitory effect of the 4-aminotetrahydroquinoline derivatives, selective chemoattractant receptor-homologous molecule expressed on T helper 2 cell antagonists, on eosinophil migration induced by prostaglandin D2
    • H. Mimura, T. Ikemura, O. Kotera, M. Sawada, S. Tashiro, E. Fuse, K. Ueno, H. Manabe, E. Ohshima, A. Karasawa, and H. Miyaji Inhibitory effect of the 4-aminotetrahydroquinoline derivatives, selective chemoattractant receptor-homologous molecule expressed on T helper 2 cell antagonists, on eosinophil migration induced by prostaglandin D2 J. Pharmacol. Exp. Ther. 314 2005 244 251
    • (2005) J. Pharmacol. Exp. Ther. , vol.314 , pp. 244-251
    • Mimura, H.1    Ikemura, T.2    Kotera, O.3    Sawada, M.4    Tashiro, S.5    Fuse, E.6    Ueno, K.7    Manabe, H.8    Ohshima, E.9    Karasawa, A.10    Miyaji, H.11
  • 93
    • 0030065476 scopus 로고    scopus 로고
    • The isoprostanes. Current knowledge and directions for future research
    • J.D. Morrow, and L.J. Roberts II The isoprostanes. Current knowledge and directions for future research Biochem. Pharmacol. 51 1996 1 9
    • (1996) Biochem. Pharmacol. , vol.51 , pp. 1-9
    • Morrow, J.D.1    Roberts II, L.J.2
  • 94
    • 0030963753 scopus 로고    scopus 로고
    • The isoprostanes: Unique bioactive products of lipid peroxidation
    • J.D. Morrow, and L.J. Roberts The isoprostanes: unique bioactive products of lipid peroxidation Prog. Lipid Res. 36 1997 1 21
    • (1997) Prog. Lipid Res. , vol.36 , pp. 1-21
    • Morrow, J.D.1    Roberts, L.J.2
  • 95
    • 13144259660 scopus 로고    scopus 로고
    • Mass spectrometric quantification of F2-isoprostanes in biological fluids and tissues as measure of oxidant stress
    • J.D. Morrow, and L.J. Roberts II Mass spectrometric quantification of F2-isoprostanes in biological fluids and tissues as measure of oxidant stress Methods Enzymol. 300 1999 3 12
    • (1999) Methods Enzymol. , vol.300 , pp. 3-12
    • Morrow, J.D.1    Roberts II, L.J.2
  • 96
    • 0037115255 scopus 로고    scopus 로고
    • The isoprostanes: Their role as an index of oxidant stress status in human pulmonary disease
    • J.D. Morrow, and L.J. Roberts The isoprostanes: their role as an index of oxidant stress status in human pulmonary disease Am. J. Respir. Crit. Care Med. 166 2002 S25 S30
    • (2002) Am. J. Respir. Crit. Care Med. , vol.166
    • Morrow, J.D.1    Roberts, L.J.2
  • 97
    • 0025572704 scopus 로고
    • A series of prostaglandin F2-like compounds are produced in vivo in humans by a non-cyclooxygenase, free radical-catalyzed mechanism
    • J.D. Morrow, K.E. Hill, R.F. Burk, T.M. Nammour, K.F. Badr, and L.J. Roberts II A series of prostaglandin F2-like compounds are produced in vivo in humans by a non-cyclooxygenase, free radical-catalyzed mechanism Proc. Natl. Acad. Sci. U. S. A. 87 1990 9383 9387
    • (1990) Proc. Natl. Acad. Sci. U. S. A. , vol.87 , pp. 9383-9387
    • Morrow, J.D.1    Hill, K.E.2    Burk, R.F.3    Nammour, T.M.4    Badr, K.F.5    Roberts II, L.J.6
  • 98
    • 0029817359 scopus 로고    scopus 로고
