The human thromboxane A2 receptor α isoform (TPα) functionally couples to the G proteins G(q) and G11 in vivo and is activated by the isoprostane 8-epi prostaglandin F(2α)

Journal of Pharmacology and Experimental Therapeutics

Volumn 281, Issue 2, 1997, Pages 957-964

  Kinsella, B Therese ^a   O'Mahony, Daniel J ^a,b   Fitzgerald, Garret A ^c  

^a UNIVERSITY COLLEGE DUBLIN   (Ireland)

^b ELAN PHARMACEUTICALS   (United States)

^c UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

15 HYDROXY 11ALPHA,9ALPHA EPOXYMETHANOPROSTA 5,13 DIENOIC ACID; 7 [3 [(4 PHENYLSEMICARBAZIDO)METHYL] 7 OXABICYCLO[2.2.1]HEPT 2 YL] 5 HEPTENOIC ACID; ISOPROSTANE 8 EPIPROSTAGLANDIN F2 ALPHA; ISOPROSTANE DERIVATIVE; THROMBOXANE A2 RECEPTOR; UNCLASSIFIED DRUG; 8 EPI PROSTAGLANDIN F2ALPHA; 8-EPI-PROSTAGLANDIN F2ALPHA; CALCIUM; COMPLEMENTARY DNA; DRUG DERIVATIVE; GUANINE NUCLEOTIDE BINDING PROTEIN; PROSTAGLANDIN ENDOPEROXIDE; PROSTAGLANDIN F2 ALPHA; RECOMBINANT PROTEIN; THROMBOXANE A2; THROMBOXANE RECEPTOR;

ARTICLE; BINDING AFFINITY; DESENSITIZATION; DNA POLYMORPHISM; DNA SEQUENCE; ENDOTHELIUM CELL; LIGAND BINDING; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROSTAGLANDIN METABOLISM; PROTEIN BINDING; PROTEIN PHOSPHORYLATION; CELL LINE; DRUG EFFECT; GENETICS; HUMAN; METABOLISM;

15-HYDROXY-11 ALPHA,9 ALPHA-(EPOXYMETHANO)PROSTA-5,13-DIENOIC ACID; CALCIUM; CELL LINE; DINOPROST; DNA, COMPLEMENTARY; GTP-BINDING PROTEINS; HUMANS; PROSTAGLANDIN ENDOPEROXIDES, SYNTHETIC; RECEPTORS, THROMBOXANE; RECOMBINANT PROTEINS; THROMBOXANE A2;

EID: 0030610439     PISSN: 00223565     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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