    • Nonenzymatic free radical-catalyzed generation of thromboxane-like compounds (isothromboxanes) in vivo
    • J.D. Morrow, J.A. Awad, A. Wu, W.E. Zackert, V.C. Daniel, and L.J. Roberts II Nonenzymatic free radical-catalyzed generation of thromboxane-like compounds (isothromboxanes) in vivo J. Biol. Chem. 271 1996 23185 23190
    • (1996) J. Biol. Chem. , vol.271 , pp. 23185-23190
    • Morrow, J.D.1    Awad, J.A.2    Wu, A.3    Zackert, W.E.4    Daniel, V.C.5    Roberts II, L.J.6
  • 101
    • 0038138607 scopus 로고    scopus 로고
    • The second PGD(2) receptor CRTH2: Structure, properties, and functions in leukocytes
    • K. Nagata, and H. Hirai The second PGD(2) receptor CRTH2: structure, properties, and functions in leukocytes Prostaglandins Leukot. Essent. Fat. Acids 69 2003 169 177
    • (2003) Prostaglandins Leukot. Essent. Fat. Acids , vol.69 , pp. 169-177
    • Nagata, K.1    Hirai, H.2
  • 102
    • 0032829392 scopus 로고    scopus 로고
    • CRTH2, an orphan receptor of T-helper-2-cells, is expressed on basophils and eosinophils and responds to mast cell-derived factor(s)
    • K. Nagata, H. Hirai, K. Tanaka, K. Ogawa, T. Aso, K. Sugamura, M. Nakamura, and S. Takano CRTH2, an orphan receptor of T-helper-2-cells, is expressed on basophils and eosinophils and responds to mast cell-derived factor(s) FEBS Lett. 459 1999 195 199
    • (1999) FEBS Lett. , vol.459 , pp. 195-199
    • Nagata, K.1    Hirai, H.2    Tanaka, K.3    Ogawa, K.4    Aso, T.5    Sugamura, K.6    Nakamura, M.7    Takano, S.8
  • 103
    • 0028650306 scopus 로고
    • Research and development of ozagrel, a highly selective inhibitor of TXA2 synthase
    • M. Nakazawa, K. Iizuka, A. Ujiie, S. Hiraku, and S. Ohki Research and development of ozagrel, a highly selective inhibitor of TXA2 synthase Yakugaku Zasshi 114 1994 911 933
    • (1994) Yakugaku Zasshi , vol.114 , pp. 911-933
    • Nakazawa, M.1    Iizuka, K.2    Ujiie, A.3    Hiraku, S.4    Ohki, S.5
  • 104
    • 0028228508 scopus 로고
    • CDNA cloning of a mouse prostacyclin receptor. Multiple signaling pathways and expression in thymic medulla
    • T. Namba, H. Oida, Y. Sugimoto, A. Kakizuka, M. Negishi, A. Ichikawa, and S. Narumiya cDNA cloning of a mouse prostacyclin receptor. Multiple signaling pathways and expression in thymic medulla J. Biol. Chem. 269 1994 9986 9992
    • (1994) J. Biol. Chem. , vol.269 , pp. 9986-9992
    • Namba, T.1    Oida, H.2    Sugimoto, Y.3    Kakizuka, A.4    Negishi, M.5    Ichikawa, A.6    Narumiya, S.7
  • 107
    • 0032823306 scopus 로고    scopus 로고
    • Prostanoid receptors: Structures, properties, and functions
    • S. Narumiya, Y. Sugimoto, and F. Ushikubi Prostanoid receptors: structures, properties, and functions Physiol. Rev. 79 1999 1193 1226
    • (1999) Physiol. Rev. , vol.79 , pp. 1193-1226
    • Narumiya, S.1    Sugimoto, Y.2    Ushikubi, F.3
  • 108
    • 0031559584 scopus 로고    scopus 로고
    • Evidence for involvement of NF-kappaB in the transcriptional control of COX-2 gene expression by IL-1beta
    • R. Newton, L.M. Kuitert, M. Bergmann, I.M. Adcock, and P.J. Barnes Evidence for involvement of NF-kappaB in the transcriptional control of COX-2 gene expression by IL-1beta Biochem. Biophys. Res. Commun. 237 1997 28 32
    • (1997) Biochem. Biophys. Res. Commun. , vol.237 , pp. 28-32
    • Newton, R.1    Kuitert, L.M.2    Bergmann, M.3    Adcock, I.M.4    Barnes, P.J.5
  • 109
    • 0026050108 scopus 로고
    • Prostanoid contractions in human isolated pulmonary muscle preparations: Inhibition by BAY u3405
    • X. Norel, C. Labat, P. Gardiner, and C. Brink Prostanoid contractions in human isolated pulmonary muscle preparations: inhibition by BAY u3405 Adv. Prostaglandin Thromboxane Leukotriene Res. 21A 1991 473 476
    • (1991) Adv. Prostaglandin Thromboxane Leukotriene Res. , vol.21 , pp. 473-476
    • Norel, X.1    Labat, C.2    Gardiner, P.3    Brink, C.4
  • 110
    • 0025938084 scopus 로고
    • Inhibitory effects of BAY u3405 on prostanoid-induced contractions in human isolated bronchial and pulmonary arterial muscle preparations
    • X. Norel, C. Labat, P.J. Gardiner, and C. Brink Inhibitory effects of BAY u3405 on prostanoid-induced contractions in human isolated bronchial and pulmonary arterial muscle preparations Br. J. Pharmacol. 104 1991 591 595
    • (1991) Br. J. Pharmacol. , vol.104 , pp. 591-595
    • Norel, X.1    Labat, C.2    Gardiner, P.J.3    Brink, C.4
  • 111
    • 0026396640 scopus 로고
    • BAY u3405 is a potent and competitive antagonist of U46619, PGD2 and 9 alpha, 11 beta PGF2 alpha-induced contractions of airway smooth muscle
    • P. Norman, N.J. Cuthbert, P.J. Gardiner, and M.G. McKenniff BAY u3405 is a potent and competitive antagonist of U46619, PGD2 and 9 alpha, 11 beta PGF2 alpha-induced contractions of airway smooth muscle Ann. N.Y. Acad. Sci. 629 1991 396 398
    • (1991) Ann. N.Y. Acad. Sci. , vol.629 , pp. 396-398
    • Norman, P.1    Cuthbert, N.J.2    Gardiner, P.J.3    McKenniff, M.G.4
  • 112
    • 0025105498 scopus 로고
    • Immunohistochemical localization of thromboxane synthase in human tissues
    • R. Nusing, R. Lesch, and V. Ullrich Immunohistochemical localization of thromboxane synthase in human tissues Eicosanoids 3 1990 53 58
    • (1990) Eicosanoids , vol.3 , pp. 53-58
    • Nusing, R.1    Lesch, R.2    Ullrich, V.3
  • 114
    • 0035860491 scopus 로고    scopus 로고
    • Effect of E3040, an inhibitor of 5-lipoxygenase and thromboxane synthase, on rat bowel damage induced by lipopolysaccharide
    • K. Oketani, T. Inoue, and M. Murakami Effect of E3040, an inhibitor of 5-lipoxygenase and thromboxane synthase, on rat bowel damage induced by lipopolysaccharide Eur. J. Pharmacol. 427 2001 159 166
    • (2001) Eur. J. Pharmacol. , vol.427 , pp. 159-166
    • Oketani, K.1    Inoue, T.2    Murakami, M.3
  • 115
    • 0035933411 scopus 로고    scopus 로고
    • In vitro effects of E3040, a dual inhibitor of 5-lipoxygenase and thromboxane A(2) synthetase, on eicosanoid production
    • K. Oketani, N. Nagakura, K. Harada, and T. Inoue In vitro effects of E3040, a dual inhibitor of 5-lipoxygenase and thromboxane A(2) synthetase, on eicosanoid production Eur. J. Pharmacol. 422 2001 209 216
    • (2001) Eur. J. Pharmacol. , vol.422 , pp. 209-216
    • Oketani, K.1    Nagakura, N.2    Harada, K.3    Inoue, T.4
  • 116
    • 0033973730 scopus 로고    scopus 로고
    • Effects of some isoprostanes on the human umbilical artery in vitro
    • L. Oliveira, N.A. Stallwood, and D.J. Crankshaw Effects of some isoprostanes on the human umbilical artery in vitro Br. J. Pharmacol. 129 2000 509 514
    • (2000) Br. J. Pharmacol. , vol.129 , pp. 509-514
    • Oliveira, L.1    Stallwood, N.A.2    Crankshaw, D.J.3
  • 117
    • 0029121221 scopus 로고
    • Inflammatory cell number and mediators in bronchoalveolar lavage fluid and peripheral blood in subjects with asthma with increased nocturnal airways narrowing
    • Y. Oosterhoff, H.F. Kauffman, B. Rutgers, F.J. Zijlstra, G.H. Koeter, and D.S. Postma Inflammatory cell number and mediators in bronchoalveolar lavage fluid and peripheral blood in subjects with asthma with increased nocturnal airways narrowing J. Allergy Clin. Immunol. 96 1995 219 229
    • (1995) J. Allergy Clin. Immunol. , vol.96 , pp. 219-229
    • Oosterhoff, Y.1    Kauffman, H.F.2    Rutgers, B.3    Zijlstra, F.J.4    Koeter, G.H.5    Postma, D.S.6
  • 118
    • 0033605423 scopus 로고    scopus 로고
    • Internalization of the TXA2 receptor alpha and beta isoforms. Role of the differentially spliced COOH terminus in agonist-promoted receptor internalization
    • J.L. Parent, P. Labrecque, M.J. Orsini, and J.L. Benovic Internalization of the TXA2 receptor alpha and beta isoforms. Role of the differentially spliced COOH terminus in agonist-promoted receptor internalization J. Biol. Chem. 274 1999 8941 8948
    • (1999) J. Biol. Chem. , vol.274 , pp. 8941-8948
    • Parent, J.L.1    Labrecque, P.2    Orsini, M.J.3    Benovic, J.L.4
  • 120
    • 0032446729 scopus 로고    scopus 로고
    • Chronic obstructive pulmonary disease is associated with an increase in urinary levels of isoprostane F2alpha-III, an index of oxidant stress
    • D. Pratico, S. Basili, M. Vieri, C. Cordova, F. Violi, and G.A. Fitzgerald Chronic obstructive pulmonary disease is associated with an increase in urinary levels of isoprostane F2alpha-III, an index of oxidant stress Am. J. Respir. Crit. Care Med. 158 1998 1709 1714
    • (1998) Am. J. Respir. Crit. Care Med. , vol.158 , pp. 1709-1714
    • Pratico, D.1    Basili, S.2    Vieri, M.3    Cordova, C.4    Violi, F.5    Fitzgerald, G.A.6
  • 123
    • 0027936171 scopus 로고
    • Alternative splicing produces a divergent cytoplasmic tail in the human endothelial thromboxane A2 receptor
    • M.K. Raychowdhury, M. Yukawa, L.J. Collins, S.H. McGrail, K.C. Kent, and J.A. Ware Alternative splicing produces a divergent cytoplasmic tail in the human endothelial thromboxane A2 receptor J. Biol. Chem. 269 1994 19256 19261
    • (1994) J. Biol. Chem. , vol.269 , pp. 19256-19261
    • Raychowdhury, M.K.1    Yukawa, M.2    Collins, L.J.3    McGrail, S.H.4    Kent, K.C.5    Ware, J.A.6
  • 126
    • 0036016108 scopus 로고    scopus 로고
    • E3040 sulphate, a novel thromboxane synthase inhibitor, blocks the Cl-secretion induced by platelet-activating factor in isolated rat colon
    • H. Sakai, T. Suzuki, M. Murota, K. Oketani, T. Uchiumi, M. Murakami, and N. Takeguchi E3040 sulphate, a novel thromboxane synthase inhibitor, blocks the Cl-secretion induced by platelet-activating factor in isolated rat colon Br. J. Pharmacol. 136 2002 383 390
    • (2002) Br. J. Pharmacol. , vol.136 , pp. 383-390
    • Sakai, H.1    Suzuki, T.2    Murota, M.3    Oketani, K.4    Uchiumi, T.5    Murakami, M.6    Takeguchi, N.7
  • 127
    • 0027992551 scopus 로고
    • Pharmacological studies of platelet-activating factor (PAF)-induced augmentation of response to histamine in guinea-pigs
    • T. Sakurai, S. Yamaguchi, T. Iwama, and H. Nagai Pharmacological studies of platelet-activating factor (PAF)-induced augmentation of response to histamine in guinea-pigs Prostaglandins Leukot. Essent. Fat. Acids 51 1994 95 99
    • (1994) Prostaglandins Leukot. Essent. Fat. Acids , vol.51 , pp. 95-99
    • Sakurai, T.1    Yamaguchi, S.2    Iwama, T.3    Nagai, H.4
  • 129
    • 0025880172 scopus 로고
    • The G protein coupled to the thromboxane A2 receptor in human platelets is a member of the novel Gq family
    • A. Shenker, P. Goldsmith, C.G. Unson, and A.M. Spiegel The G protein coupled to the thromboxane A2 receptor in human platelets is a member of the novel Gq family J. Biol. Chem. 266 1991 9309 9313
    • (1991) J. Biol. Chem. , vol.266 , pp. 9309-9313
    • Shenker, A.1    Goldsmith, P.2    Unson, C.G.3    Spiegel, A.M.4
  • 130
    • 0024462135 scopus 로고
    • Quinones. 4. Novel eicosanoid antagonists: Synthesis and pharmacological evaluation
    • M. Shiraishi, K. Kato, S. Terao, Y. Ashida, Z. Terashita, and G. Kito Quinones. 4. Novel eicosanoid antagonists: synthesis and pharmacological evaluation J. Med. Chem. 32 1989 2214 2221
    • (1989) J. Med. Chem. , vol.32 , pp. 2214-2221
    • Shiraishi, M.1    Kato, K.2    Terao, S.3    Ashida, Y.4    Terashita, Z.5    Kito, G.6
  • 132
    • 0026761179 scopus 로고
    • Prostanoid biosynthesis and mechanisms of action
    • W.L. Smith Prostanoid biosynthesis and mechanisms of action Am. J. Physiol. 263 1992 F181 F191
    • (1992) Am. J. Physiol. , vol.263
    • Smith, W.L.1
  • 135
    • 0037382497 scopus 로고    scopus 로고
    • An orally bioavailable small molecule antagonist of CRTH2, ramatroban (BAY u3405), inhibits prostaglandin D2-induced eosinophil migration in vitro
    • H. Sugimoto, M. Shichijo, T. Iino, Y. Manabe, A. Watanabe, M. Shimazaki, F. Gantner, and K.B. Bacon An orally bioavailable small molecule antagonist of CRTH2, ramatroban (BAY u3405), inhibits prostaglandin D2-induced eosinophil migration in vitro J. Pharmacol. Exp. Ther. 305 2003 347 352
    • (2003) J. Pharmacol. Exp. Ther. , vol.305 , pp. 347-352
    • Sugimoto, H.1    Shichijo, M.2    Iino, T.3    Manabe, Y.4    Watanabe, A.5    Shimazaki, M.6    Gantner, F.7    Bacon, K.B.8
  • 137
    • 0033943849 scopus 로고    scopus 로고
    • Effect of a thromboxane A(2) antagonist on sputum production and its physicochemical properties in patients with mild to moderate asthma
    • J. Tamaoki, M. Kondo, J. Nakata, Y. Nagano, K. Isono, and A. Nagai Effect of a thromboxane A(2) antagonist on sputum production and its physicochemical properties in patients with mild to moderate asthma Chest 118 2000 73 79
    • (2000) Chest , vol.118 , pp. 73-79
    • Tamaoki, J.1    Kondo, M.2    Nakata, J.3    Nagano, Y.4    Isono, K.5    Nagai, A.6
  • 140
    • 0034943516 scopus 로고    scopus 로고
    • Mixed messages: Modulation of inflammation and immune responses by prostaglandins and thromboxanes
    • S.L. Tilley, T.M. Coffman, and B.H. Koller Mixed messages: modulation of inflammation and immune responses by prostaglandins and thromboxanes J. Clin. Invest. 108 2001 15 23
    • (2001) J. Clin. Invest. , vol.108 , pp. 15-23
    • Tilley, S.L.1    Coffman, T.M.2    Koller, B.H.3
  • 141
    • 0025768647 scopus 로고
    • Efficacy and toxicity of thromboxane synthetase inhibitor for cerebral vasospasm after subarachnoid hemorrhage
    • K. Tokiyoshi, T. Ohnishi, and Y. Nii Efficacy and toxicity of thromboxane synthetase inhibitor for cerebral vasospasm after subarachnoid hemorrhage Surg. Neurol. 36 1991 112 118
    • (1991) Surg. Neurol. , vol.36 , pp. 112-118
    • Tokiyoshi, K.1    Ohnishi, T.2    Nii, Y.3
  • 142
    • 0020466238 scopus 로고
    • Possible involvement of thromboxane in bronchoconstrictive and hypertensive effects of LTC4 and LTD4 in guinea pigs
    • A. Ueno, K. Tanaka, and M. Katori Possible involvement of thromboxane in bronchoconstrictive and hypertensive effects of LTC4 and LTD4 in guinea pigs Prostaglandins 23 1982 865 880
    • (1982) Prostaglandins , vol.23 , pp. 865-880
    • Ueno, A.1    Tanaka, K.2    Katori, M.3
  • 144
    • 3242816263 scopus 로고    scopus 로고
    • Clinical implications of airway inflammation in mild intermittent asthma
    • quiz 595-587, 658.
    • van den Toorn, L.M., 2004. Clinical implications of airway inflammation in mild intermittent asthma. Ann. Allergy Asthma Immunol. 92, 589-594; quiz 595-587, 658.
    • (2004) Ann. Allergy Asthma Immunol. , vol.92 , pp. 589-594
    • Van Den Toorn, L.M.1
  • 145
    • 0347301751 scopus 로고    scopus 로고
    • Cloning and localization of hFP(S): A six-transmembrane mRNA splice variant of the human FP prostanoid receptor
    • G.A. Vielhauer, H. Fujino, and J.W. Regan Cloning and localization of hFP(S): a six-transmembrane mRNA splice variant of the human FP prostanoid receptor Arch. Biochem. Biophys. 421 2004 175 185
    • (2004) Arch. Biochem. Biophys. , vol.421 , pp. 175-185
    • Vielhauer, G.A.1    Fujino, H.2    Regan, J.W.3
  • 147
    • 0035671188 scopus 로고    scopus 로고
    • Prostanoid EP(1)- and TP-receptors involved in the contraction of human pulmonary veins
    • L. Walch, V. de Montpreville, C. Brink, and X. Norel Prostanoid EP(1)- and TP-receptors involved in the contraction of human pulmonary veins Br. J. Pharmacol. 134 2001 1671 1678
    • (2001) Br. J. Pharmacol. , vol.134 , pp. 1671-1678
    • Walch, L.1    De Montpreville, V.2    Brink, C.3    Norel, X.4
  • 149
    • 0031017337 scopus 로고    scopus 로고
    • Arachidonic acid metabolites: Mediators of inflammation in asthma
    • S.E. Wenzel Arachidonic acid metabolites: mediators of inflammation in asthma Pharmacotherapy 17 1997 3S 12S
    • (1997) Pharmacotherapy , vol.17
    • Wenzel, S.E.1
  • 150
    • 0024548854 scopus 로고
    • Spectrum of prostanoid release after bronchoalveolar allergen challenge in atopic asthmatics and in control groups. An alteration in the ratio of bronchoconstrictive to bronchoprotective mediators
    • S.E. Wenzel, J.Y. Westcott, H.R. Smith, and G.L. Larsen Spectrum of prostanoid release after bronchoalveolar allergen challenge in atopic asthmatics and in control groups. An alteration in the ratio of bronchoconstrictive to bronchoprotective mediators Am. Rev. Respir. Dis. 139 1989 450 457
    • (1989) Am. Rev. Respir. Dis. , vol.139 , pp. 450-457
    • Wenzel, S.E.1    Westcott, J.Y.2    Smith, H.R.3    Larsen, G.L.4
  • 151
    • 0025819314 scopus 로고
    • Bronchoalveolar lavage fluid mediator levels 5 minutes after allergen challenge in atopic subjects with asthma: Relationship to the development of late asthmatic responses
    • S.E. Wenzel, J.Y. Westcott, and G.L. Larsen Bronchoalveolar lavage fluid mediator levels 5 minutes after allergen challenge in atopic subjects with asthma: relationship to the development of late asthmatic responses J. Allergy Clin. Immunol. 87 1991 540 548
    • (1991) J. Allergy Clin. Immunol. , vol.87 , pp. 540-548
    • Wenzel, S.E.1    Westcott, J.Y.2    Larsen, G.L.3
  • 152
  • 153
    • 0033799106 scopus 로고    scopus 로고
    • Lipid peroxidation as determined by plasma isoprostanes is related to disease severity in mild asthma
    • L.G. Wood, D.A. Fitzgerald, P.G. Gibson, D.M. Cooper, and M.L. Garg Lipid peroxidation as determined by plasma isoprostanes is related to disease severity in mild asthma Lipids 35 2000 967 974
    • (2000) Lipids , vol.35 , pp. 967-974
    • Wood, L.G.1    Fitzgerald, D.A.2    Gibson, P.G.3    Cooper, D.M.4    Garg, M.L.5
  • 155
    • 0033371302 scopus 로고    scopus 로고
    • Mechanism of the uricosuric action of E3040, a drug used to treat inflammatory bowel disease II: Study using DBA/2N mice
    • H. Yamada, H. Kotaki, H. Furitsu, Y. Sawada, and T. Iga Mechanism of the uricosuric action of E3040, a drug used to treat inflammatory bowel disease II: study using DBA/2N mice Biopharm. Drug Dispos. 20 1999 271 276
    • (1999) Biopharm. Drug Dispos. , vol.20 , pp. 271-276
    • Yamada, H.1    Kotaki, H.2    Furitsu, H.3    Sawada, Y.4    Iga, T.5
  • 156
    • 0026110807 scopus 로고
    • Changes of thromboxane A2 (TXA2) and prostacyclin (PGI2) in COPD patients with pulmonary hypertension
    • Zheng, L., Duan, S.F., Zhang, Z.X., 1991. Changes of thromboxane A2 (TXA2) and prostacyclin (PGI2) in COPD patients with pulmonary hypertension. Zhonghua Nei Ke Za Zhi 30, 91-93, 126
    • (1991) Zhonghua Nei Ke Za Zhi , vol.30 , pp. 91-93
    • Zheng, L.1    Duan, S.F.2    Zhang, Z.X.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.